Glutamatergic Dysfunction and Glutamatergic Compounds for Major Psychiatric Disorders: Evidence From Clinical Neuroimaging Studies.

abstract：:Introduction: People with psychosis show impairments in cognitive flexibility, a phenomenon that is still poorly understood. In this study, we tested if there were differences in cognitive and metacognitive processes related to rigidity in patients with psychosis. We compared individuals with dichotomous interpersonal...

journal_title：Frontiers in psychiatry

authors： García-Mieres H,Usall J,Feixas G,Ochoa S

更新日期：2020-11-26 00:00:00

abstract：:Background: Major depressive disorder (MDD) is associated with a wide range of cognitive deficits. However, it remains unclear whether there will be a major cognitive deficit independently caused by depression at acute episodes of MDD. Method: A comprehensive neurocognitive test battery was used to assess the executiv...

journal_title：Frontiers in psychiatry

authors： Liu J,Dong Q,Lu X,Sun J,Zhang L,Wang M,Wan P,Guo H,Zhao F,Ju Y,Yan D,Li H,Fang H,Guo W,Liao M,Zhang X,Zhang Y,Liu B,Li L

更新日期：2019-11-12 00:00:00

abstract：:Abnormalities in EEG gamma band oscillations (GBO, 30-80 Hz) serve as a prominent biomarker of schizophrenia (Sz), associated with positive, negative, and cognitive symptoms. Chronic, subanesthetic administration of antagonists of N-methyl-D-aspartate receptors (NMDAR), such as ketamine, elicits behavioral effects, an...

journal_title：Frontiers in psychiatry

authors： McNally JM,McCarley RW,Brown RE

更新日期：2013-09-17 00:00:00

abstract：:Autism spectrum condition (ASC) is recognized as having an inflammatory component. Post-mortem brain samples from patients with ASC display neuroglial activation and inflammatory markers in cerebrospinal fluid, although little is known about the underlying molecular mechanisms. Nuclear factor kappa-light-chain-enhance...

journal_title：Frontiers in psychiatry

authors： Young AM,Campbell E,Lynch S,Suckling J,Powis SJ

更新日期：2011-05-13 00:00:00

abstract：:Attention deficit hyperactivity disorder (ADHD) is a disorder most frequently diagnosed in children and adolescents. Although ADHD can be effectively treated with psychostimulants, a significant proportion of patients discontinue treatment because of adverse events or insufficient improvement of symptoms. In addition,...

journal_title：Frontiers in psychiatry

authors： Sierawska A,Prehn-Kristensen A,Moliadze V,Krauel K,Nowak R,Freitag CM,Siniatchkin M,Buyx A

更新日期：2019-05-16 00:00:00

abstract：Background:Past studies using the Bonn Scale for the Assessment of Basic Symptoms (hereafter, Bonn Scale) have shown that self-reported perceptual/cognitive disturbances reveal which persons have or will soon develop schizophrenia. Here, we focused specifically on the clinical value of self-reported visual perceptual a...

journal_title：Frontiers in psychiatry

authors： Keane BP,Cruz LN,Paterno D,Silverstein SM

更新日期：2018-03-12 00:00:00

abstract：Objectives:Deviations from typical word use have been previously reported in clinical depression, but language patterns of mild depression (MD), as distinct from normal sadness (NS) and euthymic state, are unknown. In this study, we aimed to apply the linguistic approach as an additional diagnostic key for understandin...

journal_title：Frontiers in psychiatry

authors： Smirnova D,Cumming P,Sloeva E,Kuvshinova N,Romanov D,Nosachev G

更新日期：2018-04-10 00:00:00

abstract：Background:Previous studies have revealed the efficacy of metacognitive training for schizophrenia. However, the underlying mechanisms of metacognitive training on brain function alterations, including the default-mode network (DMN), remain unknown. The present study explored treatment effects of metacognitive training...

journal_title：Frontiers in psychiatry

authors： Shan X,Liao R,Ou Y,Ding Y,Liu F,Chen J,Zhao J,Guo W,He Y

更新日期：2020-03-27 00:00:00

abstract：:Major depression is a psychiatric disorder with high prevalence in the general population, with increasing expression in adolescence, about 14% in young people. Frequently, it presents as a chronic condition, showing no remission even after several pharmacological treatments and persisting in adult life. Therefore, di...

journal_title：Frontiers in psychiatry

authors： Galvão-Coelho NL,Galvão ACM,da Silva FS,de Sousa MBC

更新日期：2017-09-21 00:00:00

abstract：:Mental imagery, seeing with the mind's eyes, can induce stronger positive as well as negative affect compared to verbal processing. Given this emotion-amplifying effect, it appears likely that mental images play an important role in affective disorders. According to the subcomponents model of depression, depressed moo...

