Electroencephalography-based endogenous brain-computer interface for online communication with a completely locked-in patient.


BACKGROUND:Brain-computer interfaces (BCIs) have demonstrated the potential to provide paralyzed individuals with new means of communication, but an electroencephalography (EEG)-based endogenous BCI has never been successfully used for communication with a patient in a completely locked-in state (CLIS). METHODS:In this study, we investigated the possibility of using an EEG-based endogenous BCI paradigm for online binary communication by a patient in CLIS. A female patient in CLIS participated in this study. She had not communicated even with her family for more than one year with complete loss of motor function. Offline and online experiments were conducted to validate the feasibility of the proposed BCI system. In the offline experiment, we determined the best combination of mental tasks and the optimal classification strategy leading to the best performance. In the online experiment, we investigated whether our BCI system could be potentially used for real-time communication with the patient. RESULTS:An online classification accuracy of 87.5% was achieved when Riemannian geometry-based classification was applied to real-time EEG data recorded while the patient was performing one of two mental-imagery tasks for 5 s. CONCLUSIONS:Our results suggest that an EEG-based endogenous BCI has the potential to be used for online communication with a patient in CLIS.


J Neuroeng Rehabil


Han CH,Kim YW,Kim DY,Kim SH,Nenadic Z,Im CH




Has Abstract


2019-01-30 00:00:00












  • Evaluation of the effects of the Arm Light Exoskeleton on movement execution and muscle activities: a pilot study on healthy subjects.

    abstract:BACKGROUND:Exoskeletons for lower and upper extremities have been introduced in neurorehabilitation because they can guide the patient's limb following its anatomy, covering many degrees of freedom and most of its natural workspace, and allowing the control of the articular joints. The aims of this study were to evalua...

    journal_title:Journal of neuroengineering and rehabilitation

    pub_type: 杂志文章


    authors: Pirondini E,Coscia M,Marcheschi S,Roas G,Salsedo F,Frisoli A,Bergamasco M,Micera S

    更新日期:2016-01-23 00:00:00

  • Using non-invasive brain stimulation to augment motor training-induced plasticity.

    abstract::Therapies for motor recovery after stroke or traumatic brain injury are still not satisfactory. To date the best approach seems to be the intensive physical therapy. However the results are limited and functional gains are often minimal. The goal of motor training is to minimize functional disability and optimize func...

    journal_title:Journal of neuroengineering and rehabilitation

    pub_type: 杂志文章,评审


    authors: Bolognini N,Pascual-Leone A,Fregni F

    更新日期:2009-03-17 00:00:00

  • True functional ability of chronic stroke patients.

    abstract:BACKGROUND:There is a paucity of information regarding visuospatial (VS) and visuomotor (VM) task performance in patients with chronic right fronto-parietal lobe stroke, as the majority of knowledge to date in this realm has been gleaned from acute stroke patients. The goal of this paper is to determine how VS and VM p...

    journal_title:Journal of neuroengineering and rehabilitation

    pub_type: 杂志文章


    authors: Tippett WJ,Alexander LD,Rizkalla MN,Sergio LE,Black SE

    更新日期:2013-02-13 00:00:00

  • Upper limb impairments associated with spasticity in neurological disorders.

    abstract:BACKGROUND:While upper-extremity movement in individuals with neurological disorders such as stroke and spinal cord injury (SCI) has been studied for many years, the effects of spasticity on arm movement have been poorly quantified. The present study is designed to characterize the nature of impaired arm movements asso...

    journal_title:Journal of neuroengineering and rehabilitation

    pub_type: 杂志文章


    authors: Tsao CC,Mirbagheri MM

    更新日期:2007-11-29 00:00:00

  • Automatic identification of gait events using an instrumented sock.

    abstract:BACKGROUND:Textile-based transducers are an emerging technology in which piezo-resistive properties of materials are used to measure an applied strain. By incorporating these sensors into a sock, this technology offers the potential to detect critical events during the stance phase of the gait cycle. This could prove u...

