Absence of HBV Reactivation in Patients With Resolved HBV Infection Following DAA Therapy for Hepatitis C: A 1-Year Follow-up Study.

abstract：Background:In December 2018, a large, tertiary, university-affiliated hospital in the Philippines discovered that their legitimate supply chain was infiltrated with counterfeit rabies vaccines. Methods:All vials suspected to be counterfeit were quarantined and surrendered to the Philippine Food and Drug Administration...

journal_title：Open forum infectious diseases

authors： Henson KER,Santiago AAC,Namqui SS

更新日期：2020-07-22 00:00:00

abstract：:Background.  Varicella is a highly contagious vaccine-preventable illness. In 1996, the Advisory Committee for Immunization Practices recommended 1 dose of vaccine for children, and in 2006 it recommended 2 doses; Connecticut required 1 dose for school entry in 2000 and 2 doses for school entry starting in 2011. Conne...

journal_title：Open forum infectious diseases

authors： Mullins J,Kudish K,Sosa L,Hadler J

更新日期：2015-10-09 00:00:00

abstract：:Background.  Advanced fibrosis occurs more commonly in human immunodeficiency virus (HIV)-hepatitis B virus (HBV) coinfected individuals; therefore, fibrosis monitoring is important in this population. However, transient elastography (TE) data in HIV-HBV coinfection are lacking. We aimed to assess liver fibrosis using...

journal_title：Open forum infectious diseases

authors： Audsley J,Robson C,Aitchison S,Matthews GV,Iser D,Sasadeusz J,Lewin SR

更新日期：2016-02-12 00:00:00

abstract：Background:Irritable bowel syndrome (IBS) is a chronic and debilitating functional gastrointestinal disorder affecting 9%-23% of the population across the world. The relative efficacy of fecal microbiota transplantation (FMT) on IBS symptoms was demonstrated in a double-blind, randomized study. Methods:We describe the...

journal_title：Open forum infectious diseases

authors： Hocquart M,Pham T,Kuete E,Tomei E,Lagier JC,Raoult D

更新日期：2019-10-14 00:00:00

abstract：:Persistent viral activity may cause enduring seropositivity and inflammation in treated people with HIV (PWH). We compared inflammatory biomarkers between early treated PWH who remained seronegative or seroconverted and found similar levels of D-dimer, soluble cluster of differentiation 14, C-reactive protein, and int...

journal_title：Open forum infectious diseases

authors： Cai CW,Pinyakorn S,Kroon E,de Souza M,Colby DJ,Pankam T,Pattanachaiwit S,Ubolyam S,Rupert A,Lallemand P,Dewar R,Highbarger HC,Ananworanich J,Vasan S,Sereti I

更新日期：2020-08-26 00:00:00

abstract：:Symptomatic acute HCV infection and interferon lambda 4 (IFNL4) genotypes are important predictors of spontaneous viral clearance. Using data from a multicohort database (Injecting Cohorts [InC3] Collaborative), we establish an independent association between host IFNL4 genotype and symptoms of acute hepatitis C virus...

journal_title：Open forum infectious diseases

authors： Page K,Mirzazadeh A,Rice TM,Grebely J,Kim AY,Cox AL,Morris MD,Hellard M,Bruneau J,Shoukry NH,Dore GJ,Maher L,Lloyd AR,Lauer G,Prins M,McGovern BH

更新日期：2016-02-08 00:00:00

abstract：:Thrombocytopenia is a characteristic feature during the acute phase of dengue infection and has been found to associate with vascular leakage in severe dengue. Although dengue antigens have been observed in platelets, there is no strong evidence to suggest a direct infection of platelets by dengue virus as a contribut...

