Atypical Autoimmune Encephalitis With Neuropil Antibodies Against a Yet Unknown Epitope.

abstract：:Given the increasing use of regenerative free muscle flaps for various reconstructive procedures and neuroprosthetic applications, there is great interest and value in their enhanced regeneration, revascularization, and reinnervation for improved functional recovery. Here, we implant polyimide-based mircroelectrodes o...

journal_title：Frontiers in neurology

authors： Srinivasan S,Vyas K,McAvoy M,Calvaresi P,Khan OF,Langer R,Anderson DG,Herr H

更新日期：2019-03-22 00:00:00

abstract：OBJECTIVE:Tinnitus is a common symptom of hearing impairment. Patients who are bilaterally hard of hearing are often affected by tinnitus. However, they cannot undergo any of the standard tinnitus therapies, since they rely on hearing. Cochlear implantation (CI) used to treat severe hearing disabilities, such as bilate...

journal_title：Frontiers in neurology

authors： Knopke S,Szczepek AJ,Häussler SM,Gräbel S,Olze H

更新日期：2017-04-25 00:00:00

abstract：:Objective: To determine whether performance in a virtual spatial navigational task is poorer in persistent postural perceptual dizziness (PPPD) patients than in healthy volunteers and patients suffering other vestibular disorders. Methods: Subjects were asked to perform three virtual Morris water maze spatial navigati...

journal_title：Frontiers in neurology

authors： Breinbauer HA,Contreras MD,Lira JP,Guevara C,Castillo L,Ruëdlinger K,Muñoz D,Delano PH

更新日期：2020-01-09 00:00:00

abstract：:The purpose of this study was to evaluate whether it is possible to restore the high-frequency angular vestibulo-ocular reflex (aVOR) in patients suffering from a severe bilateral vestibulopathy (BV) and implanted with a vestibular implant prototype. Three patients (S1-3) participated in the study. They received a pro...

journal_title：Frontiers in neurology

authors： Guinand N,Van de Berg R,Cavuscens S,Ranieri M,Schneider E,Lucieer F,Kingma H,Guyot JP,Pérez Fornos A

更新日期：2017-11-14 00:00:00

abstract：:The electrophysiological EEG features such as high frequency oscillations, spikes and functional connectivity are often used for delineation of epileptogenic tissue and study of the normal function of the brain. The epileptogenic activity is also known to be suppressed by cognitive processing. However, differences bet...

journal_title：Frontiers in neurology

authors： Cimbalnik J,Pail M,Klimes P,Travnicek V,Roman R,Vajcner A,Brazdil M

更新日期：2020-10-27 00:00:00

abstract：:A carotid-jugular fistula is a direct communication between the carotid artery and the jugular vein. Both congenital and spontaneous internal carotid-jugular fistulas are extremely rare. We describe the first case of successful endovascular treatment for a congenital internal carotid-jugular fistula. We report a 64-ye...

journal_title：Frontiers in neurology

authors： Wang M,Fan W,Mungur R,Gu J,Wan S

更新日期：2018-12-18 00:00:00

abstract：:When the diagnosis of myasthenia gravis (MG) has been secured, the aim of management should be prompt symptom control and the induction of remission or minimal manifestations. Symptom control, with acetylcholinesterase inhibitors such as pyridostigmine, is commonly employed. This may be sufficient in mild disease. The...

journal_title：Frontiers in neurology

authors： Farrugia ME,Goodfellow JA

更新日期：2020-07-07 00:00:00

abstract：Objective:To investigate the correlation between initial response to antiepileptic drugs (AEDs) and long-term outcomes after 3 years in patients with newly diagnosed epilepsy. Methods:This prospective study included 204 patients with newly diagnosed epilepsy, who were followed-up for at least 36 months. The long-term ...

journal_title：Frontiers in neurology

authors： Xia L,Ou S,Pan S

更新日期：2017-12-08 00:00:00

abstract：BACKGROUND:The present review investigated which findings in vascular imaging techniques can be used to predict clinical outcome and the risk of symptomatic intracerebral hemorrhage (sICH) in patients who underwent intravenous thrombolytic treatment. METHODS:Publications were searched, and the inclusion criteria were ...

journal_title：Frontiers in neurology

authors： Nogueira RC,Bor-Seng-Shu E,Saeed NP,Teixeira MJ,Panerai RB,Robinson TG

更新日期：2016-05-18 00:00:00

abstract：:Background: This study aims to investigate the association between blood pressure (BP) at the time of recanalization and hemorrhagic transformation in large vessel occlusion (LVO) patients following mechanical thrombectomy (MT) with general anesthesia. Methods: We retrospectively reviewed our data base for patients wi...

journal_title：Frontiers in neurology

authors： Cheng H,Xu C,Jin X,Chen Y,Zheng X,Shi F,He X,Hao Y,Jiang Y,Zhang J,Chen Z

