Metformin Enhances Functional Recovery of Peripheral Nerve in Rats with Sciatic Nerve Crush Injury.

abstract：BACKGROUND:The prevalence of pressure ulcers (PUs) ranges from 1 to 18% of in-patients and from 3 to 28% in long-term settings. The aim of our study was to verify how comorbidity and frailty influenced the course of PUs in a population of elderly subjects hospitalized in a long-term care setting. MATERIAL/METHODS:The ...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Donini LM,De Felice MR,Tagliaccica A,De Bernardini L,Cannella C

更新日期：2005-07-01 00:00:00

abstract：:BACKGROUND MicroRNA-365 (miR-365) is involved in the development of a variety of cancers. However, it remains largely unknown if and how miRNAs-365 plays a role in melanoma development. MATERIAL AND METHODS In this study, we overexpressed miR-365 in melanoma cell lines A375 and A2058, via transfection of miR-365 mimic...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Zhu Y,Wen X,Zhao P

更新日期：2018-06-02 00:00:00

abstract：BACKGROUND:We evaluated changes in the levels of urinary 8-hydroxy-2-deoxyguanosine (8-OHdG) in patients undergoing mild hypothermia therapy and compared 8-OHdG expressions in those receiving whole-body cooling or selective head cooling. MATERIAL/METHODS:The subjects were 15 patients undergoing mild hypothermia therap...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Ikeda K,Ikeda T,Taniuchi H,Suda S

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:Attenuation of hyperinsulinemia by diazoxide (DZ), an inhibitor of glucose-mediated insulin secretion, in Zucker diabetic fatty (ZDF) rats, an animal model of type 2 diabetes and leptin resistance, decreased weight gain, improved lipid profile and prevented diabetes. Since the opposing effects of insulin and...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Alemzadeh R,Tushaus K

更新日期：2005-12-01 00:00:00

abstract：:BACKGROUND Neonatal acute respiratory distress syndrome (ARDS) is a common clinical syndrome caused by lung immaturity and the abnormal synthesis of pulmonary surfactant in preterm newborns, and it has high morbidity and mortality rates. The present study investigated the roles of interleukin-37 (IL-37) in the pathoge...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Li B,Ji X,Tian F,Gong J,Zhang J,Liu T

更新日期：2020-03-10 00:00:00

abstract：:BACKGROUND Emotional state can be affected by different training loads. The aim of this study was to explore the changes of rat emotional state, as well as the mRNA and protein expressions of N-methyl-D-aspartate receptors (NMDARs), postsynaptic density 95 (PSD-95), and kinesin family member 17 (KIF-17) in the hippoca...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Ren H,Yu X,Yu L,Zhang Y,Xie H,Shi N,Chen L

更新日期：2017-10-17 00:00:00

abstract：BACKGROUND:Bifenthrin is a synthetic pyrethroid insecticide derivative of naturally occurring pyrethrins from chrysanthemum flowers. Bifenthrin is considered relatively safe and therefore incorporated as the active ingredient in preparations sold over the counter for household use. Recent studies have raised concern th...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Nandi A,Chandil D,Lechesal R,Pryor SC,McLaughlin A,Bonventre JA,Flynnx K,Weeks BS

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND:The receptor-binding cancer antigen expressed on SiSo cells (RCAS1) is a human tumor-associated antigen that has been considered to play a crucial role in tumor progression by enabling cancer cells to evade immune surveillance. The present study aimed to evaluate the clinical significance of RCAS1 expression...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Theocharis S,Klijanienko J,Giaginis C,Rodriguez J,Jouffroy T,Girod A,Tsourouflis G,Sastre-Garau X

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:Despite the wide application of open reduction and internal fixation with locking plates for the treatment of proximal humeral fractures, the surgical invasive approach remains controversial. This study aimed to evaluate the pros and cons of the minimally invasive lateral approach for the treatment of proxim...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Liu K,Liu PC,Liu R,Wu X

更新日期：2015-02-15 00:00:00

abstract：BACKGROUND:Hormonal studies in patients with multiple sclerosis are rare and they often produce results which are difficult to interpret. These investigations, however, are becoming more and more important as they may cast some light on possible interrelationships between hormonal and immune systems. The aim of the pre...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Zych-Twardowska E,Wajgt A

