STLV-1 as a model for studying HTLV-1 infection.

Abstract:

:Few years after HTLV-1 identification and isolation in humans, STLV-1, its simian counterpart, was discovered. It then became clear that STLV-1 is present almost in all simian species. Subsequent molecular epidemiology studies demonstrated that, apart from HTLV-1 subtype A, all human subtypes have a simian homolog. As HTLV-1, STLV-1 is the etiological agent of ATL, while no case of TSP/HAM has been described. Given its similarities with HTLV-1, STLV-1 represents a unique tool used for performing clinical studies, vaccine studies as well as basic science.

journal_name

Retrovirology

journal_title

Retrovirology

authors

Jégado B,Kashanchi F,Dutartre H,Mahieux R

doi

10.1186/s12977-019-0503-0

subject

Has Abstract

pub_date

2019-12-16 00:00:00

pages

41

issue

1

issn

1742-4690

pii

10.1186/s12977-019-0503-0

journal_volume

16

pub_type

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