OTUD6B-AS1 Inhibits Viability, Migration, and Invasion of Thyroid Carcinoma by Targeting miR-183-5p and miR-21.

abstract：:Many patients with type 1 diabetes (T1D) do not achieve the glycemic target goal with insulin treatment. In this study, we aimed to evaluate the efficacy and safety of add-on to insulin therapy in patients with T1D. We conducted direct and indirect network meta-analyses using Bayesian models and ranked hypoglycemic ag...

journal_title：Frontiers in endocrinology

authors： Kim YJ,Hwang SD,Lim S

更新日期：2020-08-19 00:00:00

abstract：:Kisspeptin, encoded by the Kiss1 gene, is required for reproduction. Humans and mice lacking kisspeptin or its receptor, Kiss1r, have impairments in reproductive physiology and fertility. In addition to being located in the hypothalamus in the anteroventral periventricular and arcuate nuclei, kisspeptin neurons are al...

journal_title：Frontiers in endocrinology

authors： Stephens SBZ,Kauffman AS

更新日期：2017-08-07 00:00:00

abstract：:At least 57 independent loci within the human genome confer varying degrees of risk for the development of type 1 diabetes (T1D). The majority of these variants are thought to contribute to overall genetic risk by modulating host innate and adaptive immune responses, ultimately resulting in a loss of immunological tol...

journal_title：Frontiers in endocrinology

authors： Wallet MA,Santostefano KE,Terada N,Brusko TM

更新日期：2017-10-18 00:00:00

abstract：:Introduction: Follicular-derived differentiated thyroid carcinoma (DTC) is the most common endocrine and epithelial malignancy in children. The differences in the clinical and pathological features of pediatric vs. adult DTC could relate to a different genetic profile. Few studies are currently available in this issue...

journal_title：Frontiers in endocrinology

authors： Galuppini F,Vianello F,Censi S,Barollo S,Bertazza L,Carducci S,Colato C,Manso J,Rugge M,Iacobone M,Watutantrige Fernando S,Pennelli G,Mian C

更新日期：2019-08-07 00:00:00

abstract：:Maternal over-nutrition can lead to metabolic disorders in offspring, whereas maternal dietary genistein may have beneficial effects on the metabolic health of offspring. Our objective was to determine whether maternal dietary genistein could attenuate the detrimental effects of a maternal high-fat diet on their offsp...

journal_title：Frontiers in endocrinology

authors： Zhou L,Xiao X,Zhang Q,Zheng J,Li M,Yu M,Wang X,Deng M,Zhai X,Li R

更新日期：2018-09-04 00:00:00

abstract：:Previous work has shown that reduced expression of PLCXD3, a member of the phosphoinositide-specific phospholipases (PI-PLC) family, impaired insulin secretion with an unclear mechanism. In the current study, we aim to investigate the mechanism underlying this effect using human islets and rat INS-1 (832/13) cells. Mi...

journal_title：Frontiers in endocrinology

authors： Aljaibeji H,Mukhopadhyay D,Mohammed AK,Dhaiban S,Hachim MY,Elemam NM,Sulaiman N,Salehi A,Taneera J

更新日期：2019-11-06 00:00:00

abstract：BACKGROUND:Monitoring blood levels of human growth hormone (hGH) in most children with short stature deficiencies is crucial for taking a decision of treatment with extended course of daily and expensive doses of recombinant hGH (rhGH or Somatropin®). Besides, misusing of rhGH by sportsmen is banned by the World Anti-D...

journal_title：Frontiers in endocrinology

authors： Murad H,Assaad JM,Al-Shemali R,Abbady AQ

更新日期：2017-05-30 00:00:00

abstract：:The brain is composed of neurons and non-neuronal cells, with the latter encompassing glial, ependymal and endothelial cells, as well as pericytes and progenitor cells. Studies aimed at understanding how the brain operates have traditionally focused on neurons, but the importance of non-neuronal cells has become incre...

journal_title：Frontiers in endocrinology

authors： Argente-Arizón P,Freire-Regatillo A,Argente J,Chowen JA

更新日期：2015-03-26 00:00:00

abstract：Background:Left ventricular (LV) diastolic dysfunction has been demonstrated to be an independent predictor of the future heart failure. Heart failure is one of the severe complications caused by overt hyperthyroidism. However, the effects of overt hyperthyroidism on diastolic dysfunction are conflicting, and little is...

journal_title：Frontiers in endocrinology

authors： Li H,Zeng R,Liao Y,Fu M,Zhang H,Wang L,Li Y

更新日期：2021-01-08 00:00:00

abstract：:Obstructive sleep apnea-hypopnea syndrome (OSAHS) is frequently present in patients with severe obesity, but its prevalence especially in women is not well defined. OSAHS and non-alcoholic fatty liver disease are common conditions, frequently associated in patients with central obesity and metabolic syndrome and are b...

