Non-fluent/Agrammatic Variant of Primary Progressive Aphasia With Generalized Auditory Agnosia.

abstract：:Background: Chronic progressive neurological diseases like high grade glioma (HGG), Parkinson's disease (PD), and multiple sclerosis (MS) are incurable, and associated with increasing disability including cognitive impairment, and reduced life expectancy. Patients with these diseases have complex care needs. Therefore...

journal_title：Frontiers in neurology

authors： Walter HAW,Seeber AA,Willems DL,de Visser M

更新日期：2019-01-14 00:00:00

abstract：:Over the past decade, it was found that relatively simple sphingolipids, such as ceramide, sphingosine, sphingosine-1-phosphate, and glucosylceramide play important roles in neuronal functions by regulating rates of neuronal growth and differentiation. Homeostasis of membrane sphingolipids in neurons and myelin is ess...

journal_title：Frontiers in neurology

authors： Alessenko AV,Albi E

更新日期：2020-05-21 00:00:00

abstract：:The involvement of the central nervous system (CNS) in Hodgkin lymphoma (HL) has been rarely reported, especially in its primary isolated form. Herein, we present a case of a 33-year-old woman, who received immunosuppressive treatment due to ulcerative colitis (at the beginning azathioprine and sulfasalazine, changed ...

journal_title：Frontiers in neurology

authors： Szczepanek D,Szumiło J,Stoma F,Szymczyk A,Jarosz B,Szczepanek A,Hus M,Trojanowski T,Wasik-Szczepanek E

更新日期：2020-09-08 00:00:00

abstract：:Microglia are activated during pathological events in the brain and are capable of releasing various types of inflammatory cytokines. Here, we demonstrate that the addition of 5% microglia activated by 1 μg/ml lipopolysaccharides (LPS) to hippocampal cultures upregulates Na(+) current densities (INavD) of bipolar as w...

journal_title：Frontiers in neurology

authors： Klapal L,Igelhorst BA,Dietzel-Meyer ID

更新日期：2016-03-30 00:00:00

abstract：:Background: There is very limited information on the relationship between non-alcoholic fatty liver disease (NAFLD) and the severity or functional outcomes of ischemic stroke or transient ischemic stroke (TIA). We investigated the correlation between NAFLD and stroke outcomes. Methods: NAFLD was assessed in 321 patien...

journal_title：Frontiers in neurology

authors： Baik M,Kim SU,Nam HS,Heo JH,Kim YD

更新日期：2019-04-12 00:00:00

abstract：:We report a case of spontaneous intracerebral hemorrhage (sICH) due to delta storage pool disease in a 60-year-old female on a serotonin-norepinephrine reuptake inhibitor (SNRI). Increased susceptibility to SNRI-effects on hemostasis was due to a genetic disposition mediated by a polymorphism of the SLC6A4 gene coding...

journal_title：Frontiers in neurology

authors： Leibetseder A,Wagner J,Tomasits J,Haring HP,Hutterer M,Trenkler J,von Oertzen TJ

更新日期：2019-11-26 00:00:00

abstract：:Huntington's disease (HD) is an autosomal dominant neurodegenerative genetic disorder characterized by motor, cognitive, and psychiatric symptoms. It is well established that regular physical activity supports brain health, benefiting cognitive function, mental health as well as brain structure and plasticity. Exercis...

journal_title：Frontiers in neurology

authors： Paré MF,Jasmin BJ

更新日期：2017-09-27 00:00:00

abstract：BACKGROUND:Unlike many other central nervous system (CNS) tumors, the surgical management of primary central nervous system lymphomas (PCNSL) is traditionally limited by diagnostic biopsy. Studies that predate the use of modern neurosurgical techniques have reported a prohibitive operative morbidity for this surgery. T...

journal_title：Frontiers in neurology

authors： Yun J,Yang J,Cloney M,Mehta A,Singh S,Iwamoto FM,Neugut AI,Sonabend AM

更新日期：2017-09-12 00:00:00

abstract：:Functional magnetic resonance imaging studies suggest that different subcortico-cortical circuits control different aspects of Parkinsonian rest tremor. The basal ganglia were proposed to drive tremor onset, and the cerebellum was suggested to be responsible for tremor maintenance ("dimmer-switch" hypothesis). Althoug...

journal_title：Frontiers in neurology

authors： Hirschmann J,Abbasi O,Storzer L,Butz M,Hartmann CJ,Wojtecki L,Schnitzler A

更新日期：2019-03-07 00:00:00

abstract：INTRODUCTION:In tinnitus treatment, there is a tendency to shift from a "one size fits all" to a more individual, patient-tailored approach. Insight in the heterogeneity of the tinnitus spectrum might improve the management of tinnitus patients in terms of choice of treatment and identification of patients with severe ...

journal_title：Frontiers in neurology

authors： van den Berge MJC,Free RH,Arnold R,de Kleine E,Hofman R,van Dijk JMC,van Dijk P

