Ten Years of Tau-Targeted Immunotherapy: The Path Walked and the Roads Ahead.

abstract：:The sliding-window-based dynamic functional connectivity networks (D-FCNs) derived from resting-state functional magnetic resonance imaging (rs-fMRI) are effective methods for diagnosing various neurological diseases, including autism spectrum disorder (ASD). However, traditional D-FCNs are low-order networks based on...

journal_title：Frontiers in neuroscience

authors： Zhao F,Chen Z,Rekik I,Lee SW,Shen D

更新日期：2020-04-28 00:00:00

abstract：:Comorbid depressive disorders confound the diagnosis and therapy of schizophrenia. Using a murine model incorporating both MK801 and chronic unpredictable mild stress exposures, we successfully replicated both psychosis and depression. Ex vivo patch clamp recordings and in vivo calcium imaging demonstrated impaired ne...

journal_title：Frontiers in neuroscience

authors： Zhou C,Kong D,Xue R,Chen M,Li G,Xu Y,Liu S,Tian H,Zhuo C

更新日期：2020-06-03 00:00:00

abstract：:Resting-state functional magnetic resonance imaging (rs-fMRI) is a widely used technique for mapping the brain's functional architecture, so delineating the main sources of variance comprising the signal is crucial. Low frequency oscillations (LFO) that are not of neural origin, but which are driven by mechanisms rela...

journal_title：Frontiers in neuroscience

authors： Whittaker JR,Driver ID,Venzi M,Bright MG,Murphy K

更新日期：2019-05-07 00:00:00

abstract：:The recently renewed focus on the human exploration of outer space has boosted the interest toward a variety of questions regarding health of astronauts and cosmonauts. Among the others, sleep has traditionally been considered a central issue. To extend the research chances, human sleep alterations have been investiga...

journal_title：Frontiers in neuroscience

authors： Zivi P,De Gennaro L,Ferlazzo F

更新日期：2020-08-11 00:00:00

abstract：:Understanding the complex neural mechanisms controlling urinary bladder activity is an extremely important topic in both neuroscience and urology. Simultaneously recording of the bladder activity and neural activity in related brain regions will largely advance this field. However, such recording approach has long bee...

journal_title：Frontiers in neuroscience

authors： Yao J,Li Q,Li X,Qin H,Liang S,Liao X,Chen X,Li W,Yan J

更新日期：2019-06-25 00:00:00

abstract：:Recent neuroimaging studies in primates aim to define the functional properties of auditory cortical areas, especially areas beyond A1, in order to further our understanding of the auditory cortical organization. Precise mapping of functional magnetic resonance imaging (fMRI) results and interpretation of their locali...

journal_title：Frontiers in neuroscience

authors： Joly O,Baumann S,Balezeau F,Thiele A,Griffiths TD

更新日期：2014-07-21 00:00:00

abstract：:Neurons are generated during embryonic development and in adulthood, although adult neurogenesis is restricted to two main brain regions, the hippocampus and olfactory bulb. The subventricular zone (SVZ) of the lateral ventricles generates neural stem/progenitor cells that continually provide the olfactory bulb (OB) w...

journal_title：Frontiers in neuroscience

authors： Figueres-Oñate M,López-Mascaraque L

更新日期：2016-05-09 00:00:00

abstract：:Studies of delay discounting typically have involved choices between smaller, immediate outcomes and larger, delayed outcomes. In a study of delay discounting in humans, Green et al. (2005) added a period of time prior to both outcomes, creating a delay common to both. They found that the subjective value of the more ...

journal_title：Frontiers in neuroscience

authors： Calvert AL,Green L,Myerson J

更新日期：2011-08-17 00:00:00

abstract：:Blood-brain barrier opening (BBBO) with pulsed Focused Ultrasound (pFUS) and microbubbles (MB) has received increasing interest as a method for neurotherapeutics of the central nervous system. In general, conventional MRI [i.e., T2w, T2∗w, gadolinium (Gd) enhanced T1w] is used to monitor the effects of pFUS+MB on BBBO...

journal_title：Frontiers in neuroscience

authors： Tu TW,Kovacs ZI,Sundby M,Witko JA,Papadakis GZ,Reid WC,Hammoud DA,Frank JA

更新日期：2020-08-25 00:00:00

abstract：:While brain stimulation techniques have been examined as treatment options for chronic tinnitus for many years, they have recently been extended to multimodal treatment approaches. As chronic tinnitus is often accompanied by comorbid muscular tension in the neck and back, we performed a one-arm pilot study to explore ...

journal_title：Frontiers in neuroscience

authors： Vielsmeier V,Schecklmann M,Schlee W,Kreuzer PM,Poeppl TB,Rupprecht R,Langguth B,Lehner A