    journal_title:Journal of neuroengineering and rehabilitation

    pub_type: 杂志文章


    authors: Preece SJ,Kenney LP,Major MJ,Dias T,Lay E,Fernandes BT

    更新日期:2011-05-27 00:00:00

  • Dual-task training of children with neuromotor disorders during robot-assisted gait therapy: prerequisites of patients and influence on leg muscle activity.

    abstract:BACKGROUND:Walking in daily life is complex entailing various prerequisites such as leg strength, trunk stability or cognitive and motor dual task (DT) activities. Conventional physiotherapy can be complemented with robot-assisted gait therapy (RAGT) and exergames to enhance the number of step repetitions, feedback, mo...

    journal_title:Journal of neuroengineering and rehabilitation

    pub_type: 临床试验,杂志文章


    authors: Ricklin S,Meyer-Heim A,van Hedel HJA

    更新日期:2018-09-17 00:00:00

  • Cortical activation change induced by neuromuscular electrical stimulation during hand movements: a functional NIRS study.

    abstract:OBJECTIVES:Neuromuscular electrical stimulation (NMES) has been used in the field of rehabilitation for a long time. Previous studies on NMES have focused on the peripheral effect, in contrast, relatively little is known about the effect on the cerebral cortex. In the current study, we attempted to investigate the chan...

    journal_title:Journal of neuroengineering and rehabilitation

    pub_type: 临床试验,杂志文章


    authors: Jang SH,Jang WH,Chang PH,Lee SH,Jin SH,Kim YG,Yeo SS

    更新日期:2014-03-05 00:00:00

  • A kinematic analysis of a haptic handheld stylus in a virtual environment: a study in healthy subjects.

    abstract:BACKGROUND:Virtual Reality provides new options for conducting motor assessment and training within computer-generated 3 dimensional environments. To date very little has been reported about normal performance in virtual environments. The objective of this study was to evaluate the test-retest reliability of a clinical...

    journal_title:Journal of neuroengineering and rehabilitation

    pub_type: 杂志文章


    authors: Broeren J,Sunnerhagen KS,Rydmark M

    更新日期:2007-05-09 00:00:00

  • Reduction of freezing of gait in Parkinson's disease by repetitive robot-assisted treadmill training: a pilot study.

    abstract:BACKGROUND:Parkinson's disease is a chronic, neurodegenerative disease characterized by gait abnormalities. Freezing of gait (FOG), an episodic inability to generate effective stepping, is reported as one of the most disabling and distressing parkinsonian symptoms. While there are no specific therapies to treat FOG, so...

    journal_title:Journal of neuroengineering and rehabilitation

    pub_type: 杂志文章


    authors: Lo AC,Chang VC,Gianfrancesco MA,Friedman JH,Patterson TS,Benedicto DF

    更新日期:2010-10-14 00:00:00

  • Ipsilateral EEG mu rhythm reflects the excitability of uncrossed pathways projecting to shoulder muscles.

    abstract:BACKGROUND:Motor planning, imagery or execution is associated with event-related desynchronization (ERD) of mu rhythm oscillations (8-13 Hz) recordable over sensorimotor areas using electroencephalography (EEG). It was shown that motor imagery involving distal muscles, e.g. finger movements, results in contralateral ER...

    journal_title:Journal of neuroengineering and rehabilitation

    pub_type: 杂志文章


    authors: Hasegawa K,Kasuga S,Takasaki K,Mizuno K,Liu M,Ushiba J

    更新日期:2017-08-25 00:00:00

  • Research highlights in neurorehabilitation.

    abstract::Recent studies of the mechanisms underlying plasticity and recovery following neurological injuries have originated innovative lines of research in neurorehabilitation. Additionally, the development of new technologies to facilitate the performance of evaluation and intervention procedures has stimulated research on n...

