Sex-Specific Differences in Rodents Following a Single Primary Blast Exposure: Focus on the Monoamine and Galanin Systems.

abstract：:α-synuclein is involved in the pathogenesis of multiple system atrophy (MSA) and can be regulated by peripheral immune activation (PIA). We aimed to clarify the correlations between PIA and the prevalence of MSA and to analyze the role of PIA in the progression of the disease. A total of 321 patients with probable MSA...

journal_title：Frontiers in neurology

authors： Cao B,Chen X,Zhang L,Wei Q,Liu H,Feng W,Chen Y,Shang H

更新日期：2020-07-07 00:00:00

abstract：:Glaucoma is a multifactorial syndrome in which the development of pro-apoptotic signals are the causes for retinal ganglion cell (RGC) loss. Most of the research progress in the glaucoma field have been based on experimentally inducible glaucoma animal models, which provided results about RGC loss after either the cra...

journal_title：Frontiers in neurology

authors： Tirendi S,Saccà SC,Vernazza S,Traverso C,Bassi AM,Izzotti A

更新日期：2020-12-01 00:00:00

abstract：:Mutations of the voltage-gated sodium channel SCN8A have been identified in approximately 1% of nearly 1,500 children with early-infantile epileptic encephalopathies (EIEE) who have been tested by DNA sequencing. EIEE caused by mutation of SCN8A is designated EIEE13 (OMIM #614558). Affected children have seizure onset...

journal_title：Frontiers in neurology

authors： Wagnon JL,Meisler MH

更新日期：2015-05-15 00:00:00

abstract：:Epilepsy is a neurological disorder in which, in many cases, there is poor pharmacological control of seizures. Nevertheless, it may respond beneficially to alternative treatments such as dietary therapy, like the ketogenic diet or caloric restriction. One of the mechanisms of these diets is to produce a hyperpolariza...

journal_title：Frontiers in neurology

authors： Rubio C,Luna R,Rosiles A,Rubio-Osornio M

更新日期：2020-11-05 00:00:00

abstract：:Background: Transcranial direct current stimulation (tDCS) and therapy-based virtual reality (VR) have been investigated separately. They have shown promise as efficient and engaging new tools in the neurological rehabilitation of individuals with cerebral palsy (CP). However, the recent literature encourages investig...

journal_title：Frontiers in neurology

authors： da Silva TD,Fontes AMGG,de Oliveira-Furlan BS,Roque TT,Lima AII,de Souza BMM,Alberissi CAO,Silveira AC,de Moraes ÍAP,Collett J,Silva RP,Airoldi MJ,Ribeiro-Papa DC,Dawes H,Monteiro CBM

更新日期：2020-09-02 00:00:00

abstract：:Previous consensus statements on sports concussion have highlighted the importance of Attention Deficit Hyperactivity Disorder (ADHD) and loss of consciousness (LOC) as risk factors related to concussion management. The present study investigated how self-reported history of either ADHD diagnosis or history of previou...

journal_title：Frontiers in neurology

authors： Kaye S,Sundman MH,Hall EE,Williams E,Patel K,Ketcham CJ

更新日期：2019-04-24 00:00:00

abstract：:Extracellular vesicles (EVs) are involved in the development and progression of neurodegenerative diseases, including Alzheimer's and Parkinson's disease. Moreover, EVs have the capacity to modify the physiology of neuronal circuits by transferring proteins, RNA, lipids, and metabolites. The proteomic characterization...

journal_title：Frontiers in neurology

authors： Quiroz-Baez R,Hernández-Ortega K,Martínez-Martínez E

更新日期：2020-12-11 00:00:00

abstract：:We describe the case of one patient with pure sporadic hemiplegic migraine (SHM) with a novel ATP1A2 gene variant and a large patent foramen ovale (PFO) with atrial septal aneurysm. In hemiplegic migraine (HM), the relationship between incomplete penetrance, environmental triggers, and phenotypic expression is underde...

journal_title：Frontiers in neurology

authors： Perrotta A,Gambardella S,Ambrosini A,Anastasio MG,Albano V,Fornai F,Pierelli F

更新日期：2018-05-17 00:00:00

abstract：:Sudden unexpected death in epilepsy (SUDEP) is the most common cause of premature mortality in individuals with epilepsy. Acute and adaptive changes in heart rhythm in epilepsy implicate cardiac dysfunction as a potential pathogenic mechanism in SUDEP. Furthermore, variants in genes associated with Long QT syndrome (L...

journal_title：Frontiers in neurology

authors： Bleakley LE,Soh MS,Bagnall RD,Sadleir LG,Gooley S,Semsarian C,Scheffer IE,Berkovic SF,Reid CA

更新日期：2020-09-08 00:00:00

abstract：:Background: MOH can be diagnosed in subjects with headache occurring 15 days/month in association with a regular medication overuse, but its existence is not universally accepted. ICHD-3 redefined criteria for MOH, removing the criterion associating drug suspension with headache course. The aim of our study was to com...

