Milk From Cow Fed With High Forage/Concentrate Ratio Diet: Beneficial Effect on Rat Skeletal Muscle Inflammatory State and Oxidative Stress Through Modulation of Mitochondrial Functions and AMPK Activity.

Abstract:

:Milk and dairy products are relevant components of daily diet and are part of dietary recommendation in many countries due to their content of key nutrients. However, the relatively high content of saturated fat of the milk and its extensive usage for every age group raises concerns about its potential negative health effects. Therefore, in the last years, several researchers dedicated their attention to milk production and quality. Milk fatty acids profile depend on cow feeding and in particular on the type of forage and concentrate and forage/concentrate ratio. It was demonstrated that feeding dairy cows with a 70/30 forage/concentrate ratio yields milk with a low ω6:ω3 ratio and high CLA levels. In this work, we demonstrated that the supplementation of rats diet with this high forage milk (HFM) results, in the skeletal muscle of these animals, in a reduced lipid content and inflammation levels, and an improved mitochondrial lipid oxidation, and redox status through modulation of AMPK activity.

journal_name

Front Physiol

journal_title

Frontiers in physiology

authors

Trinchese G,Cavaliere G,Penna E,De Filippo C,Cimmino F,Catapano A,Musco N,Tudisco R,Lombardi P,Infascelli F,Messina G,Muredda L,Banni S,Monda M,Crispino M,Mollica MP

doi

10.3389/fphys.2018.01969

subject

Has Abstract

pub_date

2019-01-17 00:00:00

pages

1969

issn

1664-042X

journal_volume

9

pub_type

杂志文章
  • Altered Right Ventricular Mechanical Properties Are Afterload Dependent in a Rodent Model of Bronchopulmonary Dysplasia.

    abstract::Infants born premature are at increased risk for development of bronchopulmonary dysplasia (BPD), pulmonary hypertension (PH), and ultimately right ventricular (RV) dysfunction, which together carry a high risk of neonatal mortality. However, the role alveolar simplification and abnormal pulmonary microvascular develo...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章

    doi:10.3389/fphys.2017.00840

    authors: Patel JR,Barton GP,Braun RK,Goss KN,Haraldsdottir K,Hopp A,Diffee G,Hacker TA,Moss RL,Eldridge MW

    更新日期:2017-10-25 00:00:00

  • On the Role of the Head Ganglia in Posture and Walking in Insects.

    abstract::In insects, locomotion is the result of rhythm generating thoracic circuits and their modulation by sensory reflexes and by inputs from the two head ganglia, the cerebral and the gnathal ganglia (GNG), which act as higher order neuronal centers playing different functions in the initiation, goal-direction, and mainten...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章,评审

    doi:10.3389/fphys.2020.00135

    authors: Emanuel S,Kaiser M,Pflueger HJ,Libersat F

    更新日期:2020-02-21 00:00:00

  • The Circadian Clock Improves Fitness in the Fruit Fly, Drosophila melanogaster.

    abstract::It is assumed that a properly timed circadian clock enhances fitness, but only few studies have truly demonstrated this in animals. We raised each of the three classical Drosophila period mutants for >50 generations in the laboratory in competition with wildtype flies. The populations were either kept under a conventi...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章

    doi:10.3389/fphys.2019.01374

    authors: Horn M,Mitesser O,Hovestadt T,Yoshii T,Rieger D,Helfrich-Förster C

    更新日期:2019-11-01 00:00:00

  • Inhibition of miR-27b Regulates Lipid Metabolism in Skeletal Muscle of Obese Rats During Hypoxic Exercise by Increasing PPARγ Expression.

    abstract::Hypoxic exercise may represent a novel therapeutic strategy to reduce and prevent obesity through the regulation of lipid metabolism. During hypoxic exercise, the targeting of peroxisome proliferator-activated receptor gamma (PPARγ) by miR-27b has been proposed to be one of the mechanisms involved in the modulation of...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章

    doi:10.3389/fphys.2020.01090

    authors: Wang X,Lu Y,Zhu L,Zhang H,Feng L

    更新日期:2020-08-31 00:00:00

  • Heat Shock Factor Is Involved in Regulating the Transcriptional Expression of Two Potential Hsps (AhHsp70 and AhsHsp21) and Its Role in Heat Shock Response of Agasicles hygrophila.