更新日期：2001-09-01 00:00:00

abstract：:BACKGROUND Particulate matter 2.5 (PM2.5) in air pollution is regarded as a risk factor for cardiovascular disease (CVDs). Recently, it has become well accepted that polycyclic aromatic hydrocarbons (PAHs) in PM2.5 impacts human CVDs. However, few studies have shown miRNAs affected by PAHs play a critical role in tran...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： He X,Chen Y,Zhang C,Gong W,Zhang X,Nie S

更新日期：2018-08-25 00:00:00

abstract：BACKGROUND:The pro-inflammatory potential of lipoteichoic acid (LTA) from Staphylococcus aureus is controversial. The present study was undertaken to examine the ability of highly purified and characterized S. aureus LTA to stimulate the production of pro-inflammatory cytokines in human leukocytes at both mRNA and prot...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Ellingsen E,Morath S,Flo T,Schromm A,Hartung T,Thiemermann C,Espevik T,Golenbock D,Foster D,Solberg R,Aasen A,Wang J

更新日期：2002-05-01 00:00:00

abstract：BACKGROUND:The anti-oxidative and anti-inflammatory activities of electro-acupuncture (EA), a traditional clinical method, are widely accepted, but its mechanisms are not yet well defined. In this study, we investigated the role of extracellular signal-regulated kinases1/2 (ERK1/2) pathways on electro-acupuncture - med...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Zhang Y,Yu JB,Luo XQ,Gong LR,Wang M,Cao XS,Dong SA,Yan YM,Kwon Y,He J

更新日期：2014-08-16 00:00:00

abstract：:BACKGROUND Studies on monoamine oxidase B (MAO-B) expression in renal cell carcinoma (RCC) are lacking. This study focused on the immunohistochemical evaluation of MAO-B in RCC. MATERIAL AND METHODS Sixty-three RCC samples were compared on basic clinical and histopathological parameters, including histopathological ty...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Hodorová I,Rybárová S,Solár P,Benický M,Rybár D,Kováčová Z,Mihalik J

更新日期：2018-08-04 00:00:00

abstract：:BACKGROUND There are few triage methods based on patient age and extent of burn. However, in case of mass casualties, age might be hard to define. Burn segregation in mass-casualty accidents requires an easy, fast, and effective method. Triage in burns should also segregate casualties requiring treatment in burn cente...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Surowiecka-Pastewka A,Witkowski W,Kawecki M

更新日期：2018-03-31 00:00:00

abstract：:BACKGROUND This retrospective study at a single center aimed to evaluate the role of the red blood cell distribution width (RDW)-to-platelet ratio and other laboratory indices associated with the severity of histological hepatic fibrosis on liver biopsy in patients with autoimmune hepatitis (AIH). MATERIAL AND METHODS...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Li X,Xu H,Gao P

更新日期：2020-11-12 00:00:00

abstract：:BACKGROUND Septin9 is a member of GTP-binding protein family, and is used as a predictive diagnostic index. However, it has not been widely adopted due to inconsistent results reported in the literature. The present study was performed to determine the diagnostic accuracy of methylated Septin9 (mSEPT9) for colorectal ...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Yan S,Liu Z,Yu S,Bao Y

更新日期：2016-09-25 00:00:00

abstract：:BACKGROUND Diabetes is a risk factor for coronary atherosclerosis and coronary heart disease. Resveratrol (RESV) is a natural compound with anti-inflammatory effects. The objective of this study is to evaluate the cardio protective effects of RESV in a diabetic rat model with coronary heart disease. MATERIAL AND METHO...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Huo X,Zhang T,Meng Q,Li C,You B

更新日期：2019-01-18 00:00:00

abstract：BACKGROUND:Intra-articular adhesion is a common complication in post-surgical knees. The formation of post-surgical joint adhesion could lead to serious conditions. All-trans retinoic acid (ATRA) is a physiological metabolite of vitamin A that has a wide range of biological activities. The aim of the study was to verif...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Wang Y,Zhang C,Cheng H,Douglas P,Wang Z,Lu Y

更新日期：2015-06-01 00:00:00

abstract：INTRODUCTION:As numerous papers have presented many disturbances of blood lipid composition and changes in lipolytic enzyme activity, it was considered appropriate to investigate the postheparin lipolytic activity in serum of psoriatic males. The course of serum lipolytic process provoked by intravenous application of ...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Pietrzak A,Lecewicz-Toruń B,Borzecki A

