The Melanin-Concentrating Hormone (MCH) System: A Tale of Two Peptides.

abstract：:Social conflict is a major source of stress in humans. Animals also experience social conflicts and cope with them by stress responses that facilitate arousal and activate sympathetic and neuroendocrine systems. The effect of acute social defeat (SoD) stress on the sleep/wake behavior of mice has been reported in seve...

journal_title：Frontiers in neuroscience

authors： Fujii S,Kaushik MK,Zhou X,Korkutata M,Lazarus M

更新日期：2019-04-03 00:00:00

abstract：:Brain-machine interfaces (BMIs) seek to connect brains with machines or computers directly, for application in areas such as prosthesis control. For this application, the accuracy of the decoding of movement intentions is crucial. We aim to improve accuracy by designing a better encoding model of primary motor cortica...

journal_title：Frontiers in neuroscience

authors： Li S,Li J,Li Z

更新日期：2016-12-22 00:00:00

abstract：:Background: Tinnitus is a very common symptom that often causes distress and decreases the patient's quality of life. Apart from the well-known causes, tinnitus can in some cases be elicited by dysfunctions of the cervical spine or the temporomandibular joint (TMJ). To date however, it is unclear whether alleviation o...

journal_title：Frontiers in neuroscience

authors： Michiels S,Naessens S,Van de Heyning P,Braem M,Visscher CM,Gilles A,De Hertogh W

更新日期：2016-11-29 00:00:00

abstract：:Duchenne muscular dystrophy (DMD) is a lethal X-linked muscular disease caused by defective expression of the cytoskeletal protein dystrophin (Dp427). Selected autonomic and central neurons, including retinal neurons, express Dp427 and/or dystrophin shorter isoforms. Because of this, DMD patients may also experience d...

journal_title：Frontiers in neuroscience

authors： Persiconi I,Cosmi F,Guadagno NA,Lupo G,De Stefano ME

更新日期：2020-08-31 00:00:00

abstract：:Extrapancreatic nerves project to pancreatic islets directly or converge onto intrapancreatic ganglia. Intrapancreatic ganglia constitute a complex information-processing center that contains various neurotransmitters and forms an endogenous neural network. Both intrapancreatic ganglia and extrapancreatic nerves have ...

journal_title：Frontiers in neuroscience

authors： Li W,Yu G,Liu Y,Sha L

更新日期：2019-02-20 00:00:00

abstract：:Evidence is mounting that LRRK2 function, particularly its kinase activity, is elevated in multiple forms of Parkinson's disease, both idiopathic as well as familial forms linked to mutations in the LRRK2 gene. However, sensitive quantitative markers of LRRK2 activation in clinical samples remain at the early stages o...

journal_title：Frontiers in neuroscience

authors： Rideout HJ,Chartier-Harlin MC,Fell MJ,Hirst WD,Huntwork-Rodriguez S,Leyns CEG,Mabrouk OS,Taymans JM

更新日期：2020-08-18 00:00:00

abstract：:Metabolic confusion has been linked to the pathogenesis of Parkinson's disease (PD), while the dynamic changes associated with the onset and progression of PD remain unclear. Herein, dynamic changes in metabolites were detected from the initiation to the development of 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPT...

journal_title：Frontiers in neuroscience

authors： Lu Y,Zhang X,Zhao L,Yang C,Pan L,Li C,Liu K,Bai G,Gao H,Yan Z

更新日期：2018-02-20 00:00:00

abstract：:Our team has been a pioneer in harvesting extracellular vesicles (EVs) enriched for neuronal origin from peripheral blood and using them as a biomarker discovery platform for neurological disorders. This methodology has demonstrated excellent diagnostic and predictive performance for Alzheimer's and other neurodegener...

journal_title：Frontiers in neuroscience

authors： Mustapic M,Eitan E,Werner JK Jr,Berkowitz ST,Lazaropoulos MP,Tran J,Goetzl EJ,Kapogiannis D

更新日期：2017-05-22 00:00:00

abstract：:It is known that various endocrine modulators, including leptin and ghrelin, have neuroprotective roles in neurological diseases. Leptin is a hormone produced by adipocytes and was originally identified as a gene related to obesity in mice. The leptin receptors in the hypothalamus are the main target for the homeostat...

journal_title：Frontiers in neuroscience

authors： Fujita Y,Yamashita T

更新日期：2019-08-07 00:00:00

abstract：:During the last decades, neuroscientists have increasingly exploited a variety of artificial, de-novo synthesized materials with controlled nano-sized features. For instance, a renewed interest in the development of prostheses or neural interfaces was driven by the availability of novel nanomaterials that enabled the ...

journal_title：Frontiers in neuroscience

authors： Pampaloni NP,Giugliano M,Scaini D,Ballerini L,Rauti R

更新日期：2019-01-15 00:00:00

abstract：:Throughout the past decade, silicon-based neural probes have become a driving force in neural engineering. Such probes comprise sophisticated, integrated CMOS electronics which provide a large number of recording sites along slender probe shanks. Using such neural probes in a chronic setting often requires them to be ...