journal_title：Open forum infectious diseases

authors： Kar M,Singla M,Chandele A,Kabra SK,Lodha R,Medigeshi GR

更新日期：2017-03-23 00:00:00

abstract：Background:The 4-component capsular group B meningococcal vaccine (4CMenB) was licensed as a 4-dose infant schedule but introduced into the United Kingdom as 3 doses at 2, 4, and 12 months of age. We describe the immunogenicity and reactogenicity of the 2 + 1 schedule in infants. Methods:Infants were randomized to rec...

journal_title：Open forum infectious diseases

authors： Valente Pinto M,O'Connor D,Galal U,Clutterbuck EA,Robinson H,Plested E,Bibi S,Camara Pellisso S,Hughes H,Kerridge S,Mujadidi YF,Findlow H,Borrow R,Snape MD,Pollard AJ

更新日期：2020-04-29 00:00:00

abstract：:The year 2019 brought about a multitude of innovations in clinical infectious diseases. With the continued rise of antimicrobial resistance (AMR), advances in diagnostics and newly available antibiotics offer additional strategies for combating this threat, but the broken antibiotic market serves as an impediment to f...

journal_title：Open forum infectious diseases

authors： Moss S,Boucher HW

更新日期：2020-03-23 00:00:00

abstract：Background:Staphylococcus aureus is the most common cause of native septic arthritis. Few studies have characterized this disease during the US opioid epidemic. The role of methicillin-resistant Staphylococcus aureus (MRSA) nasal screening in this disease has not been elucidated. We sought to identify risk factors and ...

journal_title：Open forum infectious diseases

authors： Gobao VC,Alfishawy M,Smith C,Byers KE,Yassin M,Urish KL,Shah NB

更新日期：2020-12-18 00:00:00

abstract：:Background.  Sepsis is a major cause of morbidity and mortality among older adults. The main goals of this study were to assess the association of sepsis at intensive care unit (ICU) admission with mortality and to identify predictors associated with increased mortality in older adults. Methods.  We conducted a prospe...

journal_title：Open forum infectious diseases

authors： Rowe T,Araujo KL,Van Ness PH,Pisani MA,Juthani-Mehta M

更新日期：2016-01-21 00:00:00

abstract：Background:Recent observations provide evidence for group-specific immunity toward influenza A infections and raise the question of how often we can get the flu. Methods:We retrospectively analyzed 2308 cases of children and adolescents with clinically manifested influenza and a positive PCR-test during the last 4 epi...

journal_title：Open forum infectious diseases

authors： Möst J,Redlberger-Fritz M,Weiss G

更新日期：2019-04-23 00:00:00

abstract：Background:Cytomegalovirus (CMV) mononucleosis is a manifestation of primary CMV infection. This study aims to establish the link between long-term population CMV seroepidemiological trends and incidence of CMV mononucleosis requiring hospitalization. Furthermore, by analyzing serial laboratory data of patients hospita...

journal_title：Open forum infectious diseases

authors： Sridhar S,Chung TWH,Chan JFW,Cheng VCC,Lau SKP,Yuen KY,Woo PCY

更新日期：2018-10-20 00:00:00

abstract：:Among a cohort of men who have sex with men in a pre-exposure prophylaxis (PrEP) adherence trial, syphilis requiring treatment was associated with white coat dosing (increased PrEP adherence immediately preceding study visits) when compared with participants with optimal drug concentrations. The findings highlight the...

journal_title：Open forum infectious diseases

authors： Blair CS,Beymer MR,Kofron RM,Bolan RK,Jordan WC,Haubrich RH,Wohl AR,Landovitz RJ

更新日期：2020-08-07 00:00:00

abstract：Background:In 2012, the US Food and Drug Administration (FDA) required drug manufacturers to give advance notice of impending drug shortages. A survey of infectious diseases (ID) physicians was undertaken to determine the impact of this requirement and to follow-up on prior perceptions of ID physicians on shortages of ...

journal_title：Open forum infectious diseases

authors： Gundlapalli AV,Beekmann SE,Graham DR,Polgreen PM,Members of the Emerging Infections Network.