journal_title：Frontiers in psychiatry

authors： Görgen SM,Joormann J,Hiller W,Witthöft M

更新日期：2015-07-07 00:00:00

abstract：:Background: Inpatient mental health wards are reported by many consumers to be custodial, unsafe, and lacking in therapeutic relationships. These consumer experiences are concerning, given international policy directives requiring recovery-oriented practice. Safewards is both a model and a suite of interventions desig...

journal_title：Frontiers in psychiatry

authors： Fletcher J,Buchanan-Hagen S,Brophy L,Kinner SA,Hamilton B

更新日期：2019-07-09 00:00:00

abstract：:Over the past years, there has been a growing interest in the association between lifestyle psychosocial interventions, severe mental illness, and suicide risk. Patients with severe mental disorders have higher mortality rates, poor health states, and higher suicide risk compared to the general population. Lifestyle b...

journal_title：Frontiers in psychiatry

authors： Berardelli I,Corigliano V,Hawkins M,Comparelli A,Erbuto D,Pompili M

更新日期：2018-11-06 00:00:00

abstract：Objective:To explore the attitudes and factors in seeking professional psychological help among a Chinese community-dwelling population in order to promote positive help-seeking behaviors and better utilization of mental health services. Methods:Using system and simple random sampling with Kish selection table methods...

journal_title：Frontiers in psychiatry

authors： Chen P,Liu XJ,Wang XQ,Yang BX,Ruan J,Liu Z

更新日期：2020-05-14 00:00:00

abstract：:Objective: This study aims to understand the impact of negative life experience (NLE) in auditory hallucinations (AHs) and explain the heterogeneity in phenomenology of auditory verbal hallucinations (AVHs). Method: In depth interviews were conducted with 21 individuals (7 males and 14 females) experiencing AHs and ac...

journal_title：Frontiers in psychiatry

authors： Vallath S,Luhrmann T,Bunders J,Ravikant L,Gopikumar V

更新日期：2018-10-30 00:00:00

abstract：:Generalized anxiety disorder (GAD) is a common but serious form of anxiety disorder. Despite this, the rate of GAD recognition in primary care remains low in both Western and Eastern countries. The GAD-7 and GAD-2 were developed to efficiently identify people with GAD, and their reliability and validity have been well...

journal_title：Frontiers in psychiatry

authors： Ahn JK,Kim Y,Choi KH

更新日期：2019-03-18 00:00:00

abstract：:Impaired manual dexterity is commonly observed in schizophrenia. However, a quantitative description of key sensorimotor components contributing to impaired dexterity is lacking. Whether the key components of dexterity are differentially affected and how they relate to clinical characteristics also remains unclear. We...

journal_title：Frontiers in psychiatry

authors： Térémetz M,Carment L,Brénugat-Herne L,Croca M,Bleton JP,Krebs MO,Maier MA,Amado I,Lindberg PG

更新日期：2017-07-10 00:00:00

abstract：:Increasing evidence suggests that binge eating-related disorders could be related to addiction-like eating patterns due to the addictive potential of hyperpalatable foods. Subsequently, important implications have been derived for treatment of those disorders and even political actions. However, studies on the prevale...

journal_title：Frontiers in psychiatry

authors： Meule A

更新日期：2011-11-03 00:00:00

abstract：:Objective: The ACCESS treatment model offers assertive community treatment (ACT) embedded in an integrated care program to patients with severe psychotic disorders. Compared to standard care, it proved to be more effective in terms of service disengagement and other outcomes in patients with psychotic disorders over 1...

journal_title：Frontiers in psychiatry

authors： Schöttle D,Ruppelt F,Schimmelmann BG,Karow A,Bussopulos A,Gallinat J,Wiedemann K,Luedecke D,Rohenkohl AC,Huber CG,Bock T,Lambert M

更新日期：2019-10-24 00:00:00

abstract：:Characteristics unique to forensic psychiatric treatment include coming to terms with the offenses committed, the long duration of treatment and the assessment of the risk of repeat offending. This study describes the views of both patients and staff on the significance of the patient's offense as a part of forensic p...

journal_title：Frontiers in psychiatry

authors： Askola R,Soininen P,Seppänen A

更新日期：2020-01-08 00:00:00

abstract：:Major depression is a high-prevalence mental disease with major socio-economic impact, for both the direct and the indirect costs. Major depression symptoms can be faked or exaggerated in order to obtain economic compensation from insurance companies. Critically, depression is potentially easily malingered, as the sym...

journal_title：Frontiers in psychiatry

authors： Monaro M,Toncini A,Ferracuti S,Tessari G,Vaccaro MG,De Fazio P,Pigato G,Meneghel T,Scarpazza C,Sartori G

