Manganese-Enhanced Magnetic Resonance Imaging: Overview and Central Nervous System Applications With a Focus on Neurodegeneration.

abstract：:Verbal fluency is the ability to produce a satisfying sequence of spoken words during a given time interval. The core of verbal fluency lies in the capacity to manage the executive aspects of language. The standard scores of the semantic verbal fluency test are broadly used in the neuropsychological assessment of the ...

journal_title：Frontiers in aging neuroscience

authors： Bertola L,Mota NB,Copelli M,Rivero T,Diniz BS,Romano-Silva MA,Ribeiro S,Malloy-Diniz LF

更新日期：2014-07-29 00:00:00

abstract：INTRODUCTION:Cross-sectional studies have identified long chain omega-3 polyunsaturated fatty acids (eicosapentaenoic acid 20:5n-3 and docosahexaenoic acid 22:6n-3 (O3PUFA) in association with fewer white matter lesions and better executive function in older adults. We hypothesized that O3PUFA are associated with less ...

journal_title：Frontiers in aging neuroscience

authors： Bowman GL,Dodge HH,Mattek N,Barbey AK,Silbert LC,Shinto L,Howieson DB,Kaye JA,Quinn JF

更新日期：2013-12-16 00:00:00

abstract：:Tinnitus, the phantom perception of sound without a corresponding external sound, is a frequent disorder which causes significant morbidity. So far there is no treatment available that reliably reduces the tinnitus perception. The research is hampered by the large heterogeneity of tinnitus and the fact that the tinnit...

journal_title：Frontiers in aging neuroscience

authors： Schlee W,Pryss RC,Probst T,Schobel J,Bachmeier A,Reichert M,Langguth B

更新日期：2016-12-15 00:00:00

abstract：:This randomized controlled study (ClinicalTrials.gov NCT02007616) investigated the maintenance of training effects of 20 1-hr non-action video game training sessions with selected games from a commercial package on several age-declining cognitive functions and subjective wellbeing after a 3-month no-contact period. Tw...

journal_title：Frontiers in aging neuroscience

authors： Ballesteros S,Mayas J,Prieto A,Toril P,Pita C,Laura Pde L,Reales JM,Waterworth JA

更新日期：2015-04-14 00:00:00

abstract：:Latin-American people with dementia will increase to an astounding 368% in 2050, higher than USA and Europe. In addition, to sporadic dementia type like Alzheimer, and vascular dementia (VaD) progression after Cerebrovascular disease is also found. These incidences are increased in Colombia by specific populations aff...

journal_title：Frontiers in aging neuroscience

authors： Cardona-Gómez GP,Lopera F

更新日期：2016-12-20 00:00:00

abstract：:Similar to humans, the normal aged rat population is not homogeneous in terms of cognitive function. Two distinct subpopulations of aged Sprague-Dawley rats can be identified on the basis of spatial memory performance in the hole-board paradigm. It was the aim of the study to reveal protein changes relevant to aging a...

journal_title：Frontiers in aging neuroscience

authors： Lubec J,Smidak R,Malikovic J,Feyissa DD,Korz V,Höger H,Lubec G

更新日期：2019-07-31 00:00:00

abstract：:The association between decline in physical function and age-related conditions, such as reduced cognitive performance and vascular disease, may be explained by genetic influence on shared biological pathways of importance for aging. The apolipoprotein E (APOE) gene is well-known for its association with Alzheimer's d...

journal_title：Frontiers in aging neuroscience

authors： Skoog I,Hörder H,Frändin K,Johansson L,Östling S,Blennow K,Zetterberg H,Zettergren A

更新日期：2016-10-04 00:00:00

abstract：:Background: Amnestic mild cognitive impairment (aMCI) is a heterogeneous condition. Based on clinical symptoms, aMCI could be categorized into single-domain aMCI (SD-aMCI, only memory deficit) and multi-domain aMCI (MD-aMCI, one or more cognitive domain deficit). As core intrinsic functional architecture, inter-hemisp...

journal_title：Frontiers in aging neuroscience

authors： Luo X,Li K,Zeng Q,Huang P,Jiaerken Y,Qiu T,Xu X,Zhou J,Xu J,Zhang M

更新日期：2018-06-05 00:00:00

abstract：:This internal representation of movement of part(s) of the body is involved during Implicit Motor Imagery tasks (IMI); the same representations are employed in the laterality judgment task. Few studies have looked at the consequences of aging, Alzheimer's disease (AD) and mild cognitive impairment (MCI) on the process...

journal_title：Frontiers in aging neuroscience

authors： Bourrelier J,Kubicki A,Rouaud O,Crognier L,Mourey F

更新日期：2015-12-23 00:00:00

abstract：:Neurofilament light (NFL) is a putative biomarker of neurodegeneration. This study evaluates the correlative association of NFL with Alzheimer's disease (AD) indices. Relevant studies were identified after a literature search in electronic databases and study selection was based on pre-determined eligibility criteria....

