Abstract:
PURPOSE:To report the clinical, functional, and magnetic resonance imaging (MRI)-based outcomes of a novel autologous-made matrix consisting of hyaline cartilage chips combined with mixed plasma poor rich in platelets clot and plasma rich in growth factors (PRGF) for the treatment of knee full-thickness cartilage or osteochondral defects. METHODS:Between July 2015 and January 2018, all patients with full-thickness cartilage or osteochondral defects undergoing this novel cartilage restoration surgical technique were approached for eligibility. Indications for this procedure included traumatic or atraumatic full-thickness knee cartilage defects or osteochondritis dissecans. Patients were included if they had no concomitant use of stem cells, previous ipsilateral cartilage repair procedure, or follow-up was less than 10 months. The outcomes included data on current symptoms, physical exam, patient-reported, and functional outcomes (visual analogue scale (VAS) for pain, Lysholm score, Tegner activity scale, International Knee Documentation Committee (IKDC) subjective form, Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) score, Lequesne index, and short form-12 (SF-12)) and the magnetic resonance observation of cartilage repair tissue (MOCART) score. These outcomes were compared to preoperative values, except for the MOCART score. RESULTS:Fifteen patients were included in this preliminary study: mean (standard deviation (SD), range) follow-up 15.9 months (7.2, 10-32), age 26.8 years (12.1, 16-58), and body mass index 23.2 (2.1, 19.3-26.9). There were 14 men (93%) and 1 woman (7%). There was a statistically significant improvement between pre- and postoperative periods for VAS for pain (p = 0.003), Lysholm score (p = 0.002), IKDC subjective form (p = 0.003), WOMAC for pain (p = 0.005), WOMAC for stiffness (p = 0.01), WOMAC for function (p = 0.002), Lequesne Index (p = 0.002), and SF-12 physical component summary (p = 0.007). The postoperative mean (SD; range) MOCART score was 70 (12.4; 40-85). CONCLUSIONS:The use of this novel cartilage restoration surgical technique provides excellent clinical, functional, and MRI-based outcomes in young, active individuals with full-thickness cartilage or osteochondral defects. LEVEL OF EVIDENCE:Level IV-Therapeutic case series.
journal_name
J Orthop Surg (Hong Kong)journal_title
Journal of orthopaedic surgery (Hong Kong)authors
Cugat R,Alentorn-Geli E,Navarro J,Cuscó X,Steinbacher G,Seijas R,Álvarez-Díaz P,Barastegui D,Laiz P,Samitier G,García-Balletbó Mdoi
10.1177/2309499019887547subject
Has Abstractpub_date
2020-01-01 00:00:00pages
2309499019887547issue
1eissn
1022-5536issn
2309-4990journal_volume
28pub_type
杂志文章abstract:PURPOSE:To compare quality of life, knee function, and physical activity in 33 elderly women with or without early-stage knee osteoarthritis (OA). METHODS:33 Japanese elderly women (mean age, 66 years) with (n=18) or without (n=15) early-stage knee OA symptoms (knee pain and decreased range of motion [ROM]) were recru...
journal_title:Journal of orthopaedic surgery (Hong Kong)
pub_type: 杂志文章
doi:10.1177/230949901001800107
更新日期:2010-04-01 00:00:00
abstract:PURPOSE:To evaluate the condition of the tendons and neurovascular bundles after percutaneous release for trigger finger of the middle, ring, and little fingers. METHODS:30 women and 13 men aged 20 to 55 (mean, 40) years underwent percutaneous release of the A1 pulley using a 18-gauge needle for 43 trigger fingers of ...
journal_title:Journal of orthopaedic surgery (Hong Kong)
pub_type: 杂志文章
doi:10.1177/230949901502300227
更新日期:2015-08-01 00:00:00
abstract:AIM:To determine whether a mechanical, high-frequency vibration device (Tenease™) can improve pain and function for the treatment of tennis elbow (TE), compared with standard treatment. METHODS:Adults presenting to an elbow clinic with a clinical diagnosis of TE were randomized to standard treatment with physiotherapy...
journal_title:Journal of orthopaedic surgery (Hong Kong)
pub_type: 杂志文章,随机对照试验
doi:10.1177/2309499018792744
更新日期:2018-05-01 00:00:00
abstract:PURPOSE:Interleukin 6 (IL-6) and the acute phase C-reactive protein (CRP) blood concentrations after lumbar spine fusion may be affected by age. The purpose of this prospective observational study was to assess postoperative serum levels of pro-inflammatory IL-6 and CRP after instrumented lumbar spine fusion surgery. W...
