Association Between Diabetes and COVID-19: A Retrospective Observational Study With a Large Sample of 1,880 Cases in Leishenshan Hospital, Wuhan.

abstract：:In addition to the obvious differences in body shape, there are substantial differences in lipid metabolism between men and women. These differences include how dietary fatty acids are handled, the secretion and clearance of very low-density lipoprotein-triglycerides, the release rates of free fatty acids (FFA) from a...

journal_title：Frontiers in endocrinology

authors： Santosa S,Jensen MD

更新日期：2015-07-02 00:00:00

abstract：:Introduction: An increase of serum dehydroepiandrosterone (DHEA) sulfate (DHEAS) is observed in premature adrenarche and congenital adrenal hyperplasia. Very high DHEAS levels are typical for adrenal tumors. Approximately 74% of DHEAS is hydrolyzed to DHEA by the steroid sulfatase (STS). The reverse reaction is DHEA s...

journal_title：Frontiers in endocrinology

authors： Iliev DI,Braun R,Sánchez-Guijo A,Hartmann M,Wudy SA,Heckmann D,Bruchelt G,Rösner A,Grosser G,Geyer J,Binder G

更新日期：2020-05-06 00:00:00

abstract：:Anti-Müllerian hormone reflects the continuum of the functional ovarian reserve, and as such can predict ovarian response to gonadotropin stimulation and be used to individualize treatment pathways to improve efficacy and safety. However, consistent with other biomarkers and age-based prediction models it has limited ...

journal_title：Frontiers in endocrinology

authors： Li HWR,Nelson SM

更新日期：2020-12-09 00:00:00

abstract：:Limb length inequality results from many types of musculoskeletal disorders. Asymmetric weight bearing from a limb length discrepancy of less than 2% can have debilitating consequences such as back problems and early-onset osteoarthritis. Existing treatments include invasive surgeries and/or drug regimens that are oft...

journal_title：Frontiers in endocrinology

authors： Racine HL,Meadows CA,Ion G,Serrat MA

更新日期：2018-06-04 00:00:00

abstract：:Chemokines are small molecules that play a crucial role as chemoattractants for several cell types, and their components are associated with host immune responses and repair mechanisms. Chemokines selectively recruit monocytes, neutrophils, and lymphocytes and induce chemotaxis through the activation of G protein-coup...

journal_title：Frontiers in endocrinology

authors： Siddiqui JA,Partridge NC

更新日期：2017-03-29 00:00:00

abstract：:Pituitary adenomas (PA) are amongst the most prevalent intracranial tumors, causing complications by hormonal overproduction or deficiency and tumor mass effects, with 95% of cases occurring sporadically. Associated germline mutations (AIP, MEN1, CDKN1B, PRKAR1A, SDHx) and Xq26.3 microduplications are increasingly ide...

journal_title：Frontiers in endocrinology

authors： van den Broek MFM,van Nesselrooij BPM,Verrijn Stuart AA,van Leeuwaarde RS,Valk GD

更新日期：2019-12-10 00:00:00

abstract：BACKGROUND:Non-alcoholic fatty liver disease (NAFLD) is one of the most common forms of chronic liver diseases closely associated with obesity and insulin resistance; deficient growth hormone (GH) action in liver has been implicated as a mechanism. Here, we investigated the evolution of NAFLD in aged mice with liver-sp...

journal_title：Frontiers in endocrinology

authors： Fan Y,Fang X,Tajima A,Geng X,Ranganathan S,Dong H,Trucco M,Sperling MA

更新日期：2014-12-18 00:00:00

abstract：:SIRT7 is one of seven mammalian sirtuins that functions as an NAD+-dependent histone/protein deacetylase. SIRT7 is the least well-known member of the sirtuin family, but recent efforts have identified its involvement in various cellular processes, such as ribosome biogenesis, gene expression, cellular metabolism and c...

journal_title：Frontiers in endocrinology

authors： Wu D,Li Y,Zhu KS,Wang H,Zhu WG

更新日期：2018-11-19 00:00:00

abstract：:Women with impaired ovarian reserve or poor ovarian response (POR) to exogenous gonadotropin stimulation present a challenge for reproductive specialists. The primary reasons relate to the still limited knowledge about the POR pathophysiology and the lack of practical solutions for the management of these conditions. ...

journal_title：Frontiers in endocrinology

authors： Esteves SC,Roque M,Bedoschi GM,Conforti A,Humaidan P,Alviggi C

更新日期：2018-08-17 00:00:00

abstract：:We sought to determine the efficacy of 12 weeks high-intensity interval training (HIIT), compared to moderate-intensity continuous training (MICT) on glucose control, cardiometabolic risk and microvascular complication markers in men living with type 2 diabetes (T2D). Both modalities were combined with resistance trai...

