Adult-onset mitochondrial encephalopathy in association with the MT-ND3 T10158C mutation exhibits unique characteristics: A case report.

abstract：BACKGROUND:Squamous cell carcinoma of head and neck (SCCHN) is the fifth most common cancer worldwide. Inhibition of epidermal growth factor receptor signaling has been shown to be a critical component of therapeutic option. Herein, we report a case of durable complete response to erlotinib. CASE SUMMARY:An 81-year-ol...

journal_title：World journal of clinical cases

authors： Thinn MM,Hsueh CT,Hsueh CT

更新日期：2019-03-06 00:00:00

abstract：BACKGROUND:Coronavirus disease 2019 (COVID-19) is a major public health emergency with obvious characteristics of human-to-human transmission, and there are infective asymptomatic carriers. Early identification and proper management of patients with COVID-19 are important. Features in chest computed tomography (CT) can...

journal_title：World journal of clinical cases

authors： Chen LR,Chen ZX,Liu YC,Peng L,Zhang Y,Xu Q,Lin Q,Tao YM,Wu H,Yin S,Hu YJ

更新日期：2020-04-26 00:00:00

abstract：BACKGROUND:Penetrating brain injury (PBI) is an uncommon emergency in neurosurgery, and transorbital PBI is a rare type of PBI. Reasonable surgical planning and careful postoperative management can improve the prognosis of patients. CASE SUMMARY:The first case is a 68-year-old male patient who was admitted to the hosp...

journal_title：World journal of clinical cases

authors： Xue H,Zhang WT,Wang GM,Shi L,Zhang YM,Yang HF

更新日期：2020-01-26 00:00:00

abstract：:Chronic thromboembolic pulmonary hypertension (CTEPH) is a complex chronic disease in which pulmonary artery stenosis or obstruction caused by organized thrombus can lead to increased pulmonary artery pressure and pulmonary vascular resistance, ultimately triggering progressive right heart failure and death. Currently...

journal_title：World journal of clinical cases

authors： Jin Q,Zhao ZH,Luo Q,Zhao Q,Yan L,Zhang Y,Li X,Yang T,Zeng QX,Xiong CM,Liu ZH

更新日期：2020-07-06 00:00:00

abstract：:Chronic lymphocytic leukemia (CLL) is the most common leukemia in the western world. Despite significant advances in therapy over the last decade CLL remains incurable. Current front-line therapy often consists of chemoimmunotherapy-based regimens, most commonly the fludarabine, cyclophosphamide plus rituximab combina...

journal_title：World journal of clinical cases

authors： Crassini K,Mulligan SP,Best OG

更新日期：2015-08-16 00:00:00

abstract：BACKGROUND:Unilateral exophthalmos is often caused by inflammation, neoplasm, infection, metabolic disease, vascular disorder and several other less common conditions. Reflex sympathetic dystrophy related to unilateral exophthalmos has not been reported in the past literature. CASE SUMMARY:We describe a 45-year-old fe...

journal_title：World journal of clinical cases

authors： Wu CM,Liao HE,Hsu SW,Lan SJ

更新日期：2020-01-26 00:00:00

abstract：:Esophageal atresia with tracheo-oesophageal fistula (TEF) occurs in 1 in 3500 live births. Anorectal malformation is found to be associated with 14% of TEF. Esophageal atresia with TEF is a congenital anomaly which classically presents as excessive frothing from the mouth and respiratory distress. Rarely gastric posit...

journal_title：World journal of clinical cases

authors： Kamble RS,Gupta R,Gupta A,Kothari P,Dikshit KV,Kesan K,Mudkhedkar K

更新日期：2014-07-16 00:00:00

abstract：BACKGROUND:Breast cancer (BCa) is one of the most common malignancies in women; however, ureteral metastasis of BCa has rarely been reported in the literature. CASE SUMMARY:A 55-year-old Chinese woman with an 8-year history of BCa presented with lower back pain that had persisted for 3 mo. The patient underwent bilate...

journal_title：World journal of clinical cases

authors： Zhou ZH,Sun LJ,Zhang GM

更新日期：2019-10-26 00:00:00

abstract：INTRODUCTION:World Health Organization announced on April 2009 a public health emergency of international concern caused by swine-origin influenza A (H1N1) virus. Acute respiratory distress syndrome (ARDS) has been reported to be the most devastating complications of this pathogen. Extracorporeal membrane oxygenator (E...

journal_title：World journal of clinical cases

authors： Papadopoulos N,Martens S,Keller H,El-Sayed Ahmad A,Moritz A,Zierer A

更新日期：2014-10-16 00:00:00

abstract：:Autoimmune encephalitis is a poorly understood condition that can present with a combination of neurological and psychiatric symptoms, either of which may predominate. There are many autoantibodies associated with a variety of clinical syndromes - anti-N-Methyl-D-Aspartate receptor (NMDAR) is the commonest. Currently,...

