Changes in Blood microRNA Expression and Early Metabolic Responsiveness 21 Days Following Bariatric Surgery.

abstract：Background:Since hypothyroidism is a fairly common dysfunction, levothyroxine (L-T4) is one of the most prescribed medications. Approximately 70% of the administered L-T4 dose is absorbed. The absorption process takes place in the small intestine. Some disorders of the digestive system and some medicines, supplements, ...

journal_title：Frontiers in endocrinology

authors： Benvenga S,Capodicasa G,Perelli S,Ferrari SM,Fallahi P,Antonelli A

更新日期：2018-04-18 00:00:00

abstract：:Background and Objectives: Clitoromegaly is an important parameter in the evaluation of ambiguous genitalia in neonates, but the normative data for clitoral size in newborns have racial/ethnic differences. The present study aimed to determine clitoral length (CL) and clitoral width (CW) values and establish cutoff mea...

journal_title：Frontiers in endocrinology

authors： Alaei M,Rohani F,Norouzi E,Hematian Boroujeni N,Tafreshi RI,Salehiniya H,Soheilipour F

更新日期：2020-06-03 00:00:00

abstract：:Insulin-like growth factor-binding proteins (IGFBPs) are multifunctional proteins that possess IGF-dependent and -independent actions. Recent studies suggest that its IGF-independent action appeared early and that the IGF-binding function may have been acquired later in evolution. The timing of the emergence of IGF-de...

journal_title：Frontiers in endocrinology

authors： Zhong Y,Duan C

更新日期：2017-01-18 00:00:00

abstract：:Background: The relative contribution of reduced insulin sensitivity (Si) or insulin secretion to impaired fasting glucose (IFG) or diabetes mellitus (DM) has not been clarified in active acromegaly. An intravenous glucose tolerance test (IVGTT) was never used for the calculation of Si, acute insulin response (AIRg), ...

journal_title：Frontiers in endocrinology

authors： Niculescu DA,Dusceac R,Caragheorgheopol A,Popescu N,Poiana C

更新日期：2019-09-18 00:00:00

abstract：:Protease-activated receptors (PARs) belong to the G protein-coupled receptor (GPCR) family. Compared to other GPCRs, the specificity of the four PARs is the lack of physiologically soluble ligands able to induce their activation. Indeed, PARs are physiologically activated after proteolytic cleavage of their N-terminal...

journal_title：Frontiers in endocrinology

authors： Sébert M,Sola-Tapias N,Mas E,Barreau F,Ferrand A

更新日期：2019-10-24 00:00:00

abstract：:Previous work has shown that reduced expression of PLCXD3, a member of the phosphoinositide-specific phospholipases (PI-PLC) family, impaired insulin secretion with an unclear mechanism. In the current study, we aim to investigate the mechanism underlying this effect using human islets and rat INS-1 (832/13) cells. Mi...

journal_title：Frontiers in endocrinology

authors： Aljaibeji H,Mukhopadhyay D,Mohammed AK,Dhaiban S,Hachim MY,Elemam NM,Sulaiman N,Salehi A,Taneera J

更新日期：2019-11-06 00:00:00

abstract：:Background: Non-alcoholic fatty liver disease (NAFLD) is a well-known cause of liver dysfunction and has become a common chronic liver disease in many countries. However, the intrinsic molecular mechanisms underlying the pathogenesis of NAFLD have not yet been fully elucidated. Methods: We obtained the gene expression...

journal_title：Frontiers in endocrinology

authors： Jia X,Zhai T

更新日期：2019-08-30 00:00:00

abstract：:Diabetes is a worldwide public health concern as it is associated with various complications. One of the major complications of diabetes is diabetic foot syndrome that results in catastrophic events such as ulceration and amputation. Therefore, the main four strategies of diabetic foot care involve risk prediction, pr...

journal_title：Frontiers in endocrinology

authors： Balasubramanian G,Vas P,Chockalingam N,Naemi R

更新日期：2020-05-22 00:00:00

abstract：:Hypertrehalosemic hormone (HTH) is a peptide hormone that belongs to the adipokinetic hormone/red pigment concentrating hormone (AKH/RPCH) family, which exerts pleiotropic actions related to catabolic reaction and stress response. AKH peptides have been demonstrated to participate in stress response including oxidativ...

journal_title：Frontiers in endocrinology

authors： Huang JH,Bellés X,Lee HJ

更新日期：2012-01-09 00:00:00

abstract：:Gonadotropin-inhibitory hormone (GnIH) was first identified in Japanese quail to be an inhibitor of gonadotropin synthesis and release. GnIH peptides have since been identified in all vertebrates, and all share an LPXRFamide (X = L or Q) motif at their C-termini. The receptor for GnIH is the G protein-coupled receptor...

