Nanotherapeutics for Treatment of Pulmonary Arterial Hypertension.

abstract：:One goal of advanced information and communication technology is to simplify work. However, there is growing consensus regarding the negative consequences of inappropriate workload on employee's health and the safety of persons. In order to develop a method for continuous mental workload monitoring, we implemented a t...

journal_title：Frontiers in physiology

authors： Radüntz T

更新日期：2017-12-08 00:00:00

abstract：Purpose:This study aimed to evaluate effects of remote ischemic preconditioning (RIPC) on myocardial injury in patients undergoing off-pump coronary artery bypass graft surgery (OPCABG). Methods:Sixty-five patients scheduled for the OPCABG were randomly assigned to control (n = 32) or RIPC group (n = 33). All patients...

journal_title：Frontiers in physiology

authors： Wang H,Lyu Y,Liao Q,Jin L,Xu L,Hu Y,Yu Y,Guo K

更新日期：2019-04-29 00:00:00

abstract：PURPOSE:The aim of present investigation was to evaluate marginal bone level after 5-year follow-up of implants placed in healed ridges and fresh extraction sockets in maxilla with immediate loading protocol. MATERIALS AND METHODS:Thirty-six patients in need of a single-tooth replacement in the anterior maxilla receiv...

journal_title：Frontiers in physiology

authors： Berberi AN,Sabbagh JM,Aboushelib MN,Noujeim ZF,Salameh ZA

更新日期：2014-01-31 00:00:00

abstract：:Blood pressure regulation is a prime example of homeostatic regulation. However, some characteristics of the cardiovascular system better match a non-linear self-organized system than a homeostatic one. To determine whether blood pressure regulation is self-organized, we repeated the seminal demonstration of self-orga...

journal_title：Frontiers in physiology

authors： Fortrat JO,Levrard T,Courcinous S,Victor J

更新日期：2016-03-31 00:00:00

abstract：:It is assumed that a properly timed circadian clock enhances fitness, but only few studies have truly demonstrated this in animals. We raised each of the three classical Drosophila period mutants for >50 generations in the laboratory in competition with wildtype flies. The populations were either kept under a conventi...

journal_title：Frontiers in physiology

authors： Horn M,Mitesser O,Hovestadt T,Yoshii T,Rieger D,Helfrich-Förster C

更新日期：2019-11-01 00:00:00

abstract：:Overconsumption of fructose leads to metabolic syndrome as a result of hypertension, insulin resistance, and hyperlipidemia. In this study, the renal function of animals submitted to high fructose intake was analyzed from weaning to adulthood using in vivo and ex vivo methods, being compared with a normal control grou...

journal_title：Frontiers in physiology

authors： Yokota R,Ronchi FA,Fernandes FB,Jara ZP,Rosa RM,Leite APO,Fiorino P,Farah V,do Nascimento NRF,Fonteles MC,Casarini DE

更新日期：2018-10-10 00:00:00

abstract：:In our previous study, we reported a high temperature adapted strain (HTAS) of the predatory mite Neoseiulus barkeri was artificially selected via a long-term heat acclimation (35°C) and frequent heat hardenings. To understand the molecular basis of heat acclimation, 'omics' analyses were performed to compare the diff...

journal_title：Frontiers in physiology

authors： Tian CB,Li YY,Huang J,Chu WQ,Wang ZY,Liu H

更新日期：2020-04-29 00:00:00

abstract：:[This corrects the article DOI: 10.3389/fphys.2020.00302.]. ...

journal_title：Frontiers in physiology

authors： Semple C,Riveros D,Nagy JA,Rutkove SB,Mortreux M

更新日期：2020-07-03 00:00:00

abstract：:To understand dynamic changes in polyamines (PAs) forms and components of polyamine metabolism in zoysiagrass (Zoysia japonica Steud.) response to salt stress with exogenous spermidine (Spd) application, two Chinese zoysia cultivars, z081 and z057, were exposed to sodium chloride stress for 2, 4, 6, and 8 days. The z0...

journal_title：Frontiers in physiology

authors： Li S,Cui L,Zhang Y,Wang Y,Mao P

更新日期：2017-04-06 00:00:00

abstract：:Surface electromyography (sEMG) is a popular research tool in sport and rehabilitation sciences. Common study designs include the comparison of sEMG amplitudes collected from different muscles as participants perform various exercises and techniques under different loads. Based on such comparisons, researchers attempt...

journal_title：Frontiers in physiology

authors： Vigotsky AD,Halperin I,Lehman GJ,Trajano GS,Vieira TM

更新日期：2018-01-04 00:00:00

abstract：:Anatomical evidence in several species shows highly heterogeneous fat distribution in the atrial and ventricular myocardium. Atrial appendages have fat deposits, and more so on the posterior left atrium. Although such fat distributions are considered normal, fatty infiltration is regarded arrhythmogenic, and various c...