journal_title：Frontiers in neuroscience

authors： Chauvière L,Pothof F,Gansel KS,Klon-Lipok J,Aarts AAA,Holzhammer T,Paul O,Singer WJ,Ruther P

更新日期：2019-05-21 00:00:00

abstract：:People are very precise in the discrimination of a line orientation relative to the cardinal (vertical and horizontal) axes, while their orientation discrimination sensitivity along the oblique axes is less refined. This difference in discrimination sensitivity along cardinal and oblique axes is called the "oblique ef...

journal_title：Frontiers in neuroscience

authors： Sysoeva OV,Davletshina MA,Orekhova EV,Galuta IA,Stroganova TA

更新日期：2016-01-21 00:00:00

abstract：:The Iowa Gambling Task (IGT) has been widely used to assess differences in decision-making under uncertainty. Recently, several studies have shown that healthy subjects do not meet the basic predictions of the task (i.e., prefer options with positive long-term outcome), hence questioning its basic assumptions. Since c...

journal_title：Frontiers in neuroscience

authors： Horstmann A,Villringer A,Neumann J

更新日期：2012-05-14 00:00:00

abstract：:Micro-Graphitic Single Crystal Diamond Multi Electrode Arrays (μG-SCD-MEAs) have so far been used as amperometric sensors to detect catecholamines from chromaffin cells and adrenal gland slices. Besides having time resolution and sensitivity that are comparable with carbon fiber electrodes, that represent the gold sta...

journal_title：Frontiers in neuroscience

authors： Tomagra G,Picollo F,Battiato A,Picconi B,De Marchis S,Pasquarelli A,Olivero P,Marcantoni A,Calabresi P,Carbone E,Carabelli V

更新日期：2019-04-09 00:00:00

abstract：:In functional MRI (fMRI), population receptive field (pRF) models allow a quantitative description of the response as a function of the features of the stimuli that are relevant for each voxel. The most popular pRF model used in fMRI assumes a Gaussian shape in the features space (e.g., the visual field) reducing the ...

journal_title：Frontiers in neuroscience

authors： Lage-Castellanos A,Valente G,Senden M,De Martino F

更新日期：2020-07-30 00:00:00

abstract：:Vagus nerve stimulation (VNS) therapy is associated with laryngeal muscle activation and induces voice modifications, well-known side effects of the therapy resulting from co-activation of the recurrent laryngeal nerve. In this study, we describe the non-invasive transcutaneous recording of laryngeal motor evoked pote...

journal_title：Frontiers in neuroscience

authors： Vespa S,Stumpp L,Bouckaert C,Delbeke J,Smets H,Cury J,Ferrao Santos S,Rooijakkers H,Nonclercq A,Raedt R,Vonck K,El Tahry R

更新日期：2019-08-27 00:00:00

abstract：:Schizophrenia is a complex disorder about which much is still unknown. Potential treatments, such as transcranial magnetic stimulation (TMS), have not been exploited, in part because of the variability in behavioral response. This can be overcome with the use of response biomarkers. It has been however shown that repe...

journal_title：Frontiers in neuroscience

authors： Aubonnet R,Banea OC,Sirica R,Wassermann EM,Yassine S,Jacob D,Magnúsdóttir BB,Haraldsson M,Stefansson SB,Jónasson VD,Ívarsson E,Jónasson AD,Hassan M,Gargiulo P

更新日期：2020-11-20 00:00:00

abstract：:Adapted exercise is an effective non-pharmacological tool to improve functional, cognitive, and psychological parameters in multiple sclerosis (MS), in association with increased quality of life (QoL) and decreased disease severity. Adipose tissue, through the production of different adipokines, is involved in regulat...

journal_title：Frontiers in neuroscience

authors： Grazioli E,Nigro E,Cerulli C,Borriello G,Mancini A,Tranchita E,Polito R,Parisi A,Buono P,Daniele A

更新日期：2020-12-22 00:00:00

abstract：:Despite evolutionary musicology's interdisciplinary nature, and the diverse methods it employs, the field has nevertheless tended to divide into two main positions. Some argue that music should be understood as a naturally selected adaptation, while others claim that music is a product of culture with little or no rel...

journal_title：Frontiers in neuroscience

authors： van der Schyff D,Schiavio A

更新日期：2017-09-29 00:00:00

abstract：:The sleep duration of adolescents has continued to decline over the past 20 years. Sleep insufficiency is one of the most important risk factors for obesity, but the mechanisms underlying the association are unclear. Therefore, the hypothalamic-regulated mechanisms of appetite and the circadian clock gene expression w...

