Does Chronic Cannabis Use Impact Risky Decision-Making: An Examination of fMRI Activation and Effective Connectivity?

abstract：:The treatment of heroin addiction is a complex process involving changes in addictive behavior and brain functioning. The goal of this study was to explore the brain default mode network (DMN) functional connectivity using resting-state functional magnetic resonance imaging (rs-fMRI) and decision-making performance ba...

journal_title：Frontiers in psychiatry

authors： Kuo LW,Lin PS,Lin SY,Liu MF,Jan H,Lee HC,Wang SC

更新日期：2019-06-06 00:00:00

abstract：:Although there is extensive research indicating the vital role of functional emotion regulation (ER) in healthy psychological development, such research has neglected examination of adolescents. One potential reason for this neglect is the lack of valid ER instruments developed specifically for adolescents. Further, t...

journal_title：Frontiers in psychiatry

authors： Zhou Y,Daukantaitė D,Lundh LG,Wångby-Lundh M,Ryde A

更新日期：2020-05-28 00:00:00

abstract：:Objective: Despite the fact that autism spectrum disorder (ASD) is a common psychiatric diagnosis, knowledge about the special behavioral and neurobiological female phenotype is still scarce. The present study aimed to investigate neural correlates of empathy for physical and social pain and to assess the impact of eg...

journal_title：Frontiers in psychiatry

authors： Stroth S,Paye L,Kamp-Becker I,Wermter AK,Krach S,Paulus FM,Müller-Pinzler L

更新日期：2019-06-18 00:00:00

abstract：:Background: In Germany, people suffering from severe mental illness who have committed serious offenses and have considerably reduced or suspended criminal responsibility can be detained and treated in forensic psychiatric hospitals. In the German federal state of Baden-Wuerttemberg, all psychiatric hospitals includin...

journal_title：Frontiers in psychiatry

authors： Flammer E,Frank U,Steinert T

更新日期：2020-03-05 00:00:00

abstract：:Abnormalities in EEG gamma band oscillations (GBO, 30-80 Hz) serve as a prominent biomarker of schizophrenia (Sz), associated with positive, negative, and cognitive symptoms. Chronic, subanesthetic administration of antagonists of N-methyl-D-aspartate receptors (NMDAR), such as ketamine, elicits behavioral effects, an...

journal_title：Frontiers in psychiatry

authors： McNally JM,McCarley RW,Brown RE

更新日期：2013-09-17 00:00:00

abstract：:Objective: We previously found that chronic ketamine usages were associated with various psychotic and cognitive symptoms mimicking schizophrenia. The blockade of the NMDA receptor and subsequent nitric oxide synthase 1 (NOS1) dysfunction were found to be closely correlated with schizophrenia including NOS1 gene polym...

journal_title：Frontiers in psychiatry

authors： Chen J,Zhang M,Zhou C,Ding Y,Fan N,He H

更新日期：2020-12-23 00:00:00

abstract：Background:Recent meta-analyses reported placebo response rate in antidepressant trials to be stable since the 1970s. These meta-analyses however were limited in considering only linear time trends, assessed trial-level covariates based on single-model hypothesis testing only, and did not adjust for small-study effects...

journal_title：Frontiers in psychiatry

authors： Holper L

更新日期：2020-07-28 00:00:00

abstract：:The gut microbiota are known to have a profound influence on both mucosal and systemic immunity and are important for gastrointestinal (GI) function. In addition, new evidence shows that the microbiota significantly influence neurodevelopment and behavior. Immune dysfunction and GI distress are extremely common in ind...

journal_title：Frontiers in psychiatry

authors： Hughes HK,Ashwood P

更新日期：2018-11-26 00:00:00

abstract：Background:Depressive patients show less altruistic behavior. While, older adults present higher tendencies for altruism than younger adults. Depression and age are two of the influencing factors of altruism, kynurenine (KYN), and its metabolites. However, the characteristics of altruism in late-life depression (LLD) a...

journal_title：Frontiers in psychiatry

authors： Wu Y,Mai N,Weng X,Liang J,Ning Y

更新日期：2020-04-30 00:00:00

abstract：:The worldwide prevalence of sleep disorders is approximately 50%, with an even higher occurrence in a psychiatric population. Bipolar disorder (BD) is a severe mental illness characterized by shifts in mood and activity. The BD syndrome also involves heterogeneous symptomatology, including cognitive dysfunctions and i...

journal_title：Frontiers in psychiatry

authors： Steardo L Jr,de Filippis R,Carbone EA,Segura-Garcia C,Verkhratsky A,De Fazio P