journal_title：Frontiers in physiology

authors： Anumonwo JMB,Herron T

更新日期：2018-01-22 00:00:00

abstract：:Studies have revealed a robust and independent correlation between chronic kidney disease (CKD) and cardiovascular (CV) events, including death, heart failure, and myocardial infarction. Recent clinical trials extend this range of adverse CV events, including malignant ventricular arrhythmias and sudden cardiac death ...

journal_title：Frontiers in physiology

authors： Kiuchi MG,Ho JK,Nolde JM,Gavidia LML,Carnagarin R,Matthews VB,Schlaich MP

更新日期：2020-01-14 00:00:00

abstract：:Glucose metabolism is a biologically important metabolic process. Glycogen synthase kinase (GSK-3) is a key enzyme located in the middle of the sugar metabolism pathway that can regulate the energy metabolism process in the body through insulin signaling. This paper mainly explores the regulatory effect of glycogen sy...

journal_title：Frontiers in physiology

authors： Ding YJ,Li GY,Xu CD,Wu Y,Zhou ZS,Wang SG,Li C

更新日期：2020-11-25 00:00:00

abstract：:Neuromuscular training in young athletes improves performance and decreases the risk of injuries during sports activities. These effects are primarily ascribed to the enhancement of muscle strength and power but also balance, speed and agility. However, most studies have failed to demonstrate significant improvement i...

journal_title：Frontiers in physiology

authors： Zemková E,Hamar D

更新日期：2018-04-11 00:00:00

abstract：:Aim: mircoRNAs (miRNAs), small non-coding RNAs regulating gene expression, are stably secreted into the blood and circulating miRNAs (c-miRNAs) may play an important role in cell-cell communication. Furthermore, c-miRNAs might serve as novel biomarkers of the current vascular cell status. Here, we examined how the lev...

journal_title：Frontiers in physiology

authors： Wahl P,Wehmeier UF,Jansen FJ,Kilian Y,Bloch W,Werner N,Mester J,Hilberg T

更新日期：2016-12-26 00:00:00

abstract：:Perfluorooctanoic acid (PFOA) has been detected in various water bodies and caused harm to aquatic organisms. The aim of this study was to investigate the cytotoxicity and mechanism associated with autophagy and oxidative stress after exposure to PFOA (0, 1, 10, 100 μg/L) for 12 h on lymphocytes, which was isolated fr...

journal_title：Frontiers in physiology

authors： Tang J,Lu X,Chen F,Ye X,Zhou D,Yuan J,He J,Chen B,Shan X,Jiang J,Liu W,Zhang H

更新日期：2018-12-05 00:00:00

abstract：:Genome-wide association studies and physiological investigations have linked alterations in acid-base transporters to hypertension. Accordingly, Na(+)-coupled HCO(-) 3-transporters, Na(+)/H(+)-exchangers, and anion-exchangers have emerged as putative mechanistic components in blood pressure disturbances. Even though h...

journal_title：Frontiers in physiology

authors： Boedtkjer E,Aalkjaer C

更新日期：2013-12-24 00:00:00

abstract：:Hypoxia has important effects on biological activity in crustaceans, and modulation of energy metabolism is a crucial aspect of crustaceans' ability to respond to hypoxia. The adenosine 5'-monophosphate (AMP)-activated protein kinase (AMPK) enzyme is very important in cellular energy homeostasis; however, little infor...

journal_title：Frontiers in physiology

authors： Sun S,Gu Z,Fu H,Zhu J,Ge X,Wu X

更新日期：2018-06-14 00:00:00

abstract：:Circadian clocks are endogenous oscillators essential for orchestrating daily rhythms in physiology, metabolism and behavior. While mouse models have been instrumental to elucidate the molecular mechanism of circadian rhythm generation, our knowledge about the molecular makeup of circadian oscillators in humans is sti...

journal_title：Frontiers in physiology

authors： Börding T,Abdo AN,Maier B,Gabriel C,Kramer A

更新日期：2019-05-09 00:00:00

abstract：:Immunity and cellular metabolism are tightly interconnected but it is not clear whether different pathogens elicit specific metabolic responses. To address this issue, we studied differential metabolic regulation in peripheral blood mononuclear cells (PBMCs) of healthy volunteers challenged by Candida albicans, Borrel...

journal_title：Frontiers in physiology

authors： Zhang X,Mardinoglu A,Joosten LAB,Kuivenhoven JA,Li Y,Netea MG,Groen AK

更新日期：2018-02-27 00:00:00

abstract：:Muscle tone represents one of the important concepts for characterizing changes in the state of the developing nervous system. It can be manifested in the level of activity of flexors and extensors and in muscle reactions to its passive stretching (StR) or shortening (ShR). Here we investigated such reactions in a coh...