    abstract::Heat shock proteins are molecular chaperones that are involved in numerous normal cellular processes and stress responses, and heat shock factors are transcriptional activators of heat shock proteins. Heat shock factors and heat shock proteins are coordinated in various biological processes. The regulatory function of...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章

    doi:10.3389/fphys.2020.562204

    authors: Jin J,Li Y,Zhou Z,Zhang H,Guo J,Wan F

    更新日期:2020-09-15 00:00:00

  • Dynamical Boolean Modeling of Immunogenic Cell Death.

    abstract::As opposed to the standard tolerogenic apoptosis, immunogenic cell death (ICD) constitutes a type of cellular demise that elicits an adaptive immune response. ICD has been characterized in malignant cells following cytotoxic interventions, such as chemotherapy or radiotherapy. Briefly, ICD of cancer cells releases som...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章

    doi:10.3389/fphys.2020.590479

    authors: Checcoli A,Pol JG,Naldi A,Noel V,Barillot E,Kroemer G,Thieffry D,Calzone L,Stoll G

    更新日期:2020-11-12 00:00:00

  • Investigating the Combinatory Effects of Biological Networks on Gene Co-expression.

    abstract::Co-expressed genes often share similar functions, and gene co-expression networks have been widely used in studying the functionality of gene modules. Previous analysis indicated that genes are more likely to be co-expressed if they are either regulated by the same transcription factors, forming protein complexes or s...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章

    doi:10.3389/fphys.2016.00160

    authors: Zhang C,Lee S,Mardinoglu A,Hua Q

    更新日期:2016-05-02 00:00:00

  • High Altitude Affects Nocturnal Non-linear Heart Rate Variability: PATCH-HA Study.

    abstract::Background: High altitude (HA) exposure can lead to changes in resting heart rate variability (HRV), which may be linked to acute mountain sickness (AMS) development. Compared with traditional HRV measures, non-linear HRV appears to offer incremental and prognostic data, yet its utility and relationship to AMS have be...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章

    doi:10.3389/fphys.2018.00390

    authors: Boos CJ,Bye K,Sevier L,Bakker-Dyos J,Woods DR,Sullivan M,Quinlan T,Mellor A

    更新日期:2018-04-16 00:00:00

  • The multiple roles of fatty acid handling proteins in brain.

    abstract::Lipids are essential components of a living organism as energy source but also as constituent of the membrane lipid bilayer. In addition fatty acid (FA) derivatives interact with many signaling pathways. FAs have amphipathic properties and therefore require being associated to protein for both transport and intracellu...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章

    doi:10.3389/fphys.2012.00385

    authors: Moullé VS,Cansell C,Luquet S,Cruciani-Guglielmacci C

    更新日期:2012-09-28 00:00:00

  • Cellular cardiac electrophysiology modeling with Chaste and CellML.

    abstract::Chaste is an open-source C++ library for computational biology that has well-developed cardiac electrophysiology tissue simulation support. In this paper, we introduce the features available for performing cardiac electrophysiology action potential simulations using a wide range of models from the Physiome repository....

    journal_title:Frontiers in physiology

    pub_type: 杂志文章

    doi:10.3389/fphys.2014.00511

    authors: Cooper J,Spiteri RJ,Mirams GR

    更新日期:2015-01-06 00:00:00

  • Distinguishing Epileptiform Discharges From Normal Electroencephalograms Using Adaptive Fractal and Network Analysis: A Clinical Perspective.

    abstract::Epilepsy is one of the most common disorders of the brain. Clinically, to corroborate an epileptic seizure-like symptom and to find the seizure localization, electroencephalogram (EEG) data are often visually examined by a clinical doctor to detect the presence of epileptiform discharges. Epileptiform discharges are t...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章

    doi:10.3389/fphys.2020.00828

    authors: Li Q,Gao J,Zhang Z,Huang Q,Wu Y,Xu B

    更新日期:2020-08-05 00:00:00

  • Crayfish Self-Administer Amphetamine in a Spatially Contingent Task.

