Addressing the Disease Burden of Vertically Acquired Hepatitis C Virus Infection Among Opioid-Exposed Infants.

abstract：Background:Clinical features of Lyme disease (LD) range from localized skin lesions to serious disseminated disease. Information on risk factors for Lyme arthritis, facial palsy, carditis, and meningitis is limited but could facilitate disease recognition and elucidate pathophysiology. Methods:Patients from high-incid...

journal_title：Open forum infectious diseases

authors： Kwit NA,Nelson CA,Max R,Mead PS

更新日期：2017-11-18 00:00:00

abstract：Background:Mismanagement of asymptomatic patients with positive urine cultures (referred to as asymptomatic bacteriuria [ASB] in the literature) promotes antimicrobial resistance and results in unnecessary antimicrobial-related adverse events and increased health care costs. Methods:We conducted a systematic review an...

journal_title：Open forum infectious diseases

authors： Flokas ME,Andreatos N,Alevizakos M,Kalbasi A,Onur P,Mylonakis E

更新日期：2017-11-20 00:00:00

abstract：Background:Few studies have investigated predictors of serological response to syphilis treatment in people living with HIV (PLWH). Methods:This was a retrospective, longitudinal study on PLWH who were diagnosed with and treated for syphilis who had an assessable serological response between January 2004 and June 2016...

journal_title：Open forum infectious diseases

authors： Spagnuolo V,Poli A,Galli L,Nozza S,Bossolasco S,Cernuschi M,Maillard M,Hasson H,Gianotti N,Guffanti M,Lazzarin A,Castagna A

更新日期：2018-11-30 00:00:00

abstract：:Background.  Sepsis is a major cause of morbidity and mortality among older adults. The main goals of this study were to assess the association of sepsis at intensive care unit (ICU) admission with mortality and to identify predictors associated with increased mortality in older adults. Methods.  We conducted a prospe...

journal_title：Open forum infectious diseases

authors： Rowe T,Araujo KL,Van Ness PH,Pisani MA,Juthani-Mehta M

更新日期：2016-01-21 00:00:00

abstract：: Background.  The mechanism of virologic failure (VF) of lopinavir/ritonavir (LPV/r) monotherapy is not well understood. We assessed sequence changes in human immunodeficiency virus-1 reverse-transcriptase (RT) and protease (PR) regions. Methods. ...

journal_title：Open forum infectious diseases

authors： Vardhanabhuti S,Katzenstein D,Bartlett J,Kumarasamy N,Wallis CL

更新日期：2016-08-24 00:00:00

abstract：:Interpretive criteria for in vitro susceptibility testing criteria, "susceptibility breakpoints," underpin the evaluation and selection of antimicrobial regimens. However, despite their strengths, susceptibility breakpoints are a relatively blunt instrument employed to address an extremely complex question-what is the...

journal_title：Open forum infectious diseases

authors： Bader JC,Lakota EA,Andes DR,Rubino CM,Ambrose PG,Bhavnani SM

更新日期：2018-10-31 00:00:00

abstract：:Far East scarlet-like fever (FESLF) is a severe inflammatory disease that occurs sporadically and in outbreaks in Russia and Japan. Far East scarlet-like fever is caused by Yersinia pseudotubuclosis infection, an organism that typically causes self-limiting gastroenteritis in Europe. Studies suggest the ability of Far...

journal_title：Open forum infectious diseases

authors： Amphlett A

更新日期：2015-12-17 00:00:00

abstract：Background:Pharmacists with residency training in infectious diseases (ID) optimize antimicrobial therapy outcomes in patients and support antimicrobial stewardship (AS) programs. Although most ID residencies are accredited and assessed by certain standards, the degree to which these programs are similar is not known. ...

