Abstract:
BACKGROUND:Pancreaticoduodenectomy (PD) is a complex surgical procedure with a high morbidity rate. The serious complications are major risk factors for poor long-term surgical outcome. Studies have reported an association between early postoperative prognostic nutritional index (PNI) and prediction of severe complications after abdominal surgery. However, there have been no studies on the use of early postoperative PNI for predicting serious complications following PD. AIM:To analyze the risk factors and early postoperative PNI for predicting severe complications following PD. METHODS:We retrospectively analyzed 238 patients who underwent PD at our hospital between January 2007 and December 2017. The postoperative complications were classified according to the Dindo-Clavien classification. Grade III-V postoperative complications were classified as serious. The risk factors for serious complications were analyzed by univariate analysis and multivariate logistic regression analysis. RESULTS:Overall complications were detected in 157 of 238 patients (65.9%) who underwent PD. The grade III-V complication rate was 26.47% (63/238 patients). The mortality rate was 3.7% (9/238 patients). Multivariate logistic regression analysis revealed that preoperative serum albumin [odds ratio (OR): 0.883, 95% confidence interval (CI): 0.80-0.96; P < 0.01] and PNI on postoperative day 3 < 40.5 (OR: 2.77, 95%CI: 1.21-6.38, P < 0.05) were independent factors associated with grade III-V postoperative complications. CONCLUSION:Perioperative albumin is an important factor associated with serious complications following PD. Low early postoperative PNI (< 40.5) is a predictor for serious complications.
journal_name
World J Clin Casesjournal_title
World journal of clinical casesauthors
Rungsakulkij N,Tangtawee P,Suragul W,Muangkaew P,Mingphruedhi S,Aeesoa Sdoi
10.12998/wjcc.v7.i1.28subject
Has Abstractpub_date
2019-01-06 00:00:00pages
28-38issue
1issn
2307-8960journal_volume
7pub_type
杂志文章abstract:BACKGROUND:The prognosis of paediatric primary refractory/relapsed acute myeloid leukaemia (R/R AML) remains poor. Intensive therapy is typically used as salvage treatment for those with R/R AML. No data are currently available about the use of the CLAG-M protocol as salvage therapy in paediatric patients with R/R AML....
journal_title:World journal of clinical cases
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abstract:BACKGROUND:Type A insulin resistance syndrome is a rare disorder caused by mutations in the gene encoding the insulin receptor. Its coexistence with ovarian serous papillary cystadenofibroma is even rarer. CASE SUMMARY:A 14-year-old girl developed type A insulin resistance syndrome and showed high fasting insulin, glu...
journal_title:World journal of clinical cases
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abstract::Dysbetalipoproteinemia is a rare familial dyslipidemia characterized by approximately equally elevated serum cholesterol and triglyceride levels due to accumulated remnant lipoproteins in apolipoprotein E2/E2 homozygotes. It is associated with an increased risk for premature cardiovascular disease. Thus, making a diag...
journal_title:World journal of clinical cases
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journal_title:World journal of clinical cases
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abstract:BACKGROUND:Fetal akinesia deformation sequence (FADS) is a broad spectrum disorder with absent fetal movements as the unifying feature. The etiology of FADS is heterogeneous and mostly still unknown. A prenatal diagnosis of FADS relies on clinical features obtained by ultrasound and fetal muscle pathology. However, the...
journal_title:World journal of clinical cases
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abstract::Inflammatory bowel disease (IBD) is a chronic immune-mediated disease that affects the gastrointestinal tract. It is argued that environment, microbiome, and immune-mediated factors interact in a genetically susceptible host to trigger IBD. Recently, there has been increased interest in the development, progression, a...
journal_title:World journal of clinical cases
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journal_title:World journal of clinical cases
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journal_title:World journal of clinical cases
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journal_title:World journal of clinical cases
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journal_title:World journal of clinical cases
pub_type:
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journal_title:World journal of clinical cases
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journal_title:World journal of clinical cases
pub_type:
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更新日期:2020-03-26 00:00:00
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journal_title:World journal of clinical cases
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journal_title:World journal of clinical cases
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更新日期:2020-12-06 00:00:00
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journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v7.i1.109
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journal_title:World journal of clinical cases
pub_type: 杂志文章,评审
doi:10.12998/wjcc.v3.i6.504
更新日期:2015-06-16 00:00:00
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journal_title:World journal of clinical cases
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journal_title:World journal of clinical cases
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更新日期:2020-02-26 00:00:00
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journal_title:World journal of clinical cases
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pub_type: 杂志文章
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更新日期:2020-12-06 00:00:00
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journal_title:World journal of clinical cases
pub_type:
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更新日期:2019-02-06 00:00:00
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journal_title:World journal of clinical cases
pub_type: 杂志文章
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journal_title:World journal of clinical cases
pub_type: 杂志文章
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journal_title:World journal of clinical cases
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journal_title:World journal of clinical cases
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journal_title:World journal of clinical cases
pub_type: 杂志文章
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journal_title:World journal of clinical cases
pub_type:
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更新日期:2019-01-26 00:00:00