Multichannel Silicon Probes for Awake Hippocampal Recordings in Large Animals.

abstract：:Auditory recognition memory in non-human primates differs from recognition memory in other sensory systems. Monkeys learn the rule for visual and tactile delayed matching-to-sample within a few sessions, and then show one-trial recognition memory lasting 10-20 min. In contrast, monkeys require hundreds of sessions to ...

journal_title：Frontiers in neuroscience

authors： Muñoz-López M,Insausti R,Mohedano-Moriano A,Mishkin M,Saunders RC

更新日期：2015-05-18 00:00:00

abstract：:Diffusion magnetic resonance imaging (dMRI) allows to reconstruct the main pathways of axons within the white matter of the brain as a set of polylines, called streamlines. The set of streamlines of the whole brain is called the tractogram. Organizing tractograms into anatomically meaningful structures, called tracts,...

journal_title：Frontiers in neuroscience

authors： Sharmin N,Olivetti E,Avesani P

更新日期：2018-02-06 00:00:00

abstract：:A vital feature in the success of Ecdysozoa is their ability to shed their exoskeleton (a process called ecdysis) such that they can grow or change their morphology. In holometabolous insects, these behaviors are orchestrated by the sequential actions of neuropeptides, one of which is crustacean cardioactive peptide (...

journal_title：Frontiers in neuroscience

authors： Lee D,Orchard I,Lange AB

更新日期：2013-11-05 00:00:00

abstract：:Understanding the effects of environmental stimulation in autism can improve therapeutic interventions against debilitating sensory overload, social withdrawal, fear and anxiety. Here, we evaluate the role of environmental predictability on behavior and protein expression, and inter-individual differences, in the valp...

journal_title：Frontiers in neuroscience

authors： Favre MR,La Mendola D,Meystre J,Christodoulou D,Cochrane MJ,Markram H,Markram K

更新日期：2015-06-02 00:00:00

abstract：:The prevalence of depressive disorders is growing worldwide, notably due to stagnation in the development of drugs with greater antidepressant efficacy, the continuous large proportion of patients who do not respond to conventional antidepressants, and the increasing rate of chronic medical conditions associated with ...

journal_title：Frontiers in neuroscience

authors： Vancassel S,Capuron L,Castanon N

更新日期：2018-07-24 00:00:00

abstract：:Investigation into the neural and computational bases of decision-making has proceeded in two parallel but distinct streams. Perceptual decision-making (PDM) is concerned with how observers detect, discriminate, and categorize noisy sensory information. Economic decision-making (EDM) explores how options are selected ...

journal_title：Frontiers in neuroscience

authors： Summerfield C,Tsetsos K

更新日期：2012-05-24 00:00:00

abstract：:We asked whether coordinated voluntary movement of the lower limbs could be regained in an individual having been completely paralyzed (>4 year) and completely absent of vision (>15 year) using two novel strategies-transcutaneous electrical spinal cord stimulation at selected sites over the spine as well as pharmacolo...

journal_title：Frontiers in neuroscience

authors： Gad P,Gerasimenko Y,Zdunowski S,Turner A,Sayenko D,Lu DC,Edgerton VR

更新日期：2017-06-08 00:00:00

abstract：:Donepezil is a potent acetylcholinesterase inhibitor, largely used worldwide to alleviate cognitive symptoms in Alzheimer's disease (AD). Beyond the widely described neuronal impact of donepezil, it was recently shown that targeting connexins, the proteins involved in astrocyte network organization, potentiates donepe...

journal_title：Frontiers in neuroscience

authors： Vidal B,Droguerre M,Valdebenito M,Zimmer L,Hamon M,Mouthon F,Charvériat M

更新日期：2020-08-12 00:00:00

abstract：:Spasticity is a common comorbidity associated with spinal cord injury (SCI). Robotic exoskeletons have recently emerged to facilitate legged mobility in people with motor complete SCI. Involuntary muscle activity attributed to spasticity, however, can prevent such individuals from using an exoskeleton. Specifically, a...

journal_title：Frontiers in neuroscience

authors： Ekelem A,Goldfarb M

更新日期：2018-06-01 00:00:00

abstract：:Spinal cord edema, mainly including vasogenic and cytotoxic edema, influences neurological outcome after spinal cord contusion (SCC). Aquaporin 4 (AQP4) is the most ubiquitous water channel in the central nervous system (CNS), which is a rate-limiting factor in vasogenic edema expressing in brain injury, and it contri...

journal_title：Frontiers in neuroscience

authors： Huang Y,Li SN,Zhou XY,Zhang LX,Chen GX,Wang TH,Xia QJ,Liang N,Zhang X

更新日期：2019-06-14 00:00:00

abstract：Background and Purpose:Oncological neurosurgery relies heavily on making continuous, intra-operative tumor-brain delineations based on image-guidance. Limitations of currently available imaging techniques call for the development of real-time image-guided resection tools, which allow for reliable functional and anatomi...