journal_title：Frontiers in endocrinology

authors： Wormgoor SG,Dalleck LC,Zinn C,Borotkanics R,Harris NK

更新日期：2018-08-28 00:00:00

abstract：:Many patients with type 1 diabetes (T1D) do not achieve the glycemic target goal with insulin treatment. In this study, we aimed to evaluate the efficacy and safety of add-on to insulin therapy in patients with T1D. We conducted direct and indirect network meta-analyses using Bayesian models and ranked hypoglycemic ag...

journal_title：Frontiers in endocrinology

authors： Kim YJ,Hwang SD,Lim S

更新日期：2020-08-19 00:00:00

abstract：:Gastric cancer although occurring in reduced frequency is still an important disease, partly because of the bad prognosis when occurring in western countries. This decline in occurrence may mainly be due to the reduced prevalence of Helicobacter pylori (Hp) infection, which is the most important cause of gastric cance...

journal_title：Frontiers in endocrinology

authors： Waldum HL,Sagatun L,Mjønes P

更新日期：2017-01-17 00:00:00

abstract：:Background: Carney complex (CNC) is a rare multiple endocrine neoplasia syndrome with autosomal dominant inheritance. Affected individuals present with mucocutaneous lentigines/blue nevi, cardiac and noncardiac myxomatous tumors, and multiple endocrine tumors. Mutations in PRKAR1A have been identified as genetic cause...

journal_title：Frontiers in endocrinology

authors： Ralser DJ,Strizek B,Kupczyk P,Stoffel-Wagner B,Altengarten J,Müller A,Woelfle J,Gembruch U,Klingmueller D,Merz WM,Paschkowiak-Christes A

更新日期：2020-05-08 00:00:00

abstract：:Gonadotropin-releasing hormone (GnRH) is the primary regulator of mammalian reproductive function in both males and females. It acts via G-protein coupled receptors on gonadotropes to stimulate synthesis and secretion of the gonadotropin hormones luteinizing hormone and follicle-stimulating hormone. These receptors co...

journal_title：Frontiers in endocrinology

authors： Perrett RM,McArdle CA

更新日期：2013-11-20 00:00:00

abstract：:Vitiligo represents the most common cause of acquired skin, hair, and oral depigmentation, affecting 0.5-1% of the population worldwide. It is clinically characterized by the appearance of disfiguring circumscribed skin macules following melanocyte destruction by autoreactive cytotoxic T lymphocytes. Patients affected...

journal_title：Frontiers in endocrinology

authors： Baldini E,Odorisio T,Sorrenti S,Catania A,Tartaglia F,Carbotta G,Pironi D,Rendina R,D'Armiento E,Persechino S,Ulisse S

更新日期：2017-10-27 00:00:00

abstract：:Context: The DICER1 syndrome is a multiple neoplasia disorder caused by germline mutations in the DICER1 gene. In DICER1 patients, aggressive congenital pituitary tumors lead to neonatal Cushing's disease (CD). The role of DICER1 in other corticotropinomas, however, remains unknown. Objective: To perform a comprehensi...

journal_title：Frontiers in endocrinology

authors： Martínez de LaPiscina I,Hernández-Ramírez LC,Portillo N,Gómez-Gila AL,Urrutia I,Martínez-Salazar R,García-Castaño A,Aguayo A,Rica I,Gaztambide S,Faucz FR,Keil MF,Lodish MB,Quezado M,Pankratz N,Chittiboina P,Lane J,Kay D

更新日期：2020-07-03 00:00:00

abstract：:Objective: Prolactin and progesterone are implicated in glucose homeostasis in and outside of pregnancy. However, their associations with gestational diabetes (GDM) risk were not well-understood. This study investigates this question in a prospective and longitudinal cohort. Methods: This is a nested case-control stud...

journal_title：Frontiers in endocrinology

authors： Li M,Song Y,Rawal S,Hinkle SN,Zhu Y,Tekola-Ayele F,Ferrara A,Tsai MY,Zhang C

更新日期：2020-02-27 00:00:00

abstract：:The 3D arrangement of porous granular biomaterials usable to fill bone defects has received little study. Granular biomaterials occupy 3D space when packed together in a manner that creates a porosity suitable for the invasion of vascular and bone cells. Granules of beta-tricalcium phosphate (β-TCP) were prepared with...

journal_title：Frontiers in endocrinology

authors： Chappard D,Terranova L,Mallet R,Mercier P

更新日期：2015-10-12 00:00:00

abstract：:Enteroendocrine cells lining the gut epithelium constitute the largest endocrine organ in the body and secrete over 20 different hormones in response to cues from ingested foods and changes in nutritional status. Not only do these hormones convey signals from the gut to the brain via the gut-brain axis, they also act ...

journal_title：Frontiers in endocrinology

authors： Sun EWL,Martin AM,Young RL,Keating DJ

更新日期：2019-01-04 00:00:00

abstract：Background:Nonalcoholic steatohepatitis (NASH) is rapidly becoming a major chronic liver disease worldwide. However, little is known concerning the pathogenesis and progression mechanism of NASH. Our aim here is to identify key genes and elucidate their biological function in the progression from hepatic steatosis to N...