更新日期：2018-02-20 00:00:00

abstract：:Transcranial direct current stimulation (tDCS) is a non-invasive brain stimulation technique to change cortical excitability. Its effects are shown for cognitive processing, and behavior in the motor and perceptual domains. However, evidence of tDCS effects in the perceptual domain particularly for auditory processing...

journal_title：Frontiers in neuroscience

authors： Kunzelmann K,Meier L,Grieder M,Morishima Y,Dierks T

更新日期：2018-11-27 00:00:00

abstract：:Psychiatric disorders represent a great medical and social challenge and people suffering from these conditions face many impairments regarding personal and professional life. In addition, a mental disorder will manifest itself in approximately one quarter of the world's population at some period of their life. Dysfun...

journal_title：Frontiers in neuroscience

authors： Zuccoli GS,Saia-Cereda VM,Nascimento JM,Martins-de-Souza D

更新日期：2017-09-07 00:00:00

abstract：:The analysis of spontaneous functional connectivity (sFC) reveals the statistical connections between regions of the brain consistent with underlying functional communication networks within the brain. In this work, we describe the implementation of a complete all-to-all network analysis of resting state neuronal acti...

journal_title：Frontiers in neuroscience

authors： Schmidt BT,Ghuman AS,Huppert TJ

更新日期：2014-06-11 00:00:00

abstract：:Although, cochlear implants (CI) traditionally have been used to treat individuals with bilateral profound sensorineural hearing loss, a recent trend is to implant individuals with residual low-frequency hearing. Notably, many of these individuals demonstrate an air-bone gap (ABG) in low-frequency, pure-tone threshold...

journal_title：Frontiers in neuroscience

authors： Koka K,Saoji AA,Attias J,Litvak LM

更新日期：2017-04-18 00:00:00

abstract：:In this paper, we present an alternative approach to perform spike sorting of complex brain signals based on spiking neural networks (SNN). The proposed architecture is suitable for hardware implementation by using resistive random access memory (RRAM) technology for the implementation of synapses whose low latency (<...

journal_title：Frontiers in neuroscience

authors： Werner T,Vianello E,Bichler O,Garbin D,Cattaert D,Yvert B,De Salvo B,Perniola L

更新日期：2016-11-03 00:00:00

abstract：:Oxylipins are a series of bioactive lipid metabolites derived from polyunsaturated fatty acids that are involved in cerebral homeostasis and the development of intracerebral hemorrhage (ICH). However, comprehensive quantification of the oxylipin profile in ICH remains unknown. Therefore, an ICH mouse model was constru...

journal_title：Frontiers in neuroscience

authors： Yuan JJ,Chen Q,Xiong XY,Zhang Q,Xie Q,Huang JC,Yang GQ,Gong CX,Qiu ZM,Sang HF,Zi WJ,He Q,Xu R,Yang QW

更新日期：2020-09-23 00:00:00

abstract：:Electroencephalography (EEG) is perhaps the most widely used brain-imaging technique for pediatric populations. However, EEG signals are prone to distortion by motion. Compared to adults, infants' motion is both more frequent and less stereotypical yet motion effects on the infant EEG signal are largely undocumented. ...

journal_title：Frontiers in neuroscience

authors： Georgieva S,Lester S,Noreika V,Yilmaz MN,Wass S,Leong V

更新日期：2020-04-28 00:00:00

abstract：:Funding institutions and researchers increasingly expect that data will be shared to increase scientific integrity and provide other scientists with the opportunity to use the data with novel methods that may advance understanding in a particular field of study. In practice, sharing human subject data can be complicat...

journal_title：Frontiers in neuroscience

authors： Song X,Wang J,Wang A,Meng Q,Prescott C,Tsu L,Eckert MA

更新日期：2015-09-22 00:00:00

abstract：:In this work, we propose a Spiking Neural Network (SNN) consisting of input neurons sparsely connected by plastic synapses to a randomly interlinked liquid, referred to as Liquid-SNN, for unsupervised speech and image recognition. We adapt the strength of the synapses interconnecting the input and liquid using Spike T...

journal_title：Frontiers in neuroscience

authors： Srinivasan G,Panda P,Roy K

更新日期：2018-08-23 00:00:00

abstract：:We present a spiking neural network model of the thalamic Lateral Geniculate Nucleus (LGN) developed on SpiNNaker, which is a state-of-the-art digital neuromorphic hardware built with very-low-power ARM processors. The parallel, event-based data processing in SpiNNaker makes it viable for building massively parallel n...

journal_title：Frontiers in neuroscience

authors： Sen-Bhattacharya B,Serrano-Gotarredona T,Balassa L,Bhattacharya A,Stokes AB,Rowley A,Sugiarto I,Furber S

