Expanding Spectrum of Toxoplasma gondii: Thymoma and Toxoplasmic Encephalitis.

abstract：BACKGROUND:Ombitasvir, paritaprevir with ritonavir, and dasabuvir (OBV/PTV/r ± DSV) ±ribavirin (RBV) are approved to treat hepatitis C virus (HCV) genotype 1 and 4 infection. Here, we investigate the safety and efficacy of OBV/PTV/r + DSV ±RBV for HCV genotype 1, and OBV/PTV/r + RBV for HCV genotype 4, in human immunod...

journal_title：Open forum infectious diseases

authors： Rockstroh JK,Orkin C,Viani RM,Wyles D,Luetkemeyer AF,Lazzarin A,Soto-Malave R,Nelson MR,Bhagani SR,Klinker HHF,Rizzardini G,Girard PM,Tural C,Shulman NS,Mobashery N,Hu YB,Fredrick LM,Pilot-Matias T,Trinh R,Gane E

更新日期：2017-07-22 00:00:00

abstract：:[This corrects the article DOI: 10.1093/ofid/ofv111.]. ...

journal_title：Open forum infectious diseases

authors：

更新日期：2015-09-04 00:00:00

abstract：BACKGROUND:Endothelial activation and dysfunction play a central role in the pathogenesis of sepsis and viral hemorrhagic fevers. Hantaviral disease is a viral hemorrhagic fever and is characterized by capillary dysfunction, although the underlying mechanisms for hantaviral disease are not fully elucidated. METHODS:Th...

journal_title：Open forum infectious diseases

authors： Connolly-Andersen AM,Thunberg T,Ahlm C

更新日期：2014-05-29 00:00:00

abstract：:Background.  First- and second-generation smallpox vaccines are contraindicated in individuals infected with human immunodeficiency virus (HIV). A new smallpox vaccine is needed to protect this population in the context of biodefense preparedness. The focus of this study was to compare the safety and immunogenicity of...

journal_title：Open forum infectious diseases

authors： Overton ET,Stapleton J,Frank I,Hassler S,Goepfert PA,Barker D,Wagner E,von Krempelhuber A,Virgin G,Meyer TP,Müller J,Bädeker N,Grünert R,Young P,Rösch S,Maclennan J,Arndtz-Wiedemann N,Chaplin P

更新日期：2015-05-05 00:00:00

abstract：:Vancomycin is commonly added as empiric therapy for febrile neutropenia. A retrospective chart review was conducted at a large community teaching institution to evaluate vancomycin use in oncology patients. The results revealed that a majority of empiric vancomycin therapy was inappropriate, raising concern for antibi...

journal_title：Open forum infectious diseases

authors： Libuit J,Whitman A,Wolfe R,Washington CS

更新日期：2014-04-10 00:00:00

abstract：Background:Human babesiosis is a common zoonosis caused by Babesia and is attracting an increasing concern worldwide. The natural course of babesiosis infection and how the human immune system changes during the course of babesiosis infection are not clear. Methods:We followed up 1 case infected with Babesia venatorum...

journal_title：Open forum infectious diseases

authors： Zhao L,Jiang R,Jia N,Ning N,Zheng Y,Huo Q,Sun Y,Yuan T,Jiang B,Li T,Liu H,Liu X,Chu Y,Wei R,Bian C,Wang H,Song J,Wang H,Jiang J,Cao W

更新日期：2020-02-18 00:00:00

abstract：:[This corrects the article DOI: 10.1093/ofid/ofx156.][This corrects the article DOI: 10.1093/ofid/ofx156.]. ...

journal_title：Open forum infectious diseases

authors：

更新日期：2018-01-30 00:00:00

abstract：BACKGROUND:Intra-abdominal infections (IAI) constitute a common reason for hospitalization. However, there is lack of standardization in empiric management of (1) anaerobes, (2) enterococci, (3) fungi, and (4) multidrug-resistant organisms (MDRO). The recommendation is to institute empiric coverage for some of these or...

