Spatial modes for transmission of chikungunya virus during a large chikungunya outbreak in Italy: a modeling analysis.

abstract：BACKGROUND:Due to the overlapping clinical features of coronavirus disease 2019 (COVID-19) and influenza, parallels are often drawn between the two diseases. Patients with pre-existing cardiovascular diseases (CVD) are at a higher risk for severe manifestations of both illnesses. Considering the high transmission rate ...

journal_title：BMC medicine

authors： Khan MS,Shahid I,Anker SD,Solomon SD,Vardeny O,Michos ED,Fonarow GC,Butler J

更新日期：2020-12-18 00:00:00

abstract：:Integration of the viral genome into host cell chromatin is a pivotal and unique step in the replication cycle of retroviruses, including HIV. Inhibiting HIV replication by specifically blocking the viral integrase enzyme that mediates this step is an obvious and attractive therapeutic strategy. After concerted effort...

journal_title：BMC medicine

authors： Quashie PK,Sloan RD,Wainberg MA

更新日期：2012-04-12 00:00:00

abstract：BACKGROUND:It is a common practice to use a singleton fetal growth standard to assess twin growth. We aim to create a twin fetal weight standard which is also adjustable for race/ethnicity and other factors. METHODS:Over half a million twin births of low risk pregnancies in the US, from 1995 to 2004, were used to cons...

journal_title：BMC medicine

authors： Zhang J,Mikolajczyk R,Lei X,Sun L,Yu H,Cheng W

更新日期：2015-07-03 00:00:00

abstract：BACKGROUND:In recent years, medical practice has followed two different paradigms: evidence-based medicine (EBM) and values-based medicine (VBM). There is an urgent need to promote medical education that strengthens the relationship between these two paradigms. This work is designed to establish the foundations for a c...

journal_title：BMC medicine

authors： Altamirano-Bustamante MM,Altamirano-Bustamante NF,Lifshitz A,Mora-Magaña I,de Hoyos A,Avila-Osorio MT,Quintana-Vargas S,Aguirre JA,Méndez J,Murata C,Nava-Diosdado R,Martínez-González O,Calleja E,Vargas R,Mejía-Arangure JM,C

更新日期：2013-02-15 00:00:00

abstract：:The Fluid Expansion as Supportive Therapy (FEAST study) was an extremely well conducted study that gave unexpected results. The investigators had reported that febrile children with impaired perfusion treated in low-income countries without access to intensive care are more likely to die if they receive bolus resuscit...

journal_title：BMC medicine

authors： Myburgh J,Finfer S

更新日期：2013-03-14 00:00:00

abstract：BACKGROUND:The United States Preventive Services Task Force (USPSTF) recommends screening adults for depression in primary care settings when staff-assisted depression management programs are available. This recommendation, however, is based on evidence from depression management programs conducted with patients alread...

journal_title：BMC medicine

authors： Thombs BD,Ziegelstein RC,Roseman M,Kloda LA,Ioannidis JP

更新日期：2014-01-28 00:00:00

abstract：BACKGROUND:Although vaccination has been proved to be a safe, efficacious, and cost-effective intervention, immunisation rates remain suboptimal in many European countries, resulting in poor control of many vaccine-preventable diseases. DISCUSSION:The Summit of Independent European Vaccination Experts focused on the p...

journal_title：BMC medicine

authors： Schmitt HJ,Booy R,Aston R,Van Damme P,Schumacher RF,Campins M,Rodrigo C,Heikkinen T,Weil-Olivier C,Finn A,Olcén P,Fedson D,Peltola H

更新日期：2007-05-29 00:00:00

abstract：BACKGROUND:Dietary assessment is complex, and strategies to select the most appropriate dietary assessment tool (DAT) in epidemiological research are needed. The DIETary Assessment Tool NETwork (DIET@NET) aimed to establish expert consensus on Best Practice Guidelines (BPGs) for dietary assessment using self-report. M...

journal_title：BMC medicine

authors： Cade JE,Warthon-Medina M,Albar S,Alwan NA,Ness A,Roe M,Wark PA,Greathead K,Burley VJ,Finglas P,Johnson L,Page P,Roberts K,Steer T,Hooson J,Greenwood DC,Robinson S,DIET@NET consortium.

