Radiation enteritis: Diagnostic and therapeutic issues.

Abstract:

:Abdominal pelvic radiation therapy can induce acute or chronic lesions in the small bowel wall, called radiation enteritis. Treatment of acute radiation enteritis is essentially symptomatic; symptoms regress when radiation is discontinued. Conversely, late toxicity can occur up to 30 years after discontinuation of radiation therapy, posing diagnostic problems. Approximately one out of five patients treated by radiation therapy will present clinical signs of radiation enteritis, including obstruction, malabsorption, malnutrition and/or other complications. Management should be multidisciplinary, centered mainly on correction of malnutrition. Surgery is indicated in case of complications (i.e., abscess, perforation, fistula) and/or resistance to medical treatment; intestinal resection should be preferred over internal bypass. The main risk in case of iterative resections is the short bowel syndrome and the need for definitive nutritional assistance.

journal_name

J Visc Surg

authors

Loge L,Florescu C,Alves A,Menahem B

doi

10.1016/j.jviscsurg.2020.08.012

subject

Has Abstract

pub_date

2020-12-01 00:00:00

pages

475-485

issue

6

issn

1878-7886

pii

S1878-7886(20)30233-2

journal_volume

157

pub_type

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