Prognostic Value of Albumin/Globulin Ratio in Survival and Lymph Node Metastasis in Patients with Cancer: A Systematic Review and Meta-analysis.

abstract：:Background: Malignant biliary and/or pancreatic obstruction has often encountered in the advanced stages of periampullary and cholangicarcinomas. HabibTM Radiofrequency (RF) ablation has been successfully used in the management of various cancers of liver and pancreas. Percutaneous HPB probe (EMcision Ltd, London, UK)...

journal_title：Journal of Cancer

authors： Mizandari M,Kumar J,Pai M,Chikovani T,Azrumelashvili T,Reccia I,Habib N

更新日期：2018-01-05 00:00:00

abstract：:The incidence of colorectal cancer (CRC) ranks third among all cancers in China and improvements in screening for CRC have an important impact on prevention and control of the disease. Paraoxonase 1 (PON1) is a calcium ion-dependent hydrolase that is widely distributed in tissue. Its diagnostic value in colorectal can...

journal_title：Journal of Cancer

authors： Zhang J,Yang X,Wei L,Tan H,Chen J,Li W,Chan K,Su Y,Zhao L,Hu S,Zhong S,Xiao Y,Liu H

更新日期：2020-09-17 00:00:00

abstract：:Background: Radiotherapy is a standard treatment for a significant fraction of cancer patients. Nonetheless, to this day radiation resistance is a key impediment in gastric cancer (GC) treatment. Moreover, GC is characterized by its substantial neo-angiogenesis, driven by high levels of vascular endothelial growth fac...

journal_title：Journal of Cancer

authors： Li G,Lin H,Tian R,Zhao P,Huang Y,Pang X,Zhao L,Cao B

更新日期：2018-10-18 00:00:00

abstract：:Hepatocellular Carcinoma is a major healthcare problem, representing the third most common cause of cancer-related mortality worldwide. There are 130 million Hepatitis C virus infected patients worldwide who are at a high-risk for developing Hepatocellular Carcinoma. Due to the fact that reliable parameters and/or too...

journal_title：Journal of Cancer

authors： Abdalla MA,Haj-Ahmad Y

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:MALAT-1 is significantly overexpressed in various cancers, suggesting that it might be a potential biomarker of cancer. METHODS:A meta-analysis was performed using microarray data obtained via the Affymetrix Human Genome U133 Plus 2.0 platform found in the Gene Expression Omnibus (GEO) database and data obt...

journal_title：Journal of Cancer

authors： Wang Y,Xue D,Li Y,Pan X,Zhang X,Kuang B,Zhou M,Li X,Xiong W,Li G,Zeng Z,Yang T

更新日期：2016-05-20 00:00:00

abstract：:Background & Aims: Primary tumors of colorectal carcinoma (CRC) with liver metastasis might gain some liver-specific characteristics to adapt the liver micro-environment. This study aims to reveal potential liver-like transcriptional characteristics associated with the liver metastasis in primary colorectal carcinoma....

journal_title：Journal of Cancer

authors： Cheng J,Song X,Ao L,Chen R,Chi M,Guo Y,Zhang J,Li H,Zhao W,Guo Z,Wang X

更新日期：2018-04-06 00:00:00

abstract：:Background and aims. Cyclin-dependent kinase inhibitor 3 (CDKN3) has been found playing a varying role in carcinogenesis, but its biological function in esophageal squamous cell carcinoma (ESCC) is unclear. The aim of this study was to demonstrate the role of CDKN3 in ESCC. Materials and Methods: Real-time PCR and Wes...

journal_title：Journal of Cancer

authors： Liu J,Min L,Zhu S,Guo Q,Li H,Zhang Z,Zhao Y,Xu C,Zhang S

更新日期：2019-04-21 00:00:00

abstract：:Many preclinical and clinical studies are currently evaluating metformin in combination with classical therapeutic agents as anti-cancer therapy. In this study we used three distinct pancreatic cancer cell lines and evaluated cell death by trypan blue assay and Western Blots using antibodies directed against cleaved c...

