The Management of Pilonidal Sinus.

abstract：BACKGROUND:The risk of venous thromboembolism (VTE) is 4 to 7 times higher in cancer patients than in the normal population. Moreover, cancer patients who take anticoagulants suffer more frequently from hemorrhagic complications and VTE recurrences. Patients often find low-molecular-weight heparin (LMWH) treatment unpl...

journal_title：Deutsches Arzteblatt international

authors： Beyer-Westendorf J,Klamroth R,Kreher S,Langer F,Matzdorff A,Riess H

更新日期：2019-01-18 00:00:00

abstract：BACKGROUND:Clostridium difficile infections are becoming more common, more severe, and more likely to recur. Conventional treatment with antibiotics often fails to eradicate the infection; even when it succeeds, recurrent infection is common. Complementary treatment with probiotic agents to reconstitute the physiologic...

journal_title：Deutsches Arzteblatt international

authors： Kleger A,Schnell J,Essig A,Wagner M,Bommer M,Seufferlein T,Härter G

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND:Otitis externa has a lifetime prevalence of 10% and can arise in acute, chronic, and necrotizing forms. METHODS:This review is based on publications retrieved by a selective search of the pertinent literature. RESULTS:The treatment of acute otitis media consists of anal- gesia, cleansing of the external au...

journal_title：Deutsches Arzteblatt international

authors： Wiegand S,Berner R,Schneider A,Lundershausen E,Dietz A

更新日期：2019-03-29 00:00:00

abstract：BACKGROUND:Psychiatric emergencies such as acute psychomotor agitation or suicidality often arise in non-psychiatric settings such as general hospitals, emergency services, or doctors' offices and give rise to stress for all persons involved. They may be life-threatening and must therefore be treated at once. In this a...

journal_title：Deutsches Arzteblatt international

authors： Mavrogiorgou P,Brüne M,Juckel G

更新日期：2011-04-01 00:00:00

abstract：INTRODUCTION:The choice of type of heart valve prosthesis is determined by the patient's age since bioprostheses have a limited lifespan. This article reviews current recommendations and the literature on cardiac valve replacement. METHODS:Selective literature search in Medline/PubMed back to 1996 and review of curren...

journal_title：Deutsches Arzteblatt international

authors： Hoffmann G,Lutter G,Cremer J

更新日期：2008-02-01 00:00:00

abstract：BACKGROUND:Habitually shortened nighttime sleep is a common phenomenon in childhood and adolescence, sometimes associated with chronic sleep reduction (CSR). CSR is associated with impairments of performance ability and emotional well-being. The extent to which children and adolescents in Germany suffer from CSR is unc...

journal_title：Deutsches Arzteblatt international

authors： Paschke K,Laurenz L,Thomasius R

更新日期：2020-10-02 00:00:00

abstract：BACKGROUND:Although the number of elderly patients with fractures is increasing, there have been only a few studies to date of the efficacy of collaborative treatment by trauma surgeons and geriatricians. METHODS:Data on patients over age 75 with femoral neck, trochanteric, proximal humeral, and pelvic ring fractures ...

journal_title：Deutsches Arzteblatt international

authors： Grund S,Roos M,Duchene W,Schuler M

更新日期：2015-02-13 00:00:00

abstract：BACKGROUND:Cirrhosis of the liver is the end stage of chronic liver disease. Among the many liver disorders that can lead to cirrhosis, some progress rapidly (years) and others more slowly (decades). In Germany, cirrhosis is often a consequence of fatty liver disease due to alcoholism or other causes, but can also be c...

journal_title：Deutsches Arzteblatt international

authors： Wiegand J,Berg T

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND:When reading reports of medical research findings, one is usually confronted with p-values. Publications typically contain not just one p-value, but an abundance of them, mostly accompanied by the word "significant." This article is intended to help readers understand the problem of multiple p-values and how...

journal_title：Deutsches Arzteblatt international

authors： Victor A,Elsässer A,Hommel G,Blettner M

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Despite sparse documentation of their long-term therapeutic effects and side effects, antipsychotic drugs have come to be prescribed more frequently for children and adolescents in recent years, both in the USA and in Europe. No current data are available about antipsychotic prescriptions for this age group ...

journal_title：Deutsches Arzteblatt international

authors： Bachmann CJ,Lempp T,Glaeske G,Hoffmann F

更新日期：2014-01-17 00:00:00

abstract：BACKGROUND:Nail disorders can arise at any age. About half of all nail disorders are of infectious origin, 15% are due to inflammatory or metabolic conditions, and 5% are due to malignancies and pigment disturbances. The differential diagnosis of nail disorders is often an area of uncertainty. METHODS:This review is b...