journal_title：Frontiers in endocrinology

authors： Ubuka T,Son YL,Tobari Y,Narihiro M,Bentley GE,Kriegsfeld LJ,Tsutsui K

更新日期：2014-01-27 00:00:00

abstract：:Background: Obesity and maternal age are the two most important factors independently affecting the risk of gestational diabetes mellitus (GDM). However, the age differences in the association between obesity and GDM remain unclear. The objectives of this cohort study included: (1) to determine the current incidence o...

journal_title：Frontiers in endocrinology

authors： Li G,Wei T,Ni W,Zhang A,Zhang J,Xing Y,Xing Q

更新日期：2020-09-11 00:00:00

abstract：:The insulin/IGF system plays an important role in cancer progression. Accordingly, elevated levels of circulating insulin have been associated with an increased cancer risk as well as with aggressive and metastatic cancer phenotypes. Numerous studies have documented that estrogens cooperate with the insulin/IGF system...

journal_title：Frontiers in endocrinology

authors： De Marco P,Cirillo F,Vivacqua A,Malaguarnera R,Belfiore A,Maggiolini M

更新日期：2015-03-06 00:00:00

abstract：:Gonadotropin-releasing hormone (GnRH) is the ultimate output signal of an intricate network of neuroendocrine factors that, acting on the pituitary, trigger gonadotropin release. In turn, gonadotropins exert their trophic action on the gonads to stimulate the synthesis of sex steroids thus completing the gonadotropic ...

journal_title：Frontiers in endocrinology

authors： Navarro VM

更新日期：2012-04-02 00:00:00

abstract：:The insulin signaling pathway is a modulator of metabolism in insects and can regulate functions associated with growth and development, as well as lipid and carbohydrate balance. We have previously reported the presence of an insulin-like peptide and an insulin-like growth factor in Rhodnius prolixus, which are invol...

journal_title：Frontiers in endocrinology

authors： Defferrari MS,Da Silva SR,Orchard I,Lange AB

更新日期：2018-12-06 00:00:00

abstract：:[This corrects the article DOI: 10.3389/fendo.2019.00668.]. ...

journal_title：Frontiers in endocrinology

authors： Wee NKY,Lorenz MR,Bekirov Y,Jacquin MF,Scheller EL

更新日期：2020-01-22 00:00:00

abstract：:Recent evidence indicates that autophagy-mediated mitochondrial homeostasis is crucial for oxidative stress-related brain damage and repair. The highest concentration of melatonin is in the mitochondria of cells, and melatonin exhibits well-known antioxidant properties. We investigated the impact and mechanism involve...

journal_title：Frontiers in endocrinology

authors： Wang DD,Jin MF,Zhao DJ,Ni H

更新日期：2019-08-08 00:00:00

abstract：:Obstructive sleep apnea-hypopnea syndrome (OSAHS) is frequently present in patients with severe obesity, but its prevalence especially in women is not well defined. OSAHS and non-alcoholic fatty liver disease are common conditions, frequently associated in patients with central obesity and metabolic syndrome and are b...

journal_title：Frontiers in endocrinology

authors： Scartabelli G,Querci G,Marconi L,Ceccarini G,Piaggi P,Fierabracci P,Salvetti G,Cizza G,Mazzeo S,Vitti J,Berger S,Palla A,Santini F

更新日期：2018-06-06 00:00:00

abstract：:In neuroendocrine cells, prohormones move from the endoplasmic reticulum to the Golgi complex (GC), where they are sorted and packed into secretory granules. The GC is considered the central station of the secretory pathway of proteins and lipids en route to their final destination. In most mammalian cells, it is form...

journal_title：Frontiers in endocrinology

authors： Martínez-Alonso E,Tomás M,Martínez-Menárguez JA

更新日期：2013-03-28 00:00:00

abstract：Introduction:Vitamin D deficiency is an important public health problem worldwide. Vitamin D deficiency confers a significant risk for both skeletal and non-skeletal disorders and a number of lifelong negative health outcomes. The objectives of this evidence-based guidelines document are to provide health care professi...

journal_title：Frontiers in endocrinology

authors： Rusińska A,Płudowski P,Walczak M,Borszewska-Kornacka MK,Bossowski A,Chlebna-Sokół D,Czech-Kowalska J,Dobrzańska A,Franek E,Helwich E,Jackowska T,Kalina MA,Konstantynowicz J,Książyk J,Lewiński A,Łukaszkiewicz J,Marcinowska

更新日期：2018-05-31 00:00:00

abstract：Purpose:To assess whether volumetric vertebral bone mineral density (BMD) measured with opportunistic quantitative computed tomography (QCT) (i.e., CT acquired for other reasons) can predict osteoporotic fracture occurrence in a prospective clinical cohort and how this performs in comparison to dual-energy X-ray absorp...

journal_title：Frontiers in endocrinology

authors： Leonhardt Y,May P,Gordijenko O,Koeppen-Ursic VA,Brandhorst H,Zimmer C,Makowski MR,Baum T,Kirschke JS,Gersing AS,Seifert-Klauss V,Schwaiger BJ