journal_title：World journal of clinical cases

authors： Gough JL,Coebergh J,Chandra B,Nilforooshan R

更新日期：2016-08-16 00:00:00

abstract：BACKGROUND:Waldenström macroglobulinemia (WM) is a type of small lymphocytic lymphoma that mainly affects the bone marrow, spleen, and lymph nodes. A subset of patients with WM demonstrates extramedullary involvement (4.4%), and the most frequent extramedullary disease site involved is the lungs (30%). CASE SUMMARY:A ...

journal_title：World journal of clinical cases

authors： Zhao DF,Ning HY,Cen J,Liu Y,Qian LR,Han ZH,Shen JL

更新日期：2020-06-06 00:00:00

abstract：:Colorectal cancer (CRC) remains a major contributor to the number of cancer-related deaths that occur annually worldwide. With the development of molecular biology methods, an increasing number of molecular biomarkers have been identified and investigated. CRC is believed to result from an accumulation of epigenetic c...

journal_title：World journal of clinical cases

authors： Zhan YX,Luo GH

更新日期：2019-10-06 00:00:00

abstract：BACKGROUND:Sinusoidal obstruction syndrome (SOS) is a kind of rare liver disease which is characterized by damage to small hepatic vessels, affecting particularly the sinusoidal endothelium. Due to the special etiology and high mortality, early diagnosis of SOS is significant for clinical survival and prognosis. AIM:T...

journal_title：World journal of clinical cases

authors： Zhang Y,Jiang HY,Wei Y,Song B

更新日期：2019-09-26 00:00:00

abstract：BACKGROUND:Sinusoidal obstructive syndrome (SOS) is a disease that damages hepatic sinusoidal endothelial cells, resulting in progressive occlusion and fibrosis of the lobular central vein and the occurrence of intrahepatic sinusoidal portal hypertension. However, SOS after liver transplantation (LT) is uncommon and po...

journal_title：World journal of clinical cases

authors： Liu Y,Sun LY,Zhu ZJ,Wei L,Qu W,Zeng ZG

更新日期：2021-01-16 00:00:00

abstract：BACKGROUND:Idiopathic adulthood ductopenia (IAD) is a chronic cholestatic liver disease of unknown etiology that usually presents as unexplained jaundice. It is characterized by adult onset, lack of autoantibodies, inflammatory bowel disease and loss of interlobular bile ducts. CASE SUMMARY:This case presents a 27-yea...

journal_title：World journal of clinical cases

authors： Zhang XC,Wang D,Li X,Hu YL,Wang C

更新日期：2020-12-26 00:00:00

abstract：:In commenting on a case report of a 55-year-old man who suffered Takotsubo syndrome (TTS), in the setting of receiving chemotherapy with cytarabine and daunorubicin for acute myeloid leukemia, the author expresses his views that TTS in the setting of chemotherapy for malignancies may not be chemotherapeutic drug-speci...

journal_title：World journal of clinical cases

authors： Madias JE

更新日期：2015-02-16 00:00:00

abstract：BACKGROUND:Acute ischemic stroke (AIS) is mainly caused by cerebral blood flow disorders, which further leads to ischemic brain necrosis or encephalomalacia. The role of homocysteine (Hcy), an independent risk factor for cardiovascular disease, in the development of atherosclerosis is gradually revealed. However, studi...

journal_title：World journal of clinical cases

authors： Li J,Zhou F,Wu FX

更新日期：2019-11-26 00:00:00

abstract：BACKGROUND:In most cases, it is not difficult to differentiate common bile duct (CBD) stone from Ascaris infection because they are different disease entities and have different imaging findings. The two diseases usually demonstrate unique characteristic findings on computed tomography or magnetic resonance cholangiopa...

journal_title：World journal of clinical cases

authors： Choi SY,Jo HE,Lee YN,Lee JE,Lee MH,Lim S,Yi BH

更新日期：2020-10-06 00:00:00

abstract：:Idiopathic granulomatous mastitis is a rare chronic inflammatory lesion of the breast that can clinically and radiographically mimic breast carcinoma. The most common clinical presentation is an unilateral, discrete breast mass, nipple retraction and even a sinus formation often associated with an inflammation of the ...

journal_title：World journal of clinical cases

authors： Altintoprak F,Kivilcim T,Ozkan OV

更新日期：2014-12-16 00:00:00

abstract：:The current pandemic of coronavirus disease 2019 (COVID-19) which was first detected in Wuhan, China in December 2019 is caused by the novel coronavirus named severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). The virus has quickly spread to a large number of countries leading to a great number of deaths. U...