更新日期：2017-11-15 00:00:00

abstract：BACKGROUND:In July 2014, an outbreak of Ebola virus disease (EVD) started in Pujehun district, Sierra Leone. On January 10th, 2015, the district was the first to be declared Ebola-free by local authorities after 49 cases and a case fatality rate of 85.7%. The Pujehun outbreak represents a precious opportunity for impro...

journal_title：BMC medicine

authors： Ajelli M,Parlamento S,Bome D,Kebbi A,Atzori A,Frasson C,Putoto G,Carraro D,Merler S

更新日期：2015-11-26 00:00:00

abstract：:A series of primarily laboratory-based studies found attention bias modification in socially anxious participants to lead to reduced anxiety. It is argued that the failure to replicate the positive results of attention bias modification in the study of Carlbring et al. may be due to reasons other than the application ...

journal_title：BMC medicine

authors： Emmelkamp PM

更新日期：2012-06-25 00:00:00

abstract：BACKGROUND:Tumor necrosis factor (TNF)-α inhibitors are increasingly being used in inflammatory bowel disease (IBD). Because this chronic intestinal disorder often affects women of fertile age, it is essential to assess the effect of biologics on pregnancy outcome. METHODS:We performed a systematic review of the Engli...

journal_title：BMC medicine

authors： Nielsen OH,Loftus EV Jr,Jess T

更新日期：2013-07-31 00:00:00

abstract：BACKGROUND:Renal impairment is a major risk factor for mortality in various populations. Three formulas are frequently used to assess both glomerular filtration rate (eGFR) or creatinine clearance (CrCl) and mortality prediction: body surface area adjusted-Cockcroft-Gault (CG-BSA), Modification of Diet in Renal Disease...

journal_title：BMC medicine

authors： Ferreira JP,Girerd N,Pellicori P,Duarte K,Girerd S,Pfeffer MA,McMurray JJ,Pitt B,Dickstein K,Jacobs L,Staessen JA,Butler J,Latini R,Masson S,Mebazaa A,Rocca HP,Delles C,Heymans S,Sattar N,Jukema JW,Cleland JG,Za

更新日期：2016-11-10 00:00:00

abstract：BACKGROUND:Comorbidities affect outcomes in heart failure (HF), but are not reflected in current HF classification. The aim of this study is to characterize HF groups that account for higher-order interactions between comorbidities and to investigate the association between comorbidity groups and outcomes. METHODS:Lat...

journal_title：BMC medicine

authors： Gulea C,Zakeri R,Quint JK

更新日期：2021-01-18 00:00:00

abstract：BACKGROUND:Adiposity is associated with many adverse health outcomes but little direct evidence exists about its impact on the use of health care services. We aim to describe the relationship between body mass index (BMI) and rates of hospital admission in middle-aged UK women. METHODS:Among 1,251,619 Million Women St...

journal_title：BMC medicine

authors： Reeves GK,Balkwill A,Cairns BJ,Green J,Beral V,Million Women Study Collaborators.