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND:The aim of the study was to investigate whether children born small for gestational age without other complications nor signs of neurological impairment or developmental delay before 18 months of age may display neuropsychological impairments later in life. MATERIAL/METHODS:Neuropsychological outcome, schoo...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Viggedal G,Lundalv E,Carlsson G,Kjellmer I

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:CC chemokine receptors are likely to have important roles in the regulation of leukocytes and mast cells. Chemokine receptors are crucial in orchestrating innate and acquired immune responses as well as in allergic inflammation. A disturbance in erythrocyte function can lead to bronchial hyperreactivity and ...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Tyagi MG,Goyal S,Sathyakumar K,Subbana PK

更新日期：2006-08-01 00:00:00

abstract：BACKGROUND:The incidence of hepatocellular carcinoma (HCC) continues to increase in Japan, but the clinical characteristics of Japanese patients with HCC have not been well described. The aim of this study was to determine the frequencies and utilities of elevated a-fetoprotein (AFP) and des-gamma-carboxy prothrombin (...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Taura N,Ichikawa T,Miyaaki H,Ozawa E,Tsutsumi T,Tsuruta S,Kato Y,Goto T,Kinoshita N,Fukushima M,Kato H,Ohata K,Ohba K,Masuda J,Hamasaki K,Yatsuhashi H,Nakao K

更新日期：2013-09-06 00:00:00

abstract：:BACKGROUND The aim of our study was to investigate the risk factors for falls in the rheumatoid arthritis (RA) patient population in Poland. This would be a major step towards the development of new fall prevention programs. MATERIAL AND METHODS There were 450 RA patients who met the criteria of the American College o...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Mikos M,Kucharska E,Lulek AM,Kłosiński M,Batko B

更新日期：2020-04-15 00:00:00

abstract：BACKGROUND:The aim of this study was to investigate associations between the immune component of the oral cavity, lysozyme, in gingival crevicular fluid and unstimulated saliva, and colonization dynamics of periodontopathogenic bacteria from supra- and subgingival plaque samples in patients with gingivitis or periodont...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Surna A,Kubilius R,Sakalauskiene J,Vitkauskiene A,Jonaitis J,Saferis V,Gleiznys A

更新日期：2009-02-01 00:00:00

abstract：:BACKGROUND Endothelial progenitor cells (EPCs) were found to be a potential therapeutic choice for low extremity deep vein thrombosis. The aim of our research was to investigate the effect of resveratrol (RSV) on EPCs that may promote thrombus resolution and its potential pathway. MATERIAL AND METHODS EPCs were pretre...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Zhang Y,Du X,Li W,Sang H,Qian A,Sun L,Li X,Li C

更新日期：2018-02-15 00:00:00

abstract：:BACKGROUND The relationship between thyroid hormones and body anthropometric measures in type 2 diabetes mellitus (T2DM) patients with normal thyroid function is unclear. The purpose of this study was to evaluate the association between thyroid hormones and body composition in euthyroid T2DM patients in men and women....

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Chen L,Zhang M,Xiang S,Jiang X,Gu H,Sha Q,Qu M,Xu T

更新日期：2021-01-02 00:00:00

abstract：BACKGROUND:Ventricular tachycardia (VT) is frequently seen in ischemic settings like acute myocardial infarction with ST segment elevation (STEMI). Endothelial dysfunction (ED) represents inflammation and the loss of all protective features of the endothelium. We aimed to examine the association between VT and ED in pa...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Škerk V,Markotić A,Delić Brkljačić D,Manola S,Krčmar T,Gabrić ID,Stajminger G,Pintarić H

更新日期：2013-11-20 00:00:00

abstract：INTRODUCTION:The number of works on investigation of crush syndrome (CS) pathogenesis, of organs and enzymatic systems at traumatic toxicosis is rather limited. While the clinical current of trauma and the lethality prognosis depend on a degree of violations in them. Such investigations are necessary for opportune diag...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Hayrapetyan HL,Khachatryan HF,Mardanyan SS,Kevorkian GA

更新日期：2000-09-01 00:00:00

abstract：:Tolerance represents a dynamic mechanism that can be used to temper various regulatory processes regardless of whether they mediate excitation or inhibition. Tolerance operationally directs state-dependent attenuation of the action of endogenous and exogenous morphine. For example, tolerance ensures that immuno-inhibi...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Stefano GB,Kream RM,Esch T

更新日期：2009-09-01 00:00:00