Potency and breadth of human primary ZIKV immune sera shows that Zika viruses cluster antigenically as a single serotype.

abstract：:The major arboviral diseases in mainland China include Japanese encephalitis, dengue fever, Crimean-Congo hemorrhagic fever (also known as Xinjiang hemorrhagic fever), and tick-borne encephalitis. These and other newly found arbovirus infections due to Banna virus and Tahyna virus contribute to a large and relatively ...

journal_title：PLoS neglected tropical diseases

authors： Gao X,Nasci R,Liang G

更新日期：2010-04-27 00:00:00

abstract：:The World Health Organization (WHO) defines an effective round of mass drug administration (MDA) for lymphatic filariasis (LF) as one that reaches at least 65% of the target population. In its first round of MDA in 2011-2012, the National Program to Eliminate LF in Haiti achieved a 79% epidemiological coverage in urba...

journal_title：PLoS neglected tropical diseases

authors： Wodnik BK,Louis DH,Joseph M,Wilkers LT,Landskroener SD,Desir L,Lemoine JF,Lavery JV

更新日期：2020-05-29 00:00:00

abstract：BACKGROUND:Mosquito-borne pathogens pose major public health challenges worldwide. With vaccines or effective drugs still unavailable for most such pathogens, disease prevention heavily relies on vector control. To date, however, mosquito control has proven difficult, with low breeding-site coverage during control camp...

journal_title：PLoS neglected tropical diseases

authors： Abad-Franch F,Zamora-Perea E,Ferraz G,Padilla-Torres SD,Luz SL

更新日期：2015-04-07 00:00:00

abstract：:Chikungunya virus (CHIKV) is the only causative agent of CHIKV fever with persistent arthralgia, and in some cases may lead to neurological complications which can be highly fatal, therefore it poses severe health issues in many parts of the world. CHIKV transmission can be mediated via the Aedes albopictus mosquito; ...

journal_title：PLoS neglected tropical diseases

authors： Lee RC,Chu JJ

更新日期：2015-03-04 00:00:00

abstract：BACKGROUND:Mycobacterium ulcerans disease (Buruli ulcer) is the most widespread mycobacterial disease in the world after leprosy and tuberculosis. How M. ulcerans is introduced into the skin of humans remains unclear, but it appears that individuals living in the same environment may have different susceptibilities. O...

journal_title：PLoS neglected tropical diseases

authors： Sopoh GE,Barogui YT,Johnson RC,Dossou AD,Makoutodé M,Anagonou SY,Kestens L,Portaels F

更新日期：2010-07-13 00:00:00

abstract：BACKGROUND:Incidence of Entamoeba histolytica infection and clinical manifestations and treatment response of invasive amebiasis (IA) in HIV-infected patients have rarely been investigated before. METHODOLOGY/PRINCIPAL FINDINGS:At the National Taiwan University Hospital, medical records of HIV-infected patients who re...

journal_title：PLoS neglected tropical diseases

authors： Hung CC,Ji DD,Sun HY,Lee YT,Hsu SY,Chang SY,Wu CH,Chan YH,Hsiao CF,Liu WC,Colebunders R

更新日期：2008-02-27 00:00:00

abstract：:[This corrects the article DOI: 10.1371/journal.pntd.0004223.]. ...

journal_title：PLoS neglected tropical diseases

authors： Wardrop NA,Thomas LF,Atkinson PM,de Glanville WA,Cook EA,Wamae CN,Gabriël S,Dorny P,Harrison LJ,Fèvre EM

更新日期：2016-01-13 00:00:00

abstract：:In this communication, a case of black grain eumycetoma produced by the fungus C. atrobrunneum is reported. The patient was initially misdiagnosed with M. mycetomatis eumycetoma based on the grains' morphological and cytological features. However, further aerobic culture of the black grains generated a melanised fungu...

journal_title：PLoS neglected tropical diseases

authors： Mhmoud NA,Santona A,Fiamma M,Siddig EE,Deligios M,Bakhiet SM,Rubino S,Fahal AH

更新日期：2019-05-30 00:00:00

abstract：BACKGROUND:Severe fever with thrombocytopenia syndrome virus (SFTSV), the causative agent for the fatal life-threatening infectious disease, severe fever with thrombocytopenia syndrome (SFTS), was first identified in the central and eastern regions of China. Although the viral RNA was detected in free-living and parasi...

