[Diffuse Intraparenchymal Mesothelioma: An Atypical Presentation].

Abstract:

:Pleural mesothelioma is a disease associated with exposure to asbestos. Although rare, it is the most common malignant pleural neoplasm. It is difficult to diagnose and it has a poor prognosis. We report the case of a 62-year-old male patient with a history of prolonged occupational exposure to asbestos, with dyspnea for minor exertion and productive cough, for several months. Imaging studies revealed extensive interstitial involvement with marked thickening of the interlobular and centrilobular septa and tenuous pleural involvement. Several differential diagnoses were considered such as, asbestosis, cryptogenic organizing pneumonia, desquamative interstitial pneumonia, pleuropulmonary metastases, and/or bronchopulmonary infection, but the histological and immunohistochemical results were compatible with pleural mesothelioma - a rare malignant neoplasm, with pleural origin, with a high mortality rate. :O mesotelioma pleural é uma doença associada à exposição ao amianto. Embora raro, é a principal neoplasia maligna da pleura, sendo o seu diagnóstico difícil e o seu prognóstico reservado. O caso clínico apresentado refere-se a um doente de 62 anos, do género masculino, com história ocupacional de exposição prolongada a amianto e clínica arrastada, com meses de evolução, de dispneia para pequenos esforços e tosse produtiva. Imagiologicamente, apresentava um envolvimento intersticial extenso com marcado espessamento dos septos interlobulares e centrilobulares, associado a ténues alterações pleurais. Várias hipóteses diagnósticas foram equacionadas tais como, asbestose, pneumonia organizativa criptogénica, pneumonia intersticial descamativa, metástases pleuropulmonares, e/ou patologia infeciosa broncopulmonar, mas o resultado histológico e imunohistoquímico foi compatível com mesotelioma pleural- uma neoplasia maligna rara, de origem pleural, com uma taxa de mortalidade elevada.

journal_name

Acta Med Port

journal_title

Acta medica portuguesa

authors

Pais A,Pinto N,Cardoso J,Fernandes M,Coutinho AI,Oliveira AS,Carvalho L,Bárbara C

doi

10.20344/amp.11406

subject

Has Abstract

pub_date

2020-02-03 00:00:00

pages

143-146

issue

2

eissn

0870-399X

issn

1646-0758

journal_volume

33

pub_type

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