Altered Functional Connectivity of Striatum Based on the Integrated Connectivity Model in First-Episode Schizophrenia.

abstract：:Impaired manual dexterity is commonly observed in schizophrenia. However, a quantitative description of key sensorimotor components contributing to impaired dexterity is lacking. Whether the key components of dexterity are differentially affected and how they relate to clinical characteristics also remains unclear. We...

journal_title：Frontiers in psychiatry

authors： Térémetz M,Carment L,Brénugat-Herne L,Croca M,Bleton JP,Krebs MO,Maier MA,Amado I,Lindberg PG

更新日期：2017-07-10 00:00:00

abstract：:In clinical settings, nitrous oxide gas is a safe anesthetic used during childbirth, in dentistry, and to relieve anxiety in emergencies. Colloquially known as "hippy crack"' or "laughing gas," it is increasingly taken recreationally for its euphoric and relaxing effects and hallucinogenic properties. Using a self-rep...

journal_title：Frontiers in psychiatry

authors： Ehirim EM,Naughton DP,Petróczi A

更新日期：2018-01-22 00:00:00

abstract：:Diminished orienting to social stimuli, and particularly to faces, is a core feature of autism spectrum disorders (ASDs). Impaired face processing has been linked to atypical attention processes that trigger a cascade of pathological development contributing to impaired social communication. The aim of the present stu...

journal_title：Frontiers in psychiatry

authors： Bochet A,Franchini M,Kojovic N,Glaser B,Schaer M

更新日期：2021-01-13 00:00:00

abstract：:Alcohol is one of the leading risk factors for global disease burden and overconsumption leads to a wide variety of negative consequences in everyday life. Digital interventions have shown small positive effects in contributing to reductions in problematic use. Specific research on smartphone apps is sparse and the fe...

journal_title：Frontiers in psychiatry

authors： Berman AH,Molander O,Tahir M,Törnblom P,Gajecki M,Sinadinovic K,Andersson C

更新日期：2020-05-27 00:00:00

abstract：:Social cognition refers to the mental operations underlying social interactions. Given the major role of social cognitive deficits in the disability associated with severe psychiatric disorders, they therefore constitute a crucial therapeutic target. However, no easily understandable and transnosographic self-assessme...

journal_title：Frontiers in psychiatry

authors： Graux J,Thillay A,Morlec V,Sarron PY,Roux S,Gaudelus B,Prost Z,Brénugat-Herné L,Amado I,Morel-Kohlmeyer S,Houy-Durand E,Franck N,Carteau-Martin I,Danset-Alexandre C,Peyroux E

更新日期：2019-11-21 00:00:00

abstract：Background:Patients with schizophrenia and individuals at ultra-high risk for psychosis (UHR) have been reported to exhibit impaired recognition of facial emotion expressions. This impairment has involved both inaccuracy and negative bias of facial emotion recognition. The present study aimed to investigate whether UHR...

journal_title：Frontiers in psychiatry

authors： Seo E,Park HY,Park K,Koo SJ,Lee SY,Min JE,Lee E,An SK

更新日期：2020-06-26 00:00:00

abstract：:Motivated behaviors are often initiated in response to perturbations of homeostasis. Indeed, animals and humans have fundamental drives to procure (appetitive behaviors) and eventually ingest (consummatory behaviors) substances based on deficits in body fluid (e.g., thirst) and energy balance (e.g., hunger). Consumpti...

journal_title：Frontiers in psychiatry

authors： Hsu TM,McCutcheon JE,Roitman MF

更新日期：2018-09-03 00:00:00

abstract：:Background: Bipolar disorder (BD) has been associated with distributed network disruption, but little is known on how different clinical subtypes, particularly those with an earlier and later onset of disease, are related to connectivity changes in white matter (WM) tracts. Methods: Diffusion tensor imaging (DTI) and ...

journal_title：Frontiers in psychiatry

authors： Alves GS,Knöchel C,Paulitsch MA,Reinke B,Carvalho AF,Feddern R,Prvulovic D,Sudo FK,Pantel J,Reif A,Oertel V

更新日期：2018-10-09 00:00:00

abstract：:Depression is one of the most prevalent and serious mental disorders with a worldwide significant health burden. Metabolic abnormalities and disorders in patients with depression have attracted great research attention. Thirty-six metabolic biomarkers of clinical plasma metabolomics were detected by platform technolog...

journal_title：Frontiers in psychiatry

authors： Gao Y,Xu T,Zhao YX,Ling-Hu T,Liu SB,Tian JS,Qin XM

更新日期：2020-07-15 00:00:00

abstract：:Suicide is the most severe consequence of depression which has become a leading cause of disability and a global disease burden. Recent evidence indicates a central role of small molecules in the pathogenesis of depression and associated suicidal behaviors. However, there lacks a systemic exploration of small molecule...

