Bacterial community composition in the salivary glands of triatomines (Hemiptera: Reduviidae).

abstract：BACKGROUND:Salmonella enterica serovar Typhi is transmitted by fecally contaminated food and water and causes approximately 22 million typhoid fever infections worldwide each year. Most cases occur in developing countries, where approximately 4% of patients develop intestinal perforation (IP). In Kasese District, Ugand...

journal_title：PLoS neglected tropical diseases

authors： Walters MS,Routh J,Mikoleit M,Kadivane S,Ouma C,Mubiru D,Mbusa B,Murangi A,Ejoku E,Rwantangle A,Kule U,Lule J,Garrett N,Halpin J,Maxwell N,Kagirita A,Mulabya F,Makumbi I,Freeman M,Joyce K,Hill V,Downing R,Mint

更新日期：2014-03-06 00:00:00

abstract：BACKGROUND:Of the three diseases targeted for eradication by WHO, two are so-called Neglected Tropical Diseases (NTDs)-guinea worm disease (GWD) and yaws. The Guinea Worm Eradication Programme (GWEP) is in its final stages, with only 25 reported in 2016. However, global eradication still requires certification by WHO o...

journal_title：PLoS neglected tropical diseases

authors： Fitzpatrick C,Sankara DP,Agua JF,Jonnalagedda L,Rumi F,Weiss A,Braden M,Ruiz-Tiben E,Kruse N,Braband K,Biswas G

更新日期：2017-10-05 00:00:00

abstract：BACKGROUND:The diagnosis of Strongyloides stercoralis (S. stercoralis) infection is hampered by the suboptimal sensitivity of fecal-based tests. Serological methods are believed to be more sensitive, although assessing their accuracy is difficult because of the lack of sensitivity of a fecal-based reference ("gold") st...

journal_title：PLoS neglected tropical diseases

authors： Bisoffi Z,Buonfrate D,Sequi M,Mejia R,Cimino RO,Krolewiecki AJ,Albonico M,Gobbo M,Bonafini S,Angheben A,Requena-Mendez A,Muñoz J,Nutman TB

更新日期：2014-01-09 00:00:00

abstract：BACKGROUND:Miltefosine (MIL) is an oral antileishmanial drug used for treatment of visceral leishmaniasis (VL) in the Indian subcontinent. Recent reports indicate a significant decline in its efficacy with a high rate of relapse in VL as well as post kala-azar dermal leishmaniasis (PKDL). We investigated the parasitic ...

journal_title：PLoS neglected tropical diseases

authors： Deep DK,Singh R,Bhandari V,Verma A,Sharma V,Wajid S,Sundar S,Ramesh V,Dujardin JC,Salotra P

更新日期：2017-06-02 00:00:00

abstract：BACKGROUND:Trachoma, caused by Chlamydia trachomatis (Ct), is the leading infectious cause of blindness. Sequence-based analysis of the multiple strains typically present in endemic communities may be informative for epidemiology, transmission, response to treatment, and understanding the host response. METHODS:Conjun...

journal_title：PLoS neglected tropical diseases

authors： Andreasen AA,Burton MJ,Holland MJ,Polley S,Faal N,Mabey DC,Bailey RL

更新日期：2008-09-24 00:00:00

abstract：:Entamoeba histolytica, a microaerophilic enteric protozoan parasite, causes amebic colitis and extra intestinal abscesses in millions of inhabitants of endemic areas. Trophozoites of E. histolytica are exposed to a variety of reactive oxygen and nitrogen species during infection. Since E. histolytica lacks key compone...

journal_title：PLoS neglected tropical diseases

authors： Husain A,Sato D,Jeelani G,Soga T,Nozaki T

更新日期：2012-01-01 00:00:00

abstract：:Enterotoxigenic Escherichia coli (ETEC) is one of the most common diarrheal pathogens in the low- and middle-income regions of the world, however a systematic examination of the genomic content of isolates from Chile has not yet been undertaken. Whole genome sequencing and comparative analysis of a collection of 125 E...

