Differentiating Mild Cognitive Impairment, Alzheimer's Disease, and Dementia With Lewy Bodies Using Cingulate Island Sign on Perfusion IMP-SPECT.

abstract：INTRODUCTION:In tinnitus treatment, there is a tendency to shift from a "one size fits all" to a more individual, patient-tailored approach. Insight in the heterogeneity of the tinnitus spectrum might improve the management of tinnitus patients in terms of choice of treatment and identification of patients with severe ...

journal_title：Frontiers in neurology

authors： van den Berge MJC,Free RH,Arnold R,de Kleine E,Hofman R,van Dijk JMC,van Dijk P

更新日期：2017-04-03 00:00:00

abstract：:Background: Most travelers experience Jet Lag Disorder (JLD) symptoms due to misalignment of their circadian rhythms with respect to the new time zone. We assessed the efficacy and safety of tasimelteon (HETLIOZ®) in healthy participants using a laboratory model of JLD induced by an 8-h phase advance of the sleep-wake...

journal_title：Frontiers in neurology

authors： Polymeropoulos CM,Mohrman MA,Keefe MS,Brzezynski JL,Wang J,Prokosch LS,Polymeropoulos VM,Xiao C,Birznieks G,Polymeropoulos MH

更新日期：2020-07-09 00:00:00

abstract：:Skeletal muscle is an essential regulator of energy homeostasis and a potent coordinator of exercise-induced adaptations in other organs including the liver, fat or the brain. Skeletal muscle-initiated crosstalk with other tissues is accomplished though the secretion of myokines, protein hormones which can exert autoc...

journal_title：Frontiers in neurology

authors： Delezie J,Handschin C

更新日期：2018-08-24 00:00:00

abstract：:Over the last two decades, many experimental and clinical studies have provided solid evidence that alpha-synuclein (α-syn), a small, natively unfolded protein, is closely related to Parkinson's disease (PD) pathology. To provide an overview on the different roles of this protein, here we propose a synopsis of seminal...

journal_title：Frontiers in neurology

authors： Ghiglieri V,Calabrese V,Calabresi P

更新日期：2018-05-04 00:00:00

abstract：BACKGROUND:Public awareness of and attitude toward disease is an important issue for patients. Public awareness of essential tremor (ET) has never been studied. METHODS:We administered a 10-min, 31-item questionnaire to 250 consecutive enrollees. These included three samples carefully chosen to have a potential range ...

journal_title：Frontiers in neurology

authors： Shalaby S,Indes J,Keung B,Gottschalk CH,Machado D,Patel A,Robakis D,Louis ED

更新日期：2016-04-22 00:00:00

abstract：Introduction:Transcranial high-resolution ultrasonography reliably allows diagnosis and monitoring of intracerebral hemorrhage in adults. Sonographic monitoring of subdural hematoma (SDH) has not been evaluated in adults so far. This study investigates the reliability of transcranial gray-scale sonography (TGS) in moni...

journal_title：Frontiers in neurology

authors： Niesen WD,Rosenkranz M,Weiller C

更新日期：2018-05-28 00:00:00

abstract：:Background and aims: The pathophysiology of hippocampal enlarged perivascular spaces (H-EPVS) and its relationship to cognitive impairment is largely unknown. This study aimed to investigate the relationship between H-EPVS and cognition in non-dementic elderly population. Methods: A total of 109 subjects were prospect...

journal_title：Frontiers in neurology

authors： Sim JE,Park MS,Shin HY,Jang HS,Won HH,Seo SW,Seo WK,Kim BJ,Kim GM

更新日期：2020-09-29 00:00:00

abstract：:Periodontitis is an oral inflammatory disease and may contribute to low-grade systemic inflammation. Based on the contribution of periodontitis to systemic inflammation and the potential role of systemic inflammation in neuroinflammation, many epidemiological studies have investigated a possible association between pe...

journal_title：Frontiers in neurology

authors： Nascimento PC,Castro MML,Magno MB,Almeida APCPSC,Fagundes NCF,Maia LC,Lima RR

更新日期：2019-04-24 00:00:00

abstract：:There is currently no therapeutic drug treatment for traumatic brain injury (TBI) despite decades of experimental clinical trials. This may be because the mechanistic pathways for improving TBI outcomes have yet to be identified and exploited. As such, there remains a need to seek out new molecular targets and their d...

journal_title：Frontiers in neurology

authors： Hook G,Jacobsen JS,Grabstein K,Kindy M,Hook V

更新日期：2015-09-02 00:00:00

abstract：:Background: Increasing evidence indicates that early radiation-induced subtle cerebral changes may be the precursors to permanent brain dysfunction at the late-delayed (LDS) post-radiotherapy (RT) stage. In this study, we aim to track the RT-related longitudinal brain activity in nasopharyngeal carcinoma (NPC) patient...