journal_title：Open forum infectious diseases

authors： Cho JC,Crotty MP,Kufel WD,Chahine EB,Sofjan AK,Gallagher JC,Estrada SJ

更新日期：2019-09-06 00:00:00

abstract：:We report a family who acquired acute toxoplasmosis after a trip to Central America. One member developed severe clinical manifestations including bilateral chorioretinitis, hepatitis, and myocarditis requiring therapy. Symptomatic acute toxoplasmosis is unusual and possesses a diagnostic challenge. We discuss the cli...

journal_title：Open forum infectious diseases

authors： Henao-Martínez AF,Franco-Paredes C,Palestine AG,Montoya JG

更新日期：2018-03-09 00:00:00

abstract：:The potential for transmission of severe acute respiratory syndrome coronavirus 2 shed in stool via fecal microbiota transplantation is not yet known, and the effectiveness of various testing strategies to prevent fecal microbiota transplantation-based transmission has also not yet been quantified. In this study, we u...

journal_title：Open forum infectious diseases

authors： Olesen SW,Zaman A,Osman M,Ramakrishna B

更新日期：2020-10-19 00:00:00

abstract：Background:Concomitant dosing of ledipasvir (LDV) and tenofovir disoproxil fumarate (TDF) results in an increased tenofovir (TFV) area under the curve (AUC). The aim of this study was to examine whether there was a correlation between the renal biomarkers retinol binding protein-4 (RBP-4) and β2 microglobulin (β2M) and...

journal_title：Open forum infectious diseases

authors： Chan A,Park L,Collins LF,Cooper C,Saag M,Dieterich D,Sulkowski M,Naggie S

更新日期：2019-01-24 00:00:00

abstract：:Background.  Advanced fibrosis occurs more commonly in human immunodeficiency virus (HIV)-hepatitis B virus (HBV) coinfected individuals; therefore, fibrosis monitoring is important in this population. However, transient elastography (TE) data in HIV-HBV coinfection are lacking. We aimed to assess liver fibrosis using...

journal_title：Open forum infectious diseases

authors： Audsley J,Robson C,Aitchison S,Matthews GV,Iser D,Sasadeusz J,Lewin SR

更新日期：2016-02-12 00:00:00

abstract：BACKGROUND:Infection causes 1 of every 5 neonatal deaths globally. Group B Streptococcus (GBS) is the most significant pathogen, although little is known about its epidemiology and risk in low-income countries. METHODS:A cross-sectional study in 2015 at a public hospital in Guatemala City enrolled women ≥35 weeks' ges...

journal_title：Open forum infectious diseases

authors： Rick AM,Aguilar A,Cortes R,Gordillo R,Melgar M,Samayoa-Reyes G,Frank DN,Asturias EJ

更新日期：2017-02-08 00:00:00

abstract：BACKGROUND:Avian influenza A/H5N1 has threatened human health for nearly 2 decades. Avian influenza A vaccine without adjuvant is poorly immunogenic. A flexible rapid tactic for mass vaccination will be needed if a pandemic occurs. METHODS:A multicenter, randomized, blinded phase 1 clinical trial evaluated safety and ...

journal_title：Open forum infectious diseases

authors： Mulligan MJ,Bernstein DI,Frey S,Winokur P,Rouphael N,Dickey M,Edupuganti S,Spearman P,Anderson E,Graham I,Noah DL,Mangal B,Kim S,Hill H,Whitaker J,Emery W,Beck A,Stephens K,Hartwell B,Ogilvie M,Rimann N,Osinski

更新日期：2014-11-18 00:00:00

abstract：:Microvascular function and oxygen consumption affect oxygen homeostasis but have not been assessed in African children with malaria. Microvascular function in Tanzanian children with severe malaria (SM) or uncomplicated malaria were 39% and 72%, respectively, of controls (P < .001). Uncomplicated malaria (P = .04), no...

journal_title：Open forum infectious diseases

authors： Yeo TW,Florence SM,Kalingonji AR,Chen Y,Granger DL,Anstey NM,Mwaikambo ED,Weinberg JB