journal_title：Frontiers in neuroscience

authors： Sun Q,Liu Y,Wei W,Wu D,Lin R,Wen D,Jia L

更新日期：2020-09-08 00:00:00

abstract：:Previous works exploring the challenges of ensuring information security for neuroprosthetic devices and their users have typically built on the traditional InfoSec concept of the "CIA Triad" of confidentiality, integrity, and availability. However, we argue that the CIA Triad provides an increasingly inadequate found...

journal_title：Frontiers in neuroscience

authors： Gladden ME

更新日期：2017-11-07 00:00:00

abstract：:Data from animal models and Alzheimer's disease (AD) subjects provide clear evidence for an activation of inflammatory pathways during the pathogenetic course of such illness. Biochemical and neuropathological studies highlighted an important cause/effect relationship between inflammation and AD progression, revealing...

journal_title：Frontiers in neuroscience

authors： Steardo L Jr,Bronzuoli MR,Iacomino A,Esposito G,Steardo L,Scuderi C

更新日期：2015-07-29 00:00:00

abstract：:Uncovering brain activity from magnetoencephalography (MEG) data requires solving an ill-posed inverse problem, greatly confounded by noise, interference, and correlated sources. Sparse reconstruction algorithms, such as Champagne, show great promise in that they provide focal brain activations robust to these confoun...

journal_title：Frontiers in neuroscience

authors： Owen JP,Sekihara K,Nagarajan SS

更新日期：2012-12-26 00:00:00

abstract：:Kolmer-Agduhr (KA) cells are a subgroup of interneurons positioned adjacent to the neurocoele with cilia on the apical surface protruding into the central canal of the spinal cord. Although KA cells were identified almost a century ago, their development and functions are only beginning to be unfolded. Recent studies ...

journal_title：Frontiers in neuroscience

authors： Yang L,Wang F,Strähle U

更新日期：2020-10-09 00:00:00

abstract：:Hearing loss can develop as a consequence of primary auditory neuron degeneration. These neurons are present within the spiral ganglion of the inner ear and co-exist with glial cells that assist in neuronal maintenance and function. There are limited interventions for individuals with hearing impairment, hence novel b...

journal_title：Frontiers in neuroscience

authors： Meas SJ,Nishimura K,Scheibinger M,Dabdoub A

更新日期：2018-11-13 00:00:00

abstract：:A patient with early achalasia presented spontaneous strong rhythmic non-propulsive contractions at ~7/min, independent of swallows. Our aim was to evaluate characteristics of the rhythmic contractions, provide data on the structure of pacemaker cells in the esophagus and discuss a potential role for interstitial cell...

journal_title：Frontiers in neuroscience

authors： Chen JH,Wang XY,Liu LW,Yu W,Yu Y,Zhao L,Huizinga JD

更新日期：2013-05-21 00:00:00

abstract：:Spasticity is a common comorbidity associated with spinal cord injury (SCI). Robotic exoskeletons have recently emerged to facilitate legged mobility in people with motor complete SCI. Involuntary muscle activity attributed to spasticity, however, can prevent such individuals from using an exoskeleton. Specifically, a...

journal_title：Frontiers in neuroscience

authors： Ekelem A,Goldfarb M

更新日期：2018-06-01 00:00:00

abstract：:In order to characterize the genetic architecture of epilepsy in a pediatric population from the Iberian Peninsula (including the Canary Islands), we conducted targeted exome sequencing of 246 patients with infantile-onset seizures with or without neurodevelopmental delay. We detected 107 variants in 48 different gene...

journal_title：Frontiers in neuroscience

authors： Fernández-Marmiesse A,Roca I,Díaz-Flores F,Cantarín V,Pérez-Poyato MS,Fontalba A,Laranjeira F,Quintans S,Moldovan O,Felgueroso B,Rodríguez-Pedreira M,Simón R,Camacho A,Quijada P,Ibanez-Mico S,Domingno MR,Benito C,Calvo

更新日期：2019-11-08 00:00:00

abstract：:Magnetic resonance imaging (MRI) studies have highlighted subcortical, cortical, and structural connectivity abnormalities associated with attention-deficit/hyperactivity disorder (ADHD). Gyrification investigations of the cortex have been inconsistent and largely negative, potentially due to a lack of sensitivity of ...

journal_title：Frontiers in neuroscience

authors： Forde NJ,Ronan L,Zwiers MP,Alexander-Bloch AF,Faraone SV,Oosterlaan J,Heslenfeld DJ,Hartman CA,Buitelaar JK,Hoekstra PJ

更新日期：2017-04-20 00:00:00

abstract：:Concerns regarding a drought in psychopharmacology have risen from many quarters. From one perspective, the wellspring of bedrock medications for anxiety disorders, depression, and schizophrenia was serendipitously discovered over 30 year ago, the swell of pharmaceutical investment in drug discovery has receded, and t...

journal_title：Frontiers in neuroscience

authors： Macdonald K,Feifel D

更新日期：2013-03-15 00:00:00