更新日期：2019-07-18 00:00:00

abstract：:Recently, imaging biomarkers have gained importance for the characterization of patients with Alzheimer's disease; however, the relationship between regional biomarker expression and cognitive function remains unclear. In our study, we investigated associations between scores on CERAD neuropsychological assessment bat...

journal_title：Frontiers in psychiatry

authors： Hedderich DM,Drost R,Goldhardt O,Ortner M,Müller-Sarnowski F,Diehl-Schmid J,Zimmer C,Förstl H,Yakushev I,Jahn T,Grimmer T

更新日期：2020-08-13 00:00:00

abstract：:Molecular mechanisms in the brain are assumed to cause the symptoms and severity of neuropsychiatric disorders. This review concerns the elusive nature of relationships between the severity of depressive disorders and neuromolecular processes studied by positron emission tomography (PET). Recent PET studies of human d...

journal_title：Frontiers in psychiatry

authors： Smith DF,Jakobsen S

更新日期：2013-03-04 00:00:00

abstract：Introduction:Visual impairment (VI) is associated with a variety of comorbidities including physical and mental health in industrial countries. Our aim is to examine associations between self-reported impairment and depressive symptoms in the German population. Methods:The point prevalence of self-reported VI in Germa...

journal_title：Frontiers in psychiatry

authors： Schuster AK,Tesarz J,Rezapour J,Beutel ME,Bertram B,Pfeiffer N

更新日期：2018-04-09 00:00:00

abstract：:Background: The clinical and etiological heterogeneity of mood disorders impede identification of effective treatments for the individual patient. This highlights a need for early neuronal and behavioral biomarkers for treatment efficacy, which can provide a basis for more personalized treatments. The present systemat...

journal_title：Frontiers in psychiatry

authors： Seeberg I,Kjaerstad HL,Miskowiak KW

更新日期：2018-07-26 00:00:00

abstract：:Co-design, defined as collective creativity across the entire design process, can lead to the development of interventions that are more engaging, satisfying, and useful to potential users. However, using this methodology within the research arena requires a shift from traditional practice. Co-design of eHealth interv...

journal_title：Frontiers in psychiatry

authors： Thabrew H,Fleming T,Hetrick S,Merry S

更新日期：2018-10-18 00:00:00

abstract：:This study explored how different forms of reward-based decision-making are associated with pathological gambling (PG) among abstinent individuals with prior dependence on different classes of drugs. Participants had lifetime histories of either "pure" heroin dependence (n = 64), "pure" amphetamine dependence (n = 51)...

journal_title：Frontiers in psychiatry

authors： Wilson MJ,Vassileva J

更新日期：2018-06-05 00:00:00

abstract：:Investigation in posttraumatic stress disorder (PTSD) shows a negative association between patients' degrees of acceptance (the willingness to face unwanted private experiences while pursuing one's values and goals) and those of clinical symptom severity, suggesting that experiential acceptance is a protective factor ...

journal_title：Frontiers in psychiatry

authors： Jung WH,Kim NH

更新日期：2020-07-30 00:00:00

abstract：BACKGROUND:Females are twice as likely as males to experience depression. Recent findings indicate a relationship linking inflammation with depression. Whether the higher prevalence of depression in women is sex-specific or if inflammation contributes to a higher prevalence of depression in females is unclear. Thus, th...

journal_title：Frontiers in psychiatry

authors： Birur B,Amrock EM,Shelton RC,Li L

更新日期：2017-06-16 00:00:00

abstract：:Conscious attempts to regulate alcohol and drug use are often undermined by automatic attention and arousal processes that are activated in the context of salient cues. Response to these cues involves body and brain signals that are linked via dynamic feedback loops, yet no studies have targeted the cardiovascular sys...

journal_title：Frontiers in psychiatry

authors： Bates ME,Lesnewich LM,Uhouse SG,Gohel S,Buckman JF

更新日期：2019-09-05 00:00:00

abstract：BACKGROUND:Several lines of evidence implicate dysfunctional neuronal plasticity in the pathophysiology of schizophrenia (SCZ). Aberrant glutamatergic and gamma amino--butyric acid neurotransmission are thought to underlie core cognitive deficits and negative symptoms of SCZ. Non-invasive brain stimulation (NIBS) allow...

journal_title：Frontiers in psychiatry

authors： Bhandari A,Voineskos D,Daskalakis ZJ,Rajji TK,Blumberger DM

更新日期：2016-03-29 00:00:00

abstract：Background:Depression is a leading cause of disability worldwide and is a major contributor to the overall global burden of disease, but its etiology is poorly understood. It has been reported that a disrupted biological rhythm, in terms of a shortened light duration and total darkness, can cause depression-like behavi...

