Increased Nucleus Accumbens Connectivity in Resting-State Patients With Drug-Naive, First-Episode Somatization Disorder.

abstract：BACKGROUND:Evidence indicates that early life stress (ELS) can induce persistent changes in the hypothalamic-pituitary-adrenal (HPA) axis to respond to stress in the adult life that leads to depression. These appear to be related to the impairment of HPA hormones through binding to glucocorticoid (GR) and mineralocorti...

journal_title：Frontiers in psychiatry

authors： Baes Cv,Martins CM,Tofoli SM,Juruena MF

更新日期：2014-01-24 00:00:00

abstract：:Elevation of the blood ethanol concentration (BEC) to > 80 mg/dL (17.4 mM) after binge drinking enhances inflammation in brain and neuroimmune signaling pathways. Morphine abuse is frequently linked to excessive drinking. Morphine exerts its actions mainly via the seven transmembrane G-protein-coupled mu opioid recept...

journal_title：Frontiers in psychiatry

authors： Chang SL,Huang W,Han H,Sariyer IK

更新日期：2019-01-22 00:00:00

abstract：:Introduction: Previous studies on internet gaming disorder (IGD) have reported an association between personality traits and impulsive or problematic use of the internet or internet games, but the results obtained were inconsistent. Our study's hypothesis was that personality traits are associated with the individual'...

journal_title：Frontiers in psychiatry

authors： Seong W,Hong JS,Kim S,Kim SM,Han DH

更新日期：2019-08-28 00:00:00

abstract：:Cogmed Working Memory Training (CWMT), an online cognitive training program developed for children, is an increasingly popular non-pharmacological intervention for ADHD amongst all ages, despite limited supporting evidence. The initial objective of the present work was to examine the short- and long-term impacts of CW...

journal_title：Frontiers in psychiatry

authors： Marcelle ET,Ho EJ,Kaplan MS,Adler LA,Castellanos FX,Milham MP

更新日期：2018-08-28 00:00:00

abstract：:Background: Children of parents with a mental illness (COPMI) are more likely to experience negative long-term adversities. However, interventions to support their needs early can significantly enhance adjustment and reduce negative outcomes. Approximately one in four children currently lives with a parent with mental...

journal_title：Frontiers in psychiatry

authors： Christiansen H,Bauer A,Fatima B,Goodyear M,Lund IO,Zechmeister-Koss I,Paul JL

更新日期：2019-04-17 00:00:00

abstract：:Over half of those diagnosed with post-traumatic stress disorder (PTSD) have comorbid major depressive disorder (MDD), and rates are even higher among military veterans. Transcranial magnetic stimulation (TMS) may be a safe and efficacious treatment for PTSD, both with and without comorbid MDD. Still, the mechanism of...

journal_title：Frontiers in psychiatry

authors： Petrosino NJ,Zandvakili A,Carpenter LL,Philip NS

更新日期：2018-11-20 00:00:00

abstract：Background:Depressive patients show less altruistic behavior. While, older adults present higher tendencies for altruism than younger adults. Depression and age are two of the influencing factors of altruism, kynurenine (KYN), and its metabolites. However, the characteristics of altruism in late-life depression (LLD) a...

journal_title：Frontiers in psychiatry

authors： Wu Y,Mai N,Weng X,Liang J,Ning Y

更新日期：2020-04-30 00:00:00

abstract：Objective:Insomnia is associated with suicidality, although the mechanisms of this association are unclear. This study sought to replicate previous findings showing that insomnia symptoms but not sleep duration are associated with frequency of suicidal ideation in adults. We further investigated whether depression or s...

journal_title：Frontiers in psychiatry

authors： Simmons Z,Erickson LD,Hedges D,Kay DB

更新日期：2020-09-18 00:00:00

abstract：:The significant biochemical and physiological effects of psychological stress are beginning to be recognized as exacerbating common diseases, including osteoporosis. This review discusses the current evidence for psychological stress-associated mental health disorders as risk factors for osteoporosis, the mechanisms t...

journal_title：Frontiers in psychiatry

authors： Kelly RR,McDonald LT,Jensen NR,Sidles SJ,LaRue AC

更新日期：2019-04-09 00:00:00

abstract：Background:Nonsuicidal self-injury (NSSI) is highly prevalent in clinical and non-clinical populations of adolescents. Several studies have supported both the distinction and the strong association between NSSI and suicidal behavior. Although there is a great deal of data on the role of life events in both suicidal beh...

