Measuring Habitual Arm Use Post-stroke With a Bilateral Time-Constrained Reaching Task.

abstract：:Objectives: This study aimed to assess the efficacy of minocycline for the treatment of acute ischemic stroke. Background: While there have been meta-analysis that surveyed the efficacy of minocycline in the treatment of acute stroke, they have some methodological limitations. We performed a new systematic review whic...

journal_title：Frontiers in neurology

authors： Sheng Z,Liu Y,Li H,Zheng W,Xia B,Zhang X,Yong VW,Xue M

更新日期：2018-12-20 00:00:00

abstract：:Background: Early imaging-based treatment response assessment of brain metastases following stereotactic radiosurgery (SRS) remains challenging. The aim of this study is to determine whether early (within 12 weeks) intratumoral changes in interstitial fluid pressure (IFP) and velocity (IFV) estimated from computationa...

journal_title：Frontiers in neurology

authors： Swinburne N,LoCastro E,Paudyal R,Oh JH,Taunk NK,Shah A,Beal K,Vachha B,Young RJ,Holodny AI,Shukla-Dave A,Hatzoglou V

更新日期：2020-05-28 00:00:00

abstract：:Background: Most travelers experience Jet Lag Disorder (JLD) symptoms due to misalignment of their circadian rhythms with respect to the new time zone. We assessed the efficacy and safety of tasimelteon (HETLIOZ®) in healthy participants using a laboratory model of JLD induced by an 8-h phase advance of the sleep-wake...

journal_title：Frontiers in neurology

authors： Polymeropoulos CM,Mohrman MA,Keefe MS,Brzezynski JL,Wang J,Prokosch LS,Polymeropoulos VM,Xiao C,Birznieks G,Polymeropoulos MH

更新日期：2020-07-09 00:00:00

abstract：:Background: Agoraphobia was described in 1871 as a condition of fear-related alterations in spatial orientation and locomotor control triggered by places or situations that might cause a patient to panic and feel trapped. In contemporary nosology, however, this original concept of agoraphobia was split into two diagno...

journal_title：Frontiers in neurology

authors： Indovina I,Conti A,Lacquaniti F,Staab JP,Passamonti L,Toschi N

更新日期：2019-08-13 00:00:00

abstract：:The sensorimotor transformations performed by central vestibular neurons constantly adapt as the animal faces conflicting sensory information or sustains injuries. To ensure the homeostasis of vestibular-related functions, neural changes could in part rely on the regulation of 2° VN intrinsic properties. Here we revie...

journal_title：Frontiers in neurology

authors： Beraneck M,Idoux E

更新日期：2012-02-28 00:00:00

abstract：:Here, we describe a 79-year-old man, admitted to our unit for worsening diplopia and fatigue, started a few weeks after an episode of bronchitis and flu vaccination. Past medical history includes myasthenia gravis (MG), well-controlled by Pyridostigmine, Azathioprine, and Prednisone. During the first days, the patient...

journal_title：Frontiers in neurology

authors： Brusa R,Faravelli I,Gagliardi D,Magri F,Cogiamanian F,Saccomanno D,Cinnante C,Mauri E,Abati E,Bresolin N,Corti S,Comi GP

更新日期：2019-08-13 00:00:00

abstract：:Background: Studies have investigated the lipid profile in amyotrophic lateral sclerosis (ALS), including the levels of total cholesterol (TC), triglyceride (TG), high-density lipoprotein (HDL), and higher low-density lipoprotein (LDL), and the associations with mortality of ALS, but the results were inconsistent. The...

journal_title：Frontiers in neurology

authors： Liu J,Luo X,Chen X,Shang H

更新日期：2020-10-15 00:00:00

abstract：:Microglia are activated during pathological events in the brain and are capable of releasing various types of inflammatory cytokines. Here, we demonstrate that the addition of 5% microglia activated by 1 μg/ml lipopolysaccharides (LPS) to hippocampal cultures upregulates Na(+) current densities (INavD) of bipolar as w...

journal_title：Frontiers in neurology

authors： Klapal L,Igelhorst BA,Dietzel-Meyer ID

更新日期：2016-03-30 00:00:00

abstract：:Magnetic resonance imaging (MRI) is a non-destructive technique that is capable of localizing pathologies and assessing other anatomical features (e.g., tissue volume, microstructure, and white matter connectivity) in postmortem, ex vivo human brains. However, when brains are removed from the skull and cerebrospinal f...

journal_title：Frontiers in neurology

authors： Shatil AS,Matsuda KM,Figley CR

更新日期：2016-11-29 00:00:00

abstract：:Traumatic brain injury (TBI) is understood as an interplay between the initial injury, subsequent secondary injuries, and a complex host response all of which are highly heterogeneous. An understanding of the underlying biology suggests a number of windows where mechanistically inspired interventions could be targeted...