journal_title：Frontiers in neurology

authors： Moavero R,Stornelli M,Papetti L,Ursitti F,Ferilli MAN,Balestri M,Sforza G,Tarantino S,Vigevano F,Valeriani M

更新日期：2020-08-19 00:00:00

abstract：:With respect to photoreceptor function, it is well known that electroretinogram (ERG) amplitudes decrease with age, but to our knowledge, studies describing age-related changes in the pupil light response (PLR) of mice are lacking. This study recorded the PLR and ERG in C57BL/6 and Sv129S6 wild-type mice at three diff...

journal_title：Frontiers in neurology

authors： Kircher N,Crippa SV,Martin C,Kawasaki A,Kostic C

更新日期：2019-02-04 00:00:00

abstract：OBJECTIVE:To provide a systematic review of the clinical and radiological features of lesion-induced central positional nystagmus (CPN) and identify salient characteristics that differentiate central from peripheral positional nystagmus (PN). METHODS:Systematic literature search according to the preferred reporting it...

journal_title：Frontiers in neurology

authors： Macdonald NK,Kaski D,Saman Y,Al-Shaikh Sulaiman A,Anwer A,Bamiou DE

更新日期：2017-04-20 00:00:00

abstract：:Objective: To report a rare case of brainstem encephalitis with low-titer acetylcholine receptor antibodies mimicking myasthenia gravis. Methods: The patient was investigated with repeated brain MRI, CSF examination, repetitive nerve stimulation, thoracic CT, and serologic screening. Our patient passed away and finall...

journal_title：Frontiers in neurology

authors： Ayzenberg I,Ellrichmann G,Schroeder C,Tönges L,Klasing A,Pappa V,Brück W,Gold R

更新日期：2019-08-02 00:00:00

abstract：:Tumor necrosis factor-alpha (TNF-α) is a proinflammatory cytokine that plays a prominent role in the nervous system, mediating a range of physiologic and pathologic functions. In the auditory system, elevated levels of TNF-α have been implicated in several types of sensorineural hearing loss, including sensorineural h...

journal_title：Frontiers in neurology

authors： Katsumi S,Sahin MI,Lewis RM,Iyer JS,Landegger LD,Stankovic KM

更新日期：2020-02-10 00:00:00

abstract：:Introduction: Although patients with Parkinson's disease (PD) often suffer from oropharyngeal dysphagia, knowledge about the underlying pathophysiological mechanisms is limited. Substance P (SP) is a localization-independent neurotransmitter of the entire nervous system. Reduced levels of SP were found in saliva of pa...

journal_title：Frontiers in neurology

authors： Schröder JB,Marian T,Claus I,Muhle P,Pawlowski M,Wiendl H,Suntrup-Krueger S,Meuth SG,Dziewas R,Ruck T,Warnecke T

更新日期：2019-04-16 00:00:00

abstract：:Objective: Hemorrhagic transformation (HT) in ischemic moyamoya disease (MMD), reasonably defined as hemorrhage events in patients with ischemic onset manifestation, leads to a poor outcome. This study aims to reveal factors associated with HT in patients with ischemic onset manifestation and to assess the outcome of ...

journal_title：Frontiers in neurology

authors： Lu J,Li Z,Zhao Y,Chen X,Shi G,Zhao J

更新日期：2020-06-25 00:00:00

abstract：:In task-specific focal hand dystonia (tspFHD), the temporal dynamics of cortical activity in the motor system and how these processes are related to impairments in sensory and motor function are poorly understood. Here, we use time-frequency reconstructions of magnetoencephalographic (MEG) data to elaborate the tempor...

journal_title：Frontiers in neurology

authors： Hinkley LB,Dolberg R,Honma S,Findlay A,Byl NN,Nagarajan SS

更新日期：2012-11-28 00:00:00

abstract：:Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy (BMD) are X-linked recessive neuromuscular disorders caused by mutations in DMD. A high-quality database of DMD/BMD is essential not only for clinical practice but also for fundamental research. Here, we aimed to build the largest Chinese national dystrop...

journal_title：Frontiers in neurology

authors： Tong YR,Geng C,Guan YZ,Zhao YH,Ren HT,Yao FX,Ling C,Wang DC,Chen L,Cui LY,Zhang SY,Dai Y

更新日期：2020-09-30 00:00:00

abstract：:Objectives: Patient-reported outcomes gain importance for the assessment of auditory abilities in cochlear implant users and for the evaluation of auditory rehabilitation. Aims of the study were to explore the interrelation of self-reported improvements in auditory ability with improvements in speech comprehension and...

journal_title：Frontiers in neurology

authors： Wallhäusser-Franke E,Balkenhol T,Hetjens S,Rotter N,Servais JJ

更新日期：2018-09-10 00:00:00

abstract：:Expansion of the neural progenitor pool in the developing cerebral cortex is crucial for controlling brain size, since proliferation defects have been associated with the pathogenesis of microcephaly in humans. Cell cycle regulators play important roles in proliferation of neural progenitors. Here, we show that the cy...

