Insights on the Role of Putative Muscle-Derived Factors on Pancreatic Beta Cell Function.

abstract：:Octopuses (Octopus vulgaris) are generally considered to possess extraordinary cognitive abilities including the ability to successfully perform in a serial reversal learning task. During reversal learning, an animal is presented with a discrimination problem and after reaching a learning criterion, the signs of the s...

journal_title：Frontiers in physiology

authors： Bublitz A,Weinhold SR,Strobel S,Dehnhardt G,Hanke FD

更新日期：2017-02-07 00:00:00

abstract：:Duchenne muscular dystrophy (DMD) is characterized by rapid wasting of skeletal muscle. Mitochondrial dysfunction is a well-known pathological feature of DMD. However, whether mitochondrial dysfunction occurs before muscle fiber damage in DMD pathology is not well known. Furthermore, the impact upon heterozygous femal...

journal_title：Frontiers in physiology

authors： Moore TM,Lin AJ,Strumwasser AR,Cory K,Whitney K,Ho T,Ho T,Lee JL,Rucker DH,Nguyen CQ,Yackly A,Mahata SK,Wanagat J,Stiles L,Turcotte LP,Crosbie RH,Zhou Z

更新日期：2020-06-19 00:00:00

abstract：:Increasing water CO2, aquatic hypercapnia, leads to higher physiological pCO2 levels in fish, resulting in an acidosis and compensatory acid-base regulatory response. Senegalese sole is currently farmed in super-intensive recirculating water systems where significant accumulation of CO2 in the water may occur. Moreove...

journal_title：Frontiers in physiology

authors： Machado M,Arenas F,Svendsen JC,Azeredo R,Pfeifer LJ,Wilson JM,Costas B

更新日期：2020-01-31 00:00:00

abstract：Background:Sickle cell disease (SCD) patients with asthma have an increased rate of vaso-occlusive crisis (VOC) and acute chest syndrome (ACS) episodes when compared to those without asthma. We hypothesized that either asthma diagnosis or bronchodilator treatment might aggravate SCD via their modulating effect on the a...

journal_title：Frontiers in physiology

authors： Bokov P,El Jurdi H,Denjoy I,Peiffer C,Medjahdi N,Holvoet L,Benkerrou M,Delclaux C

更新日期：2020-02-26 00:00:00

abstract：:We have isolated dental pulp cells (DPCs) from three healthy (hDPCs) and three carious (cDPCs) donors and shown that compared to hDPCs cells isolated from superficial carious lesions show higher clonogenic potential; show an equivalent proportion of cells with putative stem cell surface markers; show enhanced matrix m...

journal_title：Frontiers in physiology

authors： Alkharobi H,Beattie J,Meade J,Devine D,El-Gendy R

更新日期：2017-04-28 00:00:00

abstract：:Microvesicles (MVs) are released by most cell types in physiological conditions, but their number is often increased upon cellular activation or neoplastic transformation. This suggests that their detection may be helpful in pathological conditions to have information on activated cell types and, possibly, on the natu...

journal_title：Frontiers in physiology

authors： Colombo E,Borgiani B,Verderio C,Furlan R

更新日期：2012-03-29 00:00:00

abstract：:Primary aldosteronism (PA) is the most common cause of secondary hypertension. The paucity of good animal models hinders our understanding of the pathophysiology of PA and the hypertensive mechanism of PA remains incompletely known. It was recently reported that genetic deletion of TWIK-related acid-sensitive potassiu...

journal_title：Frontiers in physiology

authors： Shi L,Yuan F,Wang X,Wang R,Liu K,Tian Y,Guo Z,Zhang X,Wang S

更新日期：2019-11-22 00:00:00

abstract：:Apolipophorin III (ApoLp-III) is a well-known hemolymph protein having a functional role in lipid transport and immune responses of insects. Here we report the molecular and functional characterization of Anopheles stephensi Apolipophorin-III (AsApoLp-III) gene. This gene consists of 679 nucleotides arranged into two ...

journal_title：Frontiers in physiology

authors： Dhawan R,Gupta K,Kajla M,Kakani P,Choudhury TP,Kumar S,Kumar V,Gupta L

更新日期：2017-04-07 00:00:00

abstract：:Directed cell migration is essential all along an individual's life, from embryogenesis to tissue repair and cancer metastasis. Thus, due to its biomedical relevance, directed cell migration is currently under intense research. Directed cell migration has been shown to be driven by an assortment of external biasing cu...

journal_title：Frontiers in physiology

authors： Barriga EH,Theveneau E

更新日期：2020-11-25 00:00:00

abstract：:Gut-brain signaling controls feeding behavior and energy homeostasis; however, the underlying molecular mechanisms and impact of diet-induced obesity (DIO) on these pathways are poorly defined. We tested the hypothesis that elevated endocannabinoid activity at cannabinoid CB1 receptor (CB1Rs) in the gut of mice render...

