Abstract:
BACKGROUND:Squamous cell carcinoma antigen (SCCA) is regarded as a specific indicator of epithelial malignancies and is widely used in the diagnosis of squamous cell carcinoma (SCC). However, the expression of SCCA in gastric adenocarcinoma has not been studied in detail. CASE SUMMARY:A 52-year-old man was admitted to our hospital for a 2.5 cm × 2.5 cm ulcer at the antrum-body junction with dull pain and fullness in the upper abdomen for 2 mo. His pre-surgery serological testing results showed 0.51 ng/mL SCCA (reference interval, < 1.5 ng/mL) and 9.9 ng/mL carcinoembryonic antigen (reference range, < 4.7 ng/mL). He underwent radical distal gastrectomy and Roux-en Y anastomosis and was diagnosed with poorly differentiated mucinous adenocarcinoma (Lauren classification: Diffuse) by pathological examination of the resected lesion. Immunohistochemistry showed that SCCA was highly expressed in the cytoplasm of cancer cells. After surgery, the patient received an S-1 adjuvant chemotherapy regimen for six cycles containing tegafur, gimeracil, and oteracil potassium. He showed no sign of recurrence or metastasis within 24-mo follow-up. CONCLUSION:This is a frontal report of SCCA overexpression in poorly differentiated adenocarcinoma of the stomach.
journal_name
World J Clin Casesjournal_title
World journal of clinical casesauthors
Wang L,Huang L,Xi L,Zhang SC,Zhang JXdoi
10.12998/wjcc.v8.i19.4572subject
Has Abstractpub_date
2020-10-06 00:00:00pages
4572-4578issue
19issn
2307-8960journal_volume
8pub_type
abstract:BACKGROUND:Aplasia cutis congenita (ACC) in newborns is a condition in which congenital defects or hypoplasia is present in part of the epidermis, dermis and even subcutaneous tissue (including muscle and bones). First reported by Cordon in 1767, ACC is a rare disease with a low incidence of 1/100000 to 3/10000. Curren...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v7.i17.2611
更新日期:2019-09-06 00:00:00
abstract:BACKGROUND:In previous studies, celiomesenteric trunk (CMT) was narrowly defined as a hepato-gastro-spleno-mesenteric (HGSM) trunk, but other possible types were ignored. With the widespread use of multidetector computed tomography (MDCT) angiography, it is easy to collect a large sampling of data on arterial anatomy o...
journal_title:World journal of clinical cases
pub_type: 杂志文章
doi:10.12998/wjcc.v7.i23.3980
更新日期:2019-12-06 00:00:00
abstract:BACKGROUND:In most cases, it is not difficult to differentiate common bile duct (CBD) stone from Ascaris infection because they are different disease entities and have different imaging findings. The two diseases usually demonstrate unique characteristic findings on computed tomography or magnetic resonance cholangiopa...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v8.i19.4499
更新日期:2020-10-06 00:00:00
abstract::We report the case of a 56-year-old woman with pancreatic adenocarcinoma (PA) discovered during an episode of febrile jaundice. A computed tomography (CT) scan showed a mass in the head of the pancreas with circumferential infiltration of the superior mesenteric vein (SMV) and dilatation of the biliary and pancreatic ...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v6.i8.214
更新日期:2018-08-16 00:00:00
abstract::In colorectal cancer (CRC), liver metastasis remains a major contributor to the cause of cancer-related death. Putative biomarkers, therapeutic efficacy, and drug insensitivity still pose clinical challenges for metastatic CRC patients. Interestingly, previous studies indicated that tumor cells in CRC did not metastas...
journal_title:World journal of clinical cases
pub_type: 杂志文章,评审
doi:10.12998/wjcc.v8.i11.2111
更新日期:2020-06-06 00:00:00
abstract:BACKGROUND:Type A insulin resistance syndrome is a rare disorder caused by mutations in the gene encoding the insulin receptor. Its coexistence with ovarian serous papillary cystadenofibroma is even rarer. CASE SUMMARY:A 14-year-old girl developed type A insulin resistance syndrome and showed high fasting insulin, glu...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v8.i15.3334
更新日期:2020-08-06 00:00:00
abstract:BACKGROUND:Micronodular thymic tumors with lymphoid stroma include micronodular thymoma with lymphoid stroma (MNT) and micronodular thymic carcinoma with lymphoid hyperplasia (MNC), whose micromorphological features are lymphoid stromal hyperplasia and nodular arrangement of tumor epithelial cells. This type of tumor i...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v7.i23.4063
更新日期:2019-12-06 00:00:00
abstract:BACKGROUND:Acute kidney injury (AKI) after liver transplantation (LT) is a frequent and multifactorial event related to increased morbidity and mortality. Risk factors for AKI after LT still need to be clarified. AIM:To identify the predictors of acute kidney injury after liver transplantation. METHODS:The frequency ...
