Regulation of Chromatin Structure During Neural Development.

abstract：:Introduction: Spasticity is a typical motor disorder in patients affected by stroke. Typically post-stroke rehabilitation consists of repetition of mobilization exercises on impaired limbs, aimed to reduce muscle hypertonia and mitigate spastic reflexes. It is currently strongly debated if the treatment's effectivenes...

journal_title：Frontiers in neuroscience

authors： Crea S,Cempini M,Mazzoleni S,Carrozza MC,Posteraro F,Vitiello N

更新日期：2017-05-12 00:00:00

abstract：:Alzheimer's disease (AD) is a progressive brain disorder with gradual memory loss that correlates to cognitive deficits in the elderly population. Recent studies have shown the potentials of machine learning algorithms to identify biomarkers and functional brain activity patterns across various AD stages using electro...

journal_title：Frontiers in neuroscience

authors： Fan M,Yang AC,Fuh JL,Chou CA

更新日期：2018-10-04 00:00:00

abstract：:Ablation of adult neurogenesis in mice has revealed that young adult-born granule cells (abGCs) are required for some of the behavioral responses to antidepressants (ADs), yet the mechanism by which abGCs contribute to AD action remains unknown. During their maturation process, these immature neurons exhibit unique pr...

journal_title：Frontiers in neuroscience

authors： Tannenholz L,Hen R,Kheirbek MA

更新日期：2016-05-31 00:00:00

abstract：:Duchenne muscular dystrophy (DMD) is a lethal X-linked muscular disease caused by defective expression of the cytoskeletal protein dystrophin (Dp427). Selected autonomic and central neurons, including retinal neurons, express Dp427 and/or dystrophin shorter isoforms. Because of this, DMD patients may also experience d...

journal_title：Frontiers in neuroscience

authors： Persiconi I,Cosmi F,Guadagno NA,Lupo G,De Stefano ME

更新日期：2020-08-31 00:00:00

abstract：:Traumatic brain injury (TBI) is a kind of severe brain injury characterized with a high incidence rate and a high disability rate. Low-intensity transcranial ultrasound stimulation (LITUS) is a promising neuroprotective method for improving the functional prognosis of TBI. The fractional anisotropy (FA) value and mean...

journal_title：Frontiers in neuroscience

authors： Zheng T,Du J,Yuan Y,Wu S,Jin Y,Wang Z,Liu D,Shi Q,Wang X,Liu L

更新日期：2020-03-10 00:00:00

abstract：:While the transient receptor potential vanilloid 1 (TRPV1) ion channel, a non-selective calcium-permeable cation channel with high Ca2+ permeability, mainly integrates physical and chemical stimuli for nociception, recent studies suggest that it has a role beyond a noxious thermal sensor. In fact, TRPV1 is presently b...

journal_title：Frontiers in neuroscience

authors： Zhang M,Ruwe D,Saffari R,Kravchenko M,Zhang W

更新日期：2020-02-07 00:00:00

abstract：:The acute phase of stroke is accompanied by functional changes in the activity and interplay of both hemispheres. In healthy subjects, gender is known to impact the functional brain organization. We investigated whether gender influences also acute stroke functional changes. In thirty-five ischemic stroke patients, we...

journal_title：Frontiers in neuroscience

authors： Di Lazzaro V,Pellegrino G,Di Pino G,Ranieri F,Lotti F,Florio L,Capone F

更新日期：2016-01-29 00:00:00

abstract：:Brain-behavior correlations are commonly used to explore the associations between the brain and human behavior in cognitive neuroscience studies. There are many critics of the correlation approach, however. Most problems associated with correlation approaches originate in the weak statistical power of traditional corr...

journal_title：Frontiers in neuroscience

authors： Zhou X,Li M,Zhou H,Li L,Cui J

更新日期：2018-11-06 00:00:00

abstract：:To ensure survival, animals must update the internal representations of their environment in a trial-and-error fashion. Psychological studies of associative learning and neurophysiological analyses of dopaminergic neurons have suggested that this updating process involves the temporal-difference (TD) method in the bas...

journal_title：Frontiers in neuroscience

authors： Wen C,Ogura Y,Matsushima T

更新日期：2016-11-08 00:00:00

abstract：:Several studies of semantic memory in non-musical domains involving recognition of items from long-term memory have shown an age-related shift from the medial temporal lobe structures to the frontal lobe. However, the effects of aging on musical semantic memory remain unexamined. We compared activation associated with...

journal_title：Frontiers in neuroscience

authors： Sikka R,Cuddy LL,Johnsrude IS,Vanstone AD

更新日期：2015-10-06 00:00:00

abstract：Background:Cochlear implants (CIs), which have been designed primarily to support spoken communication of persons with severe to profound hearing loss, are highly effective in supporting speech perception in quiet listening conditions. CI users as a group achieve significantly poorer perception and appraisal of music, ...

