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A Comparison of Optical, Electrochemical, Magnetic, and Colorimetric Point-of-Care Biosensors for Infectious Disease Diagnosis.

Abstract：

:Each year, infectious diseases are responsible for millions of deaths, most of which occur in the rural areas of developing countries. Many of the infectious disease diagnostic tools used today require a great deal of time, a laboratory setting, and trained personnel. Due to this, the need for effective point-of-care (POC) diagnostic tools is greatly increasing with an emphasis on affordability, portability, sensitivity, specificity, timeliness, and ease of use. In this Review, we discuss the various diagnostic modalities that have been utilized toward this end and are being further developed to create POC diagnostic technologies, and we focus on potential effectiveness in resource-limited settings. The main modalities discussed herein are optical-, electrochemical-, magnetic-, and colorimetric-based modalities utilized in diagnostic technologies for infectious diseases. Each of these modalities feature pros and cons when considering application in POC settings but, overall, reveal a promising outlook for the future of this field of technological development.

journal_name

ACS Infect Dis

journal_title

ACS infectious diseases

authors

Pashchenko O,Shelby T,Banerjee T,Santra S

doi

10.1021/acsinfecdis.8b00023

subject

Has Abstract

pub_date

2018-08-10 00:00:00

pages

1162-1178

issue

8

issn

2373-8227

journal_volume

4

pub_type

杂志文章,评审

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