Pharmacogenomics of Medications Commonly Used in the Intensive Care Unit.

Abstract:

:In the intensive care unit (ICU) setting, where highly variable and insufficient drug efficacies, as well as frequent and unpredictable adverse drug reactions (ADRs) occur, pharmacogenomics (PGx) offers an opportunity to improve health outcomes. However, PGx has not been fully evaluated in the ICU, partly due to lack of knowledge of how genetic markers may affect drug therapy. To fill in this gap, we conducted a review to summarize the PGx information for the medications commonly encountered in the ICU.

journal_name

Front Pharmacol

authors

Zhou S,Skaar DJ,Jacobson PA,Huang RS

doi

10.3389/fphar.2018.01436

subject

Has Abstract

pub_date

2018-12-04 00:00:00

pages

1436

issn

1663-9812

journal_volume

9

pub_type

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