journal_title：Frontiers in neuroscience

authors： Gfeller K,Driscoll V,Schwalje A

更新日期：2019-11-21 00:00:00

abstract：:It is undisputed that presenting a rhythmic stimulus leads to a measurable brain response that follows the rhythmic structure of this stimulus. What is still debated, however, is the question whether this brain response exclusively reflects a regular repetition of evoked responses, or whether it also includes entraine...

journal_title：Frontiers in neuroscience

authors： Zoefel B,Ten Oever S,Sack AT

更新日期：2018-03-07 00:00:00

abstract：:Aromatase cytochrome P450arom (cyp19) is the only enzyme that has the ability to convert androgens into estrogens. Estrogens, which are produced locally in the vertebrate brain play many fundamental roles in neuroendocrine functions, reproductive functions, socio-sexual behaviors, and neurogenesis. Radial glial cells ...

journal_title：Frontiers in neuroscience

authors： Xing L,Esau C,Trudeau VL

更新日期：2016-01-12 00:00:00

abstract：:Drug addiction is a chronic disease characterized by recurring episodes of abstinence and relapse. The precise mechanisms underlying this pattern are yet to be elucidated, but stress is thought to be a major factor in relapse. Recently, we reported that rats under withdrawal and exposed to a mild chronic stressor, pro...

journal_title：Frontiers in neuroscience

authors： Sedki F,Abbas Z,Angelis S,Martin J,D'Cunha T,Shalev U

更新日期：2013-06-06 00:00:00

abstract：:The blood-brain barrier (BBB) mediates the communication between the periphery and the central nervous system (CNS). Recently, CNS insulin resistance has been elucidated to play a role in neurodegenerative disease. This has stimulated a wealth of information on the molecular impact of insulin in the brain, particularl...

journal_title：Frontiers in neuroscience

authors： Rhea EM,Banks WA

更新日期：2019-06-04 00:00:00

abstract：:While neuromorphic systems may be the ultimate platform for deploying spiking neural networks (SNNs), their distributed nature and optimization for specific types of models makes them unwieldy tools for developing them. Instead, SNN models tend to be developed and simulated on computers or clusters of computers with s...

journal_title：Frontiers in neuroscience

authors： Knight JC,Nowotny T

更新日期：2018-12-12 00:00:00

abstract：:In functional MRI (fMRI), population receptive field (pRF) models allow a quantitative description of the response as a function of the features of the stimuli that are relevant for each voxel. The most popular pRF model used in fMRI assumes a Gaussian shape in the features space (e.g., the visual field) reducing the ...

journal_title：Frontiers in neuroscience

authors： Lage-Castellanos A,Valente G,Senden M,De Martino F

更新日期：2020-07-30 00:00:00

abstract：:Persons diagnosed with disorders of consciousness (DOC) typically suffer from motor and cognitive disabilities. Recent research has shown that non-invasive brain-computer interface (BCI) technology could help assess these patients' cognitive functions and command following abilities. 20 DOC patients participated in th...

journal_title：Frontiers in neuroscience

authors： Murovec N,Heilinger A,Xu R,Ortner R,Spataro R,La Bella V,Miao Y,Jin J,Chatelle C,Laureys S,Allison BZ,Guger C

更新日期：2020-04-09 00:00:00

abstract：:The linearity and stationarity of fMRI time series need to be understood due to their important roles in the choice of approach for brain network analysis. In this paper, we investigated the stationarity and linearity of resting-state fMRI (rs-fMRI) time-series data from the Midnight Scan Club datasets. The degree of ...

journal_title：Frontiers in neuroscience

authors： Guan S,Jiang R,Bian H,Yuan J,Xu P,Meng C,Biswal B

更新日期：2020-06-11 00:00:00

abstract：:Hardware-based spiking neural networks (SNNs) inspired by a biological nervous system are regarded as an innovative computing system with very low power consumption and massively parallel operation. To train SNNs with supervision, we propose an efficient on-chip training scheme approximating backpropagation algorithm ...

journal_title：Frontiers in neuroscience

authors： Kwon D,Lim S,Bae JH,Lee ST,Kim H,Seo YT,Oh S,Kim J,Yeom K,Park BG,Lee JH

更新日期：2020-07-07 00:00:00

abstract：:In this paper we review several ways of realizing asynchronous Spike-Timing-Dependent-Plasticity (STDP) using memristors as synapses. Our focus is on how to use individual memristors to implement synaptic weight multiplications, in a way such that it is not necessary to (a) introduce global synchronization and (b) to ...