journal_title：Frontiers in psychiatry

authors： Horváth LO,Győri D,Komáromy D,Mészáros G,Szentiványi D,Balázs J

更新日期：2020-05-06 00:00:00

abstract：:Cognitive impairment is an important aspect of schizophrenia, where cognitive remediation therapy (CRT) is a promising treatment for improving cognitive functioning. While neurobiological dysfunction in schizophrenia has been the target of much research, the neural substrate of cognitive remediation and recovery has n...

journal_title：Frontiers in psychiatry

authors： Thorsen AL,Johansson K,Løberg EM

更新日期：2014-08-15 00:00:00

abstract：:Background: The personality trait neuroticism has been implicated in a poor response to stress, may relate to increased concentrations of cytokines and the development of depression. Inflammatory mechanisms may also be associated with the onset, severity and symptoms of depression. Both are related to poor antidepress...

journal_title：Frontiers in psychiatry

authors： Schmidt FM,Sander C,Minkwitz J,Mergl R,Dalton B,Holdt LM,Teupser D,Hegerl U,Himmerich H

更新日期：2018-11-20 00:00:00

abstract：:The prevalence of alcohol abuse among patients treated in accident and emergency departments (A&E) is considered as substantial. This paper is a narrative review of studies investigating the effectiveness of brief interventions (BI) for hazardous and harmful alcohol consumption in A&E. A&E departments in hospitals (an...

journal_title：Frontiers in psychiatry

authors： Wojnar M,Jakubczyk A

更新日期：2014-11-03 00:00:00

abstract：:We use auditory verbal hallucinations (AVH) to illustrate the challenges in defining and assessing target engagement in the context of transcranial direct current stimulation (tDCS) for psychiatric disorders. We defined the target network as the cluster of regions of interest (ROIs) that are consistently implicated in...

journal_title：Frontiers in psychiatry

authors： Lee WH,Kennedy NI,Bikson M,Frangou S

更新日期：2018-02-22 00:00:00

abstract：BACKGROUND:Schizophreniform syndromes can be divided into primary forms from polygenic causes or secondary forms due to immunological, epileptiform, monogenic, or degenerative causes. Steroid-responsive encephalopathy associated with autoimmune thyroiditis (SREAT) is a secondary immunological form associated with incre...

journal_title：Frontiers in psychiatry

authors： Endres D,Perlov E,Riering AN,Maier V,Stich O,Dersch R,Venhoff N,Erny D,Mader I,Tebartz van Elst L

更新日期：2017-04-21 00:00:00

abstract：:There is minimal knowledge about the impact of large-scale epidemics on community mental health, particularly during the acute phase. This gap in knowledge means we are critically ill-equipped to support communities as they face the unprecedented COVID-19 pandemic. This study aimed to provide data urgently needed to i...

journal_title：Frontiers in psychiatry

authors： Dawel A,Shou Y,Smithson M,Cherbuin N,Banfield M,Calear AL,Farrer LM,Gray D,Gulliver A,Housen T,McCallum SM,Morse AR,Murray K,Newman E,Rodney Harris RM,Batterham PJ

更新日期：2020-10-06 00:00:00

abstract：:Pharmacological approaches to cognitive enhancement have received considerable attention but have not had considerable success in improving their cognitive and functional targets. Other intervention strategies, such as cognitive remediation therapy (CRT), have been shown to enhance cognitive performance but have not b...

journal_title：Frontiers in psychiatry

authors： Harvey PD,Sand M

更新日期：2017-09-25 00:00:00

abstract：BACKGROUND:Attention deficit hyperactivity disorder (ADHD) is a prevalent neurodevelopmental disorder affecting children, adolescents, and adults. Its etiology is not well understood, but it is increasingly believed to result from diverse pathophysiologies that affect the structure and function of specific brain circui...

journal_title：Frontiers in psychiatry

authors： Khadka S,Pearlson GD,Calhoun VD,Liu J,Gelernter J,Bessette KL,Stevens MC

更新日期：2016-07-25 00:00:00

abstract：Background:Chronic insomnia is common in patients with arteriosclerotic cerebral small vessel disease (CSVD) and aggravates the cognitive impairment caused by CSVD. Low-dose trazodone is effective in treating insomnia, but it is unclear whether it can also improve cognitive function in CSVD patients. This study was per...

journal_title：Frontiers in psychiatry

authors： Wang J,Liu S,Zhao C,Han H,Chen X,Tao J,Lu Z

更新日期：2020-06-30 00:00:00

abstract：:Our recent microarray study reported altered mRNA expression of several low density lipoprotein receptor-related proteins (LRP) associated with the first 4 years following diagnosis with schizophrenia. Whilst this finding is novel, apolipoprotein E (APOE), which mediates its activity through LRPs, has been reported by...