更新日期：2017-08-09 00:00:00

abstract：:Induction of lordosis as typical female sexual behavior in rodents is dependent on a mount stimulus from males and blood levels of estrogen. Periaqueductal gray (PAG) efferent neurons have been suggested to be important for lordosis behavior; however, the neurochemical basis remains to be understood. In this study, we...

journal_title：Frontiers in neuroscience

authors： Yamada S,Kawata M

更新日期：2014-12-18 00:00:00

abstract：:Abdominal obesity is important for understanding obesity, which is a worldwide medical problem. We explored structural and functional brain differences in people with abdominal and non-abdominal obesity by using multimodal neuroimaging and up-to-date analysis methods. A total of 274 overweight people, whose body mass ...

journal_title：Frontiers in neuroscience

authors： Park BY,Lee MJ,Kim M,Kim SH,Park H

更新日期：2018-10-11 00:00:00

abstract：:With emerging evidence showing a wide distribution of secretin (SCT) and its receptor (SCTR) in the central nervous system (CNS), the putative neuropeptide role of SCT has become more appreciated since the disruption of SCT/SCTR axis affects various neural functions. This mini review thus focuses on the effects of SCT...

journal_title：Frontiers in neuroscience

authors： Wang L,Zhang L

更新日期：2020-05-06 00:00:00

abstract：:Exposure in vivo (EXP) is a cognitive-behavioral treatment aimed at reducing pain-related fear in chronic pain, and has proven successful in reducing pain-related disability in patients with chronic low back pain (cLBP). The current longitudinal study aimed to reveal the neural correlates of changes in pain-related fe...

journal_title：Frontiers in neuroscience

authors： Timmers I,de Jong JR,Goossens M,Verbunt JA,Smeets RJ,Kaas AL

更新日期：2019-09-17 00:00:00

abstract：:Kolmer-Agduhr (KA) cells are a subgroup of interneurons positioned adjacent to the neurocoele with cilia on the apical surface protruding into the central canal of the spinal cord. Although KA cells were identified almost a century ago, their development and functions are only beginning to be unfolded. Recent studies ...

journal_title：Frontiers in neuroscience

authors： Yang L,Wang F,Strähle U

更新日期：2020-10-09 00:00:00

abstract：:Growing evidence indicates that neuropathic pain is frequently accompanied by cognitive impairments, which aggravate the quality of life of chronic pain patients. Here, we investigated whether acupuncture treatments can improve cognitive dysfunction as well as allodynia induced by neuropathic pain in mice. One week af...

journal_title：Frontiers in neuroscience

authors： Jang JH,Kim YK,Jung WM,Kim HK,Song EM,Kim HY,Oh JY,Park JY,Ryu Y,Song MY,Park HJ

更新日期：2019-09-20 00:00:00

abstract：:There are few behavioral effects as ubiquitous as the speed-accuracy tradeoff (SAT). From insects to rodents to primates, the tendency for decision speed to covary with decision accuracy seems an inescapable property of choice behavior. Recently, the SAT has received renewed interest, as neuroscience approaches begin ...

journal_title：Frontiers in neuroscience

authors： Heitz RP

更新日期：2014-06-11 00:00:00

abstract：:Risperidone (RIS), an atypical antipsychotic has been found to show anti-inflammatory effect against lipopolysaccharide (LPS)-induced inflammation. In vitro study has revealed that RIS inhibits the LPS-induced reactive oxygen species (ROS) formation. We investigated the antioxidant effects of RIS on LPS-induced oxidat...

journal_title：Frontiers in neuroscience

authors： Al-Amin MM,Choudhury MFR,Chowdhury AS,Chowdhury TR,Jain P,Kazi M,Alkholief M,Alshehri SM,Reza HM

更新日期：2018-06-08 00:00:00

abstract：Background:Postherpetic neuralgia (PHN) is a form of long-lasting neuropathic pain that can severely affect patients' quality of life. Pulsed radiofrequency (PRF) has been proven to be effective in treating PHN, but the optimal radiofrequency parameters are still not well defined. This retrospective study aimed to comp...

journal_title：Frontiers in neuroscience

authors： Han Z,Hong T,Ding Y,Wang S,Yao P

更新日期：2020-12-18 00:00:00

abstract：:The neuropeptide oxytocin plays a central role in prosocial and parental behavior in non-human mammals as well as humans. It has been suggested that oxytocin may affect visual processing of infant faces and emotional reaction to infants. Healthy male volunteers (N = 13) were tested for their ability to detect infant o...

journal_title：Frontiers in neuroscience

authors： Saito A,Hamada H,Kikusui T,Mogi K,Nagasawa M,Mitsui S,Higuchi T,Hasegawa T,Hiraki K

更新日期：2014-07-29 00:00:00