更新日期：2018-04-23 00:00:00

abstract：Background:Coagulation activity among persons with HIV is associated with end-organ disease risk, but the pathogenesis is not well characterized. We tested a hypothesis that hypercoagulation contributes to disease risk, in part, via upregulation of inflammation. Methods:Treatment effects of edoxaban (30 mg), a direct ...

journal_title：Open forum infectious diseases

authors： Baker JV,Wolfson J,Peterson T,Mooberry M,Gissel M,Mystakelis H,Henderson MW,Garcia-Myers K,Rhame FS,Schacker TW,Brummel-Ziedins KE,Sereti I,Key NS,Tracy RP

更新日期：2020-02-01 00:00:00

abstract：: Background.  Many human immunodeficiency virus (HIV)-infected patients remain on nevirapine-based antiretroviral therapy (ART) despite safety and efficacy concerns. Switching to a rilpivirine-based regimen is an alternative, but there is little experience with rilpivirine ...

journal_title：Open forum infectious diseases

authors： Collins SE,Grant PM,Uwinkindi F,Talbot A,Seruyange E,Slamowitz D,Mugeni A,Remera E,Niyonsenga SP,Nyirimigabo J,Uwizihiwe JP,Dongier P,Muhayimpundu R,Mazarati JB,Zolopa A,Nsanzimana S

更新日期：2016-07-01 00:00:00

abstract：:We present a case of an unvaccinated traveler who traveled from New York to Peru and contracted yellow fever. He likely acquired the infection while visiting the Amazon River, with a point of exit of Lima, Peru. Our case illustrates the dramatic course that yellow fever may take, as well as the importance of pretravel...

journal_title：Open forum infectious diseases

authors： Winnicka L,Abdullah A,Yang T,Norville K,Irizarry-Acosta M

更新日期：2017-12-20 00:00:00

abstract：:Patients with Mycobacterium avium complex lung disease treated with amikacin liposome inhalation suspension (ALIS) at 2 clinics in the United States were surveyed to assess the frequency and management of ALIS-associated respiratory adverse events. Most respondents experienced these events, but management through phys...

journal_title：Open forum infectious diseases

authors： Swenson C,Lapinel NC,Ali J

更新日期：2020-03-02 00:00:00

abstract：:This study evaluated health outcomes among people who inject drugs who are infected with hepatitis C virus using an artificial intelligence platform. Mean (SD) cumulative adherence (visual confirmation of administration) was 91.3% (10.5%). Most subjects (88.2%) achieved ≥80% adherence to treatment, and 88.2% (15 of 17...

journal_title：Open forum infectious diseases

authors： Litwin AH,Shafner L,Norton B,Akiyama MJ,Agyemang L,Guzman M,Vera T,Heo M

更新日期：2020-07-20 00:00:00

abstract：BACKGROUND:Invasive group A Streptococcus (iGAS) disease caused by type emm89 strains has been increasing worldwide, driven by the emergence of an epidemic clonal variant (clade 3 emm89). The clinical characteristics of patients with emm89 iGAS disease, and in particular with clade 3 emm89 iGAS disease, are poorly desc...

journal_title：Open forum infectious diseases

authors： Teatero S,Coleman BL,Beres SB,Olsen RJ,Kandel C,Reynolds O,Athey TBT,Musser JM,McGeer A,Fittipaldi N

更新日期：2017-03-04 00:00:00

abstract：:Background.  Histoplasmosis causes severe disease in patients with defects of cell-mediated immunity. It is not known whether outcomes vary related to the type of immunodeficiency or class of antifungal treatment. Methods.  We reviewed cases of active histoplasmosis that occurred at Vanderbilt University Medical Cente...

journal_title：Open forum infectious diseases

authors： Luckett K,Dummer JS,Miller G,Hester S,Thomas L

更新日期：2015-02-20 00:00:00

abstract：:A 7-year-old child of Turkish origin presented with headache and vomiting in the context of prolonged fever of unknown source. At examination, oral candidiasis and chronic onychomycosis were noted. A Candida meningoencephalitis was diagnosed and intravenous Amphotericin B liposomal was given during 6 months relayed by...

