Abstract:
:Patients with Mycobacterium avium complex lung disease treated with amikacin liposome inhalation suspension (ALIS) at 2 clinics in the United States were surveyed to assess the frequency and management of ALIS-associated respiratory adverse events. Most respondents experienced these events, but management through physician-guided measures (eg, bronchodilator use, oral rinses, and/or temporary dosing adjustments) resulted in symptomatic improvement.
journal_name
Open Forum Infect Disjournal_title
Open forum infectious diseasesauthors
Swenson C,Lapinel NC,Ali Jdoi
10.1093/ofid/ofaa079subject
Has Abstractpub_date
2020-03-02 00:00:00pages
ofaa079issue
4issn
2328-8957pii
ofaa079journal_volume
7pub_type
杂志文章abstract:Background:US hematopoietic cell transplantation (HCT) recipients have a low prevalence of latent tuberculosis infection (LTBI), but if latently infected they are at risk for progression to active tuberculosis. At our center, all HCT recipients underwent LTBI testing pretransplant by tuberculin skin testing (TST) until...
journal_title:Open forum infectious diseases
pub_type: 杂志文章
doi:10.1093/ofid/ofaa224
更新日期:2020-06-10 00:00:00
abstract::Cryptococcus gattii infections, especially including those with severe clinical manifestations, may be related to underlying host immunologic factors. We present 2 cases with autoantibodies to granulocyte-macrophage colony-stimulating factor (GM-CSF), a key cytokine in macrophage function. Immunologic evaluation for a...
journal_title:Open forum infectious diseases
pub_type: 杂志文章
doi:10.1093/ofid/ofx211
更新日期:2017-10-05 00:00:00
abstract::Human immunodeficiency virus-infected women with central adiposity switched to raltegravir-based antiretroviral therapy immediately or after 24 weeks. No statistically significant changes in computed tomography-quantified visceral adipose tissue (VAT) or subcutaneous fat were observed, although 48 weeks of raltegravir...
journal_title:Open forum infectious diseases
pub_type: 杂志文章
doi:10.1093/ofid/ofv059
更新日期:2015-04-26 00:00:00
abstract::We report on a case of loiasis revealed during an assisted reproductive technology (ART) cycle. Loa loa could limit implantation outcome. We propose to focus on an ART strategy with frozen embryos to treat the patient before any transfer. ...
journal_title:Open forum infectious diseases
pub_type: 杂志文章
doi:10.1093/ofid/ofx208
更新日期:2017-10-06 00:00:00
abstract::Burkholderia pseudomallei and Burkholderia cepacia complex are poorly studied in Mexico. The genotypic analysis of 38 strains isolated from children with pneumonia were identified and showed that both Burkholderia groups were present in patients. From our results, it is plausible to suggest that new species are among ...
journal_title:Open forum infectious diseases
pub_type: 杂志文章
doi:10.1093/ofid/ofz008
更新日期:2019-01-18 00:00:00
abstract::This is a single-center retrospective observational cohort study comparing daptomycin/ceftaroline combination therapy with rifampin-adjunct therapy for the treatment of staphylococcal device infections. The results of this study support use of the daptomycin/ceftaroline as an alternative or salvage option to standard ...
journal_title:Open forum infectious diseases
pub_type: 杂志文章
doi:10.1093/ofid/ofaa072
更新日期:2020-02-28 00:00:00
abstract:Background:Recent studies have favored the use of cefazolin over nafcillin for the treatment of methicillin-susceptible Staphylococcus aureus (MSSA) bacteremia. The clinical influence of the cefazolin inoculum effect (CzIE) in the effectiveness of cephalosporins for severe MSSA infections has not been evaluated. Metho...
journal_title:Open forum infectious diseases
pub_type: 杂志文章
doi:10.1093/ofid/ofy123
更新日期:2018-05-23 00:00:00
abstract:Background:Few published studies exist to describe the off-label use of multiple-dose fosfomycin for outpatient treatment of complicated urinary tract infections (UTI). The purpose of this study was to characterize the patients, infections, drug susceptibilities, and outcomes of multiple-dose fosfomycin episodes for ou...
journal_title:Open forum infectious diseases
pub_type: 杂志文章
doi:10.1093/ofid/ofaa034
更新日期:2020-01-29 00:00:00
abstract::Methods. In a cross-sectional substudy of the Multicenter AIDS Cohort Study, noncontrast cardiac computed tomography (CT) scanning for coronary artery calcium (CAC) scoring was performed on all men, and, for men with normal renal function, coronary CT angiography (CTA) was performed. Associations between fat depots (...