    abstract::Natural reward is an essential element of any organism's ability to adapt to environmental variation. Its underlying circuits and mechanisms guide the learning process as they help associate an event, or cue, with the perception of an outcome's value. More generally, natural reward serves as the fundamental generator ...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章

    doi:10.3389/fphys.2018.00433

    authors: Datta U,van Staaden M,Huber R

    更新日期:2018-05-14 00:00:00

  • Stiffness of the Gastrocnemius-Achilles Tendon Complex Between Amateur Basketball Players and the Non-athletic General Population.

    abstract::Muscle and tendon stiffness are related to sports performance, tendinopathy, and tendon degeneration. However, the effects of habitual loading on muscle and tendon mechanical properties are unclear. Using amateur basketball players as examples, we investigated the effects of mechanical loading on the stiffness of the ...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章

    doi:10.3389/fphys.2020.606706

    authors: Chang TT,Li Z,Wang XQ,Zhang ZJ

    更新日期:2020-12-10 00:00:00

  • Acute Response of Circulating Vascular Regulating MicroRNAs during and after High-Intensity and High-Volume Cycling in Children.

    abstract:AIM:The aim of the present study was to analyze the response of vascular circulating microRNAs (miRNAs; miR-16, miR-21, miR-126) and the VEGF mRNA following an acute bout of HIIT and HVT in children. METHODS:Twelve healthy competitive young male cyclists (14.4 ± 0.8 years; 57.9 ± 9.4 ml·min(-1)·kg(-1) peak oxygen upta...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章

    doi:10.3389/fphys.2016.00092

    authors: Kilian Y,Wehmeier UF,Wahl P,Mester J,Hilberg T,Sperlich B

    更新日期:2016-03-14 00:00:00

  • Identification of Wolbachia-Responsive miRNAs in the Small Brown Planthopper, Laodelphax striatellus.

    abstract::Laodelphax striatellus is naturally infected with the Wolbachia strain wStri, which induces strong cytoplasmic incompatibility of its host. MicroRNAs (miRNAs) are a class of endogenous non-coding small RNAs that play a critical role in the regulation of gene expression at post-transcriptional level in various biologic...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章

    doi:10.3389/fphys.2019.00928

    authors: Liu L,Zhang KJ,Rong X,Li YY,Liu H

    更新日期:2019-07-24 00:00:00

  • Increases in apoptosis, caspase activity and expression of p53 and bax, and the transition between two types of mitochondrion-rich cells, in the gills of the climbing perch, Anabas testudineus, during a progressive acclimation from freshwater to seawater.

    abstract::This study aimed to test the hypothesis that branchial osmoregulatory acclimation involved increased apoptosis and replacement of mitochdonrion-rich cells (MRCs) in the climbing perch, Anabas testudineus, during a progressive acclimation from freshwater to seawater. A significant increase in branchial caspase-3/-7 act...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章

    doi:10.3389/fphys.2013.00135

    authors: Ching B,Chen XL,Yong JH,Wilson JM,Hiong KC,Sim EW,Wong WP,Lam SH,Chew SF,Ip YK

    更新日期:2013-06-07 00:00:00

  • Effects of Resistance Exercise and Nutritional Supplementation on Dynamic Cerebral Autoregulation in Head-Down Bed Rest.

    abstract::Head-down bed rest (HDBR) is commonly considered as ground-based analog to spaceflight and simulates the headward fluid shift and cardiovascular deconditioning associated with spaceflight. We investigated in healthy volunteers whether HDBR, with or without countermeasures, affect cerebral autoregulation (CA). Twelve m...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章

    doi:10.3389/fphys.2019.01114

    authors: Kermorgant M,Nasr N,Custaud MA,Navasiolava N,Arbeille P,Guinet P,Labrunée M,Besnier F,Arvanitis DN,Czosnyka M,Senard JM,Pavy-Le Traon A

    更新日期:2019-08-27 00:00:00

  • Xenbase: Facilitating the Use of Xenopus to Model Human Disease.

