The Regulation of Peripheral Metabolism by Gut-Derived Hormones.

abstract：:Endocrine disrupting chemicals (EDCs) are chemicals that interfere with the organizational or activational effects of hormones. Although the vast majority of the EDC literature focuses on steroid hormone signaling related impacts, growing evidence from a myriad of species reveals that the nonapeptide hormones vasopres...

journal_title：Frontiers in endocrinology

authors： Patisaul HB

更新日期：2017-06-19 00:00:00

abstract：:Cholecystokinin (CCK) was discovered in 1928 in jejunal extracts as a gallbladder contraction factor. It was later shown to be member of a peptide family, which are all ligands for the CCK1 and CCK2 receptors. CCK peptides are known to be synthetized in small intestinal endocrine I-cells and cerebral neurons. But in a...

journal_title：Frontiers in endocrinology

authors： Rehfeld JF

更新日期：2017-04-13 00:00:00

abstract：:Background: Previous studies have confirmed that APOE genotype is associated with lipid metabolism, but related studies are inconsistent. Therefore, we conducted this cross-sectional study to explore the associations between apolipoprotein E (APOE) genotypes and serum levels of fasting blood sugar, triglycerides, tota...

journal_title：Frontiers in endocrinology

authors： Li W,Li Y,Qiu Q,Sun L,Yue L,Li X,Xiao S

更新日期：2019-12-05 00:00:00

abstract：Introduction:Obesity is associated with a higher risk of abortion in women undergoing in vitro fertilization (IVF). Whether thrombophilia amplifies this risk is currently unclear. The aim of this study was to evaluate the effects of thrombophilia on the risk of abortion in obese women treated with IVF. Methods:Patient...

journal_title：Frontiers in endocrinology

authors： Candeloro M,Di Nisio M,Ponzano A,Tiboni GM,Potere N,Tana M,Rutjes AWS,Porreca E

更新日期：2020-12-23 00:00:00

abstract：:In some organisms and cells, oxygen availability influences oxygen consumption. In this review, we examine this phenomenon of hypoxic hypometabolism (HH), discussing its features, mechanisms, and implications. Small mammals and other vertebrate species exhibit "oxyconformism," a downregulation of metabolic rate and bo...

journal_title：Frontiers in endocrinology

authors： Gu C,Jun JC

更新日期：2018-11-13 00:00:00

abstract：:Most of the described structures of podocytes in health and disease have been inferred from light and electron microscopic studies of rodent models. The variation in filtration barrier features is measured on micrographs, the aim being statistical significance. This is the technical campaign waged against kidney disea...

journal_title：Frontiers in endocrinology

authors： Neal CR

更新日期：2015-02-23 00:00:00

abstract：:The majority of embryonal tumors or childhood blastomas derive from pluripotent progenitors or fetal stem cells that acquire cancer stem cell (CSC) properties: multipotency, self-renewal ability, metastatic potential, chemoresistance, more pronounced levels of drug transporters, enhanced DNA-damage repair mechanisms, ...

journal_title：Frontiers in endocrinology

authors： Veschi V,Verona F,Thiele CJ

更新日期：2019-11-19 00:00:00

abstract：:Objective: Soy and cocoa have been suggested to be beneficial for diabetes. The aim of this study was to identify the effects of soy protein, isoflavones, and cocoa on glycemic control parameters. Research design and methods: The study was a parallel, double-blind, placebo-controlled study where patients with diet or ...

journal_title：Frontiers in endocrinology

authors： Konya J,Sathyapalan T,Kilpatrick ES,Atkin SL

更新日期：2019-05-09 00:00:00

abstract：:The 3D arrangement of porous granular biomaterials usable to fill bone defects has received little study. Granular biomaterials occupy 3D space when packed together in a manner that creates a porosity suitable for the invasion of vascular and bone cells. Granules of beta-tricalcium phosphate (β-TCP) were prepared with...

journal_title：Frontiers in endocrinology

authors： Chappard D,Terranova L,Mallet R,Mercier P

更新日期：2015-10-12 00:00:00

abstract：:Introduction: Secondary hyperparathyroidism (sHPT) is a common hormonal complication of chronic kidney disease. There are several therapeutic options for sHPT management aiming at calcium-phosphorus balance normalization and decrease of parathormone secretion. Objectives: The aim of this retrospective, observational s...

journal_title：Frontiers in endocrinology

authors： Zawierucha J,Malyszko J,Malyszko JS,Prystacki T,Marcinkowski WP,Dryl-Rydzynska T

更新日期：2019-02-05 00:00:00

abstract：:Thyroid nodules with ultrasound (US) cancer risk features and extra-thyroid lesions suggesting malignant lymph nodes, require prompt diagnosis, especially in children. The US pattern of intrathyroidal ectopic thymus (IET) can strongly suggest papillary thyroid carcinoma (PTC). The extra-thyroid ectopic thymic tissue (...