journal_title：PLoS neglected tropical diseases

authors： Jiao Y,Qi X,Liu D,Zeng X,Han Y,Guo X,Shi Z,Wang H,Zhou M

更新日期：2015-10-20 00:00:00

abstract：BACKGROUND:Leptospirosis is an emerging zoonosis that is often under-recognized in children and commonly confused with dengue in tropical settings. An enhanced ability to distinguish leptospirosis from dengue in children would guide clinicians and public health personnel in the appropriate use of limited healthcare res...

journal_title：PLoS neglected tropical diseases

authors： Libraty DH,Myint KS,Murray CK,Gibbons RV,Mammen MP,Endy TP,Li W,Vaughn DW,Nisalak A,Kalayanarooj S,Hospenthal DR,Green S,Rothman AL,Ennis FA

更新日期：2007-12-26 00:00:00

abstract：BACKGROUND:Treatment needs for Schistosoma haematobium are commonly evaluated using urine filtration with detection of parasite eggs under a microscope. A common symptom of S. haematobium is hematuria, the passing of blood in urine. Hence, the use of hematuria-based diagnostic techniques as a proxy for the assessment o...

journal_title：PLoS neglected tropical diseases

authors： Midzi N,Bärenbold O,Manangazira P,Phiri I,Mutsaka-Makuvaza MJ,Mhlanga G,Utzinger J,Vounatsou P

更新日期：2020-08-20 00:00:00

abstract：:Visceral leishmaniasis is hypoendemic in Mediterranean countries, where it is caused by the flagellate protozoan Leishmania infantum. VL cases in this area account for 5%-6% of the global burden. Cases of Leishmania/HIV coinfection have been reported in the Mediterranean region, mainly in France, Italy, Portugal, and ...

journal_title：PLoS neglected tropical diseases

authors： Monge-Maillo B,Norman FF,Cruz I,Alvar J,López-Vélez R

更新日期：2014-08-21 00:00:00

abstract：:Hand, foot and mouth disease (HFMD) continues to challenge Asia with pandemic potential. In Vietnam, there have been two major outbreaks occurring during 2011-2012 (>200,000 hospitalizations and >200 deaths) and more recently in 2018 (>130,000 hospitalizations and 17 deaths). Given the high burden and the complex epid...

journal_title：PLoS neglected tropical diseases

authors： Nhan LNT,Khanh TH,Hong NTT,Van HMT,Nhu LNT,Ny NTH,Nguyet LA,Thanh TT,Anh NT,Hang VTT,Qui PT,Viet HL,Tung TH,Ha DQ,Tuan HM,Thwaites G,Chau NVV,Thwaites L,Hung NT,van Doorn HR,Tan LV

更新日期：2020-08-17 00:00:00

abstract：:The vast burden of cryptococcal meningitis occurs in immunosuppressed patients, driven by HIV, and is caused by Cryptococcus neoformans var. grubii. We previously reported cryptococcal meningitis in Vietnam arising atypically in HIV uninfected, apparently immunocompetent patients, caused by a single amplified fragment...

journal_title：PLoS neglected tropical diseases

authors： Day JN,Qihui S,Thanh LT,Trieu PH,Van AD,Thu NH,Chau TTH,Lan NPH,Chau NVV,Ashton PM,Thwaites GE,Boni MF,Wolbers M,Nagarajan N,Tan PBO,Baker S

更新日期：2017-06-14 00:00:00

abstract：:Between March 2014 and July 2015 at least 10,500 Ebola cases including more than 4,800 deaths occurred in Liberia, the majority in Monrovia. However, official numbers may have underestimated the size of the outbreak. Closure of health facilities and mistrust in existing structures may have additionally impacted on all...

journal_title：PLoS neglected tropical diseases

authors： Kuehne A,Lynch E,Marshall E,Tiffany A,Alley I,Bawo L,Massaquoi M,Lodesani C,Le Vaillant P,Porten K,Gignoux E

更新日期：2016-08-23 00:00:00

abstract：BACKGROUND:Little information is available about infantile visceral leishmaniasis (VL) in Albania as regards incidence, diagnosis and management of the disease. METHODOLOGY/PRINCIPAL FINDINGS:Demographic data, clinical and laboratory features and therapeutic findings were considered in children admitted to University ...