journal_title：Journal of Cancer

authors： Zechner D,Albert AC,Bürtin F,Vollmar B

更新日期：2017-07-01 00:00:00

abstract：:Ovarian cancer, cervical cancer and endometrial cancer are three relatively common malignant cancers of the female reproductive system. Despite improvements in female genital tract cancer detection and development of new therapeutic approaches, there are still poor prognoses and some do not respond to therapeutic patt...

journal_title：Journal of Cancer

authors： Zhu DL,Tuo XM,Rong Y,Zhang K,Guo Y

更新日期：2020-10-21 00:00:00

abstract：:Hepatocellular carcinoma (HCC) cells exhibit multidrug resistance (MDR), but the underlying mechanisms remain unclear. Cancer cells that overexpress telomerase are resistant to chemotherapeutic drugs. This study aimed to determine the effects of mitochondrial translocation of telomerase on MDR in HCC cells. HepG2 cell...

journal_title：Journal of Cancer

authors： Yan J,Zhou Y,Chen D,Li L,Yang X,You Y,Ling X

更新日期：2015-01-05 00:00:00

abstract：:Many studies, using different chemical agents, have shown excellent cancer prevention efficacy in mice and rats. However, equivalent tests of cancer prevention in humans require decades of intake of the agents while the rodents' short lifespans cannot give us information of the long-term safety. Therefore, animals wit...

journal_title：Journal of Cancer

authors： Ma Y,Jia Y,Chen L,Ezeogu L,Yu B,Xu N,Liao DJ

更新日期：2015-09-01 00:00:00

abstract：:Amplified in breast cancer 1 (AIB1) gene, a coactivator for steroid receptor, is frequently amplified in diverse cancers and is considered as an oncogene in tumorigenesis. However, the prognostic significance of AIB1 amplification in gliomas remains totally unclear. In this study, 115 gliomas and 16 benign meningiomas...

journal_title：Journal of Cancer

authors： Chen L,Wang C,Zhang X,Gao K,Liu R,Shi B,Hou P

更新日期：2016-10-22 00:00:00

abstract：:Clinical studies have confirmed epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors (TKIs) used in lung cancer patients with EGFR mutations can obtain a better result, but still part of the patients with poor efficacy. EGFR mutation is highly related to female, nonsmoking and adenocarcinoma. Thus, we hy...

journal_title：Journal of Cancer

authors： Yin ZJ,Tu HY,Fu M,Zhong WZ,An SJ,Yan HH,Chen HJ,Lin HR,Wu YL

更新日期：2018-07-30 00:00:00

abstract：INTRODUCTION:Cyclin D1 (D1) binds to cyclin-dependent kinases (CDK) 4 or 6 to form a holoenzyme that phosphorylates the Rb protein to promote cell cycle progression from G1 to S phase. Therefore, targeting CDK4/6 may be a good strategy for chemotherapy of cancer. We performed a proof-of-principle study to determine the...

journal_title：Journal of Cancer

authors： Sun Y,Li YX,Wu HJ,Wu SH,Wang YA,Luo DZ,Liao DJ

更新日期：2011-01-08 00:00:00

abstract：:Background: To investigate the relationship between clinical and histopathological characteristics and overall survival of patients with oral mucosal melanoma (OMM) without distal metastasis in order to provide predictive prognostic information of OMM. Methods: Ki67 expression was assessed by immunohistochemistry in 1...

journal_title：Journal of Cancer

authors： Ma X,Wu Y,Zhang T,Song H,Jv H,Guo W,Ren G

更新日期：2017-10-17 00:00:00

abstract：:Background: Docetaxel (DOC), or Taxotere, is an anthracycline antibiotic used to treat multiple types of cancer. It is a first-line chemotherapy treatment for patients with metastasized, hormone-resistant prostate cancer (PCa) or for patients with high-risk, localized PCa that could benefit from early chemotherapy tre...