journal_title：Frontiers in physiology

authors： Argueta DA,Perez PA,Makriyannis A,DiPatrizio NV

更新日期：2019-06-11 00:00:00

abstract：:Purpose: Aging is associated with changes in muscle energy metabolism. Proton (1H) and phosphorous (31P) magnetic resonance spectroscopy (MRS) has been successfully applied for non-invasive investigation of skeletal muscle metabolism. The aim of this study was to detect differences in adenosine triphosphate (ATP) prod...

journal_title：Frontiers in physiology

authors： Krumpolec P,Klepochová R,Just I,Tušek Jelenc M,Frollo I,Ukropec J,Ukropcová B,Trattnig S,Krššák M,Valkovič L

更新日期：2020-06-29 00:00:00

abstract：:Background: Periodontitis is a chronic inflammatory disease with a possible infectious component. Anemia of inflammation (AI) occurring in various chronic diseases alters the hemoglobin (Hb) concentration and iron status. Currently, the association between periodontitis and AI is still controversial. The aim of this s...

journal_title：Frontiers in physiology

authors： Wu D,Lin Z,Zhang S,Cao F,Liang D,Zhou X

更新日期：2020-01-31 00:00:00

abstract：:Rising atmospheric carbon dioxide (CO2) concentration is likely to influence insect-plant interactions. Aphid, as a typical phloem-feeding herbivorous insect, has shown consistently more positive responses in fitness to elevated CO2 concentrations than those seen in leaf-chewing insects. But, little is known about the...

journal_title：Frontiers in physiology

authors： Jiang S,Dai Y,Lu Y,Fan S,Liu Y,Bodlah MA,Parajulee MN,Chen F

更新日期：2018-11-12 00:00:00

abstract：:Background:Plutella xylostella has become a notorious pest of cruciferous crops all over the world. Delta-endotoxins of Bacillus thuringiensis are widely used insecticidal proteins for controlling P. xylostella. However, the interaction mechanism of B. thuringiensis with the immune system of P. xylostella, at the geno...

journal_title：Frontiers in physiology

authors： Li S,Xu X,Shakeel M,Xu J,Zheng Z,Zheng J,Yu X,Zhao Q,Jin F

更新日期：2018-11-15 00:00:00

abstract：:The study was conducted to compare and evaluate effects of four different macro-algaes on growth, immune response, and intestinal microbiota of Litopenaeus vannamei. In the rearing trial 1, shrimp were fed five diets containing four sources of macro-algaes for 8 weeks, named D1 (without macro-algae), D2 (Porphyra hait...

journal_title：Frontiers in physiology

authors： Niu J,Xie JJ,Guo TY,Fang HH,Zhang YM,Liao SY,Xie SW,Liu YJ,Tian LX

更新日期：2019-01-09 00:00:00

abstract：:The main objective of this study was to investigate the effects of the order of physical exercises on body composition, physical fitness, and cardiometabolic risk in adolescents participating in an interdisciplinary program focusing on the treatment of obesity. The final 12-week analyses involved 33 female adolescents...

journal_title：Frontiers in physiology

authors： Branco BHM,Valladares D,de Oliveira FM,Carvalho IZ,Marques DC,Coelho AA,de Oliveira LP,Bertolini SMMG

更新日期：2019-08-06 00:00:00

abstract：:Infants born premature are at increased risk for development of bronchopulmonary dysplasia (BPD), pulmonary hypertension (PH), and ultimately right ventricular (RV) dysfunction, which together carry a high risk of neonatal mortality. However, the role alveolar simplification and abnormal pulmonary microvascular develo...

journal_title：Frontiers in physiology

authors： Patel JR,Barton GP,Braun RK,Goss KN,Haraldsdottir K,Hopp A,Diffee G,Hacker TA,Moss RL,Eldridge MW

更新日期：2017-10-25 00:00:00

abstract：:Microgravity as well as chronic muscle disuse are two causes of low back pain originated at least in part from paraspinal muscle deconditioning. At present no study investigated the complexity of the molecular changes in human or mouse paraspinal muscles exposed to microgravity. The aim of this study was to evaluate l...

journal_title：Frontiers in physiology

authors： Gambara G,Salanova M,Ciciliot S,Furlan S,Gutsmann M,Schiffl G,Ungethuem U,Volpe P,Gunga HC,Blottner D

更新日期：2017-05-05 00:00:00

abstract：:The present study aims (1) to evaluate ratings of perceived exertion (RPE) and corresponding intensities during a maximal graded cycling test and (2) to determine the effects of 6 weeks of supramaximal cycling exercise (SCE) intervention on RPE and associated physiological factors in young and older sedentary groups. ...

journal_title：Frontiers in physiology

authors： Jabbour G,Majed L

更新日期：2018-10-25 00:00:00

abstract：:Inflammation is a process whose main function is to fight against invading pathogens or foreign agents. Nonetheless, it is widely accepted that inflammation takes part in multiple processes in a physiological or pathophysiological context. Among these processes the inflammation has been closely related to bone metabol...