journal_title：Frontiers in neurology

authors： Chen Y,Bian S,Zhang J,Zhang H,Tang B,Sun T

更新日期：2014-07-18 00:00:00

abstract：:The aim of this study was to present a model that uses multi-parametric quantitative MRI to estimate the presence of myelin and edema in the brain. The model relates simultaneous measurement of R1 and R2 relaxation rates and proton density to four partial volume compartments, consisting of myelin partial volume, cellu...

journal_title：Frontiers in neurology

authors： Warntjes M,Engström M,Tisell A,Lundberg P

更新日期：2016-02-17 00:00:00

abstract：:Ankylosing spondylitis (AS) mainly affects the axial skeleton and is an important factor leading to chronic lower back pain in young individuals. However, few studies have explored alterations of brain gray matter volume in AS patients. The purpose of the present study was to describe brain gray matter abnormalities a...

journal_title：Frontiers in neurology

authors： Hua K,Wang P,Lan Z,Li M,Zhao W,Wang T,Li S,Ma X,Li C,Fu S,Yin Y,Liu P,Fang J,Li T,Jiang G

更新日期：2020-11-30 00:00:00

abstract：:Background: Listeria rhombencephalitis, infection of the brainstem with Listeria monocytogenes, occurs mainly in humans and farmed ruminants and is associated with high fatality rates. Small ruminants (goats and sheep) are a large animal model due to neuropathological similarities. The purpose of this study was to def...

journal_title：Frontiers in neurology

authors： Precht C,Vermathen P,Henke D,Staudacher A,Lauper J,Seuberlich T,Oevermann A,Schweizer-Gorgas D

更新日期：2020-12-14 00:00:00

abstract：:This review begins with the history of the events starting with the death of Libby Zion that lead to the Bell Commission, that the studied her death and made recommendations for improvement that were codified into law in New York state as the 405 law that the ACGME essentially adopted in putting a cap on work hours an...

journal_title：Frontiers in neurology

authors： Kramer M

更新日期：2010-10-20 00:00:00

abstract：:Background: The causal relationship between serum lipid levels and the risk of Parkinson's disease (PD) remains largely uncertain. We summarized the existing controversial evidence on this topic. Methods: We searched the electronic databases for observational studies from January 1988 to March 2020. We applied random-...

journal_title：Frontiers in neurology

authors： Jiang Z,Xu X,Gu X,Ou R,Luo X,Shang H,Song W

更新日期：2020-06-26 00:00:00

abstract：:The aim of the present study was to evaluate the correlation between the end of an Oxford sleep resistance (OSLER) test session and a neurophysiological marker of sleep onset in Parkinson's disease (PD) patients. Single center study was conducted in PD patients with excessive daytime sleepiness [Epworth sleepiness sca...

journal_title：Frontiers in neurology

authors： Neutel D,Peralta R,Pires J,Bentes C,Ferreira JJ

更新日期：2015-09-24 00:00:00

abstract：:Neuropathological features in Alzheimer's disease (AD) are amyloid β (Aβ) deposits and neurofibrillary changes. AD is characterized by memory impairment and cognitive dysfunction, with some reports associating these impairments with hyperexcitability caused by Aβ in the medial temporal lobe. Epileptic seizures are kno...

journal_title：Frontiers in neurology

authors： Hirokawa Y,Fujimoto A,Ichikawa N,Sato K,Tanaka T,Enoki H,Otsuki Y,Okanishi T

更新日期：2019-06-12 00:00:00

abstract：BACKGROUND:Amnestic mild cognitive impairment (aMCI) is considered to be the transitional stage between healthy aging and Alzheimer's disease (AD). Moreover, aMCI individuals with additional impairment in one or more non-memory cognitive domains are at higher risk of conversion to AD. Hence accurate identification of t...

journal_title：Frontiers in neurology

authors： Raamana PR,Wen W,Kochan NA,Brodaty H,Sachdev PS,Wang L,Beg MF

更新日期：2014-05-21 00:00:00

abstract：:Given the increasing use of regenerative free muscle flaps for various reconstructive procedures and neuroprosthetic applications, there is great interest and value in their enhanced regeneration, revascularization, and reinnervation for improved functional recovery. Here, we implant polyimide-based mircroelectrodes o...

journal_title：Frontiers in neurology

authors： Srinivasan S,Vyas K,McAvoy M,Calvaresi P,Khan OF,Langer R,Anderson DG,Herr H

更新日期：2019-03-22 00:00:00

abstract：:Many neurodegenerative disorders are associated with rapid eye movement sleep (REMS) loss; however, the mechanism was unknown. As REMS loss elevates noradrenaline (NA) level in the brain as well as induces neuronal apoptosis and degeneration, in this study, we have delineated the intracellular molecular pathway involv...

journal_title：Frontiers in neurology

authors： Somarajan BI,Khanday MA,Mallick BN

更新日期：2016-03-07 00:00:00