journal_title：Journal of Cancer

authors： Mansour M,van Ginkel S,Dennis JC,Mason B,Elhussin I,Abbott K,Pondugula SR,Samuel T,Morrison E

更新日期：2018-11-11 00:00:00

abstract：:Background: While curative resection is the established strategy for Hepatocellular carcinoma (HCC) patients, the prognosis still remains poor, and the efficiency of existing prediction models is unsatisfactory. Therefore, we aimed to develop a credible and easy-to-use prognostic index for patients with HCC undergoing...

journal_title：Journal of Cancer

authors： Gan W,Yi Y,Fu Y,Huang J,Lu Z,Jing C,Fan J,Zhou J,Qiu S

更新日期：2018-01-01 00:00:00

abstract：:Objectives: To investigate the role of inflammation-related factors, lymphocyte-to-monocyte ratio (LMR) alone and combined detection with cancer antigen 125 (CA125), in the prognostic assessment of ovarian cancer (OC). Methods: A retrospective clinicopathologic review was performed. The receiver-operating characterist...

journal_title：Journal of Cancer

authors： Tang Y,Hu HQ,Tang FX,Lin D,Shen R,Deng L,Tang YL,Deng LH,Zhou M,Li J,Su B,Xu F

更新日期：2020-03-04 00:00:00

abstract：:Purpose: We explored the influence of age on clinicopathologic features and survival of patients with M0 gastric cancer (GC). Methods: 16856 GC patients from Surveillance, Epidemiology and End Results (SEER) database and 1037 GC patients from Chinese multiple centers were enrolled in the U.S. and Chinese cohort, respe...

journal_title：Journal of Cancer

authors： Zhang J,Gan L,Xu MD,Huang M,Zhang X,Gong Y,Wang X,Yu G,Guo W

更新日期：2018-03-08 00:00:00

abstract：:Tripartite motif-containing 67 (TRIM67), an E3 ubiquitin ligase, belongs to the TRIM protein family. The relationship between TRIM67 and tumorigenesis is not fully clear. Here, we elucidated TRIM67 function in non-small cell lung cancer (NSCLC). TRIM67 immunostaining results were correlated with clinicopathological fe...

journal_title：Journal of Cancer

authors： Jiang J,Ren H,Xu Y,Wudu M,Wang Q,Liu Z,Su H,Jiang X,Zhang Y,Zhang B,Qiu X

更新日期：2020-01-01 00:00:00

abstract：PURPOSE:Methotrexate, vinblastine, doxorubicin plus cisplatin (MVAC) and gemcitabine plus cisplatin (GC) are both effective first-line chemotherapy. We explore the responsive variables of MVAC and GC for patients with metastatic urothelial carcinoma of bladder (mUCB). MATERIALS AND METHODS:Patients who were initially ...

journal_title：Journal of Cancer

authors： Hsieh MC,Huang CH,Chiang PH,Chen YY,Tang Y,Su YL

更新日期：2016-06-27 00:00:00

abstract：:Background: Integrative oncology (IO) is a relatively new field that seeks to bring evidence-based, non-conventional approaches into conventional oncology care in a coordinated and safe manner. Though complementary and alternative medicine (CAM) are highly utilized by cancer patients, little is known about the charact...

journal_title：Journal of Cancer

authors： Lopez G,McQuade J,Cohen L,Williams JT,Spelman AR,Fellman B,Li Y,Bruera E,Lee RT

更新日期：2017-02-10 00:00:00

abstract：:For unresectable Hepatocellular carcinoma (HCC), chemotherapy is still an important treatment strategy. Oxaliplatin (Oxa) is an effective treatment of HCC after sorafenib treatment failure. However, the intrinsic or acquired resistance of Oxa affected the chemotherapeutic sensitivity. By analyzing the data of GEO Data...