    journal_title:Journal of neuroengineering and rehabilitation

    pub_type: 社论


    authors: Pajaro-Blázquez M,Pons JL

    更新日期:2014-03-04 00:00:00

  • A task-specific interactive game-based virtual reality rehabilitation system for patients with stroke: a usability test and two clinical experiments.

    abstract:BACKGROUND:Virtual reality (VR) is not commonly used in clinical rehabilitation, and commercial VR gaming systems may have mixed effects in patients with stroke. Therefore, we developed RehabMaster™, a task-specific interactive game-based VR system for post-stroke rehabilitation of the upper extremities, and assessed i...

    journal_title:Journal of neuroengineering and rehabilitation

    pub_type: 杂志文章,随机对照试验


    authors: Shin JH,Ryu H,Jang SH

    更新日期:2014-03-06 00:00:00

  • Infrared thermography as an access pathway for individuals with severe motor impairments.

    abstract:BACKGROUND:People with severe motor impairments often require an alternative access pathway, such as a binary switch, to communicate and to interact with their environment. A wide range of access pathways have been developed from simple mechanical switches to sophisticated physiological ones. In this manuscript we repo...

    journal_title:Journal of neuroengineering and rehabilitation

    pub_type: 杂志文章


    authors: Memarian N,Venetsanopoulos AN,Chau T

    更新日期:2009-04-16 00:00:00

  • Control of cortical oscillatory frequency by a closed-loop system.

    abstract:BACKGROUND:We present a closed-loop system able to control the frequency of slow oscillations (SO) spontaneously generated by the cortical network in vitro. The frequency of SO can be controlled by direct current (DC) electric fields within a certain range. Here we set out to design a system that would be able to auton...

    journal_title:Journal of neuroengineering and rehabilitation

    pub_type: 杂志文章


    authors: D'Andola M,Giulioni M,Dante V,Del Giudice P,Sanchez-Vives MV

    更新日期:2019-01-09 00:00:00

  • Modular motor control of the sound limb in gait of people with trans-femoral amputation.

    abstract:BACKGROUND:The above-knee amputation of a lower limb is a severe impairment that affects significantly the ability to walk; considering this, a complex adaptation strategy at the neuromuscular level is needed in order to be able to move safely with a prosthetic knee. In literature, it has been demonstrated that muscle ...

    journal_title:Journal of neuroengineering and rehabilitation

    pub_type: 杂志文章


    authors: De Marchis C,Ranaldi S,Serrao M,Ranavolo A,Draicchio F,Lacquaniti F,Conforto S

    更新日期:2019-11-06 00:00:00

  • Brain-computer interfacing using modulations of alpha activity induced by covert shifts of attention.

    abstract:BACKGROUND:Visual brain-computer interfaces (BCIs) often yield high performance only when targets are fixated with the eyes. Furthermore, many paradigms use intense visual stimulation, which can be irritating especially in long BCI sessions. However, BCIs can more directly directly tap the neural processes underlying v...

    journal_title:Journal of neuroengineering and rehabilitation

    pub_type: 杂志文章


    authors: Treder MS,Bahramisharif A,Schmidt NM,van Gerven MA,Blankertz B

    更新日期:2011-05-05 00:00:00

  • Influence of body weight unloading on human gait characteristics: a systematic review.

    abstract:BACKGROUND:Body weight support (BWS) systems have shown promise as rehabilitation tools for neurologically impaired individuals. This paper reviews the experiment-based research on BWS systems with the aim: (1) To investigate the influence of body weight unloading (BWU) on gait characteristics; (2) To study whether the...

    journal_title:Journal of neuroengineering and rehabilitation

    pub_type: 杂志文章


    authors: Apte S,Plooij M,Vallery H

    更新日期:2018-06-20 00:00:00

  • Computer simulations of neural mechanisms explaining upper and lower limb excitatory neural coupling.

    abstract:BACKGROUND:When humans perform rhythmic upper and lower limb locomotor-like movements, there is an excitatory effect of upper limb exertion on lower limb muscle recruitment. To investigate potential neural mechanisms for this behavioral observation, we developed computer simulations modeling interlimb neural pathways a...