journal_title：PLoS neglected tropical diseases

authors： Rasko DA,Del Canto F,Luo Q,Fleckenstein JM,Vidal R,Hazen TH

更新日期：2019-11-20 00:00:00

abstract：:The Qinghai-Tibet plateau is a natural plague focus and is the largest such focus in China. In this area, while Marmota himalayana is the primary host, a total of 18 human plague outbreaks associated with Tibetan sheep (78 cases with 47 deaths) have been reported on the Qinghai-Tibet plateau since 1956. All of the ind...

journal_title：PLoS neglected tropical diseases

authors： Dai R,Wei B,Xiong H,Yang X,Peng Y,He J,Jin J,Wang Y,Zha X,Zhang Z,Liang Y,Zhang Q,Xu J,Wang Z,Li W

更新日期：2018-08-16 00:00:00

abstract：BACKGROUND:Leprosy, caused by Mycobacterium leprae, affects over 200,000 people annually worldwide and remains endemic in the ethnically diverse, mountainous and underdeveloped southwestern provinces of China. Delayed diagnosis of leprosy persists in China, thus, additional knowledge to support early diagnosis, especia...

journal_title：PLoS neglected tropical diseases

authors： Chen X,You YG,Yuan YH,Yuan LC,Wen Y

更新日期：2019-04-24 00:00:00

abstract：BACKGROUND:The IAEA colony is the only one available for mass rearing of Glossina pallidipes, a vector of human and animal African trypanosomiasis in eastern Africa. This colony is the source for Sterile Insect Technique (SIT) programs in East Africa. The source population of this colony is unclear and its genetic dive...

journal_title：PLoS neglected tropical diseases

authors： Ciosi M,Masiga DK,Turner CM

更新日期：2014-02-13 00:00:00

abstract：BACKGROUND:African trypanosomosis, primarily transmitted by tsetse flies, remains a serious public health and economic challenge in sub-Saharan Africa. Interventions employing natural repellents from non-preferred hosts of tsetse flies represent a promising management approach. Although zebras have been identified as n...

journal_title：PLoS neglected tropical diseases

authors： Olaide OY,Tchouassi DP,Yusuf AA,Pirk CWW,Masiga DK,Saini RK,Torto B

更新日期：2019-06-10 00:00:00

abstract：:Leptospirosis is a globally distributed bacterial infectious disease caused by pathogenic members of the genus Leptospira. Infection can lead to illness ranging from mild and non-specific to severe, with jaundice, kidney and liver dysfunction, and widespread endothelial damage. The adhesion of pathogenic Leptospira sp...

journal_title：PLoS neglected tropical diseases

authors： Evangelista KV,Hahn B,Wunder EA Jr,Ko AI,Haake DA,Coburn J

更新日期：2014-10-02 00:00:00

abstract：BACKGROUND:Nifurtimox eflornithine combination therapy (NECT) to treat human African trypanosomiasis (HAT), commonly called sleeping sickness, was added to the World Health Organisation's (WHO) Essential Medicines List in 2009 and to the Paediatric List in 2012. NECT was further tested and documented in a phase IIIb cl...

journal_title：PLoS neglected tropical diseases

authors： Kuemmerle A,Schmid C,Kande V,Mutombo W,Ilunga M,Lumpungu I,Mutanda S,Nganzobo P,Ngolo D,Kisala M,Valverde Mordt O

更新日期：2020-01-27 00:00:00

abstract：BACKGROUND:Vector-borne transmission of Trypanosoma cruzi is seen exclusively in the Americas where an estimated 8 million people are infected with the parasite. Significant research in southern Peru has been conducted to understand T. cruzi infection and vector control, however, much less is known about the burden of ...

journal_title：PLoS neglected tropical diseases

authors： Alroy KA,Huang C,Gilman RH,Quispe-Machaca VR,Marks MA,Ancca-Juarez J,Hillyard M,Verastegui M,Sanchez G,Cabrera L,Vidal E,Billig EM,Cama VA,Náquira C,Bern C,Levy MZ,Working Group on Chagas Disease in Peru.