更新日期：2017-04-03 00:00:00

abstract：BACKGROUND:Accurate recognition of stroke symptoms by Emergency Medical Services (EMS) is necessary for timely care of acute stroke patients. We assessed the accuracy of stroke diagnosis by EMS in clinical practice in a major US city. METHODS AND RESULTS:Philadelphia Fire Department data were merged with data from a s...

journal_title：Frontiers in neurology

authors： Jia J,Band R,Abboud ME,Pajerowski W,Guo M,David G,Mechem CC,Messé SR,Carr BG,Mullen MT

更新日期：2017-09-14 00:00:00

abstract：Background/objectives:Although the current evidence is insufficient to recommend a special diet for people with multiple sclerosis (MS), dietary advice for people with MS is prolific online and in the media. This study aimed to describe dietary changes made in the year following a first clinical diagnosis of central ne...

journal_title：Frontiers in neurology

authors： Russell RD,Lucas RM,Brennan V,Sherriff JL,Begley A,Ausimmune Investigator Group.,Black LJ

更新日期：2018-03-20 00:00:00

abstract：BACKGROUND:Neurological complications are common after orthotopic liver transplantation (OLT). We aimed to characterize the risk factors associated with neurological complications and mortality among patients who underwent OLT in the post-model for end-stage liver disease (MELD) era. METHODS:In a retrospective review,...

journal_title：Frontiers in neurology

authors： Fu KA,DiNorcia J,Sher L,Velani SA,Akhtar S,Kalayjian LA,Sanossian N

更新日期：2014-12-17 00:00:00

abstract：:Neuroinflammation is one of the most important processes involved in the pathogenesis of Parkinson's disease (PD). The current concept of neuroinflammation comprises an inflammation process, which occurs in the central nervous system due to molecules released from brain-resident and/or blood-derived immune cells. Furt...

journal_title：Frontiers in neurology

authors： Troncoso-Escudero P,Parra A,Nassif M,Vidal RL

更新日期：2018-10-15 00:00:00

abstract：:Accurate localization of the Seizure Onset Zone (SOZ) is crucial in patients with drug-resistance focal epilepsy. EEG with fMRI recording (EEG-fMRI) has been proposed as a complementary non-invasive tool, which can give useful additional information in the pre-surgical work-up. However, fMRI maps related to interictal...

journal_title：Frontiers in neurology

authors： Vaudano AE,Avanzini P,Tassi L,Ruggieri A,Cantalupo G,Benuzzi F,Nichelli P,Lemieux L,Meletti S

更新日期：2013-11-14 00:00:00

abstract：:Background: Neurofilament light chain (NFL) was believed to be a promising biomarker for the diagnosis of Amyotrophic lateral sclerosis (ALS) and disease burden evaluation. Objective: To determine the serum NFL level and its clinical relevance, including its association with disease severity [evaluated by the ALS Func...

journal_title：Frontiers in neurology

authors： Sugimoto K,Han Y,Song Y,Gao Y

更新日期：2020-12-03 00:00:00

abstract：:Objective: To investigate the dynamic amplitude of low-frequency fluctuations (dALFFs) in patients with Parkinson's disease (PD) and healthy controls (HCs) and further explore whether dALFF can be used to test the feasibility of differentiating PD from HCs. Methods: Twenty-eight patients with PD and 28 demographically...

journal_title：Frontiers in neurology

authors： Zhang C,Dou B,Wang J,Xu K,Zhang H,Sami MU,Hu C,Rong Y,Xiao Q,Chen N,Li K

更新日期：2019-10-01 00:00:00

abstract：:Background: Giant vertebrobasilar aneurysms (GVBAs) have an unfavorable natural history if left untreated and often pose a sizeable challenge to endovascular treatment. The aim of this study was to analyze the angiographic and clinical outcomes of GVBAs treated by various endovascular procedures. Methods: Between Janu...

journal_title：Frontiers in neurology

authors： Li M,Liang H,Wang J

更新日期：2020-08-11 00:00:00

abstract：:Alzheimer's disease is the most common neurodegenerative form of dementia that steadily worsens and eventually leads to death. Its set of symptoms include loss of cognitive function and memory decline. Structural and functional imaging methods such as CT, MRI, and PET scans play an essential role in the diagnosis proc...

journal_title：Frontiers in neurology

authors： Gionfrida L,Roginska A

更新日期：2017-12-07 00:00:00

abstract：:Objective: The platelet-to-lymphocyte ratio (PLR) is a new marker of atherosclerotic inflammation and has been identified as a predictive factor in cardiovascular diseases, but its significance in patients with acute ischaemic stroke (AIS) who have undergone intravenous thrombolysis (IVT) is still unknown. Methods: Co...

journal_title：Frontiers in neurology

authors： Xu JH,He XW,Li Q,Liu JR,Zhuang MT,Huang FF,Bao GS

更新日期：2019-11-13 00:00:00

abstract：:Background and Purpose: Although vertebrobasilar ectasia (VBE) is diagnosed with increasing frequency, it is not clear whether this is because of altered hemodynamics caused by the effects of matrix metalloproteinases (MMPs) and/or vertebral artery dominance (VAD). Therefore, we investigate the relationship between pl...