journal_title：Frontiers in neurology

authors： Yang Y,Lin X,Li J,Han L,Li Z,Liu S,Hou G,Xie C,Lv X,Qiu Y

更新日期：2019-07-16 00:00:00

abstract：:Increasing evidence suggests an association between gastrointestinal (GI) disorders and susceptibility and progress of Parkinson's disease (PD). Gut-brain axis has been proposed to play important roles in the pathogenesis of PD, though the exact pathophysiologic mechanism has yet to be elucidated. Here, we discuss the...

journal_title：Frontiers in neurology

authors： Chao YX,Gulam MY,Chia NSJ,Feng L,Rotzschke O,Tan EK

更新日期：2020-08-25 00:00:00

abstract：:Mutations in the Potassium channel subfamily T member 1 (KCNT1) gene have been reported in a range of epileptic encephalopathies. Here we report the case of a 12-year-old male suffering from multiple types of epileptic seizures and cognitive decline from the age of 10. The patient had four types of epileptic seizures,...

journal_title：Frontiers in neurology

authors： Jia Y,Lin Y,Li J,Li M,Zhang Y,Hou Y,Liu A,Zhang L,Li L,Xiang P,Ye J,Huang Z,Wang Y

更新日期：2019-02-05 00:00:00

abstract：:Spontaneous intracerebral hemorrhage (SICH) is the most lethal type of stroke. Half of these deaths occur within the acute phase. Frequently observed deterioration during the acute phase is often due to rebleeding or peri-hematomal expansion. The exact pathogenesis that leads to rebleeding or peri-hemorrhagic edema re...

journal_title：Frontiers in neurology

authors： Babi MA,James ML

更新日期：2017-01-19 00:00:00

abstract：:Primary progressive aphasia (PPA) is a neurodegenerative disease characterized by declining language ability. However, the difficulty in defining the central clinical features in its earliest stage and establishing the dynamics of its progression has led to controversy. We report a 71-year-old man with Han language su...

journal_title：Frontiers in neurology

authors： Liu X,He F,Chen Z,Liu P,Peng G

更新日期：2018-02-16 00:00:00

abstract：:The mechanisms involved in traumatic brain injury have yet to be fully characterized. One mechanism that, especially in high-energy trauma, could be of importance is cavitation. Cavitation can be described as a process of vaporization, bubble generation, and bubble implosion as a result of a decrease and subsequent in...

journal_title：Frontiers in neurology

authors： Cao Y,Risling M,Malm E,Sondén A,Bolling MF,Sköld MK

更新日期：2016-02-01 00:00:00

abstract：:For epileptic patients requiring resective surgery, a modality called stereo-electroencephalography (SEEG) may be used to monitor the patient's brain signals to help identify epileptogenic regions that generate and propagate seizures. SEEG involves the insertion of multiple depth electrodes into the patient's brain, e...

journal_title：Frontiers in neurology

authors： Greene P,Li A,González-Martínez J,Sarma SV

更新日期：2021-01-06 00:00:00

abstract：:Background: The relationship between varicella-zoster virus (VZV)-associated myelitis and aquaporin-4 immunoglobulin-G (AQP4-IgG) remains unknown. Case Report: We report a case of acute radiculomyelitis with longitudinal extensive hyperintensity signals traversing the brainstem until the upper thoracic cord in a 55-ye...

journal_title：Frontiers in neurology

authors： Eguchi H,Takeshige H,Nakajima S,Kanou M,Nakajima A,Fuse A,Fukae J,Miwa H,Shimo Y

更新日期：2020-11-23 00:00:00

abstract：Background:Cerebral microcirculation after severe head injury is heterogeneous and temporally variable. Microcirculation is dependent upon the severity of injury, and it is unclear how histology relates to cerebral regional blood flow. Objective:This study assesses the changes of cerebral microcirculation blood flow o...

journal_title：Frontiers in neurology

authors： Bellapart J,Cuthbertson K,Dunster K,Diab S,Platts DG,Raffel OC,Gabrielian L,Barnett A,Paratz J,Boots R,Fraser JF

更新日期：2018-05-07 00:00:00

abstract：:Background: Recent developments in mobile technology have enabled the investigation of human movements and mobility under natural conditions, i.e., in the home environment. Iron accumulation in the basal ganglia is deleterious in Parkinson's disease (i.e., iron accumulation with lower striatal level of dopamine). The ...

journal_title：Frontiers in neurology

authors： Hopfner F,Hobert MA,Maetzler C,Hansen C,Pham MH,Moreau C,Berg D,Devos D,Maetzler W,Fair-Park II study group.

