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Clinical and Laboratory Diagnosis of SARS-CoV-2, the Virus Causing COVID-19.

Abstract：

:In December 2019, a novel beta (β) coronavirus eventually named SARS-CoV-2 emerged in Wuhan, Hubei province, China, causing an outbreak of severe and even fatal pneumonia in humans. The virus has spread very rapidly to many countries across the world, resulting in the World Health Organization (WHO) to declare a pandemic on March 11, 2020. Clinically, the diagnosis of this unprecedented illness, called coronavirus disease-2019 (COVID-19), becomes difficult because it shares many symptoms with other respiratory pathogens, including influenza and parainfluenza viruses. Therefore, laboratory diagnosis is crucial for the clinical management of patients and the implementation of disease control strategies to contain SARS-CoV-2 at clinical and population level. Here, we summarize the main clinical and imaging findings of COVID-19 patients and discuss the advances, features, advantages, and limitations of different laboratory methods used for SARS-CoV-2 diagnosis.

journal_name

ACS Infect Dis

journal_title

ACS infectious diseases

authors

da Silva SJR,Silva CTAD,Guarines KM,Mendes RPG,Pardee K,Kohl A,Pena L

doi

10.1021/acsinfecdis.0c00274

subject

Has Abstract

pub_date

2020-09-11 00:00:00

pages

2319-2336

issue

9

issn

2373-8227

journal_volume

6

pub_type

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