journal_title：Open forum infectious diseases

authors： Martin S,Balligand E,Peeters J,Nassogne MC,Mondovits B,Loop M,de Selys A,Vanclaire J,Vermylen C,De Bruyckere JJ,Chatzis O,Puel A,Gilliaux O,Van Der Linden D

更新日期：2019-11-03 00:00:00

abstract：:Burkholderia pseudomallei and Burkholderia cepacia complex are poorly studied in Mexico. The genotypic analysis of 38 strains isolated from children with pneumonia were identified and showed that both Burkholderia groups were present in patients. From our results, it is plausible to suggest that new species are among ...

journal_title：Open forum infectious diseases

authors： Meza-Radilla G,Mendez-Canarios A,Xicohtencatl-Cortes J,Escobedo-Guerra MR,Torres AG,Ibarra JA,Estrada-de Los Santos P

更新日期：2019-01-18 00:00:00

abstract：BACKGROUND:Intra-abdominal infections (IAI) constitute a common reason for hospitalization. However, there is lack of standardization in empiric management of (1) anaerobes, (2) enterococci, (3) fungi, and (4) multidrug-resistant organisms (MDRO). The recommendation is to institute empiric coverage for some of these or...

journal_title：Open forum infectious diseases

authors： Marcus G,Levy S,Salhab G,Mengesha B,Tzuman O,Shur S,Burke E,Mayeda RC,Cochavi L,Perluk I,Zaidenstein R,Lazarovitch T,Dadon M,Marchaim D

更新日期：2016-12-20 00:00:00

abstract：:Although it is intuitive that antibiotics administered before obtaining a blood culture would reduce the likelihood of obtaining a positive culture, it is not clear exactly how rapidly and to what extent blood becomes sterile after administration of intravenous (IV) antibiotics. Using a large data set of patients admi...

journal_title：Open forum infectious diseases

authors： Rand KH,Beal SG,Rivera K,Allen B,Payton T,Lipori GP

更新日期：2019-05-20 00:00:00

abstract：: Background.  Herpes zoster, or shingles, is a common, painful reactivation of latent varicella zoster virus infection. Understanding host factors that predispose to herpes zoster may permit development of more effective prevention strategies. Our objective was to examine m...

journal_title：Open forum infectious diseases

authors： Levinson RT,Hulgan T,Kalams SA,Fessel JP,Samuels DC

更新日期：2016-10-19 00:00:00

abstract：Background:To determine the effectiveness of implementing a locally developed clinical practice guideline (CPG) for antibiotic treatment in adults with community-acquired cellulitis at Siriraj Hospital in Bangkok, Thailand. Methods:The CPG for antibiotic treatment of community-acquired cellulitis was developed based o...

journal_title：Open forum infectious diseases

authors： Sirijatuphat R,Nookeu P,Thamlikitkul V

更新日期：2020-09-07 00:00:00

abstract：Background:Patients heterozygous for mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene may be more susceptible to respiratory infections than the general population. Methods :We conducted a retrospective case-control study using health insurance claims. We identified patients as either h...

journal_title：Open forum infectious diseases

authors： Polgreen PM,Brown GD,Hornick DB,Ahmad F,London B,Stoltz DA,Comellas AP

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Monitoring of immune function, measured by CD4 cell count, is an essential service for people with Human Immunodeficiency Virus (HIV). Prescription of antiretroviral (ARV) medications is contingent on CD4 cell count; patients without regular CD4 monitoring are unlikely to receive ARVs when indicated. This st...

journal_title：Open forum infectious diseases

authors： Davis AC,Watson G,Pourat N,Kominski GF,Roby DH

更新日期：2014-06-05 00:00:00