Abstract:
BACKGROUND:Pancreaticoduodenectomy (PD) is a complex surgical procedure with a high morbidity rate. The serious complications are major risk factors for poor long-term surgical outcome. Studies have reported an association between early postoperative prognostic nutritional index (PNI) and prediction of severe complications after abdominal surgery. However, there have been no studies on the use of early postoperative PNI for predicting serious complications following PD. AIM:To analyze the risk factors and early postoperative PNI for predicting severe complications following PD. METHODS:We retrospectively analyzed 238 patients who underwent PD at our hospital between January 2007 and December 2017. The postoperative complications were classified according to the Dindo-Clavien classification. Grade III-V postoperative complications were classified as serious. The risk factors for serious complications were analyzed by univariate analysis and multivariate logistic regression analysis. RESULTS:Overall complications were detected in 157 of 238 patients (65.9%) who underwent PD. The grade III-V complication rate was 26.47% (63/238 patients). The mortality rate was 3.7% (9/238 patients). Multivariate logistic regression analysis revealed that preoperative serum albumin [odds ratio (OR): 0.883, 95% confidence interval (CI): 0.80-0.96; P < 0.01] and PNI on postoperative day 3 < 40.5 (OR: 2.77, 95%CI: 1.21-6.38, P < 0.05) were independent factors associated with grade III-V postoperative complications. CONCLUSION:Perioperative albumin is an important factor associated with serious complications following PD. Low early postoperative PNI (< 40.5) is a predictor for serious complications.
journal_name
World J Clin Casesjournal_title
World journal of clinical casesauthors
Rungsakulkij N,Tangtawee P,Suragul W,Muangkaew P,Mingphruedhi S,Aeesoa Sdoi
10.12998/wjcc.v7.i1.28subject
Has Abstractpub_date
2019-01-06 00:00:00pages
28-38issue
1issn
2307-8960journal_volume
7pub_type
杂志文章abstract:BACKGROUND:In rare cases, odontogenic keratocysts (ODs) transform into squamous cell carcinoma. Intervals between the first attendance of a patient and the diagnosis of OD with malignant transformation vary from weeks to years. In this article, we report a case of malignancy derived from OD with a five-day delay in dia...
journal_title:World journal of clinical cases
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journal_title:World journal of clinical cases
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journal_title:World journal of clinical cases
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journal_title:World journal of clinical cases
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journal_title:World journal of clinical cases
pub_type: 杂志文章
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journal_title:World journal of clinical cases
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journal_title:World journal of clinical cases
pub_type: 杂志文章
doi:10.12998/wjcc.v8.i13.2802
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journal_title:World journal of clinical cases
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pub_type:
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journal_title:World journal of clinical cases
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journal_title:World journal of clinical cases
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journal_title:World journal of clinical cases
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journal_title:World journal of clinical cases
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journal_title:World journal of clinical cases
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journal_title:World journal of clinical cases
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pub_type: 杂志文章,评审
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