    journal_title:Journal of neuroengineering and rehabilitation

    pub_type: 杂志文章


    authors: Huang HJ,Ferris DP

    更新日期:2010-12-10 00:00:00

  • Leadership of the ultimate interdisciplinary team: Rehabilitation science at NIH.

    abstract:BACKGROUND:Support for rehabilitation research at the National Institutes of Health (NIH) is robust and evolving. Since the time of its Blue Ribbon Panel on Rehabilitation Research, NIH has participated in several initiatives to coordinate the science and advance the field. DISCUSSION:Collaborative teams must continue...

    journal_title:Journal of neuroengineering and rehabilitation

    pub_type: 信件


    authors: Cernich AN

    更新日期:2020-05-29 00:00:00

  • Controlling patient participation during robot-assisted gait training.

    abstract:BACKGROUND:The overall goal of this paper was to investigate approaches to controlling active participation in stroke patients during robot-assisted gait therapy. Although active physical participation during gait rehabilitation after stroke was shown to improve therapy outcome, some patients can behave passively durin...

    journal_title:Journal of neuroengineering and rehabilitation

    pub_type: 杂志文章


    authors: Koenig A,Omlin X,Bergmann J,Zimmerli L,Bolliger M,Müller F,Riener R

    更新日期:2011-03-23 00:00:00

  • Effect of vibration characteristics and vibror arrangement on the tactile perception of the upper arm in healthy subjects and upper limb amputees.

    abstract:BACKGROUND:Vibrotactile stimulation is a promising venue in the field of prosthetics to retrain sensory feedback deficits following amputation. Discrimination is well established at the forearm level but not at the upper arm level. Moreover, the effects of combining vibration characteristics such as duration and intens...

    journal_title:Journal of neuroengineering and rehabilitation

    pub_type: 杂志文章


    authors: Guemann M,Bouvier S,Halgand C,Paclet F,Borrini L,Ricard D,Lapeyre E,Cattaert D,Rugy A

    更新日期:2019-11-13 00:00:00

  • Muscle motor point identification is essential for optimizing neuromuscular electrical stimulation use.

    abstract::Transcutaneous neuromuscular electrical stimulation applied in clinical settings is currently characterized by a wide heterogeneity of stimulation protocols and modalities. Practitioners usually refer to anatomic charts (often provided with the user manuals of commercially available stimulators) for electrode position...

    journal_title:Journal of neuroengineering and rehabilitation

    pub_type: 社论


    authors: Gobbo M,Maffiuletti NA,Orizio C,Minetto MA

    更新日期:2014-02-25 00:00:00

  • The FreeD module for the Lokomat facilitates a physiological movement pattern in healthy people - a proof of concept study.

    abstract:BACKGROUND:A contralateral pelvic drop, a transverse rotation and a lateral translation of the pelvis are essential features of normal human gait. These motions are often restricted in robot-assisted gait devices. The optional FreeD module of the driven gait orthosis Lokomat (Hocoma AG, Switzerland) incorporates guided...

    journal_title:Journal of neuroengineering and rehabilitation

    pub_type: 杂志文章


    authors: Aurich-Schuler T,Gut A,Labruyère R

    更新日期:2019-02-06 00:00:00

  • Exercise self-efficacy and the relation with physical behavior and physical capacity in wheelchair-dependent persons with subacute spinal cord injury.

    abstract:BACKGROUND:Since physical activity and exercise levels are known to be generally low in persons with spinal cord injury (SCI), there seems to be a need for intervention. Exercise self-efficacy (ESE), the confidence persons have in their ability to be physically active and exercise, is an important and modifiable predic...

    journal_title:Journal of neuroengineering and rehabilitation

    pub_type: 杂志文章


    authors: Nooijen CF,Post MW,Spooren AL,Valent LJ,Broeksteeg R,Sluis TA,Stam HJ,Act-Active Research Group.,van den Berg-Emons RJ