journal_title：PLoS neglected tropical diseases

authors： Petrela R,Kuneshka L,Foto E,Zavalani F,Gradoni L

更新日期：2010-09-07 00:00:00

abstract：:We evaluated the protection conferred by a first documented visit for clinical care of typhoid fever against recurrent typhoid fever prompting a visit. This study takes advantage of multi-year follow-up of a population with endemic typhoid participating in a cluster-randomized control trial of Vi capsular polysacchari...

journal_title：PLoS neglected tropical diseases

authors： Im J,Islam MT,Kim DR,Ahmmed F,Chon Y,Zaman K,Khan AI,Ali M,Sur D,Kanungo S,Dutta S,Bhattacharya SK,Dougan G,Holt KE,Marks F,Kim JH,Qadri F,Clemens JD

更新日期：2020-08-17 00:00:00

abstract：BACKGROUND:Echinococcosis is a life-threatening parasitic disease caused by Echinococcus spp. tapeworms with over one million people affected globally at any time. The Echinococcus spp. tapeworms in the human body release DNA to the circulatory system, which can be a biomarker for echinococcosis. Cell-free DNA (cfDNA) ...

journal_title：PLoS neglected tropical diseases

authors： Ji J,Li B,Li J,Danzeng W,Li J,Zhao Y,Qiangba G,Zhang Q,Renzhen N,Basang Z,Jia C,Gongsang Q,Ma J,Wang Y,Chen F,Zhou H,Huasang,Yin J,Xie J,Pei N,Cai H,Jiang H,Yang H,Wang J,Asan,Han X,Li J,Chen W,Yan

更新日期：2020-04-13 00:00:00

abstract：:Two recombinant Fasciola hepatica antigens, saposin-like protein-2 (recSAP2) and cathepsin L-1 (recCL1), were assessed individually and in combination in enzyme-linked immunosorbent assays (ELISA) for the specific serodiagnosis of human fasciolosis in areas of low endemicity as encountered in Central Europe. Antibody ...

journal_title：PLoS neglected tropical diseases

authors： Gottstein B,Schneeberger M,Boubaker G,Merkle B,Huber C,Spiliotis M,Müller N,Garate T,Doherr MG

更新日期：2014-06-12 00:00:00

abstract：BACKGROUND:During the 2014-2016 West Africa Ebola Virus Disease (EVD) epidemic, the public health community had concerns that sexual transmission of the Ebola virus (EBOV) from EVD survivors was a risk, due to EBOV persistence in body fluids of EVD survivors, particularly semen. The Sierra Leone Ebola Virus Persistence...

journal_title：PLoS neglected tropical diseases

authors： Abad N,Malik T,Ariyarajah A,Ongpin P,Hogben M,McDonald SLR,Marrinan J,Massaquoi T,Thorson A,Ervin E,Bernstein K,Ross C,Liu WJ,Kroeger K,Durski KN,Broutet N,Knust B,Deen GF,Sierra Leone Ebola Virus Persistence Study Gr

更新日期：2017-09-11 00:00:00

abstract：BACKGROUND:Hantaan virus (HTNV; family Hantaviridae, order Bunyavirales) causes hemorrhagic fever with renal syndrome (HFRS), which has raised serious concerns in Eurasia, especially in China, Russia, and South Korea. Previous studies reported genetic diversity and phylogenetic features of HTNV in different parts of Ch...

journal_title：PLoS neglected tropical diseases

authors： Li N,Li A,Liu Y,Wu W,Li C,Yu D,Zhu Y,Li J,Li D,Wang S,Liang M

更新日期：2020-08-20 00:00:00

abstract：:In Côte d'Ivoire, rabies is endemic and remains largely uncontrolled. The numbers of human exposures and rabies cases are unknown and are probably much higher than reported. Data on human rabies cases are collected by the National Institute of Public Health (NIPH) Anti-rabies Center in Abidjan through a network of 28 ...

journal_title：PLoS neglected tropical diseases

authors： Tiembré I,Broban A,Bénié J,Tetchi M,Druelles S,L'Azou M

更新日期：2018-09-06 00:00:00

abstract：:Schistosomiasis is a parasitic disease and its distribution, in space and time, can be influenced by environmental factors such as rivers, elevation, slope, land surface temperature, land use/cover and rainfall. The aim of this study is to identify the areas with suitable conditions for schistosomiasis transmission on...