更新日期：2018-06-08 00:00:00

abstract：Background:High prevalence of mental disorders has been found among female prisoners in Western countries, however, little is known about the epidemiology of mental disorders in such populations in China. This study aims to investigate psychiatric morbidity and comorbidity among sentenced prisoners in a female prison i...

journal_title：Frontiers in psychiatry

authors： Zhong S,Zhu X,Chen Y,Guo H,Luo C,Liang X,Wang F,Chen H,Zhou J,Wang X

更新日期：2020-04-14 00:00:00

abstract：Objective:Suicide is one of the main reasons cited behind the death rate of cancer, and suicidal ideation (SI) is the first step toward it. This study aimed to investigate the prevalence and associates of suicidal ideation in newly-diagnosed Chinese cancer patients. Methods:This multicenter study was conducted from Ja...

journal_title：Frontiers in psychiatry

authors： Zhang Y,Li W,Zhang Z,Sun H,Garg S,Yang Y,Wang H

更新日期：2020-07-23 00:00:00

abstract：:Task-based connectivity studies facilitate the understanding of how the brain functions during cognition, which is commonly impaired in schizophrenia (SZ). Our aim was to investigate functional connectivity during a working memory task in SZ. We hypothesized that the task-negative (default mode) network and the cognit...

journal_title：Frontiers in psychiatry

authors： Godwin D,Ji A,Kandala S,Mamah D

更新日期：2017-12-22 00:00:00

abstract：:Background: A large portion of previous studies that have demonstrated brain gray matter reduction in individuals who use methamphetamine (MA) have focused on short-term abstinence, but few studies have focused on the effects of long-term abstinence of methamphetamine on brain structures. Materials and Methods: Our st...

journal_title：Frontiers in psychiatry

authors： Zhang Z,He L,Huang S,Fan L,Li Y,Li P,Zhang J,Liu J,Yang R

更新日期：2018-12-20 00:00:00

abstract：:The treatment of heroin addiction is a complex process involving changes in addictive behavior and brain functioning. The goal of this study was to explore the brain default mode network (DMN) functional connectivity using resting-state functional magnetic resonance imaging (rs-fMRI) and decision-making performance ba...

journal_title：Frontiers in psychiatry

authors： Kuo LW,Lin PS,Lin SY,Liu MF,Jan H,Lee HC,Wang SC

更新日期：2019-06-06 00:00:00

abstract：:Autobiographical memory (AM) impairment in schizophrenia affects the richness of detail in personal memories and is one of the major predictors of patients' social functioning. Despite the empirical evidence attributing these difficulties to a defective encoding process, cognitive remediation interventions targeting A...

journal_title：Frontiers in psychiatry

authors： Dassing R,Allé MC,Cerbai M,Obrecht A,Meyer N,Vidailhet P,Danion JM,Mengin AC,Berna F

更新日期：2020-05-08 00:00:00

abstract：:Introduction: Previous studies on internet gaming disorder (IGD) have reported an association between personality traits and impulsive or problematic use of the internet or internet games, but the results obtained were inconsistent. Our study's hypothesis was that personality traits are associated with the individual'...

journal_title：Frontiers in psychiatry

authors： Seong W,Hong JS,Kim S,Kim SM,Han DH

更新日期：2019-08-28 00:00:00

abstract：:Pharmacogenomics represents a potentially powerful enhancement to the current standard of care for psychiatric patients. However, a variety of biological and technical challenges must be addressed in order to provide adequate clinical decision support for personalized prescribing and dosing based on genomic data. This...

journal_title：Frontiers in psychiatry

authors： Jarvis JP,Peter AP,Shaman JA

更新日期：2019-06-20 00:00:00

abstract：:Although there is general consensus that altered brain structure and function underpins addictive disorders, clinicians working in addiction treatment rarely incorporate neuroscience-informed approaches into their practice. We recently launched the Neuroscience Interest Group within the International Society of Addict...

journal_title：Frontiers in psychiatry

authors： Verdejo-Garcia A,Lorenzetti V,Manning V,Piercy H,Bruno R,Hester R,Pennington D,Tolomeo S,Arunogiri S,Bates ME,Bowden-Jones H,Campanella S,Daughters SB,Kouimtsidis C,Lubman DI,Meyerhoff DJ,Ralph A,Rezapour T,Tavakoli H

更新日期：2019-12-23 00:00:00

abstract：BACKGROUND:Research has demonstrated a reduction in olfactory functioning in patients with schizophrenia. This research has led to examination of olfactory functioning in other mental disorders, such as depression. There is a great deal of variation in the results generated from such research, and it remains unclear as...

journal_title：Frontiers in psychiatry

authors： Taalman H,Wallace C,Milev R

更新日期：2017-09-28 00:00:00