更新日期：2015-05-22 00:00:00

abstract：BACKGROUND:Leptospirosis is a neglected zoonosis affecting animals and humans caused by infection with Leptospira. The bacteria can survive outside of hosts for long periods of time in soil and water. While identification of Leptospira species from human cases and animal reservoirs are increasingly reported, little is ...

journal_title：PLoS neglected tropical diseases

authors： Mason MR,Encina C,Sreevatsan S,Muñoz-Zanzi C

更新日期：2016-08-16 00:00:00

abstract：BACKGROUND:Large-scale deworming programs have, to date, mostly targeted preschool- and school-age children. As community-based deworming programs become more common, deworming will be offered to women of reproductive age. The World Health Organization recommends preventive chemotherapy be administered to pregnant wome...

journal_title：PLoS neglected tropical diseases

authors： St-Denis K,Blouin B,Rahme E,Casapia M,Montresor A,Mupfasoni D,Mbabazi PS,Gyorkos TW

更新日期：2020-01-30 00:00:00

abstract：BACKGROUND:The use of DNA microarray technology to study global Schistosoma gene expression has led to the rapid identification of novel biological processes, pathways or associations. Implementation of standardized DNA microarray protocols across laboratories would assist maximal interpretation of generated datasets a...

journal_title：PLoS neglected tropical diseases

authors： Fitzpatrick JM,Protasio AV,McArdle AJ,Williams GA,Johnston DA,Hoffmann KF

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Schistosomiasis remains a significant health burden in many areas of the world. Morbidity control, focused on limiting infection intensity through periodic delivery of anti-schistosomal medicines, is the thrust of current World Health Organization guidelines (2006) for reduction of Schistosoma-related diseas...

journal_title：PLoS neglected tropical diseases

authors： Wang X,Gurarie D,Mungai PL,Muchiri EM,Kitron U,King CH

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Cutaneous leishmaniasis (CL) is treated with parenteral drugs for decades with decreasing rate cures. Miltefosine is an oral medication with anti-leishmania activity and may increase the cure rates and improve compliance. METHODOLOGY/PRINCIPAL FINDINGS:This study is a randomized, open-label, controlled clin...

journal_title：PLoS neglected tropical diseases

authors： Machado PR,Ampuero J,Guimarães LH,Villasboas L,Rocha AT,Schriefer A,Sousa RS,Talhari A,Penna G,Carvalho EM

更新日期：2010-12-21 00:00:00

abstract：BACKGROUND:There are health risks associated with wastewater and fecal sludge management and use, but little is known about the magnitude, particularly in rapidly growing urban settings of low- and middle-income countries. We assessed the point-prevalence and risk factors of intestinal parasite infections in people wit...

journal_title：PLoS neglected tropical diseases

authors： Fuhrimann S,Winkler MS,Kabatereine NB,Tukahebwa EM,Halage AA,Rutebemberwa E,Medlicott K,Schindler C,Utzinger J,Cissé G

更新日期：2016-03-03 00:00:00

abstract：BACKGROUND:treatment of Mycobacterium ulcerans disease, or Buruli ulcer (BU), has shifted from surgery to treatment with streptomycin(STR)+rifampin(RIF) since 2004 based on studies in a mouse model and clinical trials. We tested two entirely oral regimens for BU treatment, rifampin(RIF)+clarithromycin(CLR) and rifapent...

journal_title：PLoS neglected tropical diseases

authors： Almeida D,Converse PJ,Ahmad Z,Dooley KE,Nuermberger EL,Grosset JH

更新日期：2011-01-04 00:00:00

abstract：BACKGROUND:Imported strongyloidiasis is increasingly being diagnosed in non-endemic areas. The aim of this study was to describe the epidemiological, clinical and microbiological characteristics of patients with imported strongyloidiasis in Spain. METHODOLOGY:This is an observational retrospective study that included ...

journal_title：PLoS neglected tropical diseases

authors： Salvador F,Treviño B,Chamorro-Tojeiro S,Sánchez-Montalvá A,Herrero-Martínez JM,Rodríguez-Guardado A,Serre-Delcor N,Torrús D,Goikoetxea J,Zubero Z,Velasco M,Sulleiro E,Molina I,López-Vélez R,Pérez-Molina JA,on behalf the +RE