journal_title：Frontiers in endocrinology

authors： Stasiak M,Adamczewski Z,Stawerska R,Krawczyk T,Tomaszewska M,Lewiński A

更新日期：2019-04-10 00:00:00

abstract：:Introduction: Pituitary metastases (PM) are rare events and to date only very few cases of melanoma PM have been described in literature up to now. Case Presentation: We describe the clinical history of a 33-year-old male patient who underwent surgical excision of an inter-scapular melanoma in 2008. The subsequent fol...

journal_title：Frontiers in endocrinology

authors： Mormando M,Puliani G,Barnabei A,Lauretta R,Bianchini M,Chiefari A,Russillo M,Cognetti F,Romano L,Appetecchia M

更新日期：2020-07-23 00:00:00

abstract：:The brain is composed of neurons and non-neuronal cells, with the latter encompassing glial, ependymal and endothelial cells, as well as pericytes and progenitor cells. Studies aimed at understanding how the brain operates have traditionally focused on neurons, but the importance of non-neuronal cells has become incre...

journal_title：Frontiers in endocrinology

authors： Argente-Arizón P,Freire-Regatillo A,Argente J,Chowen JA

更新日期：2015-03-26 00:00:00

abstract：:The insulin signaling pathway is a modulator of metabolism in insects and can regulate functions associated with growth and development, as well as lipid and carbohydrate balance. We have previously reported the presence of an insulin-like peptide and an insulin-like growth factor in Rhodnius prolixus, which are invol...

journal_title：Frontiers in endocrinology

authors： Defferrari MS,Da Silva SR,Orchard I,Lange AB

更新日期：2018-12-06 00:00:00

abstract：:[This corrects the article DOI: 10.3389/fendo.2017.00018.]. ...

journal_title：Frontiers in endocrinology

authors： Sekar R,Wang L,Chow BKC

更新日期：2018-07-18 00:00:00

abstract：:Molecular mechanisms responsible for gonadotrophic control of ovarian follicle development and ovulation have not been fully delineated. In this study, prepubertal female rabbits were subjected to a combined PMSG/hCG treatment for the induction of follicle maturation and ovulation. Ovaries of 6 does at different time ...

journal_title：Frontiers in endocrinology

authors： Hu S,Liang X,Ren X,Shi Y,Su H,Li Y,Du K,Wang J,Jia X,Chen S,Lai S

更新日期：2019-10-29 00:00:00

abstract：:The orexigenic peptide hormone ghrelin is synthesized in the stomach and its receptor growth hormone secretagogue receptor (GHSR1a) is expressed mainly in the central nervous system (CNS). In this review, we confine our discussion to the physiological role of GHSR1a in the brain. Paradoxically, despite broad expressio...

journal_title：Frontiers in endocrinology

authors： Kern A,Grande C,Smith RG

更新日期：2014-08-18 00:00:00

abstract：:The insulin/IGF system plays an important role in cancer progression. Accordingly, elevated levels of circulating insulin have been associated with an increased cancer risk as well as with aggressive and metastatic cancer phenotypes. Numerous studies have documented that estrogens cooperate with the insulin/IGF system...

journal_title：Frontiers in endocrinology

authors： De Marco P,Cirillo F,Vivacqua A,Malaguarnera R,Belfiore A,Maggiolini M

更新日期：2015-03-06 00:00:00

abstract：:Diabetes is a worldwide public health concern as it is associated with various complications. One of the major complications of diabetes is diabetic foot syndrome that results in catastrophic events such as ulceration and amputation. Therefore, the main four strategies of diabetic foot care involve risk prediction, pr...

journal_title：Frontiers in endocrinology

authors： Balasubramanian G,Vas P,Chockalingam N,Naemi R

更新日期：2020-05-22 00:00:00

abstract：:The essential amino acid L-tryptophan (Trp) is the precursor of the monoaminergic neurotransmitter serotonin (5-hydroxytryptamine, 5-HT). Numerous studies have shown that elevated dietary Trp has a suppressive effect on aggressive behavior and post-stress plasma cortisol concentrations in vertebrates, including teleos...

journal_title：Frontiers in endocrinology

authors： Höglund E,Øverli Ø,Winberg S

更新日期：2019-04-08 00:00:00

abstract：:The estimated number of testicular olfactory receptors (ORs) in mammals range between 20 and 66. Previous data reported the role of hOR17-4 and mOR23 in sperm-oocyte chemiotaxis. Proteomic analysis was performed to understand which are the ORs expressed in seminal plasma. Seminal samples by four fertile men were analy...