journal_title：Frontiers in neurology

authors： Ercole A,Magnoni S,Vegliante G,Pastorelli R,Surmacki J,Bohndiek SE,Zanier ER

更新日期：2017-08-30 00:00:00

abstract：:Background: Tract-based spatial statistics (TBSS) is suitable for the assessment of voxel-wise changes in fiber integrity in WM tracts in the entire brain. Longitudinal TBSS analyses of early multiple sclerosis (MS) using 3 Tesla magnetic resonance imaging (MRI) are not common. Objective: To characterize microstructur...

journal_title：Frontiers in neurology

authors： Schneider R,Genç E,Ahlborn C,Gold R,Lukas C,Bellenberg B

更新日期：2019-11-05 00:00:00

abstract：:The vestibular system plays a crucial role in maintaining postural balance. Unilateral vestibular lesions result in a typical syndrome characterized by postural imbalance, altered locomotor patterns and gaze stabilization, as well as cognitive and neurovegetative disorders. One of the main difficulties encountered in ...

journal_title：Frontiers in neurology

authors： Marouane E,Rastoldo G,El Mahmoudi N,Péricat D,Chabbert C,Artzner V,Tighilet B

更新日期：2020-05-29 00:00:00

abstract：OBJECTIVE:To provide a systematic review of the clinical and radiological features of lesion-induced central positional nystagmus (CPN) and identify salient characteristics that differentiate central from peripheral positional nystagmus (PN). METHODS:Systematic literature search according to the preferred reporting it...

journal_title：Frontiers in neurology

authors： Macdonald NK,Kaski D,Saman Y,Al-Shaikh Sulaiman A,Anwer A,Bamiou DE

更新日期：2017-04-20 00:00:00

abstract：:Background: Ischemic stroke patients show alterations in peripheral leukocyte counts that may result from the sterile inflammation response as well as the occurrence of early infections. We here aimed to determine whether alterations of circulating leukocytes in acute ischemic stroke are associated with long-term func...

journal_title：Frontiers in neurology

authors： Semerano A,Strambo D,Martino G,Comi G,Filippi M,Roveri L,Bacigaluppi M

更新日期：2020-04-03 00:00:00

abstract：:Surface electromyography (sEMG) is a widely used technology in rehabilitation research and provides quantifiable information on the myoelectric output of a muscle. In this perspective, we discuss the barriers which have restricted the wide-spread use of sEMG in clinical rehabilitation of individuals with spinal cord i...

journal_title：Frontiers in neurology

authors： Pilkar R,Momeni K,Ramanujam A,Ravi M,Garbarini E,Forrest GF

更新日期：2020-12-18 00:00:00

abstract：:Daith piercing is an ear piercing located at the crus of the helix, bilaterally. It is getting great consent on social media as alternative treatment in chronic migraine. No data about its efficacy and action are available in scientific literature so far. We present the case of a 54-year-old male patient suffering fro...

journal_title：Frontiers in neurology

authors： Cascio Rizzo A,Paolucci M,Altavilla R,Brunelli N,Assenza F,Altamura C,Vernieri F

更新日期：2017-11-27 00:00:00

abstract：:Neuropathological features in Alzheimer's disease (AD) are amyloid β (Aβ) deposits and neurofibrillary changes. AD is characterized by memory impairment and cognitive dysfunction, with some reports associating these impairments with hyperexcitability caused by Aβ in the medial temporal lobe. Epileptic seizures are kno...

journal_title：Frontiers in neurology

authors： Hirokawa Y,Fujimoto A,Ichikawa N,Sato K,Tanaka T,Enoki H,Otsuki Y,Okanishi T

更新日期：2019-06-12 00:00:00

abstract：:Major advances in neonatal care have led to significant improvements in survival rates for preterm infants, but this occurs at a cost, with a strong causal link between preterm birth and neurological deficits, including cerebral palsy (CP). Indeed, in high-income countries, up to 50% of children with CP were born pret...

journal_title：Frontiers in neurology

authors： Li J,McDonald CA,Fahey MC,Jenkin G,Miller SL

更新日期：2014-10-09 00:00:00

abstract：:Tau accumulation is a prominent feature in a variety of neurodegenerative disorders and remarkable effort has been expended working out the biochemistry and cell biology of this cytoplasmic protein. Tau's wayward properties may derive from germline mutations in the case of frontotemporal lobar degeneration (FTLD-MAPT)...

journal_title：Frontiers in neurology

authors： Kang SG,Eskandari-Sedighi G,Hromadkova L,Safar JG,Westaway D

更新日期：2020-11-12 00:00:00

abstract：:Inconsistent gender differences in the outcome of TBI have been reported. The mechanism is unknown. In a recent male animal study, repeated stress followed by TBI had synergistic effects on brain gene expression and caused greater behavioral deficits. Because females are more likely to develop anxiety after stress and...