journal_title：Frontiers in neuroscience

authors： Soloukey S,Vincent AJPE,Satoer DD,Mastik F,Smits M,Dirven CMF,Strydis C,Bosch JG,van der Steen AFW,De Zeeuw CI,Koekkoek SKE,Kruizinga P

更新日期：2020-01-09 00:00:00

abstract：:Graph neural networks (GNN) rely on graph operations that include neural network training for various graph related tasks. Recently, several attempts have been made to apply the GNNs to functional magnetic resonance image (fMRI) data. Despite recent progresses, a common limitation is its difficulty to explain the clas...

journal_title：Frontiers in neuroscience

authors： Kim BH,Ye JC

更新日期：2020-06-30 00:00:00

abstract：:Objectives: This prospective cohort study explored whether two distinguished sensory parameters predicted acupuncture effects in chronic pain patients; namely high temporal summation of pain (TS) indicating spinal synaptic facilitation as well as a low vibration detection threshold (VDT) indicating a loss of Aβ-fiber ...

journal_title：Frontiers in neuroscience

authors： Baeumler PI,Conzen P,Irnich D

更新日期：2019-07-11 00:00:00

abstract：Objective:To evaluate the effects of long-term High-definition transcranial direct current stimulation (HD-tDCS) over precuneus on the level of consciousness (LOC) and the relationship between Mismatch negativity (MMN) and the LOC over the therapy period in patients with Disorders of consciousness (DOCs). Methods:We e...

journal_title：Frontiers in neuroscience

authors： Wang X,Guo Y,Zhang Y,Li J,Gao Z,Li Y,Zhou T,Zhang H,He J,Cong F

更新日期：2020-04-28 00:00:00

abstract：:Cryptotanshinone (CTN), a monomer compound extracted from the dried roots and rhizomes of Salvia miltiorrhiza Bge, has a variety of pharmacological effects. However, little research has been done on the mechanism of CTN in attenuating neuroinflammation. The present study aimed to investigate whether CTN can ameliorate...

journal_title：Frontiers in neuroscience

authors： Zhou Y,Wang X,Ying W,Wu D,Zhong P

更新日期：2019-08-21 00:00:00

abstract：:How speech signals are analyzed and represented remains a foundational challenge both for cognitive science and neuroscience. A growing body of research, employing various behavioral and neurobiological experimental techniques, now points to the perceptual relevance of both phoneme-sized (10-40 Hz modulation frequency...

journal_title：Frontiers in neuroscience

authors： Chait M,Greenberg S,Arai T,Simon JZ,Poeppel D

更新日期：2015-06-16 00:00:00

abstract：:Chronic glial activation is characterized by an increased number of activated microglia and astroglia; these secrete free radicals and cytotoxic cytokines, subsequently causing neuronal damage. This study investigated the hypothesis that a soy-lecithin based phytosomal curcumin formulation can decrease glial activatio...

journal_title：Frontiers in neuroscience

authors： Ullah F,Liang H,Niedermayer G,Münch G,Gyengesi E

更新日期：2020-03-12 00:00:00

abstract：:Defects in the endoplasmic reticulum (ER) membrane shaping and interaction with other organelles seem to be a crucial mechanism underlying Hereditary Spastic Paraplegia (HSP) neurodegeneration. REEP1, a transmembrane protein belonging to TB2/HVA22 family, is implicated in SPG31, an autosomal dominant form of HSP, and ...

journal_title：Frontiers in neuroscience

authors： Napoli B,Gumeni S,Forgiarini A,Fantin M,De Filippis C,Panzeri E,Vantaggiato C,Orso G

更新日期：2019-11-19 00:00:00

abstract：:Functional magnetic resonance imaging (fMRI) is a powerful noninvasive tool for studying spontaneous resting state functional connectivity (RSFC) in laboratory animals. Brain function can be significantly affected by generally used anesthetics, however, rendering the need for awake imaging. Only a few different awake ...

journal_title：Frontiers in neuroscience

authors： Stenroos P,Paasonen J,Salo RA,Jokivarsi K,Shatillo A,Tanila H,Gröhn O

更新日期：2018-08-20 00:00:00

abstract：:We review the role of oscillations in the brain and in the auditory system showing that the ability of humans to distinguish changes in pitch can be explained as a precise analysis of temporal information in auditory signals by neural oscillations. The connections between auditory brain stem chopper neurons construct ...