journal_title：Open forum infectious diseases

authors： Marcus G,Levy S,Salhab G,Mengesha B,Tzuman O,Shur S,Burke E,Mayeda RC,Cochavi L,Perluk I,Zaidenstein R,Lazarovitch T,Dadon M,Marchaim D

更新日期：2016-12-20 00:00:00

abstract：:We investigated the microbial burden on the operating room environment when patients on contact precautions for a multidrug-resistant pathogen received surgery. Our study demonstrated that the perioperative environment was contaminated with aerobic bacteria and methicillin-resistant Staphylococcus aureus (MRSA) after ...

journal_title：Open forum infectious diseases

authors： Kanamori H,Rutala WA,Gergen MF,Weber DJ

更新日期：2020-10-27 00:00:00

abstract：:The year 2019 brought about a multitude of innovations in clinical infectious diseases. With the continued rise of antimicrobial resistance (AMR), advances in diagnostics and newly available antibiotics offer additional strategies for combating this threat, but the broken antibiotic market serves as an impediment to f...

journal_title：Open forum infectious diseases

authors： Moss S,Boucher HW

更新日期：2020-03-23 00:00:00

abstract：BACKGROUND:Monitoring of immune function, measured by CD4 cell count, is an essential service for people with Human Immunodeficiency Virus (HIV). Prescription of antiretroviral (ARV) medications is contingent on CD4 cell count; patients without regular CD4 monitoring are unlikely to receive ARVs when indicated. This st...

journal_title：Open forum infectious diseases

authors： Davis AC,Watson G,Pourat N,Kominski GF,Roby DH

更新日期：2014-06-05 00:00:00

abstract：:Using data from 3 private healthcare claims repositories, we evaluated the incidence of pneumococcal disease among adults with US Advisory Committee on Immunization Practices (ACIP) defined at-risk conditions or rheumatoid arthritis, lupus, Crohn's disease, and neuromuscular disorder/seizures and those with traditiona...

journal_title：Open forum infectious diseases

authors： Pelton SI,Shea KM,Weycker D,Farkouh RA,Strutton DR,Edelsberg J

更新日期：2015-03-20 00:00:00

abstract：:Respiratory syncytial virus (RSV) is an increasingly recognized cause of acute respiratory infection (ARI) in adults. We compared the crude in-hospital mortality of patients with RSV infection alone with that of patients with RSV-bacterial coinfection. Overall, 12 144 hospitalized patients with ARI were screened for R...

journal_title：Open forum infectious diseases

authors： Godefroy R,Giraud-Gatineau A,Jimeno MT,Edouard S,Meddeb L,Zandotti C,Chaudet H,Colson P,Raoult D,Cassir N

更新日期：2020-11-12 00:00:00

abstract：:Both dengue virus (DENV) and hepatitis C virus (HCV) belong to the Flaviviridae family and could induce hepatitis. We aimed to investigate the interference between them. In total, 515 patients confirmed with dengue fever (DF) were enrolled. Thirty-two patients (6.21%) were seropositive for anti-HCV; 12 of 32 anti-HCV-...

journal_title：Open forum infectious diseases

authors： Liang PC,Chen KY,Huang CH,Chang K,Lu PL,Yeh ML,Huang CF,Huang CI,Hsieh MH,Dai CY,Lin ZY,Chen SC,Chuang WL,Chen YH,Huang JF,Yu ML

更新日期：2020-07-03 00:00:00

abstract：Background:Patients with chronic hepatitis C virus (HCV) infection and active or previous hepatitis B virus (HBV) are at risk of HBV reactivation (HBV-R) during direct-acting antiviral (DAA) therapy. Recent reports suggest that HBV-R may even occur several months after completion of DAA therapy. The aim of this study w...

journal_title：Open forum infectious diseases

authors： Mücke MM,Mücke VT,Peiffer KH,Sarrazin C,Zeuzem S,Berger A,Vermehren J

更新日期：2018-12-15 00:00:00

abstract：:Human immunodeficiency virus-infected women with central adiposity switched to raltegravir-based antiretroviral therapy immediately or after 24 weeks. No statistically significant changes in computed tomography-quantified visceral adipose tissue (VAT) or subcutaneous fat were observed, although 48 weeks of raltegravir...