journal_title：Frontiers in physiology

authors： Alonso-Pérez A,Franco-Trepat E,Guillán-Fresco M,Jorge-Mora A,López V,Pino J,Gualillo O,Gómez R

更新日期：2018-05-08 00:00:00

abstract：:The aim of this study was to analyze the relationship between alveolar bone deformation and β-catenin expression levels in response to the mechanical load changed by dental extraction in adult rats. Twenty-four male rats (Rattus norvegicus albinus), Wistar linage, at 2 months of age, were used. The right upper incisor...

journal_title：Frontiers in physiology

authors： Ferreira BC,Freire AR,Araujo R,do Amaral-Silva GK,Okamoto R,Prado FB,Rossi AC

更新日期：2020-06-05 00:00:00

abstract：:In the last three decades, all efforts in bone tissue engineering were driven by the dogma that the ideal pore size in bone substitutes lies between 0.3 and 0.5 mm in diameter. Newly developed additive manufacturing methodologies for ceramics facilitate the total control over pore size, pore distribution, bottleneck s...

journal_title：Frontiers in physiology

authors： Ghayor C,Weber FE

更新日期：2018-07-19 00:00:00

abstract：:The mechanisms of atrial fibrillation (AF) are a challenging research topic. The rotor hypothesis states that the AF is sustained by a reentrant wave that propagates around an unexcited core. Cardiac tissue heterogeneities, both structural and cellular, play an important role during fibrillatory dynamics, so that the ...

journal_title：Frontiers in physiology

authors： Ugarte JP,Tobón C,Lopes AM,Machado JAT

更新日期：2018-07-24 00:00:00

abstract：:Studies have revealed a robust and independent correlation between chronic kidney disease (CKD) and cardiovascular (CV) events, including death, heart failure, and myocardial infarction. Recent clinical trials extend this range of adverse CV events, including malignant ventricular arrhythmias and sudden cardiac death ...

journal_title：Frontiers in physiology

authors： Kiuchi MG,Ho JK,Nolde JM,Gavidia LML,Carnagarin R,Matthews VB,Schlaich MP

更新日期：2020-01-14 00:00:00

abstract：:Nutrition, via the insulin/insulin-like growth factor (IIS)/Target of Rapamycin (TOR) signaling pathway, can provide a strong molding force for determining animal size and shape. For instance, nutrition induces a disproportionate increase in the size of male horns in dung and rhinoceros beetles, or mandibles in stagho...

journal_title：Frontiers in physiology

authors： Koyama T,Mendes CC,Mirth CK

更新日期：2013-09-26 00:00:00

abstract：:The Subolesin/Akirin constitutes a good model for the study of functional evolution because these proteins have been conserved throughout the metazoan and play a role in the regulation of different biological processes. Here, we investigated the evolutionary history of Subolesin/Akirin with recent results on their str...

journal_title：Frontiers in physiology

authors： Artigas-Jerónimo S,Villar M,Cabezas-Cruz A,Valdés JJ,Estrada-Peña A,Alberdi P,de la Fuente J

更新日期：2018-11-13 00:00:00

abstract：:Troponin I (TnI) is a major regulator of cardiac muscle contraction and relaxation. During physiological and pathological stress, TnI is differentially phosphorylated at multiple residues through different signaling pathways to match cardiac function to demand. The combination of these TnI phosphorylations can exhibit...

journal_title：Frontiers in physiology

authors： Salhi HE,Hassel NC,Siddiqui JK,Brundage EA,Ziolo MT,Janssen PM,Davis JP,Biesiadecki BJ

更新日期：2016-12-15 00:00:00

abstract：:We have been able to reduce substantially patient pool heterogeneity by identifying phenotypic markers that allow the researcher to stratify chronic fatigue syndrome (CFS) patients into subgroups. To date, we have shown that stratifying based on the presence or absence of comorbid psychiatric diagnosis leads to a grou...

journal_title：Frontiers in physiology

authors： Natelson BH

更新日期：2013-05-20 00:00:00

abstract：:Background: In an aging population, regular physical activity (PA) and exercise have been recognized as important factors in maintaining physical function and thereby preventing loss of independence and disability. However, (older) adults spent the majority of their day sedentary and therefore insight into the consequ...

journal_title：Frontiers in physiology

authors： van der Velde JHPM,Savelberg HHCM,van der Berg JD,Sep SJS,van der Kallen CJH,Dagnelie PC,Schram MT,Henry RMA,Reijven PLM,van Geel TACM,Stehouwer CDA,Koster A,Schaper NC

更新日期：2017-04-25 00:00:00

abstract：:Intermittent hypoxia (IH), characterized as cyclic episodes of short-period hypoxia followed by normoxia, occurs in many physiological and pathophysiological conditions such as pregnancy, athlete, obstructive sleep apnea, and asthma. Hypoxia can induce autophagy, which is activated in response to protein aggregates, i...

journal_title：Frontiers in physiology

authors： Chang JC,Hu WF,Lee WS,Lin JH,Ting PC,Chang HR,Shieh KR,Chen TI,Yang KT

更新日期：2019-08-07 00:00:00