journal_title:Journal of orthopaedic surgery (Hong Kong)
pub_type: 杂志文章
doi:10.1177/2309499019826406
更新日期:2019-01-01 00:00:00
abstract::An 11-year-old girl presented with a progressive swelling of the right elbow after a contusion. Radiography and magnetic resonance imaging showed a densely calcified lesion with no periosteal reaction or fracture. The underlying bone and muscles had normal signal intensity. A bone scan revealed increased uptake over t...
journal_title:Journal of orthopaedic surgery (Hong Kong)
pub_type: 杂志文章
doi:10.1177/230949901101900125
更新日期:2011-04-01 00:00:00
abstract::An 84-year-old man who was receiving oral anticoagulation therapy presented with complete lumbar plexus palsy caused by a massive psoas haematoma. Conservative treatment rather than drainage of the haematoma was undertaken, because of the risk of bleeding complications and mortality. At the one-year follow-up, the pat...
journal_title:Journal of orthopaedic surgery (Hong Kong)
pub_type: 杂志文章
doi:10.1177/230949901202000119
更新日期:2012-04-01 00:00:00
abstract:PURPOSES:To examine radiographically the component motion in a bipolar prosthesis and to determine whether the self-centering mechanism really works in vivo. METHODS:38 patients with 41 bipolar hip endoprostheses (30 for coxarthrosis and 11 for osteonecrosis of femoral head) were included in this study. Two radiograph...
journal_title:Journal of orthopaedic surgery (Hong Kong)
pub_type: 杂志文章
doi:10.1177/230949900501300108
更新日期:2005-04-01 00:00:00
abstract:BACKGROUND:Metaphyseal sleeves have been used as metaphyseal filling implants to address bone loss during revision total knee replacements (TKRs). This study aims to compare the 2-year clinical and radiological outcomes of constraint implant with bone defect and constraint implant without or minimal bone defect in revi...
journal_title:Journal of orthopaedic surgery (Hong Kong)
pub_type: 杂志文章
doi:10.1177/2309499020926313
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:Cementless femoral reconstruction is challenging in hip dysplasia due to deformity of the proximal femur causing insufficient stem fixation and/or inadequate neck anteversion. Strategies to address these problems include the use of a modular stem or a distal fixation stem, but both stems have some characteri...
journal_title:Journal of orthopaedic surgery (Hong Kong)
pub_type: 杂志文章
doi:10.1177/2309499020956742
更新日期:2020-09-01 00:00:00
abstract:PURPOSE:To evaluate the role of sympathetic skin response (SSR) and three-phase bone scintigraphy (TPBS) in the diagnosis of complex regional pain syndrome (CRPS). METHODS:60 patients with CRPS of the hand were recruited. TPBS was performed using a bolus injection of 20 mCi of Tc-99m methylene diphosphonate in an ante...
journal_title:Journal of orthopaedic surgery (Hong Kong)
pub_type: 杂志文章
doi:10.1177/230949900601400310
更新日期:2006-12-01 00:00:00
abstract::This study reports a case of acute calcific tendinitis of the flexor carpi ulnaris in a 64-year-old woman. She presented with symptoms of acute ulnar nerve compression mimicking a volar compartment syndrome. Owing to rapidly progressive symptoms, emergency surgical exploration was carried out. Intra-operatively a larg...
journal_title:Journal of orthopaedic surgery (Hong Kong)
pub_type: 杂志文章
doi:10.1177/230949901202000333
更新日期:2012-12-01 00:00:00
abstract:PURPOSE:This study aimed to present the change in humeral retroversion (HR) angle (HRA) that occurs in childhood and young adulthood and the potential developmental difference that is observed in wrestlers. METHODS:HRA of dominant and non-dominant shoulders (DSHRA and NDSHRA, respectively) were measured using ultrason...
journal_title:Journal of orthopaedic surgery (Hong Kong)
pub_type: 杂志文章
doi:10.1177/2309499020985149
更新日期:2021-01-01 00:00:00
abstract:PURPOSE:Osteochondral impaction grafting to manage isolated chondral defects in femoral condyles usually uses a metal punch to impact the grafts into predrilled cavities. Damage to the chondrocytes during impaction is a concern, however, and new methods are being sought to minimise the damage. We studied if impaction w...