更新日期：2019-08-08 00:00:00

abstract：:Importance: Coronavirus disease 2019 (COVID-19) is a newly emerging infectious disease that has caused a global pandemic. The presenting symptoms are mainly respiratory symptom, yet studies have reported nervous system involvement in the disease. A systematic review and meta-analysis of these studies are required to u...

journal_title：Frontiers in neurology

authors： Pinzon RT,Wijaya VO,Buana RB,Al Jody A,Nunsio PN

更新日期：2020-05-29 00:00:00

abstract：:Studies of traumatic brain injury from all causes have found evidence of chronic hypopituitarism, defined by deficient production of one or more pituitary hormones at least 1 year after injury, in 25-50% of cases. Most studies found the occurrence of posttraumatic hypopituitarism (PTHP) to be unrelated to injury sever...

journal_title：Frontiers in neurology

authors： Wilkinson CW,Pagulayan KF,Petrie EC,Mayer CL,Colasurdo EA,Shofer JB,Hart KL,Hoff D,Tarabochia MA,Peskind ER

更新日期：2012-02-07 00:00:00

abstract：:Alzheimer's disease is the most common neurodegenerative form of dementia that steadily worsens and eventually leads to death. Its set of symptoms include loss of cognitive function and memory decline. Structural and functional imaging methods such as CT, MRI, and PET scans play an essential role in the diagnosis proc...

journal_title：Frontiers in neurology

authors： Gionfrida L,Roginska A

更新日期：2017-12-07 00:00:00

abstract：:The aim of the present study was to evaluate the correlation between the end of an Oxford sleep resistance (OSLER) test session and a neurophysiological marker of sleep onset in Parkinson's disease (PD) patients. Single center study was conducted in PD patients with excessive daytime sleepiness [Epworth sleepiness sca...

journal_title：Frontiers in neurology

authors： Neutel D,Peralta R,Pires J,Bentes C,Ferreira JJ

更新日期：2015-09-24 00:00:00

abstract：:We describe and evaluate a pre-processing method based on a periodic spiral sampling of diffusion-gradient directions for high angular resolution diffusion magnetic resonance imaging. Our pre-processing method incorporates prior knowledge about the acquired diffusion-weighted signal, facilitating noise reduction. Peri...

journal_title：Frontiers in neurology

authors： Sepehrband F,Choupan J,Caruyer E,Kurniawan ND,Gal Y,Tieng QM,McMahon KL,Vegh V,Reutens DC,Yang Z

更新日期：2015-01-12 00:00:00

abstract：:Surface electromyography (sEMG) is a widely used technology in rehabilitation research and provides quantifiable information on the myoelectric output of a muscle. In this perspective, we discuss the barriers which have restricted the wide-spread use of sEMG in clinical rehabilitation of individuals with spinal cord i...

journal_title：Frontiers in neurology

authors： Pilkar R,Momeni K,Ramanujam A,Ravi M,Garbarini E,Forrest GF

更新日期：2020-12-18 00:00:00

abstract：:Significant advances have been made in the understanding of the numerous mechanisms involved in Parkinson's disease (PD) pathogenesis. The identification of PD pathogenic mutations and the use of different animal models have contributed to better elucidate the processes underlying the disease. Here, we report a brief ...

journal_title：Frontiers in neurology

authors： Imbriani P,Schirinzi T,Meringolo M,Mercuri NB,Pisani A

更新日期：2018-03-01 00:00:00

abstract：:Myasthenia gravis (MG) is the most common autoimmune disorder affecting the neuromuscular junction, characterized by skeletal muscle weakness and fatigability. It is caused by autoantibodies targeting proteins of the neuromuscular junction; ~85% of MG patients have autoantibodies against the muscle acetylcholine recep...

journal_title：Frontiers in neurology

authors： Lazaridis K,Tzartos SJ

更新日期：2020-11-30 00:00:00

abstract：:Introduction: Few studies have examined the motor, cognitive, and emotional factors involved in effective money management in persons with multiple sclerosis (MS). The aim of this study was to assess money management in persons MS and examine whether cognitive, motor, and emotional processes can predict money manageme...

journal_title：Frontiers in neurology

authors： Yael G,Nancy C,John D

更新日期：2019-10-23 00:00:00

abstract：:Although ~50% of patients with Parkinson's disease (PD) experience depression, treatment for this important and debilitating comorbidity is relatively understudied. Deep brain stimulation (DBS) has been increasingly utilized for the management of tremors in progressive PD. Several preliminary studies have shown the po...

journal_title：Frontiers in neurology

authors： Gökbayrak NS,Piryatinsky I,Gavett RA,Ahmed OJ

更新日期：2014-08-11 00:00:00

abstract：:Mutations of the voltage-gated sodium channel SCN8A have been identified in approximately 1% of nearly 1,500 children with early-infantile epileptic encephalopathies (EIEE) who have been tested by DNA sequencing. EIEE caused by mutation of SCN8A is designated EIEE13 (OMIM #614558). Affected children have seizure onset...

journal_title：Frontiers in neurology

authors： Wagnon JL,Meisler MH

更新日期：2015-05-15 00:00:00