journal_title：Frontiers in psychiatry

authors： Liu S

更新日期：2020-04-16 00:00:00

abstract：:Japan recently ordered a string of death sentences for offenders with mental illness. Based on the verdicts, we describe cases where one or more psychiatrists conducted psychiatric evaluations for several months and testified in lay judge courts. We compared these cases with those in which the death penalty was avoide...

journal_title：Frontiers in psychiatry

authors： Kashiwagi H,Hirabayashi N

更新日期：2018-11-02 00:00:00

abstract：Background:Depressive patients show less altruistic behavior. While, older adults present higher tendencies for altruism than younger adults. Depression and age are two of the influencing factors of altruism, kynurenine (KYN), and its metabolites. However, the characteristics of altruism in late-life depression (LLD) a...

journal_title：Frontiers in psychiatry

authors： Wu Y,Mai N,Weng X,Liang J,Ning Y

更新日期：2020-04-30 00:00:00

abstract：:Background: Attenuated positive psychotic symptoms represent the defining features of the clinical high-risk for psychosis (CHR-P) criteria. The effectiveness of each available treatment for reducing attenuated positive psychotic symptoms remains undetermined. This network meta-analysis (NMA) investigates the consiste...

journal_title：Frontiers in psychiatry

authors： Davies C,Radua J,Cipriani A,Stahl D,Provenzani U,McGuire P,Fusar-Poli P

更新日期：2018-06-12 00:00:00

abstract：:The human gut microbiome is emerging as a key modulator of homeostasis, with far-reaching implications for various multifactorial diseases, including anorexia nervosa (AN). Despite significant morbidity and mortality, the underlying mechanisms of this eating disorder are poorly understood, but the classical view defin...

journal_title：Frontiers in psychiatry

authors： Ghenciulescu A,Park RJ,Burnet PWJ

更新日期：2021-01-12 00:00:00

abstract：:Fatigue is a common and disabling symptom in patients with Multiple Sclerosis (PwMS). Its pathogenesis, however, is still not fully understood. Potential psychological roots, in particular, have received little attention to date. The present study examined the association of childhood adversities, specific trait chara...

journal_title：Frontiers in psychiatry

authors： Pust GEA,Dettmers C,Randerath J,Rahn AC,Heesen C,Schmidt R,Gold SM

更新日期：2020-08-28 00:00:00

abstract：Introduction:Although research over the past decade has resulted in significantly increased knowledge about distal risk factors for non-suicidal self-injury (NSSI), little is known about short-term (proximal) factors that predict NSSI thoughts and behaviors. Drawing on contemporaneous theories of NSSI, as well as the c...

journal_title：Frontiers in psychiatry

authors： Kiekens G,Hasking P,Nock MK,Boyes M,Kirtley O,Bruffaerts R,Myin-Germeys I,Claes L

更新日期：2020-03-20 00:00:00

abstract：:Butyrylcholinesterase (BChE) efficiently hydrolyzes acetylcholine (ACh) at high concentrations when acetylcholinesterase (AChE) is substrate-inhibited. Recent studies have shown that BChE also has a function that is independent of ACh, but it has not been fully explored. Low BChE expression is accompanied with higher ...

journal_title：Frontiers in psychiatry

authors： Chen S,Lin Z,Tan KL,Chen R,Su W,Zhao H,Tan Q,Tan W

更新日期：2020-09-11 00:00:00

abstract：:Research has demonstrated the short- and long-term impacts of maternal mental health and well-being on children's emotional and behavioral outcomes. It is thus important to better understand the antecedents of maternal depression and stress. The aim of this study was to determine whether the contribution of perceived ...

journal_title：Frontiers in psychiatry

authors： deMontigny F,Gervais C,Pierce T,Lavigne G

更新日期：2020-11-02 00:00:00

abstract：:Nonsuicidal Self-Injury (NSSI) and suicidality are common reasons for emergency presentations in child and adolescent psychiatry. Therefore, we focused on reasons for emergency presentations as well as specific characteristics of those presenting with NSSI or suicidality to an emergeny psychiatric service. We analyzed...

journal_title：Frontiers in psychiatry

authors： Franzen M,Keller F,Brown RC,Plener PL

更新日期：2020-01-17 00:00:00

abstract：:Major depressive disorder (MDD) is a very common stress-related mental disorder that carries a huge burden for affected patients and the society. It is associated with a high mortality that derives from suicidality and the development of serious medical conditions such as heart diseases, diabetes, and stroke. Although...