journal_title:Journal of orthopaedic surgery (Hong Kong)
pub_type: 杂志文章
doi:10.1177/230949900201000211
更新日期:2002-12-01 00:00:00
abstract:PURPOSE:To examine whether the activity of peripheral sympathetic nerves in animals with spinal cord injury can be controlled using therapeutic electrical stimulation. METHODS:The spinal cords of 6 Wistar rats were severed at T12/T13 disk level and were given continuous therapeutic electrical stimulation. Microneurogr...
journal_title:Journal of orthopaedic surgery (Hong Kong)
pub_type: 杂志文章
doi:10.1177/230949900501300211
更新日期:2005-08-01 00:00:00
abstract:PURPOSE:Fingertip replantation is a challenging and technically demanding procedure. A variety of venous drainage techniques have been attempted for successful fingertip replantation. We present a new venous drainage technique, known as serial multifocal incision for fingertip replantation. METHODS:Between 2006 and 20...
journal_title:Journal of orthopaedic surgery (Hong Kong)
pub_type: 杂志文章
doi:10.1177/2309499019831480
更新日期:2019-01-01 00:00:00
abstract:PURPOSE:To review nutritional status and outcome of 90 patients who underwent total hip arthroplasty (THA) or hemiarthroplasty. METHODS:Records of 51 women and 39 men aged 26 to 96 (median, 71) years who underwent elective THA (n=48) for osteoarthritis, or trauma-related THA (n=10) or hemiarthroplasty (n=32) for subca...
journal_title:Journal of orthopaedic surgery (Hong Kong)
pub_type: 杂志文章
doi:10.1177/230949901202000313
更新日期:2012-12-01 00:00:00
abstract:PURPOSE:To evaluate the relationship between posterolateral reconstruction, abductor muscle strength, and femoral offset following total hip arthroplasty. METHODS:Of 28 patients (56 limbs) we assessed, 12 underwent posterolateral reconstruction (reconstruction group) and 16 did not (non-reconstruction group). Isometri...
journal_title:Journal of orthopaedic surgery (Hong Kong)
pub_type: 杂志文章
doi:10.1177/230949900401200205
更新日期:2004-12-01 00:00:00
abstract:PURPOSE:This study aims at sharing our experience as how to obtain and identify axial view image of the acetabular anterior column in patients. METHODS:Pelvic computed tomography data of six normal adults were used to reconstruct three-dimensional (3D) models. The transparency of each 3D model was downgraded at the vi...
journal_title:Journal of orthopaedic surgery (Hong Kong)
pub_type: 杂志文章
doi:10.1177/2309499016685012
更新日期:2017-01-01 00:00:00
abstract:PURPOSE:To review the long-term results of 14 cases of histopathologically confirmed schwannoma of the hand and wrist treated with intracapsular tumour removal. METHODS:All operations were performed under loupe magnification and microsurgical dissection, and the tumour was removed after capsular (including endoneurium...
journal_title:Journal of orthopaedic surgery (Hong Kong)
pub_type: 杂志文章,评审
doi:10.1177/230949900501300309
更新日期:2005-12-01 00:00:00
abstract:PURPOSE:To identify factors related to knee flexion after total knee arthroplasty in a Chinese population. METHODS:Records of 242 total knee arthroplasties were retrospectively reviewed. The parameters evaluated were age, gender, diagnosis, preoperative knee flexion and extension, preoperative flexion arc, tibiofemora...
journal_title:Journal of orthopaedic surgery (Hong Kong)
pub_type: 杂志文章
doi:10.1177/230949900701500204
更新日期:2007-08-01 00:00:00
abstract:PURPOSE:To evaluate radiological and clinical outcome of minimally invasive plate osteosynthesis (MIPO) for tibial plateau fractures. METHODS:35 men and 6 women aged 19 to 75 (mean, 40; standard deviation [SD], 14) years underwent MIPO for displaced tibial plateau fractures. According to the Schatzker system, the tibi...
