Progressive Cerebral Small Vessel Disease Caused by an Autoimmune Response to Intravesical Bacille-Calmette-Guérin Treatment.

abstract：:Purpose: The use of optical coherence tomography (OCT) of the retina to detect inner retinal degeneration is being investigated as a potential biomarker for mild cognitive impairment (MCI) and Alzheimer's disease (AD), and an overwhelming body of evidence indicates that discovery of disease-modifying treatments for AD...

journal_title：Frontiers in neurology

authors： Mejia-Vergara AJ,Restrepo-Jimenez P,Pelak VS

更新日期：2020-10-16 00:00:00

abstract：:Approaches to furthering our understanding of the bioeffects, behavioral changes, and treatment options following exposure to blast are a worldwide priority. Of particular need is a more concerted effort to employ animal models to determine possible sex differences, which have been reported in the clinical literature....

journal_title：Frontiers in neurology

authors： McCabe JT,Tucker LB

更新日期：2020-09-30 00:00:00

abstract：:[This corrects the article DOI: 10.3389/fneur.2020.563609.]. ...

journal_title：Frontiers in neurology

authors： Zhang J,Meng Q,Zhong J,Zhang M,Qin X,Ni X,Ma J,He Y,Zeng D,Lan D

更新日期：2020-11-12 00:00:00

abstract：:Background/Aims: High intracranial pressure (ICP) is associated with changes in peripapillary Bruch's membrane (pBM) shape on optical coherence tomography (OCT) images of the optic nerve head. It is not known if image acquisition pattern and analysis method impact this association. Materials and Methods: Cross section...

journal_title：Frontiers in neurology

authors： Malhotra K,Patel MD,Shirazi Z,Moss HE

更新日期：2018-12-21 00:00:00

abstract：:Background: The relationship between varicella-zoster virus (VZV)-associated myelitis and aquaporin-4 immunoglobulin-G (AQP4-IgG) remains unknown. Case Report: We report a case of acute radiculomyelitis with longitudinal extensive hyperintensity signals traversing the brainstem until the upper thoracic cord in a 55-ye...

journal_title：Frontiers in neurology

authors： Eguchi H,Takeshige H,Nakajima S,Kanou M,Nakajima A,Fuse A,Fukae J,Miwa H,Shimo Y

更新日期：2020-11-23 00:00:00

abstract：:The vestibular system plays a crucial role in maintaining postural balance. Unilateral vestibular lesions result in a typical syndrome characterized by postural imbalance, altered locomotor patterns and gaze stabilization, as well as cognitive and neurovegetative disorders. One of the main difficulties encountered in ...

journal_title：Frontiers in neurology

authors： Marouane E,Rastoldo G,El Mahmoudi N,Péricat D,Chabbert C,Artzner V,Tighilet B

更新日期：2020-05-29 00:00:00

abstract：:A decrease in glutamate in the medial prefrontal cortex (mPFC) has been extensively found in animal models of chronic pain. Given that the mPFC is implicated in emotional appraisal, cognition and extinction of fear, could a potential decrease in glutamate be associated with increased pessimistic thinking, fear and wor...

journal_title：Frontiers in neurology

authors： Naylor B,Hesam-Shariati N,McAuley JH,Boag S,Newton-John T,Rae CD,Gustin SM

更新日期：2019-12-03 00:00:00

abstract：:Despite extensive research, the functions of the basal ganglia (BG) in movement control have not been fully understood. Eye movements, particularly saccades, are convenient indicators of BG function. Here, we review the main oculomotor findings reported in Parkinson's disease (PD) and genetic parkinsonian syndromes. P...

journal_title：Frontiers in neurology

authors： Pretegiani E,Optican LM

更新日期：2017-11-09 00:00:00

abstract：OBJECTIVE:Morphological changes of recent small subcortical infarcts are not well defined. The purpose of the present study was to describe the MRI characteristics of the evolution for this stroke subtype. METHODS:We conducted a retrospective review of patients diagnosed with definite supratentorial recent small subco...

journal_title：Frontiers in neurology

authors： Okazaki S,Hornberger E,Griebe M,Gass A,Hennerici MG,Szabo K

更新日期：2015-05-26 00:00:00

abstract：:Sleep disturbances such as excessive daytime sleepiness, central and obstructive sleep apneas, restless legs syndrome, and rapid eye movement sleep dysregulation are prominent in patients with myotonic dystrophy type 1 (DM1). Mild intellectual deficits presented in many patients with DM1. In addition, psychosocial iss...

