Modulation on Glutamic Pathway of Frontal-Striatum-Thalamus by rs11146020 and rs3813296 Gene Polymorphism in First-Episode Negative Schizophrenia.

abstract：:[This corrects the article DOI: 10.3389/fnins.2019.01334.]. ...

journal_title：Frontiers in neuroscience

authors： Ooi LQR,Wen MC,Ng SY,Chia NS,Chew IHM,Lee W,Xu Z,Hartono S,Tan EK,Chan LL,Tan LC

更新日期：2020-05-12 00:00:00

abstract：:Gene Expression Programming (GEP), a variant of Genetic Programming (GP), is a well established technique for automatic generation of computer programs. Due to the flexible representation, GEP has long been concerned as a classification algorithm for various applications. Whereas, GEP cannot be extended to multi-class...

journal_title：Frontiers in neuroscience

authors： Wei T,Zhong J

更新日期：2020-01-17 00:00:00

abstract：:Musical training has recently gained additional interest in education as increasing neuroscientific research demonstrates its positive effects on brain development. Neuroimaging revealed plastic changes in the brains of adult musicians but it is still unclear to what extent they are the product of intensive music trai...

journal_title：Frontiers in neuroscience

authors： Miendlarzewska EA,Trost WJ

更新日期：2014-01-20 00:00:00

abstract：:Introduction: Spasticity is a typical motor disorder in patients affected by stroke. Typically post-stroke rehabilitation consists of repetition of mobilization exercises on impaired limbs, aimed to reduce muscle hypertonia and mitigate spastic reflexes. It is currently strongly debated if the treatment's effectivenes...

journal_title：Frontiers in neuroscience

authors： Crea S,Cempini M,Mazzoleni S,Carrozza MC,Posteraro F,Vitiello N

更新日期：2017-05-12 00:00:00

abstract：:We describe the steps involved in analysis of multi-modal, multi-subject human neuroimaging data using the SPM12 free and open source software (https://www.fil.ion.ucl.ac.uk/spm/) and a publically-available dataset organized according to the Brain Imaging Data Structure (BIDS) format (https://openneuro.org/datasets/ds...

journal_title：Frontiers in neuroscience

authors： Henson RN,Abdulrahman H,Flandin G,Litvak V

更新日期：2019-04-24 00:00:00

abstract：:Glutamate-induced excitotoxicity is common in the pathogenesis of many neurological diseases. A pulsed electromagnetic field (PEMF) exerts therapeutic effects on the nervous system, but its specific mechanism associated with excitotoxicity is still unknown. We investigated the role of PEMF exposure in regulating gluta...

journal_title：Frontiers in neuroscience

authors： Li X,Xu H,Lei T,Yang Y,Jing D,Dai S,Luo P,Xu Q

更新日期：2017-02-06 00:00:00

abstract：:In healthy older adults, resveratrol supplementation has been shown to improve long-term glucose control, resting-state functional connectivity (RSFC) of the hippocampus, and memory function. Here, we aimed to investigate if these beneficial effects extend to individuals at high-risk for dementia, i.e., patients with ...

journal_title：Frontiers in neuroscience

authors： Köbe T,Witte AV,Schnelle A,Tesky VA,Pantel J,Schuchardt JP,Hahn A,Bohlken J,Grittner U,Flöel A

更新日期：2017-03-07 00:00:00

abstract：:In the present review, we deliver an overview of the involvement of metabotropic glutamate receptor 5 (mGluR5) activity and density in pathological anxiety, mood disorders and addiction. Specifically, we will describe mGluR5 studies in humans that employed Positron Emission Tomography (PET) and combined the findings w...

journal_title：Frontiers in neuroscience

authors： Terbeck S,Akkus F,Chesterman LP,Hasler G

更新日期：2015-03-18 00:00:00

abstract：:The neural generators of the frequency-following response (FFR), a neural response widely used to study the human auditory system, remain unclear. There is evidence that the balance between cortical and subcortical contributions to the FFR varies with stimulus frequency. In this study, we tried to clarify whether this...

journal_title：Frontiers in neuroscience

authors： Zhang X,Gong Q

更新日期：2019-02-26 00:00:00

abstract：BACKGROUND:With the advent of the GeneChip Exon Arrays, it is now possible to extract "exon-level" expression estimates, allowing for detection of alternative splicing events, one of the primary mechanisms of transcript diversity. In the context of (1) a complex trait use case and (2) a human cerebellum vs. heart compa...

journal_title：Frontiers in neuroscience

authors： Laderas TG,Walter NA,Mooney M,Vartanian K,Darakjian P,Buck K,Harrington CA,Belknap J,Hitzemann R,McWeeney SK