journal_title：Frontiers in psychiatry

authors： Gibbons AS,Thomas EA,Scarr E,Dean B

更新日期：2010-07-08 00:00:00

abstract：:Background: The issue of treatment resistance in eating disorder care is controversial. Prior research has identified multiple failed treatment attempts as a common criterion for severe and enduring anorexia nervosa, but little is known about patients who have multiple failed treatment attempts. This study was designe...

journal_title：Frontiers in psychiatry

authors： Smith S,Woodside DB

更新日期：2021-01-08 00:00:00

abstract：:Investigation in posttraumatic stress disorder (PTSD) shows a negative association between patients' degrees of acceptance (the willingness to face unwanted private experiences while pursuing one's values and goals) and those of clinical symptom severity, suggesting that experiential acceptance is a protective factor ...

journal_title：Frontiers in psychiatry

authors： Jung WH,Kim NH

更新日期：2020-07-30 00:00:00

abstract：:The use of smartphone apps for research and clinical care in mental health has become increasingly popular, especially within youth mental health. In particular, digital phenotyping, the monitoring of data streams from a smartphone to identify proxies for functional outcomes like steps, sleep, and sociability, is of i...

journal_title：Frontiers in psychiatry

authors： Wisniewski H,Henson P,Torous J

更新日期：2019-09-23 00:00:00

abstract：:The graph theoretical analysis of structural magnetic resonance imaging (MRI) data has received a great deal of interest in recent years to characterize the organizational principles of brain networks and their alterations in psychiatric disorders, such as schizophrenia. However, the characterization of networks in cl...

journal_title：Frontiers in psychiatry

authors： Edwin Thanarajah S,Han CE,Rotarska-Jagiela A,Singer W,Deichmann R,Maurer K,Kaiser M,Uhlhaas PJ

更新日期：2016-06-30 00:00:00

abstract：:While psychological treatments have been shown to be effective in treating psychiatric disorders, the mechanism of their therapeutic effect is less well understood. An improved mechanistic understanding of psychiatric disorders and their treatments would enable refinement of existing interventions, and more targeted i...

journal_title：Frontiers in psychiatry

authors： Griffin B,Saunders KEA

更新日期：2020-01-17 00:00:00

abstract：:This paper presents the first systematic case-control study of correlates of mass psychogenic illness (MPI) in an adolescent school population. MPI is generally construed as a dissociative phenomenon spread by social contagion to individuals who are prone to dissociation. We sought to test if the correlates of dissoci...

journal_title：Frontiers in psychiatry

authors： Sapkota RP,Brunet A,Kirmayer LJ

更新日期：2020-11-17 00:00:00

abstract：:Introduction: Post-Traumatic Stress Disorder (PTSD) is a prevalent, severe and tenacious psychopathological consequence of traumatic events. Neurobehavioral mechanisms underlying PTSD pathogenesis have been identified, and may serve as risk-resilience factors during the early aftermath of trauma exposure. Longitudinal...

journal_title：Frontiers in psychiatry

authors： Ben-Zion Z,Fine NB,Keynan NJ,Admon R,Green N,Halevi M,Fonzo GA,Achituv M,Merin O,Sharon H,Halpern P,Liberzon I,Etkin A,Hendler T,Shalev AY

更新日期：2018-10-04 00:00:00

abstract：:In depression, brain and behavioral correlates of decision-making differ between individuals with and without suicidal thoughts and behaviors. Though promising, it remains unknown if these potential biomarkers of suicidality will generalize to other high-risk clinical populations. To preliminarily assess whether brain...

journal_title：Frontiers in psychiatry

authors： Barredo J,Aiken E,van 't Wout-Frank M,Greenberg BD,Carpenter LL,Philip NS

更新日期：2019-02-12 00:00:00

abstract：:Renewing interest in immune aspects of schizophrenia and new findings about the brain-fat axis encourage us to discuss the possible role of interleukin-6 (IL-6) in schizophrenia. Previously, it was suggested that a primary alteration of the innate immune system may be relevant in schizophrenia. Functional dichotomy of...

journal_title：Frontiers in psychiatry

authors： Borovcanin MM,Jovanovic I,Radosavljevic G,Pantic J,Minic Janicijevic S,Arsenijevic N,Lukic ML

更新日期：2017-11-06 00:00:00

abstract：:The human gut microbiome is emerging as a key modulator of homeostasis, with far-reaching implications for various multifactorial diseases, including anorexia nervosa (AN). Despite significant morbidity and mortality, the underlying mechanisms of this eating disorder are poorly understood, but the classical view defin...

journal_title：Frontiers in psychiatry

authors： Ghenciulescu A,Park RJ,Burnet PWJ

更新日期：2021-01-12 00:00:00