journal_title：Frontiers in endocrinology

authors： Scartabelli G,Querci G,Marconi L,Ceccarini G,Piaggi P,Fierabracci P,Salvetti G,Cizza G,Mazzeo S,Vitti J,Berger S,Palla A,Santini F

更新日期：2018-06-06 00:00:00

abstract：:Anti-Müllerian hormone reflects the continuum of the functional ovarian reserve, and as such can predict ovarian response to gonadotropin stimulation and be used to individualize treatment pathways to improve efficacy and safety. However, consistent with other biomarkers and age-based prediction models it has limited ...

journal_title：Frontiers in endocrinology

authors： Li HWR,Nelson SM

更新日期：2020-12-09 00:00:00

abstract：:[This corrects the article on p. 26 in vol. 9, PMID: 29487564.]. ...

journal_title：Frontiers in endocrinology

authors： Konya J,Spurgeon BEJ,Al Qaissi A,Sathyapalan T,Ajjan R,Madden L,Naseem KM,Garrett AT,Kilpatrick E,Atkin SL

更新日期：2018-06-07 00:00:00

abstract：Background:Renal function is profoundly influenced by thyroid hormone levels. This study was designed to evaluate the association between preoperative thyroid hormones and postoperative acute kidney injury (AKI) in acute type A aortic dissection (ATAAD) patients. Methods:A total of 88 patients with ATAAD who underwent...

journal_title：Frontiers in endocrinology

authors： Liu J,Xue Y,Jiang W,Zhang H,Zhao Y

更新日期：2020-11-18 00:00:00

abstract：:Background: In the past decade, continuous glucose monitoring (CGM) has been proven to have similar accuracy to self-monitoring of blood glucose (SMBG) and yet provides better therapy optimization and detects trends in glucose values due to higher frequency of testing. Even though the feasibility and utility of CGM ha...

journal_title：Frontiers in endocrinology

authors： Yu Q,Aris IM,Tan KH,Li LJ

更新日期：2019-10-11 00:00:00

abstract：:G protein-coupled estrogen receptor (GPER) in the amygdala and the dorsal hippocampus mediates actions of estradiol on anxiety, social recognition and spatial memory. In addition, GPER participates in the estrogenic regulation of synaptic function in the amygdala and in the process of adult neurogenesis in the dentate...

journal_title：Frontiers in endocrinology

authors： Llorente R,Marraudino M,Carrillo B,Bonaldo B,Simon-Areces J,Abellanas-Pérez P,Rivero-Aguilar M,Fernandez-Garcia JM,Pinos H,Garcia-Segura LM,Collado P,Grassi D

更新日期：2020-08-07 00:00:00

abstract：:Pituitary adenomas, accounting for 15% of diagnosed intracranial neoplasms, are usually benign and pharmacologically and surgically treatable; however, the critical location, mass effects and hormone hypersecretion sustain their significant morbidity. Approximately 35% of pituitary tumors show a less benign course sin...

journal_title：Frontiers in endocrinology

authors： Würth R,Thellung S,Corsaro A,Barbieri F,Florio T

更新日期：2020-02-20 00:00:00

abstract：:Background: Insulin plays a pivotal role in the regulation of both carbohydrate and lipid intermediate turnover and metabolism. In the transition from a fasted to fed state, insulin action inhibits lipolysis in adipocytes, and acylcarnitine synthesis in the muscles and heart. The aim of this study was to measure free ...

journal_title：Frontiers in endocrinology

authors： Makarova E,Makrecka-Kuka M,Vilks K,Volska K,Sevostjanovs E,Grinberga S,Zarkova-Malkova O,Dambrova M,Liepinsh E

更新日期：2019-12-17 00:00:00

abstract：:Background: Consistent evidence have demonstrated that patients with primary aldosteronism (PA) have higher risk of cardiovascular events to patients with essential hypertension (EH). Whether the long-term risk of mortality for PA patients is higher than EH patients is unclear. We aim to compare the long-term mortalit...

journal_title：Frontiers in endocrinology

authors： Meng Z,Dai Z,Huang K,Xu C,Zhang YG,Zheng H,Liu TZ

更新日期：2020-03-10 00:00:00

abstract：:[This corrects the article DOI: 10.3389/fendo.2018.00031.]. ...

journal_title：Frontiers in endocrinology

authors： Beattie J,Al-Khafaji H,Noer PR,Alkharobi HE,Alhodhodi A,Meade J,El-Gendy R,Oxvig C

更新日期：2018-09-04 00:00:00

abstract：:[This corrects the article on p. 162 in vol. 6, PMID: 26528241.]. ...

journal_title：Frontiers in endocrinology

authors： Frontiers Production Office.