journal_title:World journal of clinical cases
pub_type: 杂志文章
doi:10.12998/wjcc.v8.i18.4034
更新日期:2020-09-26 00:00:00
abstract:BACKGROUND:Idiopathic adulthood ductopenia (IAD) is a chronic cholestatic liver disease of unknown etiology that usually presents as unexplained jaundice. It is characterized by adult onset, lack of autoantibodies, inflammatory bowel disease and loss of interlobular bile ducts. CASE SUMMARY:This case presents a 27-yea...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v8.i24.6524
更新日期:2020-12-26 00:00:00
abstract:BACKGROUND:Underwater endoscopic mucosal resection (UEMR) of colorectal lesions is emerging as an alternative method to conventional endoscopic mucosal resection (EMR); however, it is still controversial whether there is a difference in the effectiveness between UEMR and EMR. AIM:To evaluate the effectiveness and safe...
journal_title:World journal of clinical cases
pub_type: 杂志文章
doi:10.12998/wjcc.v8.i20.4826
更新日期:2020-10-26 00:00:00
abstract:BACKGROUND:Fetal akinesia deformation sequence (FADS) is a broad spectrum disorder with absent fetal movements as the unifying feature. The etiology of FADS is heterogeneous and mostly still unknown. A prenatal diagnosis of FADS relies on clinical features obtained by ultrasound and fetal muscle pathology. However, the...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v7.i21.3655
更新日期:2019-11-06 00:00:00
abstract:BACKGROUND:Sebaceous lymphadenoma is a benign tumor that occurs rarely in the salivary glands, most commonly in the parotid glands or periparotid lymph nodes, and even more rarely undergoes malignant transformation into a sebaceous lymphadenocarcinoma. CASE SUMMARY:We report an 82-year-old woman who presented with a p...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v8.i22.5751
更新日期:2020-11-26 00:00:00
abstract::Colovesical fistulas (CVFs) are rare complications of very advanced cancers of the abdominal or pelvic cavity and often cause diagnostic troubles. CVFs are found more often in males, whereas females usually suffer from rectovaginal or vesicovaginal fistulas. This article presents a case of a female patient who was adm...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v6.i12.538
更新日期:2018-10-26 00:00:00
abstract:BACKGROUND:Femoral shaft fractures are a common type of fracture among adults and have high union rates. However, clinical decisions are difficult to make because of the different types of nonunions. Atrophic nonunion usually requires revision surgery combined with bone grafting. Furthermore, no study of teriparatide a...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v7.i18.2838
更新日期:2019-09-26 00:00:00
abstract:BACKGROUND:Endoscopic ultrasonography-guided fine-needle aspiration (EUS-FNA) and endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) are highly sensitive for diagnosing and staging lung cancer. In recent years, targeted therapy has shown great significance in the treatment of non-small cell lu...
journal_title:World journal of clinical cases
pub_type: 杂志文章
doi:10.12998/wjcc.v8.i21.5139
更新日期:2020-11-06 00:00:00
abstract::Autoimmune encephalitis is a poorly understood condition that can present with a combination of neurological and psychiatric symptoms, either of which may predominate. There are many autoantibodies associated with a variety of clinical syndromes - anti-N-Methyl-D-Aspartate receptor (NMDAR) is the commonest. Currently,...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v4.i8.223
更新日期:2016-08-16 00:00:00
abstract::Hematopoietic stem cell transplantation has become a curative choice of many hematopoietic malignancy, but graft-vs-host disease (GVHD) has limited the survival quality and overall survival of hematopoietic stem cell transplantation. Understanding of the immune cells' reaction in pathophysiology of GVHD has improved, ...
journal_title:World journal of clinical cases
pub_type: 杂志文章,评审
doi:10.12998/wjcc.v8.i10.1793
更新日期:2020-05-26 00:00:00
abstract:BACKGROUND:Since the beginning of the pandemic, coronavirus disease-2019 (COVID-19) in children has shown milder cases and a better prognosis than adults. Although the respiratory tract is the primary target for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), cardiovascular involvement is emerging as one ...
journal_title:World journal of clinical cases
pub_type: 杂志文章
doi:10.12998/wjcc.v8.i21.5250
更新日期:2020-11-06 00:00:00
abstract:BACKGROUND:Inflammatory cytokines play a vital role in the occurrence of osteoarticular injury and inflammation. Whether inflammation-associated factors interleukin-1β (IL-1β), IL-6, tumor necrosis factor-α (TNF-α) and vascular endothelial growth factor (VEGF) are involved in the pathogenesis of keen articular cartilag...