journal_title:Open forum infectious diseases
pub_type: 杂志文章
doi:10.1093/ofid/ofw098
更新日期:2016-06-16 00:00:00
abstract:Background:Clinical features of Lyme disease (LD) range from localized skin lesions to serious disseminated disease. Information on risk factors for Lyme arthritis, facial palsy, carditis, and meningitis is limited but could facilitate disease recognition and elucidate pathophysiology. Methods:Patients from high-incid...
journal_title:Open forum infectious diseases
pub_type: 杂志文章
doi:10.1093/ofid/ofx254
更新日期:2017-11-18 00:00:00
abstract::Microvascular function and oxygen consumption affect oxygen homeostasis but have not been assessed in African children with malaria. Microvascular function in Tanzanian children with severe malaria (SM) or uncomplicated malaria were 39% and 72%, respectively, of controls (P < .001). Uncomplicated malaria (P = .04), no...
journal_title:Open forum infectious diseases
pub_type: 杂志文章
doi:10.1093/ofid/ofx079
更新日期:2017-04-22 00:00:00
abstract:Background:Hepatitis C virus (HCV), a major cause of morbidity and mortality, is common and rising among young persons who inject drugs (PWID). Reducing the level of viremia may be an intervention, yet the impact of viremia on HCV transmission is unknown. Methods:We conducted a prospective study of injecting partnersh...
journal_title:Open forum infectious diseases
pub_type: 杂志文章
doi:10.1093/ofid/ofz125
更新日期:2019-04-25 00:00:00
abstract:Background:Cytomegalovirus (CMV) mononucleosis is a manifestation of primary CMV infection. This study aims to establish the link between long-term population CMV seroepidemiological trends and incidence of CMV mononucleosis requiring hospitalization. Furthermore, by analyzing serial laboratory data of patients hospita...
journal_title:Open forum infectious diseases
pub_type: 杂志文章
doi:10.1093/ofid/ofy262
更新日期:2018-10-20 00:00:00
abstract:Background:We characterized the extent of antiretroviral therapy (ART) experience and postdischarge mortality among hospitalized HIV-infected adults in Zambia. Methods:At a central hospital with an opt-out HIV testing program, we enrolled HIV-infected adults (18+ years) admitted to internal medicine using a population...
journal_title:Open forum infectious diseases
pub_type: 杂志文章
doi:10.1093/ofid/ofz336
更新日期:2019-07-16 00:00:00
abstract::Symptomatic acute HCV infection and interferon lambda 4 (IFNL4) genotypes are important predictors of spontaneous viral clearance. Using data from a multicohort database (Injecting Cohorts [InC3] Collaborative), we establish an independent association between host IFNL4 genotype and symptoms of acute hepatitis C virus...
journal_title:Open forum infectious diseases
pub_type: 杂志文章
doi:10.1093/ofid/ofw024
更新日期:2016-02-08 00:00:00
abstract:Background:In December 2018, a large, tertiary, university-affiliated hospital in the Philippines discovered that their legitimate supply chain was infiltrated with counterfeit rabies vaccines. Methods:All vials suspected to be counterfeit were quarantined and surrendered to the Philippine Food and Drug Administration...
journal_title:Open forum infectious diseases
pub_type: 杂志文章
doi:10.1093/ofid/ofaa313
更新日期:2020-07-22 00:00:00
abstract:Background:Maintaining retention in preexposure prophylaxis (PrEP) care among diverse patient populations will be needed to support PrEP's efficacy. We characterized patterns of PrEP care retention in a US municipal primary care health network and examined whether missed visits, a metric of care retention that is easy ...
journal_title:Open forum infectious diseases
pub_type: 杂志文章
doi:10.1093/ofid/ofz101
更新日期:2019-02-26 00:00:00
abstract::Among a cohort of men who have sex with men in a pre-exposure prophylaxis (PrEP) adherence trial, syphilis requiring treatment was associated with white coat dosing (increased PrEP adherence immediately preceding study visits) when compared with participants with optimal drug concentrations. The findings highlight the...
journal_title:Open forum infectious diseases
pub_type: 杂志文章
doi:10.1093/ofid/ofaa329
更新日期:2020-08-07 00:00:00
abstract:Background:The Affordable Care Act's (ACA's) major reforms started in 2014. In addition to assessing HIV clinicians' ACA knowledge and attitudes, this study aims to evaluate HIV clinicians' perspectives on whether the ACA has impacted the quality of HIV care and whether it addresses the main barriers to HIV care. Meth...
journal_title:Open forum infectious diseases
pub_type: 杂志文章
doi:10.1093/ofid/ofaa225
更新日期:2020-06-10 00:00:00
abstract:Background:This study investigates the association of clinical and demographic predictors with abdominal fat gain, measured using waist circumference (WC) and self-reported abdominal size. Methods:We analyzed data from ACTG A5257, a clinical trial that randomized treatment-naïve HIV-infected participants to 1 of 3 ant...