journal_title：Deutsches Arzteblatt international

authors： Wollina U,Nenoff P,Haroske G,Haenssle HA

更新日期：2016-07-25 00:00:00

abstract：INTRODUCTION:The purpose of this article is to present the results of microsurgical clipping or endovascular coil obliteration of unruptured intracranial aneurysms (UIA), in a single cerebrovascular center with regard to successful obliteration and periprocedural complications. METHODS:Data concerning patients with UI...

journal_title：Deutsches Arzteblatt international

authors： Seifert V,Gerlach R,Raabe A,Güresir E,Beck J,Szelényi A,Setzer M,Vatter H,Du Mesnil de Rochemont R,Zanella F,Sitzer M,Berkefeld J

更新日期：2008-06-01 00:00:00

abstract：BACKGROUND:Medication reviews and medication management are being used more and more around the world to improve medication safety. Both of these tools were originally conceived as pharmaceutical care activities and have recently been developed into interdisciplinary approaches. We studied the efficacy of interprofessi...

journal_title：Deutsches Arzteblatt international

authors： Köberlein-Neu J,Mennemann H,Hamacher S,Waltering I,Jaehde U,Schaffert C,Rose O

更新日期：2016-11-04 00:00:00

abstract：BACKGROUND:The histomorphological changes of lung damage in severe coronavirus disease 2019 (COVID-19) have not yet been adequately characterized. In this article, we describe the sequence of pathological changes in COVID-19 and discuss the implications for approaches to treatment. METHODS:Standardized autopsies were ...

journal_title：Deutsches Arzteblatt international

authors： Kommoss FKF,Schwab C,Tavernar L,Schreck J,Wagner WL,Merle U,Jonigk D,Schirmacher P,Longerich T

更新日期：2020-07-20 00:00:00

abstract：BACKGROUND:The German Standing Committee on Vaccination (STIKO) recommends vaccination against human papillomaviruses (HPV) of the high-risk types 16 and 18. The duration of protection afforded by HPV vaccines has been reported in multiple studies to date but has not been systematically evaluated. METHOD:Systematic li...

journal_title：Deutsches Arzteblatt international

authors： Deleré Y,Wichmann O,Klug SJ,van der Sande M,Terhardt M,Zepp F,Harder T

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:The treatment of pregnant women who have illnesses unrelated to pregnancy can cause uncertainty among physicians. METHODS:We searched the PubMed database and specialty guidelines from Germany and abroad (the guidelines of the German Society for Gynecology and Obstetrics, the American Congress of Obstetri ci...

journal_title：Deutsches Arzteblatt international

authors： Bolz M,Körber S,Reimer T,Buchmann J,Schober HC,Briese V

更新日期：2017-09-15 00:00:00

abstract：BACKGROUND:High-altitude travel, for mountain climbing, trekking, or sightseeing, has become very popular. Therefore, the awareness of its dangers has increased, and many prospective travelers seek medical advice before setting forth on their trip. METHODS:We selectively searched the literature for relevant original a...

journal_title：Deutsches Arzteblatt international

authors： Schommer K,Bärtsch P

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:Most women of child-bearing age want a safe method of contraception. Numerous methods are available, with different modes of application. In situations involving particular risks, the selection of the right method poses a special challenge. METHODS:Contraceptive methods for use in various situations with in...

journal_title：Deutsches Arzteblatt international

authors： Römer T

更新日期：2019-11-08 00:00:00

abstract：BACKGROUND:In endocrine orbitopathy (EO), disfiguring proptosis and diplopia impair patients' quality of life both at home and at work. METHODS:From late 2006 to the beginning of 2008, 250 outpatients in an interdisciplinary thyroid and eye clinic filled out a questionnaire about their quality of life, occupational di...

journal_title：Deutsches Arzteblatt international

authors： Ponto KA,Pitz S,Pfeiffer N,Hommel G,Weber MM,Kahaly GJ

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND:The regional prevalence of risk factors can vary over time. The Study of Health in Pomerania (SHIP) addresses prevalence trends for common risk factors in a region in northeast Germany. METHODS:A longitudinal study was carried out from 1997 to 2001 (SHIP-0, with 4308 subjects), and a second, independent ran...

journal_title：Deutsches Arzteblatt international

authors： Völzke H,Ittermann T,Schmidt CO,Baumeister SE,Schipf S,Alte D,Biffar R,John U,Hoffmann W

