Abstract:
:Circular RNAs (circRNAs), as a type of tissue specific RNA with more stable structure than linear RNAs, was poorly understood on its correlation with gastric cancer (GC). In this review, we outline the synthesis and characteristics of circRNAs and generalize their categories and functions. Through comprehensive analysis of the reported results, we find that circRNAs not only participate in the regulation of gastric cancer (GC) cell biological behaviors, such as proliferation, invasion, migration and epithelial mesenchymal transition (EMT), but also are related to the clinicopathological features of GC such as tumor differentiation, TNM stage and metastasis, etc. According to the present screening and verification results, circRNAs are suggested to be used as biomarkers for the early diagnosis and prognosis prediction of GC, and those circRNAs involved in the genesis and development of GC have the potential as novel targets for the individualized treatment of GC.
journal_name
J Cancerjournal_title
Journal of Cancerauthors
Fang X,Wen J,Sun M,Yuan Y,Xu Qdoi
10.7150/jca.32927subject
Has Abstractpub_date
2019-10-15 00:00:00pages
6105-6113issue
24issn
1837-9664pii
jcav10p6105journal_volume
10pub_type
杂志文章,评审abstract::The growth of research in the field of exercise oncology has resulted in a large evidence base for the role of physical activity in preventing and managing cancer outcomes. Nonetheless, there remain many unanswered questions across the multidisciplinary field. This study aimed to determine the priority research questi...
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journal_title:Journal of Cancer
pub_type: 杂志文章
doi:10.7150/jca.28917
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journal_title:Journal of Cancer
pub_type: 杂志文章
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更新日期:2019-08-28 00:00:00
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journal_title:Journal of Cancer
pub_type: 杂志文章
doi:10.7150/jca.14714
更新日期:2016-05-07 00:00:00
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pub_type: 杂志文章,评审
doi:10.7150/jca.27633
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journal_title:Journal of Cancer
pub_type: 杂志文章
doi:10.7150/jca.17080
更新日期:2017-04-09 00:00:00
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pub_type: 杂志文章
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journal_title:Journal of Cancer
pub_type: 杂志文章
doi:10.7150/jca.19633
更新日期:2017-10-23 00:00:00
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journal_title:Journal of Cancer
pub_type: 杂志文章
doi:10.7150/jca.22234
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journal_title:Journal of Cancer
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journal_title:Journal of Cancer
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