更新日期：2020-11-17 00:00:00

abstract：:GLUT1 Deficiency Syndrome (GLUT1-DS) is a rare and potentially treatable neurometabolic condition, caused by a reduced glucose transport into the brain and clinically characterized by an epileptic encephalopathy with movement disorders. A wide inter-intrafamilial phenotypic variability has been reported. Very-long-cha...

journal_title：Frontiers in neurology

authors： Musumeci O,Ferlazzo E,Rodolico C,Gambardella A,Gagliardi M,Aguglia U,Toscano A

更新日期：2020-06-23 00:00:00

abstract：Background:Wernicke's encephalopathy (WE), a metabolic disorder due to thiamine deficiency, manifests with various neurological symptoms and signs. It has been known as a cause of vestibular dysfunction. Preliminary reports have proposed predominant involvement of the horizontal semicircular canals (HSCs). Objective:T...

journal_title：Frontiers in neurology

authors： Lee SH,Kim SH,Kim JM,Tarnutzer AA

更新日期：2018-03-12 00:00:00

abstract：:Introduction: Recent studies of patients with multiple sclerosis (MS) have revealed disturbances in distinct components of social cognition, such as impaired mentalizing and empathy. The present study investigated this socio-cognitive profile in MS patients in more detail, by examining their performance on tasks measu...

journal_title：Frontiers in neurology

authors： Czekóová K,Shaw DJ,Saxunová K,Dufek M,Mareček R,Vaníček J,Brázdil M

更新日期：2019-05-21 00:00:00

abstract：:Background: Gait disorders (GD) are frequent and disabling symptoms in patients with Parkinson's disease, mostly because they significantly limit mobility and often lead to fear of falls or actual falls. Nowadays, rehabilitation is considered to be the most effective nonpharmacological approach to reduce risk of falls...

journal_title：Frontiers in neurology

authors： Kosutzka Z,Kusnirova A,Hajduk M,Straka I,Minar M,Valkovic P

更新日期：2019-09-24 00:00:00

abstract：:Approaches to furthering our understanding of the bioeffects, behavioral changes, and treatment options following exposure to blast are a worldwide priority. Of particular need is a more concerted effort to employ animal models to determine possible sex differences, which have been reported in the clinical literature....

journal_title：Frontiers in neurology

authors： McCabe JT,Tucker LB

更新日期：2020-09-30 00:00:00

abstract：:Sleep complaints increase profoundly with age; prevalence estimates of insomnia in the elderly reach up to 37%. The three major types of nocturnal complaints are difficulties initiating (DIS) and maintaining (DMS) sleep and early morning awakening (EMA), of which the latter appears most characteristic for aging. The n...

journal_title：Frontiers in neurology

authors： Stoffers D,Moens S,Benjamins J,van Tol MJ,Penninx BW,Veltman DJ,Van der Wee NJ,Van Someren EJ

更新日期：2012-06-28 00:00:00

abstract：:Background: Diagnosing stroke as a cause of acute vertigo, dizziness, or double vision remains a challenge, because symptom characteristics can be variable. The purpose of this study was to prospectively investigate lesion-symptom relationships in patients with acute vestibular or ocular motor stroke. Methods: Three h...

journal_title：Frontiers in neurology

authors： Zwergal A,Möhwald K,Salazar López E,Hadzhikolev H,Brandt T,Jahn K,Dieterich M

更新日期：2020-08-06 00:00:00

abstract：:Background: Caregiver strain is recognized globally with Parkinson's disease (PD). Comparatively little is understood about caregiver burden and strain in Asia. Objective: To investigate caregiver strain for families living with PD in Singapore, in light of international data. Methods: Ninety-four caregivers were recr...

journal_title：Frontiers in neurology

authors： Tan SB,Williams AF,Tan EK,Clark RB,Morris ME

更新日期：2020-06-23 00:00:00

abstract：BACKGROUND AND PURPOSE:The aim of this study was to systematically review the efficacy and tolerability of gabapentin in the treatment of sleep disturbance in patients with medical illness. METHODS:PubMed was searched for randomized, double-blinded, placebo-controlled trials that reported sleep changes during gabapent...

journal_title：Frontiers in neurology

authors： Liu GJ,Karim MR,Xu LL,Wang SL,Yang C,Ding L,Wang YF

更新日期：2017-07-14 00:00:00

abstract：:The developmental vulnerability of different classes of axonal pathways in preterm white matter is not known. We propose that laminar compartments of the developing cerebral wall serve as spatial framework for axonal growth and evaluate potential of anatomical landmarks for understanding reorganization of the cerebral...