更新日期：2015-03-13 00:00:00

abstract：BACKGROUND:As of 1 April 2007, pharmacists in Germany filling prescriptions covered by the statutory health insurance system (Gesetzliche Krankenversicherung, GKV) are required, whenever possible, to dispense a preparation that contains the same active substance and for which a rebate contract is in effect. The physici...

journal_title：Deutsches Arzteblatt international

authors： Hoffmann F,Glaeske G,Pfannkuche MS

更新日期：2009-11-01 00:00:00

abstract：INTRODUCTION:Autopsy studies of persons who died of cancer have shown the lungs to be the sole site of metastasis in about 20% of cases. The resection of pulmonary metastases is indicated for palliative purposes if they contain a large volume of necrotic tumor, infiltrate the thoracic wall to produce pain, or cause hem...

journal_title：Deutsches Arzteblatt international

authors： Pfannschmidt J,Egerer G,Bischof M,Thomas M,Dienemann H

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Lung transplantation is the final treatment option in the end stage of certain lung diseases, once all possible conservative treatments have been exhausted. Depending on the indication for which lung transplantation is performed, it can improve the patient's quality of life (e.g., in emphysema) and/ or prolo...

journal_title：Deutsches Arzteblatt international

authors： Hartert M,Senbaklavacin O,Gohrbandt B,Fischer BM,Buhl R,Vahld CF

更新日期：2014-02-14 00:00:00

abstract：BACKGROUND:In this study, we investigated the measures currently being taken in German hospitals to prevent infection with methicillin-resistant strains of Staphylococcus aureus (MRSA). To this end, we circulated a questionnaire among hospitals participating in the MRSA-KISS module. "KISS" in the name of this project s...

journal_title：Deutsches Arzteblatt international

authors： Chaberny IF,Wriggers A,Behnke M,Gastmeier P

更新日期：2010-09-01 00:00:00

abstract：INTRODUCTION:Data on the prevalence and regional distribution of the metabolic syndrome in Germany are lacking, in particular for primary care. METHODS:In October 2005 anthropometric measurements were taken from 35 869 consecutive patients aged 18 to 99 years, in 1511 primary care practices. Waist circumference, blood...

journal_title：Deutsches Arzteblatt international

authors： Moebus S,Hanisch J,Bramlage P,Lösch C,Hauner H,Wasem J,Jöckel KH

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND:The many varieties of cystic pancreatic tumor, and especially intraductal papillary mucinous neoplasia (IPMN), have attracted increased attention recently. Their incidence may be rising, and their histopathological evaluation and classification have become more precise than before. METHODS:We discuss the cu...

journal_title：Deutsches Arzteblatt international

authors： Grützmann R,Post S,Saeger HD,Niedergethmann M

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND:The treatment options for bcr-abl positive chronic myelogenous leukemia (CML) include chemotherapy, immune therapy, allogeneic stem cell transplantation, and molecular therapy. The tyrosine kinase inhibitor imatinib was approved for the treatment of CML in 2002. Data from clinical trials allow a comparison o...

journal_title：Deutsches Arzteblatt international

authors： von Bubnoff N,Duyster J

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND:Few reliable data are available on the epidemiology and treatment of spontaneous pneumothorax. We studied the sex and age distribution, frequency of hospitalization, mortality, and conservative versus surgical care of this condition in Germany in order to draw well-founded conclusions about its in-hospital d...

journal_title：Deutsches Arzteblatt international

authors： Schnell J,Koryllos A,Lopez-Pastorini A,Lefering R,Stoelben E

更新日期：2017-11-03 00:00:00

abstract：BACKGROUND:Monoclonal antibodies (mAb) and fusion proteins (FP) are increasingly being used in children and adolescents. In this review, we analyze the evidence for their safety and efficacy in the treatment of the most common chronic inflammatory diseases. METHODS:We systematically searched PubMed, AWMF.org, and othe...

journal_title：Deutsches Arzteblatt international

authors： Niehues T,Özgür TT

更新日期：2019-10-18 00:00:00

abstract：BACKGROUND:Patients with ovarian cancer usually present to a family physician with nonspecific symptoms, most often abdominal pain. The outcome depends above all on the stage of the disease when it is diagnosed and on the quality of treatment. METHODS:This article is based on a review of selected publications from 200...

journal_title：Deutsches Arzteblatt international

authors： Burges A,Schmalfeldt B

更新日期：2011-09-01 00:00:00