更新日期：2017-04-22 00:00:00

abstract：Background:Residual monocyte activation may contribute to increased risk for endothelial dysfunction and subsequent atherosclerotic cardiovascular diseases (CVDs) among people with HIV (PWH) on antiretroviral therapy (ART). We examined the relationship between monocyte activation and endothelial activation in PWH in Ke...

journal_title：Open forum infectious diseases

authors： Temu TM,Polyak SJ,Zifodya JS,Wanjalla CN,Koethe JR,Masyuko S,Nyabiage J,Kinuthia J,Gervassi AL,Oyugi J,Page S,Farquhar C

更新日期：2020-09-12 00:00:00

abstract：:Community-onset bacteremic Acinetobacter baumannii pneumonia recurred in 3 of 30 (10%) patients followed prospectively, all with ongoing hazardous alcohol intake, 3-56 months after initial pneumonia. Paired isolates underwent whole-genome sequencing. Phylogenetic analysis showed that recurrence strains were all distin...

journal_title：Open forum infectious diseases

authors： Meumann EM,Anstey NM,Currie BJ,Piera KA,Baird R,Sarovich DS,Davis JS

更新日期：2019-06-01 00:00:00

abstract：:Respiratory syncytial virus (RSV) is an increasingly recognized cause of acute respiratory infection (ARI) in adults. We compared the crude in-hospital mortality of patients with RSV infection alone with that of patients with RSV-bacterial coinfection. Overall, 12 144 hospitalized patients with ARI were screened for R...

journal_title：Open forum infectious diseases

authors： Godefroy R,Giraud-Gatineau A,Jimeno MT,Edouard S,Meddeb L,Zandotti C,Chaudet H,Colson P,Raoult D,Cassir N

更新日期：2020-11-12 00:00:00

abstract：:Elimination of a rifamycin from the treatment regimen for tuberculosis negatively impacts outcomes. Cross-reactivity between the rifamycins after drug eruptions is unclear. We report 6 consecutive human immunodeficiency virus-infected patients with rifampicin-associated drug rash with eosinophilia and systemic symptom...

journal_title：Open forum infectious diseases

authors： Lehloenya RJ,Dlamini S,Muloiwa R,Kakande B,Ngwanya MR,Todd G,Dheda K

更新日期：2016-06-20 00:00:00

abstract：:Background.  The majority of Lyme disease cases in the United States are acquired on the east coast between northern Virginia and New England. In recent years the geographic extent of Lyme disease has been expanding, raising the prospect of Lyme disease becoming endemic in the southeast. Methods.  We collected confirm...

journal_title：Open forum infectious diseases

authors： Lantos PM,Nigrovic LE,Auwaerter PG,Fowler VG Jr,Ruffin F,Brinkerhoff RJ,Reber J,Williams C,Broyhill J,Pan WK,Gaines DN

更新日期：2015-09-27 00:00:00

abstract：:The diabetic foot infection remains a major cause of morbidity and mortality in many patients and remains a challenging diagnosis for most clinicians. Diagnosis is largely based on clinical signs supplemented by various imaging tests. Magnetic resonance imaging (MRI) is not readily available to many clinicians, and bo...

journal_title：Open forum infectious diseases

authors： Markanday A

更新日期：2014-08-07 00:00:00

abstract：Background:We recently reported that the levels of activation, exhaustion, and terminal differentiation within the peripheral T-cell compartment were increased in men who have sex with men (MSM) compared with blood bank donors. During activation and differentiation, T cells undergo metabolic changes to maintain their e...

journal_title：Open forum infectious diseases

authors： Kruize Z,Maurer I,van Dort KA,van den Elshout MAM,Hoornenborg E,Booiman T,Prins M,Kootstra NA

更新日期：2020-07-05 00:00:00

abstract：BACKGROUND:Early diagnosis of human immunodeficiency virus (HIV) is a prerequisite to maximizing individual and societal benefits of antiretroviral therapy. METHODS:Adults ≥18 years of age testing HIV positive at 10 health facilities in Mozambique and Swaziland received point-of-care CD4+ cell count testing immediatel...