journal_title：Journal of Cancer

authors： Tao Y,Shan L,Xu X,Jiang H,Chen R,Qian Z,Yang Z,Liang B,Zheng H,Cai F,Yu Y,Ma L

更新日期：2018-10-10 00:00:00

abstract：:Purpose: Eukaryotic initiation factor 4A-3 (EIF4A3) is an RNA-binding protein (RBP) that is a core component of the exon junction complex (EJC). It has been identified as an important player in post-transcriptional regulation processes. Recently, investigations have focused on EIF4A3 dysfunction in carcinogenesis. The...

journal_title：Journal of Cancer

authors： Lin Y,Zhang J,Cai J,Liang R,Chen G,Qin G,Han X,Yuan C,Liu Z,Li Y,Zou D,Mao Y

更新日期：2018-11-11 00:00:00

abstract：:Multidrug resistance is a major obstacle to the effective treatment of esophageal carcinoma. It occurs more readily in hypoxia and acidosis microenvironment. TTLL6 is one of Tubulin tyrosine ligase-like family members. In this study, the effect of TTLL6 on the regulation of cisplatin (CDDP) sensitivity was evaluated i...

journal_title：Journal of Cancer

authors： Qiu Y,Wu C,Li J,Tang M,Zhang S,Jing T,Liao Y,Wang H

更新日期：2020-09-30 00:00:00

abstract：:Background: To support cancer therapy, development of low cost library preparation techniques for targeted next generation sequencing (NGS) is needed. In this study we designed and tested a PCR-based library preparation panel with limited target area for sequencing the top 12 somatic mutation hot spots in colorectal c...

journal_title：Journal of Cancer

authors： Péterfia B,Kalmár A,Patai ÁV,Csabai I,Bodor A,Micsik T,Wichmann B,Egedi K,Hollósi P,Kovalszky I,Tulassay Z,Molnár B

更新日期：2017-01-12 00:00:00

abstract：:Background and Aim: Glioblastoma multiforme (GBM) is a highly aggressive brain malignancy that lacks reliable treatments. Resveratrol possesses anti-cancer effects, but its activity against glioblastoma cells is variable for unknown reasons. One mechanism through which anti-cancer drugs exert their effects is oxidativ...

journal_title：Journal of Cancer

authors： Jia B,Zheng X,Wu ML,Tian XT,Song X,Liu YN,Li PN,Liu J

更新日期：2021-01-01 00:00:00

abstract：:Background: Topoisomerase IIA (TOP2A) gene encodes DNA topoisomerase enzyme and has been reported that TOP2A is broadly expressed in many types of cancers. Our study aims to investigate the prognostic effect of TOP2A on lung adenocarcinoma (LUAD) and the potential molecular mechanism of TOP2A to tumorigenesis. Methods...

journal_title：Journal of Cancer

authors： Kou F,Sun H,Wu L,Li B,Zhang B,Wang X,Yang L

更新日期：2020-02-10 00:00:00

abstract：PURPOSE:Triple-negative breast cancer (TNBC) has attracted more attention both clinically and experimentally because of its high-risk biological characteristics and lacking of effective treatment method. The purpose of this retrospective study was to find out the incidence of triple-negative breast cancer (TNBC) in all...

journal_title：Journal of Cancer

authors： Qiu J,Xue X,Hu C,Xu H,Kou D,Li R,Li M

更新日期：2016-01-01 00:00:00

abstract：:Background: We previously demonstrated that Proline rich 11 (PRR11) gene is associated with the development and progression of tongue squamous cell carcinoma (TSCC), but the underlying mechanism is unknown. This study aimed to investigate the molecular mechanism underlying oncogenic potential of PRR11 in TSCC cells. M...

journal_title：Journal of Cancer

authors： Wang C,Yu L,Ren X,Wu T,Chen X,Huang Y,Cheng B

更新日期：2019-06-02 00:00:00