    abstract::At a fundamental level most genes, signaling pathways, biological functions and organ systems are highly conserved between man and all vertebrate species. Leveraging this conservation, researchers are increasingly using the experimental advantages of the amphibian Xenopus to model human disease. The online Xenopus res...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章,评审

    doi:10.3389/fphys.2019.00154

    authors: Nenni MJ,Fisher ME,James-Zorn C,Pells TJ,Ponferrada V,Chu S,Fortriede JD,Burns KA,Wang Y,Lotay VS,Wang DZ,Segerdell E,Chaturvedi P,Karimi K,Vize PD,Zorn AM

    更新日期:2019-02-26 00:00:00

  • Mechanosensitive Molecular Networks Involved in Transducing Resistance Exercise-Signals into Muscle Protein Accretion.

    abstract::Loss of skeletal muscle myofibrillar protein with disease and/or inactivity can severely deteriorate muscle strength and function. Strategies to counteract wasting of muscle myofibrillar protein are therefore desirable and invite for considerations on the potential superiority of specific modes of resistance exercise ...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章,评审

    doi:10.3389/fphys.2016.00547

    authors: Rindom E,Vissing K

    更新日期:2016-11-17 00:00:00

  • Dysfunctional LAT2 Amino Acid Transporter Is Associated With Cataract in Mouse and Humans.

    abstract::Cataract, the loss of ocular lens transparency, accounts for ∼50% of worldwide blindness and has been associated with water and solute transport dysfunction across lens cellular barriers. We show that neutral amino acid antiporter LAT2 (Slc7a8) and uniporter TAT1 (Slc16a10) are expressed on mouse ciliary epithelium an...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章

    doi:10.3389/fphys.2019.00688

    authors: Knöpfel EB,Vilches C,Camargo SMR,Errasti-Murugarren E,Stäubli A,Mayayo C,Munier FL,Miroshnikova N,Poncet N,Junza A,Bhattacharya SS,Prat E,Berry V,Berger W,Heon E,Moore AT,Yanes Ó,Nunes V,Palacín M,Verrey F,Kloecke

    更新日期:2019-06-04 00:00:00

  • Posttranslational Amelogenin Processing and Changes in Matrix Assembly during Enamel Development.

    abstract::The extracellular tooth enamel matrix is a unique, protein-rich environment that provides the structural basis for the growth of long and parallel oriented enamel crystals. Here we have conducted a series of in vivo and in vitro studies to characterize the changes in matrix shape and organization that take place durin...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章

    doi:10.3389/fphys.2017.00790

    authors: Pandya M,Lin T,Li L,Allen MJ,Jin T,Luan X,Diekwisch TGH

    更新日期:2017-10-17 00:00:00

  • Down-regulation of pancreatic and duodenal homeobox-1 by somatostatin receptor subtype 5: a novel mechanism for inhibition of cellular proliferation and insulin secretion by somatostatin.

    abstract::Somatostatin (SST) is a regulatory peptide and acts as an endogenous inhibitory regulator of the secretory and proliferative responses of target cells. SST's actions are mediated by a family of seven transmembrane domain G protein-coupled receptors that comprise five distinct subtypes (SSTR1-5). SSTR5 is one of the ma...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章,评审

    doi:10.3389/fphys.2014.00226

    authors: Zhou G,Sinnett-Smith J,Liu SH,Yu J,Wu J,Sanchez R,Pandol SJ,Abrol R,Nemunaitis J,Rozengurt E,Brunicardi FC

    更新日期:2014-06-25 00:00:00

  • Scalable and Accurate ECG Simulation for Reaction-Diffusion Models of the Human Heart.

    abstract::Realistic electrocardiogram (ECG) simulation with numerical models is important for research linking cellular and molecular physiology to clinically observable signals, and crucial for patient tailoring of numerical heart models. However, ECG simulation with a realistic torso model is computationally much harder than ...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章

    doi:10.3389/fphys.2018.00370

    authors: Potse M

    更新日期:2018-04-20 00:00:00

  • Perindopril and a Galectin-3 Inhibitor Improve Ischemic Heart Failure in Rabbits by Reducing Gal-3 Expression and Myocardial Fibrosis.