journal_title：PLoS neglected tropical diseases

authors： Ajakaye OG,Adedeji OI,Ajayi PO

更新日期：2017-07-12 00:00:00

abstract：BACKGROUND:Paracoccidioides brasiliensis causes paracoccidioidomycosis, one of the most prevalent systemic mycosis in Latin America. Thus, understanding the characteristics of the protective immune response to P. brasiliensis is of interest, as it may reveal targets for disease control. The initiation of the immune res...

journal_title：PLoS neglected tropical diseases

authors： Menino JF,Saraiva M,Gomes-Alves AG,Lobo-Silva D,Sturme M,Gomes-Rezende J,Saraiva AL,Goldman GH,Cunha C,Carvalho A,Romani L,Pedrosa J,Castro AG,Rodrigues F

更新日期：2013-07-25 00:00:00

abstract：INTRODUCTION:Previous studies of Ebola Virus Disease (EVD) have focused on clinical symptoms and Ebola virus (EBOV) cycle threshold (CT) values recorded at patient triage. Our study explores EVD symptoms and EBOV CT values from onset of illness to recovery or death in a diverse population of patients. METHODOLOGY/PRIN...

journal_title：PLoS neglected tropical diseases

authors： Skrable K,Roshania R,Mallow M,Wolfman V,Siakor M,Levine AC

更新日期：2017-07-19 00:00:00

abstract：BACKGROUND:Schistosomiasis japonica is a zoonotic parasitic disease. After nearly 70 years of control efforts in China, Schistosomiasis transmission has been reduced to a much lower level. The absence or near absence of infections in humans or livestock, based on traditional fecal and serological tests, has made the ta...

journal_title：PLoS neglected tropical diseases

authors： Qiu C,Zou HY,Deng Y,Liang YS,Lu DB

更新日期：2019-06-07 00:00:00

abstract：BACKGROUND:Typhoid fever, caused by the Gram-negative bacterium Salmonella enterica serovar Typhi, is a major cause of community-acquired bacteremia and death worldwide. S100A8 (MRP8) and S100A9 (MRP14) form bioactive antimicrobial heterodimers (calprotectin) that can activate Toll-like receptor 4, promoting lethal, en...

journal_title：PLoS neglected tropical diseases

authors： De Jong HK,Achouiti A,Koh GC,Parry CM,Baker S,Faiz MA,van Dissel JT,Vollaard AM,van Leeuwen EM,Roelofs JJ,de Vos AF,Roth J,van der Poll T,Vogl T,Wiersinga WJ

更新日期：2015-04-10 00:00:00

abstract：BACKGROUND:Since its beginning in 1999, the Schistosomiasis Control Program within the Unified Health System (PCE-SUS) has registered a cumulative coverage of just 20% of the population from the Rainforest Zone of Pernambuco (ZMP), northeast Brazil. This jeopardizes the accomplishment of the minimum goal of the Fifty-F...

journal_title：PLoS neglected tropical diseases

authors： Favre TC,Pereira AP,Galvão AF,Zani LC,Barbosa CS,Pieri OS

更新日期：2009-01-01 00:00:00

abstract：:Bat rabies is an emerging disease of public health significance in the Americas. The Caribbean island of Trinidad experiences periodic outbreaks within the livestock population. We performed molecular characterisation of Trinidad rabies virus (RABV) and used a Bayesian phylogeographic approach to investigate the exten...

journal_title：PLoS neglected tropical diseases

authors： Seetahal JF,Velasco-Villa A,Allicock OM,Adesiyun AA,Bissessar J,Amour K,Phillip-Hosein A,Marston DA,McElhinney LM,Shi M,Wharwood CA,Fooks AR,Carrington CV

更新日期：2013-08-22 00:00:00

abstract：BACKGROUND:Rhinoentomophthoromycosis, or rhino-facial conidiobolomycosis, is a rare, grossly disfiguring disease due to an infection with entomophthoralean fungi. We report a case of rhinoentomophthoromycosis from Gabon and suggest a staging system, which provides information on the prognosis and duration of antifungal...

journal_title：PLoS neglected tropical diseases

authors： Blumentrath CG,Grobusch MP,Matsiégui PB,Pahlke F,Zoleko-Manego R,Nzenze-Aféne S,Mabicka B,Sanguinetti M,Kremsner PG,Schaumburg F

更新日期：2015-10-01 00:00:00