journal_title：Frontiers in endocrinology

authors： Ye J,Lin Y,Wang Q,Li Y,Zhao Y,Chen L,Wu Q,Xu C,Zhou C,Sun Y,Ye W,Bai F,Zhou T

更新日期：2020-11-26 00:00:00

abstract：:Recent evidence indicates that autophagy-mediated mitochondrial homeostasis is crucial for oxidative stress-related brain damage and repair. The highest concentration of melatonin is in the mitochondria of cells, and melatonin exhibits well-known antioxidant properties. We investigated the impact and mechanism involve...

journal_title：Frontiers in endocrinology

authors： Wang DD,Jin MF,Zhao DJ,Ni H

更新日期：2019-08-08 00:00:00

abstract：:The increase of life expectancy has led to the increase of age-related diseases such as osteoporosis. Osteoporosis is characterized by bone weakening promoting the occurrence of fractures with defective bone regeneration. Men aged over 50 have a prevalence for osteoporosis of 20%, which is related to a decline in sex ...

journal_title：Frontiers in endocrinology

authors： Beranger GE,Djedaini M,Battaglia S,Roux CH,Scheideler M,Heymann D,Amri EZ,Pisani DF

更新日期：2015-05-19 00:00:00

abstract：:Ectopic adrenocorticotropic hormone (ACTH) syndrome (EAS) is a rare cause of Cushing syndrome. If routine imaging examinations cannot identify the source of ACTH production, long-term follow-up observation is necessary to determine the etiology. We present the case of a middle-aged male with gradual weight gain and a ...

journal_title：Frontiers in endocrinology

authors： Lu L,Meng Q,Xing X,Yuan T,Zhang H,Li N,Wang Y,Cheng Y,Bai C,Wang H,Cheng X,Xiao Y,Pan B,Li Y,Sun J,Liang Z,Zhu H,Wang R,Lu Z

更新日期：2019-10-22 00:00:00

abstract：Objectives:Based on data from the China National Health Survey, we aimed to examine the association between body height and cardiometabolic disease (CMD) in a large adult population from Shaanxi province, and further to test whether this association was hinged upon other population characteristics. Methods:This popula...

journal_title：Frontiers in endocrinology

authors： Yuan Y,Zhou B,Wang S,Ma J,Dong F,Yang M,Zhang Z,Niu W

更新日期：2020-12-21 00:00:00

abstract：:Cardiovascular disease (CVD) is the leading cause of death globally. It is well-established based on evidence accrued during the last three decades that high plasma concentrations of cholesterol-rich atherogenic lipoproteins are causatively linked to CVD, and that lowering these reduces atherosclerotic cardiovascular ...

journal_title：Frontiers in endocrinology

authors： Borén J,Packard CJ,Taskinen MR

更新日期：2020-07-28 00:00:00

abstract：:Testicular cancer represents the more frequent solid tumor affecting males aged 15-35 years. In the last decades, its incidence showed a progressive increased probably due to genetic and environmental factors. Despite exposure to some viruses such as HIV, HCV, EBV, and HPV is frequently related to cancer development, ...

journal_title：Frontiers in endocrinology

authors： Garolla A,Pizzol D,Bertoldo A,Ghezzi M,Carraro U,Ferlin A,Foresta C

更新日期：2012-12-21 00:00:00

abstract：:Besides aging, a number of non-modifiable lifestyle-related factors, such as smoking, elevated consumption of caffeine and alcohol, stress, agonist sports, chronic exposure to environmental pollutants, and other nutritional habits exert a negative impact on a women's fertility. In particular, metabolic disorders inclu...

journal_title：Frontiers in endocrinology

authors： Silvestris E,Lovero D,Palmirotta R

更新日期：2019-06-07 00:00:00

abstract：:[This corrects the article DOI: 10.3389/fendo.2017.00018.]. ...

journal_title：Frontiers in endocrinology

authors： Sekar R,Wang L,Chow BKC

更新日期：2018-07-18 00:00:00

abstract：:Accumulating evidence shows that H2S has physiological functions in various tissues and organs. It includes regulation of neuronal activity, vascular tension, a release of insulin, and protection of the heart, kidney, and brain from ischemic insult. H2S is produced by enzymes from l-cysteine; cystathionine β-synthase,...

journal_title：Frontiers in endocrinology

authors： Shibuya N,Kimura H

更新日期：2013-07-16 00:00:00

abstract：:Classically, the modulation of brain function and behavior by steroid hormones was linked exclusively to secretion by peripheral endocrine glands. Subsequently, steroid actions within the brain were shown dependent upon either synthesis and secretion by peripheral organs or by production within the CNS itself using pe...

journal_title：Frontiers in endocrinology

authors： Remage-Healey L,Saldanha CJ,Schlinger BA

更新日期：2011-09-29 00:00:00