Mechanisms Underlying Type 2 Diabetes Remission After Metabolic Surgery.

abstract：:[This corrects the article DOI: 10.3389/fendo.2019.00025.]. ...

journal_title：Frontiers in endocrinology

authors： Bhusal A,Rahman MH,Lee IK,Suk K

更新日期：2019-04-09 00:00:00

abstract：:[This corrects the article on p. 219 in vol. 8, PMID: 28912754.]. ...

journal_title：Frontiers in endocrinology

authors： Zengin A,Fulford AJ,Sawo Y,Jarjou LM,Schoenmakers I,Goldberg G,Prentice A,Ward KA

更新日期：2018-04-16 00:00:00

abstract：:Aging represents one of the most complicated and highly integrated somatic processes. Healthy aging is suggested to rely upon the coherent regulation of hormonal and neuronal communication between the central nervous system and peripheral tissues. The hypothalamus is one of the main structures in the body responsible ...

journal_title：Frontiers in endocrinology

authors： Martin B,Chadwick W,Janssens J,Premont RT,Schmalzigaug R,Becker KG,Lehrmann E,Wood WH,Zhang Y,Siddiqui S,Park SS,Cong WN,Daimon CM,Maudsley S

更新日期：2016-01-18 00:00:00

abstract：:Polycystic ovary syndrome (PCOS) is the commonest endocrine abnormality in women of reproductive age typically presenting with chronic oligo- or anovulation, clinical, or biochemical hyperandrogenism and polycystic ovarian morphology (PCOM). Restoring mono-ovulation is the ultimate goal of ovulation induction and most...

journal_title：Frontiers in endocrinology

authors： Laven JSE

更新日期：2019-02-12 00:00:00

abstract：:Poor sleep and obesity are both extraordinarily common in the US adolescent population and often occur simultaneously. This review explores the links between obesity and sleep, outlining what is known about the relationships between sleep characteristics, obesity, and cardiometabolic risk factors in youth. Sleep durat...

journal_title：Frontiers in endocrinology

authors： Gohil A,Hannon TS

更新日期：2018-07-10 00:00:00

abstract：:The Twist proteins (Twist-1 and -2) are highly conserved developmental proteins with key roles for the transcriptional regulation in mesenchymal cell lineages. They belong to the super-family of bHLH proteins and exhibit bi-functional roles as both activators and repressors of gene transcription. The Twist proteins ar...

journal_title：Frontiers in endocrinology

authors： Dobrian AD

更新日期：2012-08-30 00:00:00

abstract：:Over the past decade, the increasing prevalence of obesity and its associated metabolic disorders constitutes one of the most concerning healthcare issues for countries worldwide. In an effort to curb the increased mortality and morbidity derived from the obesity epidemic, various therapeutic strategies have been deve...

journal_title：Frontiers in endocrinology

authors： Ong BX,Brunmeir R,Zhang Q,Peng X,Idris M,Liu C,Xu F

更新日期：2020-02-27 00:00:00

abstract：:We sought to determine the efficacy of 12 weeks high-intensity interval training (HIIT), compared to moderate-intensity continuous training (MICT) on glucose control, cardiometabolic risk and microvascular complication markers in men living with type 2 diabetes (T2D). Both modalities were combined with resistance trai...

journal_title：Frontiers in endocrinology

authors： Wormgoor SG,Dalleck LC,Zinn C,Borotkanics R,Harris NK

更新日期：2018-08-28 00:00:00

abstract：:Dopamine (DA) has a vital role in the central nervous system and also modulates lipid and glucose metabolism. The present study aimed to investigate the effect of dopamine on insulin secretion and the underlying mechanisms in rat pancreatic β-cells. Data from the radioimmunoassay indicated that dopamine inhibited insu...

journal_title：Frontiers in endocrinology

authors： Liu M,Ren L,Zhong X,Ding Y,Liu T,Liu Z,Yang X,Cui L,Yang L,Fan Y,Liu Y,Zhang Y

更新日期：2020-04-07 00:00:00

abstract：:McCune-Albright Syndrome (MAS; OMIM # 174800) is a rare, sporadic disease caused by a post-zygotic, activating mutation in the guanine-nucleotide binding protein α-subunit (GNAS1) gene. MAS is characterized by the clinical triad of polyostotic fibrous dysplasia of bone, café-au-lait skin pigmentation and peripheral pr...

journal_title：Frontiers in endocrinology

authors： Corica D,Aversa T,Pepe G,De Luca F,Wasniewska M

更新日期：2018-06-22 00:00:00

abstract：:Objective: Circulating free DNA (cfDNA) in general and circulating tumor DNA (ctDNA) in particular is becoming an increasingly used form of liquid biopsy biomarkers. In this study, we are investigating the ability to detect ctDNA from the plasma of pituitary adenoma (PA) patients. Design: Tumor tissue samples were obt...