更新日期：2014-03-15 00:00:00

abstract：BACKGROUND:Resistance and tolerance to Plasmodium falciparum can determine the progression of malaria disease. However, quantitative evidence of tolerance is still limited. We investigated variations in the adverse impact of P. falciparum infections among African pregnant women under different intensities of malaria tr...

journal_title：BMC medicine

authors： Ndam NT,Mbuba E,González R,Cisteró P,Kariuki S,Sevene E,Rupérez M,Fonseca AM,Vala A,Maculuve S,Jiménez A,Quintó L,Ouma P,Ramharter M,Aponte JJ,Nhacolo A,Massougbodji A,Briand V,Kremsner PG,Mombo-Ngoma G,Desai M,

更新日期：2017-07-17 00:00:00

abstract：:In recent years, the introduction and Federal Drug Administration approval of immune checkpoint inhibitor antibodies has dramatically improved the clinical outcomes for patients with advanced melanoma. These antagonist monoclonal antibodies are capable of unleashing dormant or exhausted antitumor immunity, which has l...

journal_title：BMC medicine

authors： Redman JM,Gibney GT,Atkins MB

更新日期：2016-02-06 00:00:00

abstract：BACKGROUND:The inverse equity hypothesis asserts that new health policies initially widen inequality, then attenuate inequalities over time. Since 2004, the UK's pay-for-performance scheme for chronic disease management (CDM) in primary care general practices (the Quality and Outcomes Framework) has permitted practices...

journal_title：BMC medicine

authors： Lowrie R,McConnachie A,Williamson AE,Kontopantelis E,Forrest M,Lannigan N,Mercer SW,Mair FS

更新日期：2017-04-11 00:00:00

abstract：BACKGROUND:Armed conflict can indirectly affect population health through detrimental impacts on political and social institutions and destruction of infrastructure. This study aimed to quantify indirect mortality impacts of armed conflict in civilian populations globally and explore differential effects by armed confl...

journal_title：BMC medicine

authors： Jawad M,Hone T,Vamos EP,Roderick P,Sullivan R,Millett C

更新日期：2020-09-10 00:00:00

abstract：BACKGROUND:Three large new trials of unprecedented scale and cost, which included novel factorial designs, have found no effect of basic water, sanitation and hygiene (WASH) interventions on childhood stunting, and only mixed effects on childhood diarrhea. Arriving at the inception of the United Nations' Sustainable De...

journal_title：BMC medicine

authors： Cumming O,Arnold BF,Ban R,Clasen T,Esteves Mills J,Freeman MC,Gordon B,Guiteras R,Howard G,Hunter PR,Johnston RB,Pickering AJ,Prendergast AJ,Prüss-Ustün A,Rosenboom JW,Spears D,Sundberg S,Wolf J,Null C,Luby SP,Hum

更新日期：2019-08-28 00:00:00

abstract：:The Mediterranean diet has been linked to a number of health benefits, including reduced mortality risk and lower incidence of cardiovascular disease. Definitions of the Mediterranean diet vary across some settings, and scores are increasingly being employed to define Mediterranean diet adherence in epidemiological st...

journal_title：BMC medicine

authors： Trichopoulou A,Martínez-González MA,Tong TY,Forouhi NG,Khandelwal S,Prabhakaran D,Mozaffarian D,de Lorgeril M

更新日期：2014-07-24 00:00:00

abstract：BACKGROUND:Non-alcoholic fatty liver disease (NAFLD) is caused by abnormal accumulation of lipids within liver cells. Its prevalence is increasing in developed countries in association with obesity, and it represents a risk factor for non-alcoholic steatohepatitis (NASH), cirrhosis and hepatocellular carcinoma. Since N...

journal_title：BMC medicine

authors： Jiménez-Agüero R,Emparanza JI,Beguiristain A,Bujanda L,Alustiza JM,García E,Hijona E,Gallego L,Sánchez-González J,Perugorria MJ,Asensio JI,Larburu S,Garmendia M,Larzabal M,Portillo MP,Aguirre L,Banales JM

更新日期：2014-08-26 00:00:00

abstract：:Wheat, once thought to be a critical ingredient in a healthy diet, has become a major threat, according to public opinion. The term non-celiac gluten sensitivity has been widely adopted to describe a clinical entity characterized by symptoms induced by gluten without the diagnostic criteria found in other gluten-relat...