journal_title：Frontiers in psychiatry

authors： Hu H,Kang C,Hou X,Zhang Q,Meng Q,Jiang J,Hao W

更新日期：2020-04-08 00:00:00

abstract：:Introduction: Previous studies have indicated that changes in the concentration of glutamate and related metabolites may mediate the progression of addiction in patients with methamphetamine (MA) use disorders. In the present study, we utilized magnetic resonance spectroscopy (MRS) to investigate absolute glutamate co...

journal_title：Frontiers in psychiatry

authors： Yang W,Yang R,Luo J,He L,Liu J,Zhang J

更新日期：2018-08-31 00:00:00

abstract：:Socioeconomic status is a strong predictor of normative development and well-being in young people. It is well-known that growing up in a socioeconomically disadvantaged context may lead to negative outcomes, both in childhood and in adulthood. Early intervention and prevention programmes are crucial for building resi...

journal_title：Frontiers in psychiatry

authors： Kara B,Morris R,Brown A,Wigglesworth P,Kania J,Hart A,Mezes B,Cameron J,Eryigit-Madzwamuse S

更新日期：2021-01-14 00:00:00

abstract：:The progress of developing effective interventions against psychiatric disorders has been limited due to a lack of understanding of the underlying cellular and functional mechanisms. Recent research findings focused on exploring novel causes of psychiatric disorders have highlighted the importance of the axonal initia...

journal_title：Frontiers in psychiatry

authors： Hsu WC,Nilsson CL,Laezza F

更新日期：2014-08-21 00:00:00

abstract：:Social sharing capacities have attracted attention from a number of fields of social cognition and have been variously defined and analyzed in numerous studies. Social sharing consists in the subjective awareness that aspects of the self's experience are held in common with other individuals. The definition of social ...

journal_title：Frontiers in psychiatry

authors： Colle L,Pellecchia G,Moroni F,Carcione A,Nicolò G,Semerari A,Procacci M

更新日期：2017-12-04 00:00:00

abstract：:Objectives: While evidence that episodes of mania in bipolar I are associated with changes in bioenergetic and regional cerebral blood flow (rCBF) and cerebral blood flow velocity (rCBFV), both the regions and the extent of these changes have not yet been defined. Therefore, we determined the pattern of regional cereb...

journal_title：Frontiers in psychiatry

authors： Wang Y,Liu X,Li P,Zhou H,Yang L,Zheng L,Xie P,Li L,Liao DJ,Liu Q,Fang D

更新日期：2018-07-04 00:00:00

abstract：Background:Discharge from acute mental health services has long been associated with mortality, risk, and related adverse outcomes for patients. Many of the interventions that currently aim to reduce adverse outcomes focus on a single group of healthcare professionals within a single healthcare setting. A recent system...

journal_title：Frontiers in psychiatry

authors： Tyler N,Wright N,Grundy A,Gregoriou K,Campbell S,Waring J

更新日期：2020-04-21 00:00:00

abstract：:Background: More information is needed about the efficacy and safety of long-term baclofen in the treatment of alcohol use disorders. The objective of this study was to assess the effect of treatment with tailored-dose baclofen on alcohol consumption in patients with alcohol use disorders followed for 3 years after fi...

journal_title：Frontiers in psychiatry

authors： Pinot J,Rigal L,Granger B,Sidorkiewicz S,Jaury P

更新日期：2018-10-08 00:00:00

abstract：:Previous work from our group and others utilizing animal models have demonstrated long-lasting structural and functional alterations in the meso-cortico-striatal dopamine pathway following prenatal cocaine (PCOC) treatment. We have shown that PCOC treatment results in augmented D1-induced cyclic AMP (cAMP) and cocaine...

journal_title：Frontiers in psychiatry

authors： Tropea TF,Kabir ZD,Kaur G,Rajadhyaksha AM,Kosofsky BE

更新日期：2011-12-07 00:00:00

abstract：:Refugee children share a large number of pre-, peri-, and post-migration risk factors, which make them vulnerable for developing mental health concerns. Within the last few years, a large number of families with young children have sought refuge in Germany. However, children's mental health status in Germany is mostly...

journal_title：Frontiers in psychiatry

authors： Buchmüller T,Lembcke H,Busch J,Kumsta R,Leyendecker B

更新日期：2018-05-25 00:00:00