journal_title:Journal of orthopaedic surgery (Hong Kong)
pub_type: 杂志文章
doi:10.1177/230949901202000109
更新日期:2012-04-01 00:00:00
abstract::Tears of the triangular fibrocartilage complex (TFCC) often lead to chronic wrist pain. The commonly used 2-needle outside-in and inside-out suturing techniques require an extra incision to tie the sutures subcutaneously. We use a practical and cost-effective arthroscopic technique for treatment of peripheral Palmer t...
journal_title:Journal of orthopaedic surgery (Hong Kong)
pub_type: 杂志文章
doi:10.1177/230949900901700224
更新日期:2009-08-01 00:00:00
abstract:PURPOSE:To examine the effectiveness of a multidisciplinary rehabilitation programme for patients with chronic low back pain in Hong Kong, and to identify factors associated with work resumption. METHODS:57 men and 8 women aged 20 to 56 (mean, 39) years who had a more than 3-month history of low back pain and were unr...
journal_title:Journal of orthopaedic surgery (Hong Kong)
pub_type: 杂志文章
doi:10.1177/230949901001800201
更新日期:2010-08-01 00:00:00
abstract:PURPOSE:To report our experience with the PRECICE nail for limb lengthening in 23 patients. METHODS:Records of 15 female and 8 male patients aged 14 to 38 (mean, 23.6) years who underwent lengthening of the tibia (n=6) or femur (n=21) using the PRECICE nail were reviewed. The reasons for lengthening included trauma (n...
journal_title:Journal of orthopaedic surgery (Hong Kong)
pub_type: 杂志文章
doi:10.1177/1602400321
更新日期:2016-12-01 00:00:00
abstract::We describe a modified surgical technique developed to enhance the classical irrigation and debridement procedure to improve the possibilities of retaining an infected total knee arthroplasty. This technique, debridement antibiotic pearls and retention of the implant (DAPRI), aims to remove the intra-articular biofilm...
journal_title:Journal of orthopaedic surgery (Hong Kong)
pub_type: 杂志文章
doi:10.1177/2309499019874413
更新日期:2019-09-01 00:00:00
abstract::Open reduction and internal fixation for unstable fractures of the lateral end of the clavicle (Neer type II) is not complication-free. Most clavicle fractures can be successfully treated by conservative methods. Neer type II fractures have a reportedly high rate of nonunion, therefore internal fixation is recommended...
journal_title:Journal of orthopaedic surgery (Hong Kong)
pub_type: 杂志文章
doi:10.1177/230949900601400320
更新日期:2006-12-01 00:00:00
abstract::Tibial plateau fractures are multiple fracture patterns associated with soft-tissue injuries. Among which, the combined existence of posterolateral tibial plateau depression fracture with anterior cruciate ligament (ACL) rupture has been reported rarely. Meanwhile, surgical method for the treatment of depression fract...
journal_title:Journal of orthopaedic surgery (Hong Kong)
pub_type: 杂志文章,评审
doi:10.1177/2309499019891208
更新日期:2020-01-01 00:00:00
abstract:PURPOSE:To compare the short-term ambulatory function of elderly patients after fixation of unstable intertrochanteric fractures with either the AO-ASIF proximal femoral nail anti-rotation (PFNA) device or the dynamic hip screw (DHS). METHODS:63 patients aged 60 years or older underwent fixation for unstable intertroc...
journal_title:Journal of orthopaedic surgery (Hong Kong)
pub_type: 杂志文章
doi:10.1177/230949901302100309
更新日期:2013-12-01 00:00:00
abstract:OBJECTIVE:This study evaluated the efficacy of surgery for femoral neck fractures in children after a 24-h delay and the factors affecting the risk of complications. METHODS:The study included 16 children who underwent surgery after the first 24 h for femoral neck fractures. According to Delbet's classification, there...
journal_title:Journal of orthopaedic surgery (Hong Kong)
pub_type: 杂志文章
doi:10.1177/2309499019889682
更新日期:2020-01-01 00:00:00
abstract:PURPOSE:To compare anatomic, radiographic, and computed tomographic (CT) measurements of the proximal femur in an Indian population. METHODS:26 left and 24 right dried cadaveric femurs were obtained. Each femur was divided into segments at 10 cross-sectional levels from proximal to distal. At each level, anteroposteri...
journal_title:Journal of orthopaedic surgery (Hong Kong)
pub_type: 杂志文章
doi:10.1177/230949901001800211
更新日期:2010-08-01 00:00:00