更新日期：2019-05-16 00:00:00

abstract：BACKGROUND:Scrub typhus is a neglected tropical disease that causes acute febrile illness. Diagnosis is made based upon serology, or detection of the causative agent-Orientia tsutsugamushi-using PCR or in vitro isolation. The enzyme-linked immunosorbent assay (ELISA) is an objective and reproducible means of detecting ...

journal_title：PLoS neglected tropical diseases

authors： Saraswati K,Phanichkrivalkosil M,Day NPJ,Blacksell SD

更新日期：2019-02-04 00:00:00

abstract：:[This corrects the article DOI: 10.1371/journal.pntd.0008129.]. ...

journal_title：PLoS neglected tropical diseases

authors： Alzaylaee H,Collins RA,Rinaldi G,Shechonge A,Ngatunga B,Morgan ER,Genner MJ

更新日期：2020-09-01 00:00:00

abstract：:The major arboviral diseases in mainland China include Japanese encephalitis, dengue fever, Crimean-Congo hemorrhagic fever (also known as Xinjiang hemorrhagic fever), and tick-borne encephalitis. These and other newly found arbovirus infections due to Banna virus and Tahyna virus contribute to a large and relatively ...

journal_title：PLoS neglected tropical diseases

authors： Gao X,Nasci R,Liang G

更新日期：2010-04-27 00:00:00

abstract：BACKGROUND:Taenia solium cysticercosis/taeniosis is emerging as a serious public health and economic problem in many developing countries. This study was conducted to determine prevalence and risk factors of human T. solium infections in Mbeya Region, Tanzania. METHODS AND FINDINGS:A cross-sectional survey was conduct...

journal_title：PLoS neglected tropical diseases

authors： Mwanjali G,Kihamia C,Kakoko DV,Lekule F,Ngowi H,Johansen MV,Thamsborg SM,Willingham AL 3rd

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Cryptosporidium is a protozoan parasite that causes mild to severe diarrhoeal disease in humans. To date, several commercial companies have developed rapid immunoassays for the detection of Cryptosporidium infection. However, the challenge is to identify an accurate, simple and rapid diagnostic tool for the ...

journal_title：PLoS neglected tropical diseases

authors： Manouana GP,Lorenz E,Mbong Ngwese M,Nguema Moure PA,Maiga Ascofaré O,Akenten CW,Amuasi J,Rakotozandrindrainy N,Rakotozandrindrainy R,Mbwana J,Lusingu J,Byrne N,Melhem S,Zinsou JF,Adegbite RB,Hogan B,Winter D,May J,Kre

更新日期：2020-07-13 00:00:00

abstract：BACKGROUND:Hantavirus pulmonary syndrome (HPS) is a life threatening disease transmitted by the rodent Oligoryzomys longicaudatus in Chile. Hantavirus outbreaks are typically small and geographically confined. Several studies have estimated risk based on spatial and temporal distribution of cases in relation to climate...

journal_title：PLoS neglected tropical diseases

authors： Nsoesie EO,Mekaru SR,Ramakrishnan N,Marathe MV,Brownstein JS

更新日期：2014-04-24 00:00:00

abstract：INTRODUCTION:Individuals exposed to malaria infections for a long time develop immune responses capable of blocking Plasmodium transmission to mosquito vectors, potentially limiting parasite spreading in nature. Development of a malaria TB vaccine requires a better understanding of the mechanisms and main effectors res...

journal_title：PLoS neglected tropical diseases

authors： Vallejo AF,Rubiano K,Amado A,Krystosik AR,Herrera S,Arévalo-Herrera M

更新日期：2016-06-29 00:00:00

abstract：:Mosquito-borne diseases continue to remain major threats to human and animal health and impediments to socioeconomic development. Increasing mosquito resistance to chemical insecticides is a great public health concern, and new strategies/technologies are necessary to develop the next-generation of vector control tool...

journal_title：PLoS neglected tropical diseases

authors： Phanse Y,Dunphy BM,Perry JL,Airs PM,Paquette CC,Carlson JO,Xu J,Luft JC,DeSimone JM,Beaty BJ,Bartholomay LC

更新日期：2015-05-21 00:00:00