journal_title：World journal of clinical cases

authors： AlNaamani K,AlSinani S,Barkun AN

更新日期：2020-08-06 00:00:00

abstract：:The prevalence of nasopharyngeal carcinoma (NPC) is higher in southern China, Hong Kong, and Taiwan than in other areas in the world. Radiotherapy is an important part of treatment for NPC patients, especially those with stage III/IV disease. Subdural empyema is a rare but life-threatening complication in postradiothe...

journal_title：World journal of clinical cases

authors： Chen JC,Tan DH,Xue ZB,Yang SY,Li Y,Lai RL

更新日期：2018-11-26 00:00:00

abstract：BACKGROUND:Lymphoepithelioma-like carcinomas (LELCs) are rare, malignant epithelial tumors, generally considered a subtype of squamous cell carcinoma. LELCs are undifferentiated and can occur in multiple tissues, although LELCs in the urinary tract are extremely rare. As such, evidence does not provide clinicians with ...

journal_title：World journal of clinical cases

authors： Lai SC,Seery S,Zhang W,Liu M,Zhang G,Wang JY

更新日期：2020-02-26 00:00:00

abstract：BACKGROUND:Thrombotic thrombocytopenic purpura (TTP), a subtype of thrombotic microangiopathy, has a very high fatality rate if there is no timely diagnosis or treatment. Here, we report a case of TTP refractory to high displacement plasma exchange, which was later successfully treated with rituximab. CASE SUMMARY:Her...

journal_title：World journal of clinical cases

authors： Chen J,Jin JX,Xu XF,Zhang XX,Ye XN,Huang J

更新日期：2020-06-26 00:00:00

abstract：:Marjolin's ulcer (MU) represents malignant degeneration that typically ensues over a period of time in the post-burned lesions and scars or any other chronic wound. This review highlights various facets of the presentation and management of MUs that originate from post-burned lesions. The incidence of MUs in such lesi...

journal_title：World journal of clinical cases

authors： Saaiq M,Ashraf B

更新日期：2014-10-16 00:00:00

abstract：:Quorum sensing (QS) is cell communication that is widely used by bacterial pathogens to coordinate the expression of several collective traits, including the production of multiple virulence factors, biofilm formation, and swarming motility once a population threshold is reached. Several lines of evidence indicate tha...

journal_title：World journal of clinical cases

authors： Castillo-Juárez I,Maeda T,Mandujano-Tinoco EA,Tomás M,Pérez-Eretza B,García-Contreras SJ,Wood TK,García-Contreras R

更新日期：2015-07-16 00:00:00

abstract：BACKGROUND:Giant paraesophageal hiatal hernias (HH) are very infrequent, and their spectrum of clinical manifestations is large. Giant HH mainly occurs in elderly patients, and its relationship with anemia has been reported. For the surgical treatment of large HH, Nissen fundoplication is the most common antireflux pro...

journal_title：World journal of clinical cases

authors： Yasheng D,Wulamu W,Li YL,Tuhongjiang A,Abudureyimu K

更新日期：2020-03-26 00:00:00

abstract：:Targeted drug delivery to solid tumors is a very active research area, focusing mainly on improved drug formulation and associated best delivery methods/devices. Drug-targeting has the potential to greatly improve drug-delivery efficacy, reduce side effects, and lower the treatment costs. However, the vast majority of...

journal_title：World journal of clinical cases

authors： Kleinstreuer C,Feng Y,Childress E

更新日期：2014-12-16 00:00:00

abstract：BACKGROUND:Medical robot is a promising surgical tool, but no specific one has been designed for interventional treatment of chronic pain. We developed a computed tomography-image based navigation robot using a new registration method with binocular vision. This kind of robot is appropriate for minimal invasive interve...

journal_title：World journal of clinical cases

authors： Wang R,Han Y,Luo MZ,Wang NK,Sun WW,Wang SC,Zhang HD,Lu LJ

更新日期：2020-08-26 00:00:00

abstract：BACKGROUND:Squamous cell carcinoma antigen (SCCA) is regarded as a specific indicator of epithelial malignancies and is widely used in the diagnosis of squamous cell carcinoma (SCC). However, the expression of SCCA in gastric adenocarcinoma has not been studied in detail. CASE SUMMARY:A 52-year-old man was admitted to...

journal_title：World journal of clinical cases

authors： Wang L,Huang L,Xi L,Zhang SC,Zhang JX

更新日期：2020-10-06 00:00:00

abstract：:Gluten is one of the most abundant and widely distributed components of food in many areas. It can be included in wheat, barley, rye, and grains such as oats, barley, spelt, kamut, and triticale. Gluten-containing grains are widely consumed; in particular, wheat is one of the world's primary sources of food, providing...

journal_title：World journal of clinical cases

authors： Tovoli F,Masi C,Guidetti E,Negrini G,Paterini P,Bolondi L

更新日期：2015-03-16 00:00:00