journal_title：Open forum infectious diseases

authors： Lake JE,McComsey GA,Hulgan T,Wanke CA,Mangili A,Walmsley SL,Currier JS

更新日期：2015-04-26 00:00:00

abstract：BACKGROUND:Avian influenza A/H5N1 has threatened human health for nearly 2 decades. Avian influenza A vaccine without adjuvant is poorly immunogenic. A flexible rapid tactic for mass vaccination will be needed if a pandemic occurs. METHODS:A multicenter, randomized, blinded phase 1 clinical trial evaluated safety and ...

journal_title：Open forum infectious diseases

authors： Mulligan MJ,Bernstein DI,Frey S,Winokur P,Rouphael N,Dickey M,Edupuganti S,Spearman P,Anderson E,Graham I,Noah DL,Mangal B,Kim S,Hill H,Whitaker J,Emery W,Beck A,Stephens K,Hartwell B,Ogilvie M,Rimann N,Osinski

更新日期：2014-11-18 00:00:00

abstract：Background:Plasma gelsolin (pGSN) is an abundant circulating protein quickly consumed by extensive tissue damage. Marked depletion is associated with later poor outcomes in diverse clinical circumstances. Repletion with recombinant human (rhu)-pGSN in animal models of inflammation lessens mortality and morbidity. Meth...

journal_title：Open forum infectious diseases

authors： DiNubile MJ,Levinson SL,Stossel TP,Lawrenz MB,Warawa JM

更新日期：2020-06-19 00:00:00

abstract：Background:Recent mumps outbreaks among 2-dose measles mumps rubella (MMR) vaccine recipients have raised questions regarding the potential benefits of a third dose of vaccine (MMR3). If MMR3 provides a sustained elevation in mumps antibody, it may be beneficial for certain at-risk groups or as an outbreak control meas...

journal_title：Open forum infectious diseases

authors： Latner DR,Parker Fiebelkorn A,McGrew M,Williams NJ,Coleman LA,McLean HQ,Rubin S,Hickman CJ

更新日期：2017-12-08 00:00:00

abstract：:Because of concerns about possible emergence of artemisinin resistance strains of Plasmodium falciparum in mining areas of the interior of Guyana, a 7-day artesunate trial was conducted from March to December 2014. The day-3 parasite clearance rate, the efficacy of artesunate at day 28, and polymorphism of Kelch 13 (P...

journal_title：Open forum infectious diseases

authors： Rahman R,Martin MJ,Persaud S,Ceron N,Kellman D,Musset L,Carter KH,Ringwald P

更新日期：2016-08-30 00:00:00

abstract：Background:Short-term recurrence of positive severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ribonucleic acid (RNA) polymerase chain reaction (PCR) in discharged coronavirus disease 2019 (COVID-19) patients attracts the public's concern. This study aimed to determine the clinical and epidemiological result...

journal_title：Open forum infectious diseases

authors： Chen SL,Xu H,Feng HY,Sun JF,Li X,Zhou L,Song WL,Huang SS,He JL,Deng YY,Wang RJ,Fang M

更新日期：2020-09-13 00:00:00

abstract：Background:The Short Physical Performance Battery (SPPB) is a well regarded physical functioning assessment including balance, gait speed, and chair-stand tests. Its use has not been widely assessed in human immunodeficiency virus (HIV) care. We evaluated the feasibility of integrating the SPPB into care of aging peopl...

journal_title：Open forum infectious diseases

authors： Crane HM,Miller ME,Pierce J,Willig AL,Case ML,Wilkin AM,Brown S,Asirot MG,Fredericksen RJ,Saag MS,Landay AL,High KP

更新日期：2019-03-11 00:00:00

abstract：Background:Dengue and Chikungunya viruses can cause large-scale epidemics, with attack rates of up to 80%. In Tanzania, there have been repeated outbreaks of dengue fever, the most recent in 2018 and 2019, mostly affecting the coastal areas. Despite the importance of these viruses, there is limited knowledge on the epi...