更新日期：2011-05-13 00:00:00

abstract：:Inducing somatic cells into neural stem cells (iNSCs) in specific ways provides a new cell therapy in a variety of neurological diseases. In the past, iNSCs were generated by transcription factors which increased the risk of mutagenesis, tumor formations, and immune reactions by viral transduction vectors. Therefore, ...

journal_title：Frontiers in neuroscience

authors： Duan Q,Li S,Wen X,Sunnassee G,Chen J,Tan S,Guo Y

更新日期：2019-09-04 00:00:00

abstract：:A novel analytical framework combined fuzzy learning and complex network approaches is proposed for the identification of Alzheimer's disease (AD) with multichannel scalp-recorded electroencephalograph (EEG) signals. Weighted visibility graph (WVG) algorithm is first applied to transform each channel EEG into network ...

journal_title：Frontiers in neuroscience

authors： Yu H,Zhu L,Cai L,Wang J,Liu J,Wang R,Zhang Z

更新日期：2020-07-21 00:00:00

abstract：:Compared to standard laboratory protocols, the measurement of psychophysiological signals in real world experiments poses technical and methodological challenges due to external factors that cannot be directly controlled. To address this problem, we propose a hybrid approach based on an immersive and human accessible ...

journal_title：Frontiers in neuroscience

authors： Betella A,Zucca R,Cetnarski R,Greco A,Lanatà A,Mazzei D,Tognetti A,Arsiwalla XD,Omedas P,De Rossi D,Verschure PF

更新日期：2014-09-24 00:00:00

abstract：:There is a need for reliable and objective measures of early and mild symptomology in multiple sclerosis (MS), as deficits can be subtle and difficult to quantify objectively in patients without overt physical deficits. We hypothesized that a speech-in-noise (SiN) task would be sensitive to demyelinating effects on pr...

journal_title：Frontiers in neuroscience

authors： Iva P,Fielding J,Clough M,White O,Godic B,Martin R,Rajan R

更新日期：2020-12-23 00:00:00

abstract：:Uncovering brain activity from magnetoencephalography (MEG) data requires solving an ill-posed inverse problem, greatly confounded by noise, interference, and correlated sources. Sparse reconstruction algorithms, such as Champagne, show great promise in that they provide focal brain activations robust to these confoun...

journal_title：Frontiers in neuroscience

authors： Owen JP,Sekihara K,Nagarajan SS

更新日期：2012-12-26 00:00:00

abstract：:It was evidenced that impairment of calcium homeostasis is a potential mechanism in the development of Alzheimer's disease (AD). It remains, however, unclear how the calcium signaling are associated with in AD progression. Here we review recent studies to discuss the relationship among the signaling of intracellular c...

journal_title：Frontiers in neuroscience

authors： Wang JM,Sun C

更新日期：2010-12-02 00:00:00

abstract：:Both anodal transcranial direct current stimulation (tDCS) of the left IFG and cathodal stimulation of the right IFG were shown to improve rehabilitation of stroke patients with Broca's aphasia. The study aimed at assessing the impact of a bihemispheric IFG stimulation compared to sham on postacute non-fluent aphasia....

journal_title：Frontiers in neuroscience

authors： Feil S,Eisenhut P,Strakeljahn F,Müller S,Nauer C,Bansi J,Weber S,Liebs A,Lefaucheur JP,Kesselring J,Gonzenbach R,Mylius V

更新日期：2019-04-26 00:00:00

abstract：:This paper presents a real-time, low-complexity neuromorphic speech recognition system using a spiking silicon cochlea, a feature extraction module and a population encoding method based Neural Engineering Framework (NEF)/Extreme Learning Machine (ELM) classifier IC. Several feature extraction methods with varying mem...

journal_title：Frontiers in neuroscience

authors： Acharya J,Patil A,Li X,Chen Y,Liu SC,Basu A

更新日期：2018-03-28 00:00:00

abstract：:The formation of the six-layered structure of the mammalian cortex via the inside-out pattern of neuronal migration is fundamental to neocortical functions. Extracellular cues such as Reelin induce intracellular signaling cascades through the protein phosphorylation. Migrating neurons also have intrinsic machineries t...

journal_title：Frontiers in neuroscience

authors： Ohshima T

更新日期：2015-01-13 00:00:00

abstract：:Environmental sounds form part of our daily life. With the advancement of deep learning models and the abundance of training data, the performance of automatic sound classification (ASC) systems has improved significantly in recent years. However, the high computational cost, hence high power consumption, remains a ma...

journal_title：Frontiers in neuroscience

authors： Wu J,Chua Y,Zhang M,Li H,Tan KC

更新日期：2018-11-19 00:00:00

abstract：:It is undisputed that presenting a rhythmic stimulus leads to a measurable brain response that follows the rhythmic structure of this stimulus. What is still debated, however, is the question whether this brain response exclusively reflects a regular repetition of evoked responses, or whether it also includes entraine...