journal_title：Frontiers in neurology

authors： Xing G,Carlton J,Jiang X,Wen J,Jia M,Li H

更新日期：2014-08-28 00:00:00

abstract：PURPOSE:Traumatic brain injury involving loss of consciousness has focal effects in the human brainstem, suggesting that it may have particular consequences for eye movement control. This hypothesis was investigated by measurements of vergence eye movement parameters. METHODS:Disparity vergence eye movements were meas...

journal_title：Frontiers in neurology

authors： Tyler CW,Likova LT,Mineff KN,Elsaid AM,Nicholas SC

更新日期：2015-02-03 00:00:00

abstract：:Autism Spectrum Disorders comprise conditions that may affect cognitive development, motor skills, social interaction, communication, and behavior. This set of functional deficits often results in lack of independence for the diagnosed individuals, and severe distress for patients, families, and caregivers. There is a...

journal_title：Frontiers in neurology

authors： Fleury-Teixeira P,Caixeta FV,Ramires da Silva LC,Brasil-Neto JP,Malcher-Lopes R

更新日期：2019-10-31 00:00:00

abstract：:Functional connectivity maps using resting-state functional magnetic resonance imaging (rs-fMRI) can closely resemble task fMRI activation patterns, suggesting that resting-state brain activity may predict task-evoked activation or behavioral performance. However, this conclusion was mostly drawn upon a healthy popula...

journal_title：Frontiers in neurology

authors： Hu J,Du J,Xu Q,Yang F,Zeng F,Dai XJ,Liu X,Lu G,Zhang Z

更新日期：2017-07-19 00:00:00

abstract：:α-synuclein is involved in the pathogenesis of multiple system atrophy (MSA) and can be regulated by peripheral immune activation (PIA). We aimed to clarify the correlations between PIA and the prevalence of MSA and to analyze the role of PIA in the progression of the disease. A total of 321 patients with probable MSA...

journal_title：Frontiers in neurology

authors： Cao B,Chen X,Zhang L,Wei Q,Liu H,Feng W,Chen Y,Shang H

更新日期：2020-07-07 00:00:00

abstract：:Glaucoma is a multifactorial syndrome in which the development of pro-apoptotic signals are the causes for retinal ganglion cell (RGC) loss. Most of the research progress in the glaucoma field have been based on experimentally inducible glaucoma animal models, which provided results about RGC loss after either the cra...

journal_title：Frontiers in neurology

authors： Tirendi S,Saccà SC,Vernazza S,Traverso C,Bassi AM,Izzotti A

更新日期：2020-12-01 00:00:00

abstract：:Background: Previous studies conflicted in the association between intracranial atherosclerotic stenosis (ICAS) and the severity of white matter changes (WMC). Aims: We aimed to investigate the relationships between the severity of luminal stenosis and the hemodynamic significance of middle cerebral artery (MCA) steno...

journal_title：Frontiers in neurology

authors： Fang H,Leng X,Pu Y,Zou X,Pan Y,Song B,Soo YOY,Leung TWH,Wang C,Zhao X,Wang Y,Wang Y,Wong KS,Liu L,Xu Y,CICAS Study Group.

更新日期：2020-04-15 00:00:00

abstract：:Introduction: Symptoms following a mild traumatic brain injury (mTBI) usually resolve quickly but may persist past 3 months in up to 15% of children. Mechanisms of mTBI recovery are poorly understood, but may involve alterations in cortical neurophysiology. Transcranial Magnetic Stimulation (TMS) can non-invasively in...

journal_title：Frontiers in neurology

authors： King R,Kirton A,Zewdie E,Seeger TA,Ciechanski P,Barlow KM

更新日期：2019-05-17 00:00:00

abstract：:Quantitative mapping of the magnetic susceptibility and the effective transverse relaxation rate (R2*) are suitable to assess the iron content in distinct brain regions. In this prospective, explorative study the iron accumulation in deep gray matter nuclei (DGM) in myotonic dystrophy type 1 (DM1) and 2 (DM2) and its ...

journal_title：Frontiers in neurology

authors： Ates S,Deistung A,Schneider R,Prehn C,Lukas C,Reichenbach JR,Schneider-Gold C,Bellenberg B

更新日期：2019-12-13 00:00:00

abstract：:Traumatic brain injury (TBI) is a major health concern worldwide. Laboratory studies utilizing animal models of TBI are essential for addressing pathological mechanisms of brain injury and development of innovative treatments. Over the past 75 years, pioneering head injury researchers have devised and tested a number ...

journal_title：Frontiers in neurology

authors： Lyeth BG

更新日期：2016-12-02 00:00:00

abstract：:Huntington's Disease (HD) is a genetic neurodegenerative disease caused by a CAG expansion in the gene encoding Huntingtin (Htt). It is characterized by chorea, cognitive, and psychiatric disorders. The most affected brain region is the striatum, and the clinical symptoms are directly correlated to the rate of striata...

journal_title：Frontiers in neurology

authors： Moumné L,Betuing S,Caboche J

更新日期：2013-10-23 00:00:00