journal_title:Open forum infectious diseases
pub_type: 杂志文章
doi:10.1093/ofid/ofy201
更新日期:2018-11-16 00:00:00
abstract:Background:Recent observations provide evidence for group-specific immunity toward influenza A infections and raise the question of how often we can get the flu. Methods:We retrospectively analyzed 2308 cases of children and adolescents with clinically manifested influenza and a positive PCR-test during the last 4 epi...
journal_title:Open forum infectious diseases
pub_type: 杂志文章
doi:10.1093/ofid/ofz195
更新日期:2019-04-23 00:00:00
abstract::Both dengue virus (DENV) and hepatitis C virus (HCV) belong to the Flaviviridae family and could induce hepatitis. We aimed to investigate the interference between them. In total, 515 patients confirmed with dengue fever (DF) were enrolled. Thirty-two patients (6.21%) were seropositive for anti-HCV; 12 of 32 anti-HCV-...
journal_title:Open forum infectious diseases
pub_type: 杂志文章
doi:10.1093/ofid/ofaa272
更新日期:2020-07-03 00:00:00
abstract:: Background. The mechanism of virologic failure (VF) of lopinavir/ritonavir (LPV/r) monotherapy is not well understood. We assessed sequence changes in human immunodeficiency virus-1 reverse-transcriptase (RT) and protease (PR) regions. Methods. ...
journal_title:Open forum infectious diseases
pub_type: 杂志文章
doi:10.1093/ofid/ofw154
更新日期:2016-08-24 00:00:00
abstract::We describe a case of fetal parvovirus B19 infection resulting in preterm birth and leading to hydrops fetalis requiring multiple in utero transfusions. The infant developed chronic postnatal anemia responsive to intravenous immunoglobulin therapy. Serum viral load decreased after immunoglobulin treatment but remained...
journal_title:Open forum infectious diseases
pub_type: 杂志文章
doi:10.1093/ofid/ofv049
更新日期:2015-04-15 00:00:00
abstract:Background:Kindergarten-entry vaccination requirements have played an important role in controlling vaccine-preventable diseases in the United States. Forty-eight states and the District of Colombia offer nonmedical exemptions to vaccines, ranging in stringency. Methods:We analyzed state-level exemption data from 2011...
journal_title:Open forum infectious diseases
pub_type: 杂志文章
doi:10.1093/ofid/ofx244
更新日期:2017-11-15 00:00:00
abstract::Far East scarlet-like fever (FESLF) is a severe inflammatory disease that occurs sporadically and in outbreaks in Russia and Japan. Far East scarlet-like fever is caused by Yersinia pseudotubuclosis infection, an organism that typically causes self-limiting gastroenteritis in Europe. Studies suggest the ability of Far...
journal_title:Open forum infectious diseases
pub_type: 杂志文章,评审
doi:10.1093/ofid/ofv202
更新日期:2015-12-17 00:00:00
abstract:Background:The number of invasive group A Streptococcus (iGAS) infections due to hitherto extremely rare type emm74 strains has increased in several Canadian provinces since late 2015. We hypothesized that the cases recorded in the different provinces are linked and caused by strains of an emm74 clone that recently eme...
journal_title:Open forum infectious diseases
pub_type: 杂志文章
doi:10.1093/ofid/ofy085
更新日期:2018-04-20 00:00:00
abstract:BACKGROUND:Human immunodeficiency virus (HIV)-associated neurocognitive disorders occurs in 20%-50% of HIV-positive patients. We undertook this study to assess the prevalence of a positive screen for cognitive impairment in the clinic population at our institution and to demonstrate the feasibility of implementing a sc...
journal_title:Open forum infectious diseases
pub_type: 杂志文章
doi:10.1093/ofid/ofw242
更新日期:2016-12-27 00:00:00
abstract::We treated three pediatric cardiac transplant patients with chronic parvovirus viremia with high-dose intravenous immunoglobulin (HD-IVIG). One patient with severe T-cell lymphopenia suffered recurrent viremia and aseptic meningitis, which resolved remarkably when he was switched to high-dose hyaluronidase-facilitated...
journal_title:Open forum infectious diseases
pub_type:
doi:10.1093/ofid/ofaa076
更新日期:2020-03-12 00:00:00
abstract::We report a family who acquired acute toxoplasmosis after a trip to Central America. One member developed severe clinical manifestations including bilateral chorioretinitis, hepatitis, and myocarditis requiring therapy. Symptomatic acute toxoplasmosis is unusual and possesses a diagnostic challenge. We discuss the cli...
journal_title:Open forum infectious diseases
pub_type: 杂志文章
doi:10.1093/ofid/ofy058
更新日期:2018-03-09 00:00:00