journal_title：Frontiers in neuroscience

authors： Zoefel B,Ten Oever S,Sack AT

更新日期：2018-03-07 00:00:00

abstract：:Alzheimer's disease (AD) and Type 2 Diabetes Mellitus (T2DM) are two of the most prevalent diseases in the elderly population worldwide. A growing body of epidemiological studies suggest that people with T2DM are at a higher risk of developing AD. Likewise, AD brains are less capable of glucose uptake from the surroun...

journal_title：Frontiers in neuroscience

authors： Chatterjee S,Mudher A

更新日期：2018-06-08 00:00:00

abstract：:Circadian rhythms of behavior and physiology are generated by central and peripheral circadian oscillators entrained by periodic environmental or physiological stimuli. A master circadian pacemaker in the hypothalamic suprachiasmatic nucleus (SCN) is directly entrained by daily light-dark (LD) cycles, and coordinates ...

journal_title：Frontiers in neuroscience

authors： Patton DF,Mistlberger RE

更新日期：2013-10-14 00:00:00

abstract：:Transcutaneous Vagus Nerve Stimulation (tVNS) on the auricular branch of the vagus nerve has been receiving attention due to its therapeutic potential for neuropsychiatric disorders. Although the mechanism of tVNS is not yet completely understood, studies have demonstrated the potential role of vagal afferent nerve st...

journal_title：Frontiers in neuroscience

authors： Jin Y,Kong J

更新日期：2017-01-20 00:00:00

abstract：OBJECTIVES:The thickness of the brain's cortical gray matter (GM) and the fractional anisotropy (FA) of the cerebral white matter (WM) each follow an inverted U-shape trajectory with age. The two measures are positively correlated and may be modulated by common biological mechanisms. We employed four types of genetic a...

journal_title：Frontiers in neuroscience

authors： Kochunov P,Glahn DC,Nichols TE,Winkler AM,Hong EL,Holcomb HH,Stein JL,Thompson PM,Curran JE,Carless MA,Olvera RL,Johnson MP,Cole SA,Kochunov V,Kent J,Blangero J

更新日期：2011-10-19 00:00:00

abstract：:Resting-state functional magnetic resonance imaging (rs-fMRI) is a widely used technique for mapping the brain's functional architecture, so delineating the main sources of variance comprising the signal is crucial. Low frequency oscillations (LFO) that are not of neural origin, but which are driven by mechanisms rela...

journal_title：Frontiers in neuroscience

authors： Whittaker JR,Driver ID,Venzi M,Bright MG,Murphy K

更新日期：2019-05-07 00:00:00

abstract：:Blood-brain barrier opening (BBBO) with pulsed Focused Ultrasound (pFUS) and microbubbles (MB) has received increasing interest as a method for neurotherapeutics of the central nervous system. In general, conventional MRI [i.e., T2w, T2∗w, gadolinium (Gd) enhanced T1w] is used to monitor the effects of pFUS+MB on BBBO...

journal_title：Frontiers in neuroscience

authors： Tu TW,Kovacs ZI,Sundby M,Witko JA,Papadakis GZ,Reid WC,Hammoud DA,Frank JA

更新日期：2020-08-25 00:00:00

abstract：:The combination of electromyography (EMG) and transcranial magnetic stimulation (TMS) offers a powerful non-invasive approach for investigating corticospinal excitability in both humans and animals. Acquiring and analyzing the data produced with this combination of tools requires overcoming multiple technical hurdles....

journal_title：Frontiers in neuroscience

authors： Jackson N,Greenhouse I

更新日期：2019-09-13 00:00:00

abstract：:Objects: Sensorineural hearing loss (SNHL) involves wide-ranging functional reorganization, and is associated with accumulating risk of cognitive and emotional dysfunction. The coordination of multiple functional networks supports normal brain functions. Here, we aimed to evaluate the functional connectivity (FC) patt...

journal_title：Frontiers in neuroscience

authors： Luan Y,Wang C,Jiao Y,Tang T,Zhang J,Teng GJ

更新日期：2019-02-05 00:00:00

abstract：:A large body of experimental and clinical evidence has strongly suggested that monoamines play an important role in regulating epileptogenesis, seizure susceptibility, convulsions, and comorbid psychiatric disorders commonly seen in people with epilepsy (PWE). However, neither the relative significance of individual m...

journal_title：Frontiers in neuroscience

authors： Svob Strac D,Pivac N,Smolders IJ,Fogel WA,De Deurwaerdere P,Di Giovanni G

更新日期：2016-11-10 00:00:00