journal_title：Frontiers in aging neuroscience

authors： Jin M,Cao L,Dai YP

更新日期：2019-09-13 00:00:00

abstract：:Aerobic physical exercise (APE) leads to improved brain functions. To better understand the beneficial effect of APE on the aging brain, a morphometric study was carried out of changes in hippocampal synapses of old (>27 months) Balb/c mice undergoing treadmill training (OTT) for 4 weeks in comparison with old sedenta...

journal_title：Frontiers in aging neuroscience

authors： Fattoretti P,Malatesta M,Cisterna B,Milanese C,Zancanaro C

更新日期：2018-05-16 00:00:00

abstract：:Exercise may be the most commonly offered yet least consistently followed therapeutic advice for people with Parkinson's disease (PD). Epidemiological studies of prospectively followed cohorts have shown a lower risk for later developing PD in healthy people who report moderate to high levels of physical activity, and...

journal_title：Frontiers in aging neuroscience

authors： Crotty GF,Schwarzschild MA

更新日期：2020-06-19 00:00:00

abstract：:The enteric nervous system (ENS) poses the intrinsic innervation of the gastrointestinal tract and plays a critical role for all stages of postnatal life. There is increasing scientific and clinical interest in acquired or age-related gastrointestinal dysfunctions that can be manifested in diseases such as gut constip...

journal_title：Frontiers in aging neuroscience

authors： Hetz S,Acikgoez A,Moll C,Jahnke HG,Robitzki AA,Metzger R,Metzger M

更新日期：2014-10-15 00:00:00

abstract：:Memory encoding and retrieval problems are inherent to aging. To date, however, the effect of aging upon the neural correlates of forming memory traces remains poorly understood. Resting-state fMRI connectivity can be used to investigate initial consolidation. We compared within and between network connectivity differ...

journal_title：Frontiers in aging neuroscience

authors： Jacobs HI,Dillen KN,Risius O,Göreci Y,Onur OA,Fink GR,Kukolja J

更新日期：2015-01-09 00:00:00

abstract：:Background: Cognitive frailty (CF) is defined as the simultaneous presence of physical frailty and cognitive impairment among older adults without dementia. Previous studies have revealed that neuropathological changes may contribute to the degeneration of subcortical nuclei in the process of cognitive impairment. How...

journal_title：Frontiers in aging neuroscience

authors： Wan M,Xia R,Lin H,Qiu P,He J,Ye Y,Tao J,Chen L,Zheng G

更新日期：2020-07-28 00:00:00

abstract：:Aging is related to a deterioration of cognitive performance and to multiple alterations in the brain. Even before the beginning of a noticeable cognitive decline, the framework which holds cognitive function experiences these alterations. From a system-vulnerability point of view of cognition, the deterioration assoc...

journal_title：Frontiers in aging neuroscience

authors： Roldán-Tapia MD,Cánovas R,León I,García-Garcia J

更新日期：2017-10-24 00:00:00

abstract：:Objective: Cerebral small vessel disease (SVD) is associated with increased mortality, disability and cognitive decline, depression in stroke survivors. This study examined the association between SVD burden, defined by a combination of SVD markers, and health-related quality of life (HRQoL) in acute ischemic stroke. ...

journal_title：Frontiers in aging neuroscience

authors： Liang Y,Chen YK,Deng M,Mok VCT,Wang DF,Ungvari GS,Chu CW,Kamiya A,Tang WK

更新日期：2017-11-13 00:00:00

abstract：:Previous studies have showed that spatial memory declines with age but have not clarified the relevance of different landmark cues for specifying heading directions among different age groups. This study examined differences between younger, middle-aged and older adults in route learning and memory tasks after they na...

journal_title：Frontiers in aging neuroscience

authors： Zhong JY,Moffat SD

更新日期：2016-05-27 00:00:00

abstract：:Individuals with Parkinson's disease (PD) mainly suffer from motor impairments which increase the risk of falls and lead to a decline of quality of life. Several studies investigated the long-term effect of dance for people with PD. The aims of the present study were to investigate (i) the short-term effects of dance ...

journal_title：Frontiers in aging neuroscience

authors： Heiberger L,Maurer C,Amtage F,Mendez-Balbuena I,Schulte-Mönting J,Hepp-Reymond MC,Kristeva R

更新日期：2011-10-10 00:00:00

abstract：:Background and Purpose: Previous studies of voxel-based morphometry (VBM) have found that patients with type 2 diabetes mellitus (T2DM) exhibit gray matter alterations, but these findings are inconsistent and have not been quantitatively reviewed. Therefore, the aim of this study was to conduct a quantitative meta-ana...