journal_title：Open forum infectious diseases

authors： Kujawski SA,Lamb MR,Lahuerta M,McNairy ML,Ahoua L,Abacassamo F,Nuwagaba-Biribonwoha H,Gachuhi A,El-Sadr WM,Elul B

更新日期：2017-07-23 00:00:00

abstract：Background:Identification of HIV infection at the early stage is valuable for patient management, for prevention, and for research purposes. In practice, identification of a recent HIV infection at diagnosis proves challenging after HIV antibody seroconversion but can be suspected using Western blots (WBs) or immunoblo...

journal_title：Open forum infectious diseases

authors： Stefic K,Mahjoub N,Desouche C,Néré ML,Thierry D,Delaugerre C,Barin F,Chaix ML

更新日期：2020-04-21 00:00:00

abstract：:This report describes a case of relapsing pneumococcal peritonitis. The postulated source of infection was vaginal colonization and secondary adherence of pneumococci to an intrauterine contraceptive device. After immunization with a conjugate pneumococcal vaccine, her antibody levels were observed. She remained infec...

journal_title：Open forum infectious diseases

authors： Sendi P,Moser Schaub EM,Nirgianakis K,Hathaway LJ,Bittel P,Goldblatt D,Streit S

更新日期：2016-12-07 00:00:00

abstract：Background:Klebsiella pneumoniae is a bacterial pathogen with increasing rates of resistance to carbapenem antibiotics, but the population structure and genetic drivers of carbapenem-resistant K pneumoniae (CRKP) remain underexplored in developing countries. Carbapenem-resistant K pneumoniae were recently introduced in...

journal_title：Open forum infectious diseases

authors： Roach D,Waalkes A,Abanto J,Zunt J,Cucho C,Soria J,Salipante SJ

更新日期：2020-07-02 00:00:00

abstract：Background:Post-kala-azar dermal leishmaniasis (PKDL) is a sequel to visceral leishmaniasis (VL), which is found in VL-endemic countries including Bangladesh. Because of these enigmatic cases, the success of the National Kala-azar Elimination Program is under threat. To date, diagnostic methods for PKDL cases in endemi...

journal_title：Open forum infectious diseases

authors： Ghosh P,Hasnain MG,Hossain F,Khan MAA,Chowdhury R,Faisal K,Mural MA,Baker J,Nath R,Ghosh D,Maruf S,Shomik MS,Haque R,Matlashewski G,Hamano S,Duthie MS,Mondal D

更新日期：2018-09-15 00:00:00

abstract：:Health-related quality of life (HRQoL) in outpatient parenteral antimicrobial therapy (OPAT) has not been well characterized in the United States. In an OPAT cohort, the short-form-12's median physical component score and mental component score were 40.3 and 54.4, respectively. HRQoL measures could be helpful in studi...

journal_title：Open forum infectious diseases

authors： Keller SC,Williams D,Levering M,Cosgrove SE

更新日期：2018-06-20 00:00:00

abstract：:People living with human immunodeficiency virus frequently use dietary supplements, including probiotics, but concern exists about ingesting live organisms. We performed a systematic review of the benefits of probiotics and a meta-analysis of sepsis risk. We undertook a protocol-driven, comprehensive review to identif...

journal_title：Open forum infectious diseases

authors： Carter GM,Esmaeili A,Shah H,Indyk D,Johnson M,Andreae M,Sacks HS

更新日期：2016-07-29 00:00:00

abstract：BACKGROUND:Postoperative infections are a common and often preventable complication of surgery. S. aureus is a prevalent organism cultured in these infections and is associated with morbidity, mortality, and increased healthcare utilization. However, the long-term burden of S. aureus infection in surgical patients is n...

journal_title：Open forum infectious diseases

authors： O'Brien WJ,Gupta K,Itani KMF

更新日期：2019-08-13 00:00:00