journal_title：Frontiers in physiology

authors： Solopova IA,Zhvansky DS,Dolinskaya IY,Keshishian ES,Selionov VA,Sylos-Labini F,Lacquaniti F,Ivanenko Y

更新日期：2019-09-13 00:00:00

abstract：:The sympathetic nervous system (SNS) contribution to long-term setting of blood pressure (BP) and hence hypertension has been a continuing controversy over many decades. However, the contribution of increased sympathetic vasomotor tone to the heart, kidney, and blood vessels has been suggested as a major influence on ...

journal_title：Frontiers in physiology

authors： Head GA,Jackson KL,Gueguen C

更新日期：2019-12-12 00:00:00

abstract：:Sudden cardiac death caused by ventricular arrhythmias is among the leading causes of mortality, with approximately half of all deaths attributed to heart disease worldwide. Periodic repolarization dynamics (PRD) is a novel marker of repolarization instability and strong predictor of death in patients post-myocardial ...

journal_title：Frontiers in physiology

authors： Ang R,Marina N

更新日期：2020-03-18 00:00:00

abstract：:Activation of autonomic neural pathways by chronic hypertensive stimuli plays a significant role in pathogenesis of hypertension. Here, we proposed that even a single acute hypertensive stimulus will activate neural and immune pathways that may be important in initiation of memory imprinting seen in chronic hypertensi...

journal_title：Frontiers in physiology

authors： Zubcevic J,Santisteban MM,Perez PD,Arocha R,Hiller H,Malphurs WL,Colon-Perez LM,Sharma RK,de Kloet A,Krause EG,Febo M,Raizada MK

更新日期：2017-08-31 00:00:00

abstract：:Excessive alcohol consumption is associated with hepatic steatosis and dysregulation of the gut microbiota in patients with alcohol use disorder (AUD). However, how gut microbiota responds when patients stop drinking has not been well studied. In this study, we use shotgun metagenomic sequencing to elucidate the alter...

journal_title：Frontiers in physiology

authors： Gao B,Emami A,Zhou R,Lang S,Duan Y,Wang Y,Jiang L,Loomba R,Brenner DA,Stärkel P,Schnabl B

更新日期：2020-04-24 00:00:00

abstract：:The generation of neural network dynamics relies on the interactions between the intrinsic and synaptic properties of their neural components. Moreover, neuromodulators allow networks to change these properties and adjust their activity to specific challenges. Endogenous continuous ("tonic") neuromodulation can regula...

journal_title：Frontiers in physiology

authors： Peña-Ortega F

更新日期：2012-07-20 00:00:00

abstract：:Cortical spreading depolarisation (CSD) is a transient disruption of ion balance that propagates along the cortex. It has been identified as an important factor in the progression of cerebral damage associated with stroke or traumatic brain injury. We analysed local field potential signals during CSD in old and young ...

journal_title：Frontiers in physiology

authors： Makra P,Menyhárt Á,Bari F,Farkas E

更新日期：2018-11-08 00:00:00

abstract：:Inflammatory bowel diseases (IBD), which include Crohn's disease and ulcerative colitis, are chronic inflammatory disorders that can affect the whole gastrointestinal tract or the colonic mucosal layer. Current therapies aiming to suppress the exaggerated immune response in IBD largely rely on compounds with non-satis...

journal_title：Frontiers in physiology

authors： Schreiber D,Marx L,Felix S,Clasohm J,Weyland M,Schäfer M,Klotz M,Lilischkis R,Erkel G,Schäfer KH

更新日期：2017-08-07 00:00:00

abstract：:In the quest for a viable non-gravity dependent method to "lift weights" in space, our laboratory introduced iso-inertial resistance (YoYo™) exercise using spinning flywheel(s), more than 25 years ago. After being thoroughly tested in individuals subjected to various established spaceflight analogs, a multi-mode YoYo™...

journal_title：Frontiers in physiology

authors： Tesch PA,Fernandez-Gonzalo R,Lundberg TR

更新日期：2017-04-27 00:00:00

abstract：:Background: Molting is a crucial physiological behavior during arthropod growth. In the past few years, molting as well as chitin biosynthesis triggered by molting, is subject to regulation by miRNAs. However, how many miRNAs are involved in insect molting at the genome-wide level remains unknown. Results: We deeply s...

journal_title：Frontiers in physiology

authors： Chen J,Li TC,Pang R,Yue XZ,Hu J,Zhang WQ

更新日期：2018-12-20 00:00:00