journal_title：Frontiers in aging neuroscience

authors： Liu J,Liu T,Wang W,Ma L,Ma X,Shi S,Gong Q,Wang M

更新日期：2017-05-22 00:00:00

abstract：:The emotions evoked by music can enhance recognition of excerpts. It has been suggested that memory is better for high than for low arousing music (Eschrich et al., 2005; Samson et al., 2009), but it remains unclear whether positively (Eschrich et al., 2008) or negatively valenced music (Aubé et al., 2013; Vieillard a...

journal_title：Frontiers in aging neuroscience

authors： Alonso I,Dellacherie D,Samson S

更新日期：2015-03-12 00:00:00

abstract：:Neurons with histopathological changes consistent with granulovacuolar degeneration (GVD) were found in brain sections from aged cynomolgus monkeys (Macaca fascicularis) with clinical and pathological signs of cognitive aging. To our knowledge, this is the first reported description of GVD in non-human primates. GVD-l...

journal_title：Frontiers in aging neuroscience

authors： Darusman HS,Agungpriyono DR,Kusumaputri VA,Sajuthi D,Schapiro SJ,Hau J

更新日期：2019-03-07 00:00:00

abstract：:Alzheimer's disease (AD) is the most common form of dementia worldwide. It is mostly known for its devastating effect on memory and learning but behavioral alterations commonly known as neuropsychiatric disturbances (NPDs) are also characteristics of the disease. These include apathy, depression-like behavior, and sle...

journal_title：Frontiers in aging neuroscience

authors： Clement A,Wiborg O,Asuni AA

更新日期：2020-03-06 00:00:00

abstract：:Studies of the neural mechanisms of navigation and context discrimination have generated a powerful heuristic for understanding how neural codes, circuits, and computations contribute to accurate behavior as animals traverse and learn about spatially extended environments. It is assumed that memories are updated as a ...

journal_title：Frontiers in aging neuroscience

authors： Penner MR,Mizumori SJ

更新日期：2012-08-08 00:00:00

abstract：:Background: Smart Aging is a Serious games (SGs) platform in a 3D virtual environment in which users perform a set of screening tests that address various cognitive skills. The tests are structured as 5 tasks of activities of daily life in a familiar environment. The main goal of the present study is to compare a cogn...

journal_title：Frontiers in aging neuroscience

authors： Bottiroli S,Tassorelli C,Lamonica M,Zucchella C,Cavallini E,Bernini S,Sinforiani E,Pazzi S,Cristiani P,Vecchi T,Tost D,Sandrini G

更新日期：2017-11-21 00:00:00

abstract：:Alzheimer's disease (AD) is marked by the presence of amyloid beta (Aβ) plaques, neurofibrillary tangles (NFT), neuronal death and synaptic loss, and inflammation in the brain. AD research has, in large part, been dedicated to the understanding of Aβ and NFT deposition as well as to the pharmacological reduction of th...

journal_title：Frontiers in aging neuroscience

authors： Frost GR,Jonas LA,Li YM

更新日期：2019-12-10 00:00:00

abstract：:The network activated during normal route learning shares considerable homology with the network of degeneration in the earliest symptomatic stages of Alzheimer's disease (AD). This inspired the virtual route learning test (VRLT) in which patients learn routes in a virtual reality environment. This study investigated ...

journal_title：Frontiers in aging neuroscience

authors： Pengas G,Williams GB,Acosta-Cabronero J,Ash TW,Hong YT,Izquierdo-Garcia D,Fryer TD,Hodges JR,Nestor PJ

更新日期：2012-07-04 00:00:00

abstract：:Alzheimer's disease (AD) is a neurodegenerative disorder associated with the progressive dysfunction of cognitive ability. Previous research has indicated that the default mode network (DMN) is closely related to cognition and is impaired in Alzheimer's disease. Because recent studies have shown that different frequen...

journal_title：Frontiers in aging neuroscience

authors： Li Y,Yao H,Lin P,Zheng L,Li C,Zhou B,Wang P,Zhang Z,Wang L,An N,Wang J,Zhang X

更新日期：2017-08-03 00:00:00

abstract：:Objectives: To explore the transfer effects of cognitive training on working memory among older Chinese adults with mild cognitive impairment (MCI). Methods: Sixty-two MCI participants aged more than 60 years old were recruited by holding recruitment sessions in communities in China [33 for cognitive training, and 29 ...

journal_title：Frontiers in aging neuroscience

authors： Weng W,Liang J,Xue J,Zhu T,Jiang Y,Wang J,Chen S

更新日期：2019-08-14 00:00:00

abstract：:Background: Although obesity and physical activity influence psychosocial well-being, these effects may vary based on race, gender, and their intersection. Using 6-year follow-up data of a nationally representative sample of adults over age of 50 in the United States, this study aimed to explore race by gender differe...

journal_title：Frontiers in aging neuroscience

authors： Carter JD,Assari S

更新日期：2017-01-04 00:00:00