journal_title：BMC medicine

authors： Lundin KE

更新日期：2014-05-23 00:00:00

abstract：BACKGROUND:Castration-resistant prostate cancer (CRPC) is associated with wide variations in survival. Recent studies of whole blood mRNA expression-based biomarkers strongly predicted survival but the genes used in these biomarker models were non-overlapping and their relationship was unknown. We developed a biomarker...

journal_title：BMC medicine

authors： Wang L,Gong Y,Chippada-Venkata U,Heck MM,Retz M,Nawroth R,Galsky M,Tsao CK,Schadt E,de Bono J,Olmos D,Zhu J,Oh WK

更新日期：2015-08-21 00:00:00

abstract：BACKGROUND:Health-related research funders, regulators and journals expect that de-identified individual-level health data be shared widely, with as few restrictions as possible; yet, in reality, the volume of shared data remains low. MAIN BODY:Health researchers and other data producers are reluctant to share their d...

journal_title：BMC medicine

authors： Waithira N,Mutinda B,Cheah PY

更新日期：2019-04-17 00:00:00

abstract：BACKGROUND:Pendred syndrome, an autosomal-recessive disorder characterized by deafness and goiter, is caused by a mutation of SLC26A4, which codes for the anion exchanger pendrin. We investigated the relationship between pendrin expression and deafness using mice that have (Slc26a4+/+ or Slc26a4+/-) or lack (Slc26a4-/-...

journal_title：BMC medicine

authors： Jabba SV,Oelke A,Singh R,Maganti RJ,Fleming S,Wall SM,Everett LA,Green ED,Wangemann P

更新日期：2006-12-22 00:00:00

abstract：BACKGROUND:The mind-body nexus has been a topic of growing interest. Further data are however required to understand the specific relationship between mood and anxiety disorders and individual physical health conditions, and to verify whether these psychiatric disorders are linked to overall medical burden. METHODS:Th...

journal_title：BMC medicine

authors： Sanna L,Stuart AL,Pasco JA,Kotowicz MA,Berk M,Girardi P,Brennan SL,Williams LJ

更新日期：2013-04-24 00:00:00

abstract：BACKGROUND:The prevalence of non-communicable diseases (NCDs) is increasing in sub-Saharan Africa. At the same time, the use of mobile phones is rising, expanding the opportunities for the implementation of mobile phone-based health (mHealth) interventions. This review aims to understand how, why, for whom, and in what...

journal_title：BMC medicine

authors： Opoku D,Stephani V,Quentin W

更新日期：2017-02-06 00:00:00

abstract：BACKGROUND:It is known that antimalarial drugs reduce the risk of low birth weight (LBW) in pregnant patients. However, a previous Cochrane review did not evaluate whether the level of antimalarial drug resistance could modify the protective effect of antimalarial drugs in this regard. In addition, no systematic review...

journal_title：BMC medicine

authors： Muanda FT,Chaabane S,Boukhris T,Santos F,Sheehy O,Perreault S,Blais L,Bérard A

更新日期：2015-08-14 00:00:00

abstract：BACKGROUND:Alcohol consumption is a leading contributor to death and disability worldwide, but previous research has not examined the effects of different patterns of alcohol consumption. The study objective was to understand the relationship between different alcohol consumption patterns and adverse health outcomes ri...

journal_title：BMC medicine

authors： Jani BD,McQueenie R,Nicholl BI,Field R,Hanlon P,Gallacher KI,Mair FS,Lewsey J

更新日期：2021-01-12 00:00:00

abstract：BACKGROUND:Migraine aura may be difficult to differentiate from transient ischemic attacks and other transient neurological disorders in pregnant women. The aims of the present study were to investigate and diagnose all pregnant women with transient neurological disorders of suspected central nervous system origin, and...

journal_title：BMC medicine

authors： Ertresvg JM,Stovner LJ,Kvavik LE,Johnsen HJ,Zwart JA,Helde G,Bovim G

更新日期：2007-07-17 00:00:00