更新日期：2015-11-16 00:00:00

abstract：:JAK2 is a member of the Janus kinase (JAKs) family of non-receptor protein tyrosine kinases, which includes JAK1-3 and TYK2. JAKs serve as the cytoplasmic signaling components of cytokine receptors and are activated through cytokine-mediated trans-phosphorylation, which leads to receptor phosphorylation and recruitmen...

journal_title：Frontiers in endocrinology

authors： Hubbard SR

更新日期：2018-01-05 00:00:00

abstract：:Prostate cancer (PCa) is the major cause of cancer-related death among the male population of Western society, and androgen-deprivation therapy (ADT) represents the first line in PCa treatment. However, although androgen receptor (AR) expression is maintained throughout the various stages of PCa, ADT frequently fails....

journal_title：Frontiers in endocrinology

authors： Di Donato M,Giovannelli P,Cernera G,Di Santi A,Marino I,Bilancio A,Galasso G,Auricchio F,Migliaccio A,Castoria G

更新日期：2015-01-19 00:00:00

abstract：:Over the past decade, the increasing prevalence of obesity and its associated metabolic disorders constitutes one of the most concerning healthcare issues for countries worldwide. In an effort to curb the increased mortality and morbidity derived from the obesity epidemic, various therapeutic strategies have been deve...

journal_title：Frontiers in endocrinology

authors： Ong BX,Brunmeir R,Zhang Q,Peng X,Idris M,Liu C,Xu F

更新日期：2020-02-27 00:00:00

abstract：:There is increasing evidence supporting the characterization of the pesticide DDT and its metabolite, DDE, as obesogens and metabolic disruptors. Elucidating the mechanism is critical to understanding whether the association of DDT and DDE with obesity and diabetes is in fact causal. One area of research investigating...

journal_title：Frontiers in endocrinology

authors： Elmore SE,La Merrill MA

更新日期：2019-03-12 00:00:00

abstract：:Measuring salivary cortisol is both convenient and non-invasive for patients; however, its usefulness as a marker for monitoring medical therapy has not yet been established. The aim of this study was to assess the utility of multiple salivary cortisol measurements in patients with Cushing's syndrome (CS) during medic...

journal_title：Frontiers in endocrinology

authors： Yoshida K,Fukuoka H,Odake Y,Nakajima S,Tachibana M,Ito J,Hosokawa Y,Yamada T,Miura H,Suematsu N,Matsumoto R,Bando H,Suda K,Nishizawa H,Iguchi G,Ogawa W,Takahashi Y

更新日期：2018-01-11 00:00:00

abstract：:Insulin resistance (IR) is a pathological condition strongly associated with obesity. However, corticosteroids or growth hormone therapy and genetic diseases may affect insulin sensitivity lifelong. In obese children and adolescents of any age there is an evident association between IR and an increased prevalence of t...

journal_title：Frontiers in endocrinology

authors： Tagi VM,Giannini C,Chiarelli F

更新日期：2019-06-04 00:00:00

abstract：:Chemokines are small molecules that play a crucial role as chemoattractants for several cell types, and their components are associated with host immune responses and repair mechanisms. Chemokines selectively recruit monocytes, neutrophils, and lymphocytes and induce chemotaxis through the activation of G protein-coup...

journal_title：Frontiers in endocrinology

authors： Siddiqui JA,Partridge NC

更新日期：2017-03-29 00:00:00

abstract：:Insulin-like growth factor-binding proteins (IGFBPs) are multifunctional proteins that possess IGF-dependent and -independent actions. Recent studies suggest that its IGF-independent action appeared early and that the IGF-binding function may have been acquired later in evolution. The timing of the emergence of IGF-de...

journal_title：Frontiers in endocrinology

authors： Zhong Y,Duan C

更新日期：2017-01-18 00:00:00

abstract：:Background: Amiodarone-induced thyrotoxicosis (AIT) is associated with significant morbidity and mortality, particularly in patients with cardiac failure. The aim of the study was to evaluate the management of AIT at a tertiary hospital specialising in cardiac failure and transplantation. Methods: Retrospective audit ...

journal_title：Frontiers in endocrinology

authors： Isaacs M,Costin M,Bova R,Barrett HL,Heffernan D,Samaras K,Greenfield JR

更新日期：2018-08-22 00:00:00

abstract：:Giant pandas represent one of the most endangered species worldwide, and their reproductive capacity is extremely low. They have a relatively long gestational period, mainly because embryo implantation is delayed. Giant panda cubs comprise only a small proportion of the mother's body weight, making it difficult to det...

journal_title：Frontiers in endocrinology

authors： Cao M,Li C,Liu Y,Cai K,Chen L,Yuan C,Zhao Z,Zhang B,Hou R,Zhou X

更新日期：2020-04-16 00:00:00