    更新日期:2015-11-19 00:00:00

  • Intense and unpredictable perturbations during gait training improve dynamic balance abilities in chronic hemiparetic individuals: a randomized controlled pilot trial.

    abstract:BACKGROUND:Previous studies have assessed the effects of perturbation training on balance after stroke. However, the perturbations were either applied while standing or were small in amplitude during gait, which is not representative of the most common fall conditions. The perturbations were also combined with other ch...

    journal_title:Journal of neuroengineering and rehabilitation

    pub_type: 杂志文章,随机对照试验


    authors: Esmaeili V,Juneau A,Dyer JO,Lamontagne A,Kairy D,Bouyer L,Duclos C

    更新日期:2020-06-17 00:00:00

  • Co-contraction patterns of trans-tibial amputee ankle and knee musculature during gait.

    abstract:BACKGROUND:Myoelectric control of upper extremity powered prostheses has been used clinically for many years, however this approach has not been fully developed for lower extremity prosthetic devices. With the advent of powered lower extremity prosthetic components, the potential role of myoelectric control systems is ...

    journal_title:Journal of neuroengineering and rehabilitation

    pub_type: 杂志文章


    authors: Seyedali M,Czerniecki JM,Morgenroth DC,Hahn ME

    更新日期:2012-05-28 00:00:00

  • Home-based rehabilitation using a soft robotic hand glove device leads to improvement in hand function in people with chronic spinal cord injury:a pilot study.

    abstract:BACKGROUND:Loss of hand function following high level spinal cord injury (SCI) is perceived as a high priority area for rehabilitation. Following discharge, it is often impractical for the specialist care centre to provide ongoing therapy for people living with chronic SCI at home, which can lead to further deteriorati...

    journal_title:Journal of neuroengineering and rehabilitation

    pub_type: 临床试验,杂志文章


    authors: Osuagwu BAC,Timms S,Peachment R,Dowie S,Thrussell H,Cross S,Shirley R,Segura-Fragoso A,Taylor J

    更新日期:2020-03-05 00:00:00

  • Wearable kinesthetic system for capturing and classifying upper limb gesture in post-stroke rehabilitation.

    abstract::BACKGROUND: Monitoring body kinematics has fundamental relevance in several biological and technical disciplines. In particular the possibility to exactly know the posture may furnish a main aid in rehabilitation topics. In the present work an innovative and unobtrusive garment able to detect the posture and the movem...

    journal_title:Journal of neuroengineering and rehabilitation

    pub_type: 杂志文章


    authors: Tognetti A,Lorussi F,Bartalesi R,Quaglini S,Tesconi M,Zupone G,De Rossi D

    更新日期:2005-03-02 00:00:00

  • Visualizing the third dimension in virtual training environments for neurologically impaired persons: beneficial or disruptive?

    abstract:BACKGROUND:Many contemporary systems for neurorehabilitation utilize 3D virtual environments (VEs) that allow for training patients' hand or arm movements. In the current paper we comparatively test the effectiveness of two characteristics of VEs in rehabilitation training when utilizing a 3D haptic interaction device:...

    journal_title:Journal of neuroengineering and rehabilitation

    pub_type: 杂志文章


    authors: van den Hoogen W,Feys P,Lamers I,Coninx K,Notelaers S,Kerkhofs L,Ijsselsteijn W

    更新日期:2012-10-05 00:00:00

  • Adjusting kinematics and kinetics in a feedback-controlled toe walking model.

    abstract:BACKGROUND:In clinical gait assessment, the correct interpretation of gait kinematics and kinetics has a decisive impact on the success of the therapeutic programme. Due to the vast amount of information from which primary anomalies should be identified and separated from secondary compensatory changes, as well as the ...

    journal_title:Journal of neuroengineering and rehabilitation

    pub_type: 杂志文章


    authors: Olenšek A,Matjačić Z

    更新日期:2012-08-25 00:00:00