journal_title：Frontiers in neurology

authors： Kostović I,Kostović-Srzentić M,Benjak V,Jovanov-Milošević N,Radoš M

更新日期：2014-07-29 00:00:00

abstract：:Epilepsy may reflect a focal abnormality of cerebral tissue, but the generation of seizures typically involves propagation of abnormal activity through cerebral networks. We examined epileptiform discharges (spikes) with dense array electroencephalography (dEEG) in five patients to search for the possible engagement o...

journal_title：Frontiers in neurology

authors： Song J,Tucker DM,Gilbert T,Hou J,Mattson C,Luu P,Holmes MD

更新日期：2013-05-15 00:00:00

abstract：:Noradrenaline, one of the main brain monoamines, has powerful central influences on forebrain neurobiological processes which support the mental activities occurring during the sleep-waking cycle. Noradrenergic neurons are activated during waking, decrease their firing rate during slow wave sleep, and become silent du...

journal_title：Frontiers in neurology

authors： Gottesmann C

更新日期：2011-12-12 00:00:00

abstract：:The vestibular system plays a crucial role in maintaining postural balance. Unilateral vestibular lesions result in a typical syndrome characterized by postural imbalance, altered locomotor patterns and gaze stabilization, as well as cognitive and neurovegetative disorders. One of the main difficulties encountered in ...

journal_title：Frontiers in neurology

authors： Marouane E,Rastoldo G,El Mahmoudi N,Péricat D,Chabbert C,Artzner V,Tighilet B

更新日期：2020-05-29 00:00:00

abstract：INTRODUCTION:In tinnitus treatment, there is a tendency to shift from a "one size fits all" to a more individual, patient-tailored approach. Insight in the heterogeneity of the tinnitus spectrum might improve the management of tinnitus patients in terms of choice of treatment and identification of patients with severe ...

journal_title：Frontiers in neurology

authors： van den Berge MJC,Free RH,Arnold R,de Kleine E,Hofman R,van Dijk JMC,van Dijk P

更新日期：2017-04-03 00:00:00

abstract：:Background and Purpose: The relationship between cerebral microbleeds (CMBs) and prognosis in patients with ischemic stroke is still unclear. Our aim here was to verify the relationship between CMBs and functional outcomes in patients with minor ischemic stroke treated with antiplatelet therapy. Methods: We retrospect...

journal_title：Frontiers in neurology

authors： Sakuta K,Yaguchi H,Sato T,Komatsu T,Sakai K,Mitsumura H,Matsushima S,Iguchi Y

更新日期：2020-06-16 00:00:00

abstract：:Background: Most travelers experience Jet Lag Disorder (JLD) symptoms due to misalignment of their circadian rhythms with respect to the new time zone. We assessed the efficacy and safety of tasimelteon (HETLIOZ®) in healthy participants using a laboratory model of JLD induced by an 8-h phase advance of the sleep-wake...

journal_title：Frontiers in neurology

authors： Polymeropoulos CM,Mohrman MA,Keefe MS,Brzezynski JL,Wang J,Prokosch LS,Polymeropoulos VM,Xiao C,Birznieks G,Polymeropoulos MH

更新日期：2020-07-09 00:00:00

abstract：:Background: Palliative care in Parkinson's Disease (PD) patients considerably differs from palliative care in oncology patients. Integrated care models are a concept to support patients and improve management of PD symptoms. However, it is not known if the access to PD patients at the end of life can be achieved throu...

journal_title：Frontiers in neurology

authors： Eggers C,Dano R,Schill J,Fink GR,Timmermann L,Voltz R,Golla H,Lorenzl S

更新日期：2018-07-30 00:00:00

abstract：:Lifestyle factors such as intellectual stimulation, cognitive and social engagement, nutrition, and various types of exercise appear to reduce the risk for common age-associated disorders such as Alzheimer's disease (AD) and vascular dementia. In fact, many studies have suggested that promoting physical activity can h...

journal_title：Frontiers in neurology

authors： Foster PP,Rosenblatt KP,Kuljiš RO

更新日期：2011-05-06 00:00:00

abstract：:Background: Agoraphobia was described in 1871 as a condition of fear-related alterations in spatial orientation and locomotor control triggered by places or situations that might cause a patient to panic and feel trapped. In contemporary nosology, however, this original concept of agoraphobia was split into two diagno...

journal_title：Frontiers in neurology

authors： Indovina I,Conti A,Lacquaniti F,Staab JP,Passamonti L,Toschi N

更新日期：2019-08-13 00:00:00

abstract：:Background: Over the last few years there has been growing interest in use of visual measures as useful tools for multiple sclerosis (MS) prognosis and tracking. Optic neuritis (ON) being a prevalent and often-presenting symptom of the disease, as well as the high occurrence rate of posterior visual system damage inde...

journal_title：Frontiers in neurology

authors： Backner Y,Petrou P,Glick-Shames H,Raz N,Zimmermann H,Jost R,Scheel M,Paul F,Karussis D,Levin N

更新日期：2019-05-03 00:00:00