journal_title：Frontiers in psychiatry

authors： Menke A

更新日期：2019-02-28 00:00:00

abstract：:Pharmacogenomics represents a potentially powerful enhancement to the current standard of care for psychiatric patients. However, a variety of biological and technical challenges must be addressed in order to provide adequate clinical decision support for personalized prescribing and dosing based on genomic data. This...

journal_title：Frontiers in psychiatry

authors： Jarvis JP,Peter AP,Shaman JA

更新日期：2019-06-20 00:00:00

abstract：:Conscious attempts to regulate alcohol and drug use are often undermined by automatic attention and arousal processes that are activated in the context of salient cues. Response to these cues involves body and brain signals that are linked via dynamic feedback loops, yet no studies have targeted the cardiovascular sys...

journal_title：Frontiers in psychiatry

authors： Bates ME,Lesnewich LM,Uhouse SG,Gohel S,Buckman JF

更新日期：2019-09-05 00:00:00

abstract：:Alcohol use disorder (AUD) is a devastating public health problem in which both genetic and environmental factors play a role. Growing evidence supports that epigenetic regulation is one major mechanism in neuroadaptation that contributes to development of AUD. Meanwhile, epigenetic patterns can be modified by various...

journal_title：Frontiers in psychiatry

authors： Chen J,Hutchison KE,Bryan AD,Filbey FM,Calhoun VD,Claus ED,Lin D,Sui J,Du Y,Liu J

更新日期：2018-11-15 00:00:00

abstract：Objectives:Deviations from typical word use have been previously reported in clinical depression, but language patterns of mild depression (MD), as distinct from normal sadness (NS) and euthymic state, are unknown. In this study, we aimed to apply the linguistic approach as an additional diagnostic key for understandin...

journal_title：Frontiers in psychiatry

authors： Smirnova D,Cumming P,Sloeva E,Kuvshinova N,Romanov D,Nosachev G

更新日期：2018-04-10 00:00:00

abstract：:Recent work on the mechanisms underlying auditory verbal hallucination (AVH) has been heavily informed by self-monitoring accounts that postulate defects in an internal monitoring mechanism as the basis of AVH. A more neglected alternative is an account focusing on defects in auditory processing, namely a spontaneous ...

journal_title：Frontiers in psychiatry

authors： Cho R,Wu W

更新日期：2013-11-27 00:00:00

abstract：:Eating disorders (EDs) are serious psychopathologies characterized by a persistent disturbance in eating or eating-related behavior. Studies have shown EDs' detrimental consequences not only for patients, but also for their families. Nevertheless, a specific group that has so far been neglected, in both the research a...

journal_title：Frontiers in psychiatry

authors： Maon I,Horesh D,Gvion Y

更新日期：2020-06-30 00:00:00

abstract：:The nature of the relationship between cannabis use (CU) and psychosis is complex and remains unclear. Researchers and clinicians remain divided regarding key issues such as whether or not cannabis is an independent cause of psychosis and schizophrenia. This paper reviews the field in detail, examining questions of ca...

journal_title：Frontiers in psychiatry

authors： Burns JK

更新日期：2013-10-14 00:00:00

abstract：:Autism spectrum disorder (ASD) is a behaviorally defined disorder that is now thought to affect approximately 1 in 69 children in the United States. In most cases, the etiology is unknown, but several studies point to the interaction of genetic predisposition with environmental factors. The immune system is thought to...

journal_title：Frontiers in psychiatry

authors： Harville T,Rhodes-Clark B,Bennuri SC,Delhey L,Slattery J,Tippett M,Wynne R,Rose S,Kahler S,Frye RE

更新日期：2019-09-11 00:00:00

abstract：Background:Previous studies suggested bipolar disorder caused an aberrant alteration in the insular, putamen, and left superior frontal gyrus, which are the main components of the hate circuit. However, the relationship between the hate circuit and the pathophysiologic substrate underlying different phases of bipolar d...

journal_title：Frontiers in psychiatry

authors： Fan Z,Yang J,Zeng C,Xi C,Wu G,Guo S,Xue Z,Liu Z,Tao H

更新日期：2020-10-27 00:00:00

abstract：:Cocaine addiction is a widespread psychiatric condition still waiting for approved efficacious medications. Previous studies suggested that simultaneous activation of nociceptin opioid (NOP) and mu opioid (MOP) receptors could be a successful strategy to treat cocaine addiction, but the paucity of molecules co-activat...

journal_title：Frontiers in psychiatry

authors： Shen Q,Deng Y,Ciccocioppo R,Cannella N

更新日期：2017-11-13 00:00:00