journal_title：Frontiers in endocrinology

authors： Megnis K,Peculis R,Rovite V,Laksa P,Niedra H,Balcere I,Caune O,Breiksa A,Nazarovs J,Stukens J,Konrade I,Pirags V,Klovins J

更新日期：2019-09-18 00:00:00

abstract：:Background: The management of children and adolescents with chronic kidney disease (CKD) and growth failure candidate for recombinant human growth hormone therapy (rhGH) is based on an appraisal of the literature established on a 2006 consensus statement and 2019 Clinical practice recommendations. The performance of t...

journal_title：Frontiers in endocrinology

authors： Cappa M,Maghnie M,Carbone V,Chioma L,Errichiello C,Giavoli C,Giordano M,Guazzarotti L,Klain A,Montini G,Murer L,Parpagnoli M,Pecoraro C,Pesce S,Verrina E

更新日期：2020-09-02 00:00:00

abstract：:Background: Amiodarone-induced thyrotoxicosis (AIT) is associated with significant morbidity and mortality, particularly in patients with cardiac failure. The aim of the study was to evaluate the management of AIT at a tertiary hospital specialising in cardiac failure and transplantation. Methods: Retrospective audit ...

journal_title：Frontiers in endocrinology

authors： Isaacs M,Costin M,Bova R,Barrett HL,Heffernan D,Samaras K,Greenfield JR

更新日期：2018-08-22 00:00:00

abstract：:JAK2 is a member of the Janus kinase (JAKs) family of non-receptor protein tyrosine kinases, which includes JAK1-3 and TYK2. JAKs serve as the cytoplasmic signaling components of cytokine receptors and are activated through cytokine-mediated trans-phosphorylation, which leads to receptor phosphorylation and recruitmen...

journal_title：Frontiers in endocrinology

authors： Hubbard SR

更新日期：2018-01-05 00:00:00

abstract：:Growth hormone (GH) has been used as an adjunct in the field of female infertility treatment for more than 25 years, although, apart from treating women with GH deficiency its role has not yet been clarified. Contributing to this lack of clarity is that several underpowered studies have been performed on women undergo...

journal_title：Frontiers in endocrinology

authors： Hart RJ

更新日期：2019-07-24 00:00:00

abstract：Background:Levothyroxine sodium (LT4) is the therapy of choice for hypothyroidism. In the last decade, new LT4 formulations, such as liquid and softgel capsules, became available. Even if some evidence has been reached in the efficacy of liquid LT4 in patients with suboptimal TSH on tablet LT4, the usefulness of softge...

journal_title：Frontiers in endocrinology

authors： Trimboli P,Virili C,Centanni M,Giovanella L

更新日期：2018-03-21 00:00:00

abstract：:Follicle-stimulating hormone (FSH), a major regulator of spermatogenesis, has a crucial function in the development and function of the testis and it is extensively given as a fertility treatment to stimulate spermatogenesis. We analyzed the effects of different FSH preparations (α-follitropin, β-follitropin, and urof...

journal_title：Frontiers in endocrinology

authors： Arato I,Grande G,Barrachina F,Bellucci C,Lilli C,Jodar M,Aglietti MC,Mancini F,Vincenzoni F,Pontecorvi A,Calafiore R,Oliva R,Luca G,Mancuso F,Milardi D

更新日期：2020-06-18 00:00:00

abstract：:Objectives: To evaluate the impact of metformin (MTF) use on TSH levels, thyroid volume and volume of benign thyroid nodules (TNs). Additionally, to study if iodine status influences the outcomes. Methods: A total of 23 euthyroid patients (42 TNs) with benign thyroid nodules, diagnosed by fine needle aspiration biopsy...

journal_title：Frontiers in endocrinology

authors： Dos Santos PB,Gertrudes LN,Conceição FL,de Andrade BM,de Carvalho DP,Vaisman M,Teixeira PFDS

更新日期：2019-07-17 00:00:00

abstract：:The neurosteroids progesterone and allopregnanolone regulate numerous neuroprotective functions in neural tissues including inhibition of epileptic seizures and cell death. Many of progesterone's actions are mediated through the nuclear progesterone receptor (PR), while allopregnanolone is widely considered to be devo...

journal_title：Frontiers in endocrinology

authors： Thomas P,Pang Y

更新日期：2020-06-24 00:00:00

abstract：:Background: Myostatin (Mstn), a member of the TGF-β superfamily, is a negative regulator of skeletal muscle mass in mammals. Precise regulation of Mstn expression is important for somite growth in fish. MicroRNA (miRNA), a type of small non-coding RNA, regulates gene expression at the post-transcriptional level and pa...

journal_title：Frontiers in endocrinology

authors： Zhao Z,Yu X,Jia J,Yang G,Sun C,Li W

更新日期：2019-12-03 00:00:00

abstract：:Despite the long-held belief that growth hormone supplementation provides psychosocial benefits to patients with Turner syndrome (TS), this assumption has never been rigorously tested in a randomized control trial. As a sub-study of the Canadian growth-hormone trial, parent-, and patient-completed standardized questio...