journal_title：Frontiers in endocrinology

authors： Milardi D,Colussi C,Grande G,Vincenzoni F,Pierconti F,Mancini F,Baroni S,Castagnola M,Marana R,Pontecorvi A

更新日期：2018-01-23 00:00:00

abstract：:The p53-related gene p63 is required for epithelial cell establishment and its expression is often altered in tumor cells. Great strides have been made in understanding the pathways and mechanisms that regulate p63 levels, such as the Wnt, Hedgehog, Notch, and EGFR pathways. We discuss here the multiple signaling path...

journal_title：Frontiers in endocrinology

authors： Yoh K,Prywes R

更新日期：2015-04-28 00:00:00

abstract：Objective:Individuals with diabetic peripheral neuropathy (DPN) have functional deficits that increase their risk of falling. However, psychological aspects such as loss of confidence in undertaking activities could also contribute to this risk. We examined correlations between balance confidence and fall risk among in...

journal_title：Frontiers in endocrinology

authors： Riandini T,Khoo EYH,Tai BC,Tavintharan S,Phua MSLA,Chandran K,Hwang SW,Venkataraman K

更新日期：2020-10-23 00:00:00

abstract：:Gonadotropin-releasing hormone (GnRH) is the primary regulator of mammalian reproductive function in both males and females. It acts via G-protein coupled receptors on gonadotropes to stimulate synthesis and secretion of the gonadotropin hormones luteinizing hormone and follicle-stimulating hormone. These receptors co...

journal_title：Frontiers in endocrinology

authors： Perrett RM,McArdle CA

更新日期：2013-11-20 00:00:00

abstract：:Over the past decade, the increasing prevalence of obesity and its associated metabolic disorders constitutes one of the most concerning healthcare issues for countries worldwide. In an effort to curb the increased mortality and morbidity derived from the obesity epidemic, various therapeutic strategies have been deve...

journal_title：Frontiers in endocrinology

authors： Ong BX,Brunmeir R,Zhang Q,Peng X,Idris M,Liu C,Xu F

更新日期：2020-02-27 00:00:00

abstract：:Background: The number of subjects with gender dysphoria has been increasing. In general, male-to-female transsexual subjects are treated with estradiol valerate therapy. In this report, we showed the time course of ACTH and cortisol levels after estradiol valerate injection in a male subject with gender dysphoria. It...

journal_title：Frontiers in endocrinology

authors： Anno T,Kawasaki F,Shigemoto R,Irie S,Mune T,Kaku K,Kaneto H

更新日期：2019-11-05 00:00:00

abstract：:Pregnancy-associated plasma protein-A (PAPP-A) and its homolog PAPP-A2 are enzymes that modulate the availability and mitogenic activity of insulin-like growth factor-I (IGF-I). PAPP-A has been implicated in numerous cancers but reports on PAPP-A2 in malignancy are non-existent. In a prospective observational study of...

journal_title：Frontiers in endocrinology

authors： Hjortebjerg R,Espelund U,Rasmussen TR,Folkersen B,Steiniche T,Georgsen JB,Oxvig C,Frystyk J

更新日期：2020-09-02 00:00:00

abstract：:Interferon gamma (IFNγ) is a Th1 cytokine that is critical for innate and adaptive immunity. Toll-like receptors (TLRs) signaling pathways are critical in early host defense against invading pathogens. miR-146a has been reported to participate in the regulation of host immunity. The known mechanisms of integrations be...

journal_title：Frontiers in endocrinology

authors： Peng W,Sun Y,Li GF,He LG,Li RZ,Liang YS,Ding X,Yu X,Zhang Y,Lin HR,Lu DQ

更新日期：2018-02-26 00:00:00

abstract：Background:In addition to inborn metabolic disorders, altered metabolic profiles were reported to be associated with the risk and prognosis of some non-metabolic diseases, while as a rare metabolic disease, the overall secondary metabolic spectrum in congenital hyperinsulinemic hypoglycemia (HH) is largely undetermined...

journal_title：Frontiers in endocrinology

authors： Xu ZR,Zhu XY,Lu W,Sun WH,Cheng RQ,Ni JW,Xi L,Hussain K,Luo FH,Zhang MY

更新日期：2020-10-08 00:00:00

abstract：:Activation of the hypothalamo-pituitary-adrenal (HPA) axis is a basic reaction of animals to environmental perturbations that threaten homeostasis. These responses are ultimately regulated by neurons residing within the paraventricular nucleus (PVN) of the hypothalamus. Within the PVN, corticotrophin-releasing hormone...

journal_title：Frontiers in endocrinology

authors： Handa RJ,Sharma D,Uht R

更新日期：2011-11-10 00:00:00