journal_title：Frontiers in neurology

authors： Zhang HL,Peng YF,Zhang DP,Li D,Liu FX,Zhao M,Yin S,Liang JX,Wei TT

更新日期：2020-08-25 00:00:00

abstract：:Background: Writer's cramp (WC) is a task-specific focal hand dystonia presenting with pain, stiffness and/or tremor while writing. We explored the involvement of cortical and brainstem circuits by measuring intermuscular coherence (IMC) and pre-pulse inhibition (PPI) of the blink reflex. Methods: IMC was measured in ...

journal_title：Frontiers in neurology

authors： Choudhury S,Singh R,Chatterjee P,Trivedi S,Shubham S,Baker MR,Kumar H,Baker SN

更新日期：2018-07-02 00:00:00

abstract：:Infections in the post-acute phase of cerebral ischaemia impede optimal recovery by exacerbating morbidity and mortality. Our review aims to reconcile the increased infection susceptibility of patients post-stroke by consolidating our understanding of compartmentalised alterations to systemic immunity. Mounting eviden...

journal_title：Frontiers in neurology

authors： Krishnan S,Lawrence CB

更新日期：2019-07-02 00:00:00

abstract：:Background: Transcranial direct current stimulation (tDCS) and therapy-based virtual reality (VR) have been investigated separately. They have shown promise as efficient and engaging new tools in the neurological rehabilitation of individuals with cerebral palsy (CP). However, the recent literature encourages investig...

journal_title：Frontiers in neurology

authors： da Silva TD,Fontes AMGG,de Oliveira-Furlan BS,Roque TT,Lima AII,de Souza BMM,Alberissi CAO,Silveira AC,de Moraes ÍAP,Collett J,Silva RP,Airoldi MJ,Ribeiro-Papa DC,Dawes H,Monteiro CBM

更新日期：2020-09-02 00:00:00

abstract：:Background and Objective: Parkinson disease (PD) with rapid eye movement (REM) sleep behavior disorder (PD-RBD) tend to be a distinct phenotype with more severe clinical characteristics and pathological lesion when compared with PD without RBD (PD-nRBD). However, the pathological mechanism underlying PD-RBD remains un...

journal_title：Frontiers in neurology

authors： Li J,Zeng Q,Zhou W,Zhai X,Lai C,Zhu J,Dong S,Lin Z,Cheng G

更新日期：2020-10-27 00:00:00

abstract：:Subcortical circuits mediating sleep-wake functions have been well characterized in animal models, and corroborated by more recent human studies. Disruptions in these circuits have been identified in hypersomnia disorders (HDs) such as narcolepsy and Kleine-Levin Syndrome, as well as in neurodegenerative disorders exp...

journal_title：Frontiers in neurology

authors： Larson-Prior LJ,Ju YE,Galvin JE

更新日期：2014-09-11 00:00:00

abstract：:Psychophysiological investigations of traumatic brain injury (TBI) are being conducted for several reasons, including the objective of learning more about the underlying physiological mechanisms of the pathological processes that can be initiated by a head injury. Additional goals include the development of objective ...

journal_title：Frontiers in neurology

authors： Rapp PE,Rosenberg BM,Keyser DO,Nathan D,Toruno KM,Cellucci CJ,Albano AM,Wylie SA,Gibson D,Gilpin AM,Bashore TR

更新日期：2013-07-22 00:00:00

abstract：:Studies of traumatic brain injury from all causes have found evidence of chronic hypopituitarism, defined by deficient production of one or more pituitary hormones at least 1 year after injury, in 25-50% of cases. Most studies found the occurrence of posttraumatic hypopituitarism (PTHP) to be unrelated to injury sever...

journal_title：Frontiers in neurology

authors： Wilkinson CW,Pagulayan KF,Petrie EC,Mayer CL,Colasurdo EA,Shofer JB,Hart KL,Hoff D,Tarabochia MA,Peskind ER

更新日期：2012-02-07 00:00:00

abstract：:Introduction: Stroke rehabilitation should start early in order to optimize patients' outcomes, but most trials include subacute or chronic patients. Although suggested that early stroke rehabilitation trials face difficulties regarding patient recruitment with corresponding low recruitment rates, no systematically co...

journal_title：Frontiers in neurology

authors： Held JPO,van Duinen J,Luft AR,Veerbeek JM

更新日期：2019-07-02 00:00:00

abstract：:Background: The relationship between varicella-zoster virus (VZV)-associated myelitis and aquaporin-4 immunoglobulin-G (AQP4-IgG) remains unknown. Case Report: We report a case of acute radiculomyelitis with longitudinal extensive hyperintensity signals traversing the brainstem until the upper thoracic cord in a 55-ye...

journal_title：Frontiers in neurology

authors： Eguchi H,Takeshige H,Nakajima S,Kanou M,Nakajima A,Fuse A,Fukae J,Miwa H,Shimo Y

更新日期：2020-11-23 00:00:00