journal_title：Frontiers in neurology

authors： Urata Y,Nakamura M,Shiokawa N,Yasuniwa A,Takamori N,Imamura K,Hayashi T,Ishizuka T,Kasugai M,Sano A

更新日期：2020-02-14 00:00:00

abstract：:Purpose: Cardiac [123I]metaiodobenzylguanidine scintigraphy (123I-MIBG), reflecting postganglionic cardiac autonomic denervation, is proposed for early detection of Parkinson's disease (PD; reduced tracer uptake) and separation from Multiple System Atrophy (MSA; preserved tracer uptake). However, several recent studie...

journal_title：Frontiers in neurology

authors： Skowronek C,Zange L,Lipp A

更新日期：2019-02-26 00:00:00

abstract：:The development of wearable devices has increase interest in the use of ambulatory methods to detect sleep disorders more objectively than those permitted by subjective scales evaluating sleep quality, while subjects maintain their usual lifestyle. This study aims to validate an ambulatory circadian monitoring (ACM) d...

journal_title：Frontiers in neurology

authors： Madrid-Navarro CJ,Puertas Cuesta FJ,Escamilla-Sevilla F,Campos M,Ruiz Abellán F,Rol MA,Madrid JA

更新日期：2019-04-11 00:00:00

abstract：:Background: Giant vertebrobasilar aneurysms (GVBAs) have an unfavorable natural history if left untreated and often pose a sizeable challenge to endovascular treatment. The aim of this study was to analyze the angiographic and clinical outcomes of GVBAs treated by various endovascular procedures. Methods: Between Janu...

journal_title：Frontiers in neurology

authors： Li M,Liang H,Wang J

更新日期：2020-08-11 00:00:00

abstract：:Aims: To investigate the relationship between clinical and imaging features of stroke patients with patent foramen ovale (PFO) and those with spontaneous intracranial artery dissection (SIAD). Materials and methods: We retrospectively examined both clinical and imaging results of 40 stroke patients with PFO and 29 wit...

journal_title：Frontiers in neurology

authors： Huang Y,Cheng Y,Shao B,Zhou X,Liang H,Zhuang J,Bi Y

更新日期：2019-04-24 00:00:00

abstract：:Background: Phosphatidylinositol binding clathrin assembly protein (PICALM) rs541458 C allele has been identified and validated to be associated with a reduction of Alzheimer's disease (AD) risk. Nevertheless, the exact mechanisms through which the variant exert its disease-relevant association remain to be elucidated...

journal_title：Frontiers in neurology

authors： Zhuang L,Liu X,Shi Y,Liu X,Luo B

更新日期：2019-05-08 00:00:00

abstract：:Background: The causal relationship between serum lipid levels and the risk of Parkinson's disease (PD) remains largely uncertain. We summarized the existing controversial evidence on this topic. Methods: We searched the electronic databases for observational studies from January 1988 to March 2020. We applied random-...

journal_title：Frontiers in neurology

authors： Jiang Z,Xu X,Gu X,Ou R,Luo X,Shang H,Song W

更新日期：2020-06-26 00:00:00

abstract：:Ischemic stroke is one of the leading causes for death and disability worldwide. In patients with large space-occupying infarction, the subsequent edema complicated by transtentorial herniation poses a lethal threat. Especially in patients with malignant middle cerebral artery infarction, brain swelling secondary to t...

journal_title：Frontiers in neurology

authors： Pallesen LP,Barlinn K,Puetz V

更新日期：2019-01-09 00:00:00

abstract：:The relationship between circadian rhythm and epilepsy has been recognized for decades. Yet many questions underlying the complex mechanisms of their interaction remain elusive. A better understanding on this topic allows the development of accurate seizure-detection algorithm and alternative precise therapeutic strat...

journal_title：Frontiers in neurology

authors： Xu C,Yu J,Ruan Y,Wang Y,Chen Z

更新日期：2020-07-24 00:00:00

abstract：:Background and objective: Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is an inherited systemic arteriopathy, the classic feature of which is small vessel lesions. Studies on intracranial large arteries in CADASIL are not common. We aim to evaluate intracranial l...

journal_title：Frontiers in neurology

authors： Zhang C,Li W,Li S,Niu S,Wang X,Yu X,Zhang Z

更新日期：2020-08-18 00:00:00

abstract：AIMS:To construct and validate a short scale for the assessment of the severity of visual height intolerance (vHI) and acrophobia. METHODS:The questionnaire was developed from two earlier representative epidemiological studies (n = 5,529). Items were applied in a telephone survey of a representative population-based s...