journal_title：Open forum infectious diseases

authors： Chipwaza B,Sumaye RD,Weisser M,Gingo W,Yeo NK,Amrun SN,Okumu FO,Ng LFP

更新日期：2020-12-26 00:00:00

abstract：Background:From an isolated epidemic, coronavirus disease 2019 has now emerged as a global pandemic. The availability of genomes in the public domain after the epidemic provides a unique opportunity to understand the evolution and spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus across the g...

journal_title：Open forum infectious diseases

authors： Banu S,Jolly B,Mukherjee P,Singh P,Khan S,Zaveri L,Shambhavi S,Gaur N,Reddy S,Kaveri K,Srinivasan S,Gopal DR,Siva AB,Thangaraj K,Tallapaka KB,Mishra RK,Scaria V,Sowpati DT

更新日期：2020-09-18 00:00:00

abstract：:This article provides a comprehensive review of currently available treatment options for infections due to carbapenem-resistant Enterobacteriaceae (CRE). Antimicrobial resistance in Gram-negative bacteria is an emerging and serious global public health threat. Carbapenems have been used as the "last-line" treatment f...

journal_title：Open forum infectious diseases

authors： Morrill HJ,Pogue JM,Kaye KS,LaPlante KL

更新日期：2015-05-05 00:00:00

abstract：Background:Antimicrobial stewardship interventions utilizing real-time alerting through the electronic medical record enable timely implementation of the bundle of care (BOC) for patients with severe infections, such as candidemia. Automated alerting for candidemia using the Epic stewardship module has been in place si...

journal_title：Open forum infectious diseases

authors： Pettit NN,Han Z,Nguyen CT,Choksi A,Charnot-Katsikas A,Beavis KG,Tesic V,Pisano J

更新日期：2019-10-11 00:00:00

abstract：: Background.  School closures are an important mitigation strategy during influenza pandemic: if implemented early in a local outbreak, they can slow the disease spread in the surrounding community. During seasonal influenza epidemics, school closures may occur reactively, ...

journal_title：Open forum infectious diseases

authors： Russell ES,Zheteyeva Y,Gao H,Shi J,Rainey JJ,Thoroughman D,Uzicanin A

更新日期：2016-05-25 00:00:00

abstract：Background:Maintaining retention in preexposure prophylaxis (PrEP) care among diverse patient populations will be needed to support PrEP's efficacy. We characterized patterns of PrEP care retention in a US municipal primary care health network and examined whether missed visits, a metric of care retention that is easy ...

journal_title：Open forum infectious diseases

authors： Spinelli MA,Scott HM,Vittinghoff E,Liu AY,Gonzalez R,Morehead-Gee A,Gandhi M,Buchbinder SP

更新日期：2019-02-26 00:00:00

abstract：:During the current Zika virus (ZIKV) outbreak, acute symptomatic ZIKV infection in adults appears to be a mild-to-moderate, self-limited illness. We present a case of ZIKV rash illness that improved and then relapsed without repeat exposure to ZIKV. Clinicians should be alert for relapses in patients with ZIKV infecti...

journal_title：Open forum infectious diseases

authors： Edupuganti S,Natrajan MS,Rouphael N,Lai L,Xu Y,Feldhammer M,Hill C,Patel SM,Johnson SJ,Bower M,Gorchakov R,Berry R,Murray KO,Mulligan MJ

更新日期：2017-06-22 00:00:00

abstract：:Background.  Cryptococcal meningitis is a leading cause of death in people living with human immunodeficiency virus (HIV)/acquired immune deficiency syndrome. The World Health Organizations recommends pre-antiretroviral treatment (ART) cryptococcal antigen (CRAG) screening in persons with CD4 below 100 cells/µL. We as...

journal_title：Open forum infectious diseases

authors： Letang E,Müller MC,Ntamatungiro AJ,Kimera N,Faini D,Furrer H,Battegay M,Tanner M,Hatz C,Boulware DR,Glass TR

更新日期：2015-04-02 00:00:00