journal_title:World journal of clinical cases
pub_type: 杂志文章
doi:10.12998/wjcc.v7.i11.1262
更新日期:2019-06-06 00:00:00
abstract:BACKGROUND:Myocardial bridge (MB) will compress the mural coronary artery (MCA) during the systole and cause myocardial ischemia. In the diagnosis of coronary heart disease (CHD), because the structure of MB is difficult to be observed by coronary angiography (CAG), the clinical study of the influence of MB on CHD is l...
journal_title:World journal of clinical cases
pub_type: 杂志文章
doi:10.12998/wjcc.v7.i15.1986
更新日期:2019-08-06 00:00:00
abstract::Fine-needle aspiration (FNA) cytology is an important diagnostic tool in patients with thyroid lesions. Several systems have been proposed for the cyropathologic diagnosis of the thyroid nodules. However cases with indeterminate cytological findings still remain a matter of debate. In this review we analyze all litera...
journal_title:World journal of clinical cases
pub_type: 杂志文章,评审
doi:10.12998/wjcc.v4.i2.38
更新日期:2016-02-16 00:00:00
abstract:BACKGROUND:Despite high risk of bacterial contamination, yet there are no studies that have evaluated the optimal hang time of blenderized and reconstituted powdered formulas at standard room temperature and high temperature. AIM:To investigate the optimal hang time of both types of formulas at standard room temperatu...
journal_title:World journal of clinical cases
pub_type: 临床试验
doi:10.12998/wjcc.v8.i19.4410
更新日期:2020-10-06 00:00:00
abstract:BACKGROUND:Systemic amyloidosis in which multiple systems can be involved has become a common clinical disease. When the liver is affected, symptoms such as abdominal distension, fatigue, edema, liver, and jaundice could appear. To date, hepatic amyloidosis combined with hepatic venular occlusive disease and Budd-Chiar...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v7.i20.3282
更新日期:2019-10-26 00:00:00
abstract:BACKGROUND:In December 2019, the first patient with 2019-novel coronavirus (2019-nCoV) was reported in Wuhan, China, and the disease spread rapidly across the country and surrounding countries within 2 mo. As of February 29, 2020, a total of 91 confirmed cases had been reported in Gansu Province. This case report of th...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v8.i17.3903
更新日期:2020-09-06 00:00:00
abstract:BACKGROUND:Concomitant allergic fungal rhinosinusitis (AFRS) and allergic bronchopulmonary aspergillosis (ABPA) are extremely rare, with no more than 20 cases reported in the English literature. CASE SUMMARY:A 52-year-old female patient complained of right-sided nasal obstruction, rhinorrhea, sneezing, epistaxis, and ...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v7.i22.3821
更新日期:2019-11-26 00:00:00
abstract::Esophageal atresia with tracheo-oesophageal fistula (TEF) occurs in 1 in 3500 live births. Anorectal malformation is found to be associated with 14% of TEF. Esophageal atresia with TEF is a congenital anomaly which classically presents as excessive frothing from the mouth and respiratory distress. Rarely gastric posit...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v2.i7.309
更新日期:2014-07-16 00:00:00
abstract::Although Kaposi sarcoma (KS) has been more traditionally considered an AIDS-defining illness, it may also be seen in individuals on immunosuppresive therapy. We report a case of a patient who presented to the hospital in the setting of increasingly refractory ulcerative colitis. Computed tomography scan of the abdomen...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v5.i12.423
更新日期:2017-12-16 00:00:00
abstract:BACKGROUND:Breast cancer (BCa) is one of the most common malignancies in women; however, ureteral metastasis of BCa has rarely been reported in the literature. CASE SUMMARY:A 55-year-old Chinese woman with an 8-year history of BCa presented with lower back pain that had persisted for 3 mo. The patient underwent bilate...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v7.i20.3347
更新日期:2019-10-26 00:00:00
abstract:BACKGROUND:Neurofibromatosis is an autosomal dominant genetic disorder with various manifestations. Systemic multiple neurofibromatosis is rare in infancy. The disease is difficult to identify in the early stage, and it is prone to misdiagnosis and missed diagnosis. In the presence of lower limb swelling with subcutane...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v8.i22.5678
更新日期:2020-11-26 00:00:00
abstract::Idiopathic granulomatous mastitis is a rare chronic inflammatory lesion of the breast that can clinically and radiographically mimic breast carcinoma. The most common clinical presentation is an unilateral, discrete breast mass, nipple retraction and even a sinus formation often associated with an inflammation of the ...
journal_title:World journal of clinical cases
pub_type: 杂志文章,评审
doi:10.12998/wjcc.v2.i12.852
更新日期:2014-12-16 00:00:00