journal_title：Frontiers in neurology

authors： Huppert D,Grill E,Brandt T

更新日期：2017-06-01 00:00:00

abstract：:Parkinson's disease dementia (PDD) and dementia with Lewy bodies (DLB) are common causes of dementia worldwide. Although considered separate entities based on the relative temporal onset of motor symptoms vs. diagnosis of dementia, it is unknown if these diseases truly have distinct cognitive profiles. We hypothesized...

journal_title：Frontiers in neurology

authors： Aldridge GM,Birnschein A,Denburg NL,Narayanan NS

更新日期：2018-03-12 00:00:00

abstract：Objective:Vestibular signals are involved in higher cortical functions like spatial orientation and its disorders. Vestibular dysfunction contributes, for example, to spatial neglect which can be transiently improved by caloric stimulation. The exact roles and mechanisms of the vestibular and visual systems for the rec...

journal_title：Frontiers in neurology

authors： Conrad J,Boegle R,Ertl M,Brandt T,Dieterich M

更新日期：2018-03-02 00:00:00

abstract：:Recent advances in wearable sensor technology and machine learning (ML) have allowed for the seamless and objective study of human motion in clinical applications, including Parkinson's disease, and stroke. Using ML to identify salient patterns in sensor data has the potential for widespread application in neurologica...

journal_title：Frontiers in neurology

authors： Parnandi A,Uddin J,Nilsen DM,Schambra HM

更新日期：2019-09-18 00:00:00

abstract：:Over the past decade, it was found that relatively simple sphingolipids, such as ceramide, sphingosine, sphingosine-1-phosphate, and glucosylceramide play important roles in neuronal functions by regulating rates of neuronal growth and differentiation. Homeostasis of membrane sphingolipids in neurons and myelin is ess...

journal_title：Frontiers in neurology

authors： Alessenko AV,Albi E

更新日期：2020-05-21 00:00:00

abstract：:X-linked adrenoleukodystrophy (X-ALD) is a rare neurological disorder with a highly complex clinical presentation. Adrenal function, spinal cord, peripheral nerves, and cerebral white matter are commonly affected in adult-onset male patients. Here, we report a family with unusual presentation of X-ALD. The 19-year-old...

journal_title：Frontiers in neurology

authors： Chen Y,Zhang J,Wang J,Wang K

更新日期：2018-04-23 00:00:00

abstract：:[This corrects the article DOI: 10.3389/fneur.2018.00184.]. ...

journal_title：Frontiers in neurology

authors： Janca R,Krsek P,Jezdik P,Cmejla R,Tomasek M,Komarek V,Marusic P,Jiruska P

更新日期：2019-06-14 00:00:00

abstract：:Primary progressive aphasia (PPA) is a neurodegenerative disease characterized by declining language ability. However, the difficulty in defining the central clinical features in its earliest stage and establishing the dynamics of its progression has led to controversy. We report a 71-year-old man with Han language su...

journal_title：Frontiers in neurology

authors： Liu X,He F,Chen Z,Liu P,Peng G

更新日期：2018-02-16 00:00:00

abstract：:Background: Measuring cognitive functioning is common in traumatic brain injury (TBI) research, but no universally accepted method for combining several neuropsychological test scores into composite, or summary, scores exists. This study examined several possible composite scores for the test battery used in the large...

journal_title：Frontiers in neurology

authors： Stenberg J,Karr JE,Terry DP,Saksvik SB,Vik A,Skandsen T,Silverberg ND,Iverson GL

更新日期：2020-07-17 00:00:00

abstract：BACKGROUND:An estimated 30-50% of essential tremor (ET) diagnoses are incorrect, and the true diagnosis in those patients is often Parkinson's disease (PD) or other tremor disorders. There are general statements about the tremor in these ET and PD, but published data on the more subtle characteristics of tremor are sur...

journal_title：Frontiers in neurology

authors： Sternberg EJ,Alcalay RN,Levy OA,Louis ED

更新日期：2013-05-10 00:00:00

abstract：:Background: Intracranial carotid artery calcification (ICAC) on computed tomography (CT) is a marker of atherosclerosis and an independent predictor of vascular events including stroke. While vitamin K antagonists (VKAs) are used to prevent embolic stroke, they have been shown to increase levels of both coronary and e...

journal_title：Frontiers in neurology

authors： Peeters MTJ,Houben R,Postma AA,van Oostenbrugge RJ,Schurgers LJ,Staals J

更新日期：2019-12-20 00:00:00