更新日期：2020-11-09 00:00:00

abstract：:Obesity has emerged as one of the most burdensome conditions in modern society. In this context, understanding the mechanisms controlling food intake is critical. At present, the adipocyte-derived hormone leptin and the pancreatic β-cell-derived hormone insulin are considered the principal anorexigenic hormones. Altho...

journal_title：Frontiers in endocrinology

authors： Thon M,Hosoi T,Ozawa K

更新日期：2016-10-20 00:00:00

abstract：Objective:To evaluate whether endometrial thickness (EMT) change in response to progesterone has an effect on pregnancy outcomes in frozen-thawed embryo transfer (FET) cycles. Design:Retrospective observational study. Setting:Tertiary-care academic medical center. Participants:4465 infertile women undergoing their f...

journal_title：Frontiers in endocrinology

authors： Ye J,Zhang J,Gao H,Zhu Y,Wang Y,Cai R,Kuang Y

更新日期：2020-10-29 00:00:00

abstract：:The neurosteroids progesterone and allopregnanolone regulate numerous neuroprotective functions in neural tissues including inhibition of epileptic seizures and cell death. Many of progesterone's actions are mediated through the nuclear progesterone receptor (PR), while allopregnanolone is widely considered to be devo...

journal_title：Frontiers in endocrinology

authors： Thomas P,Pang Y

更新日期：2020-06-24 00:00:00

abstract：:Activation of the hypothalamo-pituitary-adrenal (HPA) axis is a basic reaction of animals to environmental perturbations that threaten homeostasis. These responses are ultimately regulated by neurons residing within the paraventricular nucleus (PVN) of the hypothalamus. Within the PVN, corticotrophin-releasing hormone...

journal_title：Frontiers in endocrinology

authors： Handa RJ,Sharma D,Uht R

更新日期：2011-11-10 00:00:00

abstract：:Besides its interest for diagnosis, the finding of an elevated serum AMH level in PCOS has open major pathophysiological issues. This review addresses the three most important issues: 1- the role of AMH in the disturbed folliculogenesis of PCOS; 2- the role of AMH in the gonadotropin dysregulation of PCOS and 3- the r...

journal_title：Frontiers in endocrinology

authors： Dewailly D,Barbotin AL,Dumont A,Catteau-Jonard S,Robin G

更新日期：2020-09-09 00:00:00

abstract：:Aim: Type 2 Diabetes Mellitus (T2DM) is associated with both microvascular complications such as diabetic retinopathy (DR), and macrovascular complications like coronary artery disease (CAD). Genetic risk factors have a role in the development of these complications. In the present case-control study, we investigated ...

journal_title：Frontiers in endocrinology

authors： Azzam SK,Osman WM,Lee S,Khalaf K,Khandoker AH,Almahmeed W,Jelinek HF,Al Safar HS

更新日期：2019-05-03 00:00:00

abstract：:Parathyroid (PTH) exploration surgery carries the risk of developing post-operative thyroiditis due to vigorous manual manipulation of the thyroid gland during surgery. Post-operative thyroiditis has a wide spectrum of clinical manifestations. However, it remains underreported. Here, we describe a case of post-operati...

journal_title：Frontiers in endocrinology

authors： Hakami YA

更新日期：2015-08-18 00:00:00

abstract：:Human phosphodiesterases (PDEs) comprise a complex superfamily of enzymes derived from 24 genes separated into 11 PDE gene families (PDEs 1-11), expressed in different tissues and cells, including heart and brain. The isoforms PDE4, PDE7, and PDE8 are specific for the second messenger cAMP, which is responsible for me...

journal_title：Frontiers in endocrinology

authors： Bizzi MF,Bolger GB,Korbonits M,Ribeiro-Oliveira A Jr

更新日期：2019-03-19 00:00:00

abstract：:Hard tissue regeneration represents a challenge for the Regenerative Medicine and Mesenchymal stem cells (MSCs) could be a successful therapeutic strategy. T-LysYal® (T-Lys), a new derivative of Hyaluronic Acid (HA) possessing a superior stability, has already been proved efficient in repairing corneal epithelial cell...

journal_title：Frontiers in endocrinology

authors： Di Benedetto A,Posa F,Marazzi M,Kalemaj Z,Grassi R,Lo Muzio L,Comite MD,Cavalcanti-Adam EA,Grassi FR,Mori G

更新日期：2020-05-05 00:00:00

abstract：:Polycystic ovary syndrome (PCOS) is the commonest endocrine abnormality in women of reproductive age typically presenting with chronic oligo- or anovulation, clinical, or biochemical hyperandrogenism and polycystic ovarian morphology (PCOM). Restoring mono-ovulation is the ultimate goal of ovulation induction and most...

journal_title：Frontiers in endocrinology

authors： Laven JSE

更新日期：2019-02-12 00:00:00