journal_title：Frontiers in neuroscience

authors： Serrano-Gotarredona T,Masquelier T,Prodromakis T,Indiveri G,Linares-Barranco B

更新日期：2013-02-18 00:00:00

abstract：:Risperidone (RIS), an atypical antipsychotic has been found to show anti-inflammatory effect against lipopolysaccharide (LPS)-induced inflammation. In vitro study has revealed that RIS inhibits the LPS-induced reactive oxygen species (ROS) formation. We investigated the antioxidant effects of RIS on LPS-induced oxidat...

journal_title：Frontiers in neuroscience

authors： Al-Amin MM,Choudhury MFR,Chowdhury AS,Chowdhury TR,Jain P,Kazi M,Alkholief M,Alshehri SM,Reza HM

更新日期：2018-06-08 00:00:00

abstract：:Movement is planned and coordinated by the brain and carried out by contracting muscles acting on specific joints. Motor commands initiated in the brain travel through descending pathways in the spinal cord to effector motor neurons before reaching target muscles. Damage to these pathways by spinal cord injury (SCI) c...

journal_title：Frontiers in neuroscience

authors： Grahn PJ,Mallory GW,Berry BM,Hachmann JT,Lobel DA,Lujan JL

更新日期：2014-09-17 00:00:00

abstract：:Gene expression profiling was performed on the human neuroglial cell line T98G after treatment with adaptogen ADAPT-232 and its constituents - extracts of Eleutherococcus senticosus root, Schisandra chinensis berry, and Rhodiola rosea root as well as several constituents individually, namely, eleutheroside E, schizand...

journal_title：Frontiers in neuroscience

authors： Panossian A,Hamm R,Kadioglu O,Wikman G,Efferth T

更新日期：2013-02-20 00:00:00

abstract：:The global prevalence of obesity has been steadily increasing. Although pharmacotherapy and bariatric surgeries can be useful adjuvants in the treatment of morbid obesity, they may lose long-term effectiveness. Obesity result largely from unbalanced energy homeostasis. Palatable and densely caloric foods may affect th...

journal_title：Frontiers in neuroscience

authors： Formolo DA,Gaspar JM,Melo HM,Eichwald T,Zepeda RJ,Latini A,Okun MS,Walz R

更新日期：2019-04-18 00:00:00

abstract：:Reconsolidation of memories has mostly been studied at the behavioral and molecular level. Here, we put forward a simple extension of existing computational models of synaptic consolidation to capture hippocampal slice experiments that have been interpreted as reconsolidation at the synaptic level. The model implement...

journal_title：Frontiers in neuroscience

authors： Kastner DB,Schwalger T,Ziegler L,Gerstner W

更新日期：2016-05-18 00:00:00

abstract：:Protein tyrosine phosphatases (PTPs) are important regulators of intracellular signaling pathways via the dephosphorylation of phosphotyrosyl residues on various receptor and non-receptor substrates. The phosphorylation state of central nervous system (CNS) signaling components underlies the molecular mechanisms of a ...

journal_title：Frontiers in neuroscience

authors： Tsou RC,Bence KK

更新日期：2013-01-07 00:00:00

abstract：:Perinatal asphyxia (PA) is a clinical condition brought by a birth temporary oxygen deprivation associated with long-term damage in the corpus striatum, one of the most compromised brain areas. Palmitoylethanolamide (PEA) is a neuromodulator well known for its protective effects in brain injury models, including PA, a...

journal_title：Frontiers in neuroscience

authors： Udovin LD,Kobiec T,Herrera MI,Toro-Urrego N,Kusnier CF,Kölliker-Frers RA,Ramos-Hryb AB,Luaces JP,Otero-Losada M,Capani F

更新日期：2020-01-08 00:00:00

abstract：:Interaural time differences (ITD) and interaural level differences (ILD) both signal horizontal sound source location. To achieve a unified percept of our acoustic environment, these two cues require integration. In the present study, we tested this integration of ITD and ILD with electroencephalography (EEG) by measu...

journal_title：Frontiers in neuroscience

authors： Altmann CF,Ueda R,Furukawa S,Kashino M,Mima T,Fukuyama H

更新日期：2017-07-06 00:00:00

abstract：:Alzheimer's disease (AD) and Parkinson's disease (PD) are the two most common neurodegenerative disorders worldwide, with age being their major risk factor. The increasing worldwide life expectancy, together with the scarcity of available treatment choices, makes it thus pressing to find the molecular basis of AD and ...

journal_title：Frontiers in neuroscience

authors： Bordone MC,Barbosa-Morais NL

更新日期：2020-12-09 00:00:00