journal_title：Frontiers in endocrinology

authors： Rovet JF,Van Vliet G

更新日期：2019-03-13 00:00:00

abstract：:Reproductive status is tightly coupled to metabolic state in females, and ovarian cycling in mammals is halted when energy output exceeds energy input, a metabolic condition known as negative energy balance. This inhibition of reproductive function during negative energy balance occurs due to suppression of gonadotrop...

journal_title：Frontiers in endocrinology

authors： True C,Grove KL,Smith MS

更新日期：2011-10-17 00:00:00

abstract：:To investigate the expression of endothelial nitric oxide synthase (eNOS) and nitric oxide (NO) in the aorta of subclinical hypothyroidism (SCH) rat model. The mechanisms underlying thyrotropin (TSH) affecting eNOS and PGRN expression in human umbilical vein endothelial cells (HUVECs) cultured in vitro were investigat...

journal_title：Frontiers in endocrinology

authors： Jiang F,Wang H,Bao S,Zhou H,Zhang Y,Yan Y,Lai Y,Teng W,Shan Z

更新日期：2018-07-05 00:00:00

abstract：:Osteogenesis imperfecta (OI) is an inherited connective tissue disorder characterized by bone fragility and is characterized by clinical and genetic heterogeneity. Previous studies showed that the same mutation (c.-14C> T) of the IFITM5 gene is responsible for autosomal dominant OI type V. However, the mutation has a ...

journal_title：Frontiers in endocrinology

authors： Cao YJ,Wei Z,Zhang H,Zhang ZL

更新日期：2019-06-12 00:00:00

abstract：:The arcuate nucleus of the hypothalamus contains at least two populations of neurons that continuously monitor signals reflecting energy status and promote the appropriate behavioral and metabolic responses to changes in energy demand. Activation of neurons making pro-opiomelanocortin (POMC) decreases food intake and ...

journal_title：Frontiers in endocrinology

authors： Cansell C,Denis RG,Joly-Amado A,Castel J,Luquet S

更新日期：2012-12-27 00:00:00

abstract：:Background: The health benefits of soy are widely reported but there are queries on the effect of soy isoflavones on thyroid function and the underlying mechanism of action. Materials and Methods: We examined the effect of soy isoflavones on reverse tri-iodothyronine (or 3,3',5'-tri-iodothyronine; rT3) in two studies ...

journal_title：Frontiers in endocrinology

authors： Sathyapalan T,Köhrle J,Rijntjes E,Rigby AS,Dargham SR,Kilpatrick ES,Atkin SL

更新日期：2018-11-22 00:00:00

abstract：:Fibroblast growth factor 1 (FGF1) is reported to be expressed in the testis. How FGF1 affects stem Leydig cell development remains unclear. Here, we report the effects of FGF1 on rat stem Leydig cell development in an ethane dimethane sulfonate (EDS)-treated model. FGF1 (100 ng/testis) significantly increased serum te...

journal_title：Frontiers in endocrinology

authors： Chen L,Li X,Wang Y,Song T,Li H,Xie L,Li L,Chen X,Ma L,Chen Y,Lv Y,Li X,Ge RS

更新日期：2019-03-08 00:00:00

abstract：:Testosterone is responsible for several changes in the brain, including behavioral and emotional responses, memory, and cognition. Given this, we investigated changes in the brain wave profile caused by supplementation with exogenous testosterone in both castrated and non-castrated rats. We also investigated the serum...

journal_title：Frontiers in endocrinology

authors： Estumano DP,Ferreira LO,Bezerra PAL,da Silva MCP,Jardim GC,Santos GFS,Gustavo KS,Mattos BG,Ramos JAB,Jóia de Mello V,da Costa ET,Lopes DCF,Hamoy M

更新日期：2019-09-24 00:00:00

abstract：:Successful discontinuation of cabergoline (CAB) treatment has been reported in 31-75% of prolactinomas patients treated for at least 2 years. In contrast, it is not well established whether CAB therapy can be successfully withdrawn after a failed first attempt. This prospective open trial was designed to address this ...

journal_title：Frontiers in endocrinology

authors： Vilar L,Albuquerque JL,Gadelha PS,Rangel Filho F,Siqueira AM,da Fonseca MM,Viana KF,Gomes BS,Lyra R

更新日期：2015-02-04 00:00:00

abstract：:Radiotherapy continues to be one of the most accepted medical treatments for cancer. Localized irradiation is the most common treatment for prostate, pancreatic, rectal, cervical and endometrial malignancies. Conventional localized fractions are total doses of 30-62Gy at 1.8-2Gy per fraction, with administration of ~6...

journal_title：Frontiers in endocrinology

authors： Costa S,Reagan MR

更新日期：2019-08-29 00:00:00