journal_title：Frontiers in neuroscience

authors： Bahmer A,Gupta DS

更新日期：2018-10-31 00:00:00

abstract：:A large body of experimental and clinical evidence has strongly suggested that monoamines play an important role in regulating epileptogenesis, seizure susceptibility, convulsions, and comorbid psychiatric disorders commonly seen in people with epilepsy (PWE). However, neither the relative significance of individual m...

journal_title：Frontiers in neuroscience

authors： Svob Strac D,Pivac N,Smolders IJ,Fogel WA,De Deurwaerdere P,Di Giovanni G

更新日期：2016-11-10 00:00:00

abstract：:Attention and working memory (WM) are core components of executive functions, and they can be enhanced by training. One activity that has shown to improve executive functions is musical training, but the brain networks underlying these improvements are not well known. We aimed to identify, using functional MRI (fMRI),...

journal_title：Frontiers in neuroscience

authors： Kausel L,Zamorano F,Billeke P,Sutherland ME,Larrain-Valenzuela J,Stecher X,Schlaug G,Aboitiz F

更新日期：2020-10-08 00:00:00

abstract：:Aromatase cytochrome P450arom (cyp19) is the only enzyme that has the ability to convert androgens into estrogens. Estrogens, which are produced locally in the vertebrate brain play many fundamental roles in neuroendocrine functions, reproductive functions, socio-sexual behaviors, and neurogenesis. Radial glial cells ...

journal_title：Frontiers in neuroscience

authors： Xing L,Esau C,Trudeau VL

更新日期：2016-01-12 00:00:00

abstract：:While brain stimulation techniques have been examined as treatment options for chronic tinnitus for many years, they have recently been extended to multimodal treatment approaches. As chronic tinnitus is often accompanied by comorbid muscular tension in the neck and back, we performed a one-arm pilot study to explore ...

journal_title：Frontiers in neuroscience

authors： Vielsmeier V,Schecklmann M,Schlee W,Kreuzer PM,Poeppl TB,Rupprecht R,Langguth B,Lehner A

更新日期：2018-02-20 00:00:00

abstract：:There is a need for reliable and objective measures of early and mild symptomology in multiple sclerosis (MS), as deficits can be subtle and difficult to quantify objectively in patients without overt physical deficits. We hypothesized that a speech-in-noise (SiN) task would be sensitive to demyelinating effects on pr...

journal_title：Frontiers in neuroscience

authors： Iva P,Fielding J,Clough M,White O,Godic B,Martin R,Rajan R

更新日期：2020-12-23 00:00:00

abstract：:Metabolic confusion has been linked to the pathogenesis of Parkinson's disease (PD), while the dynamic changes associated with the onset and progression of PD remain unclear. Herein, dynamic changes in metabolites were detected from the initiation to the development of 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPT...

journal_title：Frontiers in neuroscience

authors： Lu Y,Zhang X,Zhao L,Yang C,Pan L,Li C,Liu K,Bai G,Gao H,Yan Z

更新日期：2018-02-20 00:00:00

abstract：:A growing understanding of music therapy with patients with disorders of consciousness (DOC) has developed from observing behavioral changes and using these to gain new ways of experiencing this research environment and setting. Neuroscience provides further insight into the effects of music therapy; however, various ...

journal_title：Frontiers in neuroscience

authors： Vogl J,Heine AM,Steinhoff N,Weiss K,Tucek G

更新日期：2015-08-04 00:00:00

abstract：:Over the past several decades, clinical studies have shown significant analgesic effects of acupuncture. The efficacy of acupuncture treatment has improved with the recent development of nanoporous needles (PN), which are produced by modifying the needle surface using nanotechnology. Herein, we showed that PN at acupo...

journal_title：Frontiers in neuroscience

authors： Bae SJ,Lim J,Lee S,Choi H,Jang JH,Kim YK,Oh JY,Park JH,Jung HS,Chae Y,In SI,Park HJ

更新日期：2019-06-20 00:00:00

abstract：:Increasing evidence suggests that noncoding RNAs play key roles in cellular processes, particularly in the brain. The present study used RNA sequencing to identify the transcriptional landscape of two human neural progenitor cell lines, SK-N-SH and ReNcell CX, as they differentiate into human cortical projection neuro...

journal_title：Frontiers in neuroscience

authors： Hecht PM,Ballesteros-Yanez I,Grepo N,Knowles JA,Campbell DB

更新日期：2015-10-23 00:00:00

abstract：:A patient with early achalasia presented spontaneous strong rhythmic non-propulsive contractions at ~7/min, independent of swallows. Our aim was to evaluate characteristics of the rhythmic contractions, provide data on the structure of pacemaker cells in the esophagus and discuss a potential role for interstitial cell...

journal_title：Frontiers in neuroscience

authors： Chen JH,Wang XY,Liu LW,Yu W,Yu Y,Zhao L,Huizinga JD

更新日期：2013-05-21 00:00:00