    abstract::Objective: Ventricular remodeling is considered the basis of heart failure and is involved in myocardial fibrosis. This study aimed to assess perindopril and a galectin-3 inhibitor (modified citrus pectin, MCP) for their effects on ventricular remodeling and myocardial fibrosis in rabbits with ischemic heart failure. ...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章

    doi:10.3389/fphys.2019.00267

    authors: Li S,Li S,Hao X,Zhang Y,Deng W

    更新日期:2019-03-22 00:00:00

  • Oral Administration of Penicillin or Streptomycin May Alter Serum Serotonin Level and Intestinal Motility via Different Mechanisms.

    abstract:Background/Aims:Enterochromaffin cells (EC cells) constitute the largest population of enteroendocrine cells and release serotonin (5-HT) in response to mechanical and chemical cues of the gastrointestinal tract (GIT). How EC cells respond to altered microbiota such as due to antibiotic treatments remain poorly underst...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章

    doi:10.3389/fphys.2020.605982

    authors: Zhu C,Gong H,Luo P,Dong L,Zhang G,Shi X,Rong W

    更新日期:2020-12-23 00:00:00

  • AltitudeOmics: Spontaneous Baroreflex Sensitivity During Acclimatization to 5,260 m: A Comparison of Methods.

    abstract:Introduction:Baroreflex sensitivity (BRS) is essential to ensure rapid adjustment to variations in blood pressure (BP). Spontaneous baroreflex function can be assessed using continuous recordings of blood pressure. The goal of this study was to compare four methods for BRS quantification [the sequence, Bernardi's (BER)...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章

    doi:10.3389/fphys.2019.01505

    authors: Bourdillon N,Yazdani S,Vesin JM,Subudhi AW,Lovering AT,Roach RC,Kayser B

    更新日期:2019-12-10 00:00:00

  • Adenosine: Direct and Indirect Actions on Gastric Acid Secretion.

    abstract::Composed by a molecule of adenine and a molecule of ribose, adenosine is a paradigm of recyclable nucleoside with a multiplicity of functions that occupies a privileged position in the metabolic and regulatory contexts. Adenosine is formed continuously in intracellular and extracellular locations of all tissues. Extra...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章,评审

    doi:10.3389/fphys.2017.00737

    authors: Arin RM,Gorostidi A,Navarro-Imaz H,Rueda Y,Fresnedo O,Ochoa B

    更新日期:2017-09-22 00:00:00

  • Glutamate Cysteine Ligase-Modulatory Subunit Knockout Mouse Shows Normal Insulin Sensitivity but Reduced Liver Glycogen Storage.

    abstract::Glutathione (GSH) deficits have been observed in several mental or degenerative illness, and so has the metabolic syndrome. The impact of a decreased glucose metabolism on the GSH system is well-known, but the effect of decreased GSH levels on the energy metabolism is unclear. The aim of the present study was to inves...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章

    doi:10.3389/fphys.2016.00142

    authors: Lavoie S,Steullet P,Kulak A,Preitner F,Do KQ,Magistretti PJ

    更新日期:2016-04-21 00:00:00

  • Pinocembrin Protects Against Dextran Sulfate Sodium-Induced Rats Colitis by Ameliorating Inflammation, Improving Barrier Function and Modulating Gut Microbiota.

    abstract::Pinocembrin (PIN) is a natural flavonoid widely found in bee propolis with potent gastrointestinal protective effects. In consequence, PIN has great potential in preventing inflammatory bowel diseases (IBDs) while scant information is available. In this study, a dextran sulfate sodium (DSS)-induced rats ulcerative col...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章

    doi:10.3389/fphys.2019.00908

    authors: Hu L,Wu C,Zhang Z,Liu M,Maruthi Prasad E,Chen Y,Wang K

    更新日期:2019-07-19 00:00:00

  • Hippo Pathway and Skeletal Muscle Mass Regulation in Mammals: A Controversial Relationship.

    abstract::Skeletal muscle mass reflects a dynamic turnover between net protein synthesis and degradation. In addition, satellite cell inclusion may contribute to increase muscle mass while fiber loss results in a reduction of muscle mass. Since 2010, a few studies looked at the involvement of the newly discovered Hippo pathway ...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章,评审

    doi:10.3389/fphys.2017.00190

    authors: Gnimassou O,Francaux M,Deldicque L

    更新日期:2017-03-29 00:00:00