Symptomatic Acute Toxoplasmosis in Returning Travelers.

abstract：Background:Dengue and Chikungunya viruses can cause large-scale epidemics, with attack rates of up to 80%. In Tanzania, there have been repeated outbreaks of dengue fever, the most recent in 2018 and 2019, mostly affecting the coastal areas. Despite the importance of these viruses, there is limited knowledge on the epi...

journal_title：Open forum infectious diseases

authors： Chipwaza B,Sumaye RD,Weisser M,Gingo W,Yeo NK,Amrun SN,Okumu FO,Ng LFP

更新日期：2020-12-26 00:00:00

abstract：Background:Human babesiosis is a common zoonosis caused by Babesia and is attracting an increasing concern worldwide. The natural course of babesiosis infection and how the human immune system changes during the course of babesiosis infection are not clear. Methods:We followed up 1 case infected with Babesia venatorum...

journal_title：Open forum infectious diseases

authors： Zhao L,Jiang R,Jia N,Ning N,Zheng Y,Huo Q,Sun Y,Yuan T,Jiang B,Li T,Liu H,Liu X,Chu Y,Wei R,Bian C,Wang H,Song J,Wang H,Jiang J,Cao W

更新日期：2020-02-18 00:00:00

abstract：BACKGROUND:Invasive aspergillosis (IA) and mucormycosis contribute to substantial mortality, especially among immunocompromised persons, including those with hematopoietic stem cell transplant (HSCT), hematologic malignancy (HM), and solid organ transplant (SOT). METHODS:Using International Classification of Diseases,...

journal_title：Open forum infectious diseases

authors： Vallabhaneni S,Benedict K,Derado G,Mody RK

更新日期：2017-01-13 00:00:00

abstract：BACKGROUND:Because hospitals in a region are connected via patient sharing, a norovirus outbreak in one hospital may spread to others. METHODS:We utilized our Regional Healthcare Ecosystem Analyst software to generate an agent-based model of all the acute care facilities in Orange County (OC), California and simulated...

journal_title：Open forum infectious diseases

authors： Bartsch SM,Huang SS,Wong KF,Avery TR,Lee BY

更新日期：2014-07-02 00:00:00

abstract：:Background.  The majority of Lyme disease cases in the United States are acquired on the east coast between northern Virginia and New England. In recent years the geographic extent of Lyme disease has been expanding, raising the prospect of Lyme disease becoming endemic in the southeast. Methods.  We collected confirm...

journal_title：Open forum infectious diseases

authors： Lantos PM,Nigrovic LE,Auwaerter PG,Fowler VG Jr,Ruffin F,Brinkerhoff RJ,Reber J,Williams C,Broyhill J,Pan WK,Gaines DN

更新日期：2015-09-27 00:00:00

abstract：:Symptomatic acute HCV infection and interferon lambda 4 (IFNL4) genotypes are important predictors of spontaneous viral clearance. Using data from a multicohort database (Injecting Cohorts [InC3] Collaborative), we establish an independent association between host IFNL4 genotype and symptoms of acute hepatitis C virus...

journal_title：Open forum infectious diseases

authors： Page K,Mirzazadeh A,Rice TM,Grebely J,Kim AY,Cox AL,Morris MD,Hellard M,Bruneau J,Shoukry NH,Dore GJ,Maher L,Lloyd AR,Lauer G,Prins M,McGovern BH

更新日期：2016-02-08 00:00:00

abstract：Background:Delayed pathogen identification and nonspecific clinical findings make definitive decisions regarding antibiotics challenging. The stimuli of bacterial toxins and inflammation make procalcitonin (PCT) unique in its ability to differentiate bacterial infection from other causes of inflammation, and thus it is...

journal_title：Open forum infectious diseases

authors： Broyles MR

更新日期：2017-10-03 00:00:00

abstract：:Community-onset bacteremic Acinetobacter baumannii pneumonia recurred in 3 of 30 (10%) patients followed prospectively, all with ongoing hazardous alcohol intake, 3-56 months after initial pneumonia. Paired isolates underwent whole-genome sequencing. Phylogenetic analysis showed that recurrence strains were all distin...

journal_title：Open forum infectious diseases

authors： Meumann EM,Anstey NM,Currie BJ,Piera KA,Baird R,Sarovich DS,Davis JS

更新日期：2019-06-01 00:00:00

abstract：Background:Health departments utilize HIV surveillance data to identify people with HIV (PWH) who need re-linkage to HIV care as part of an approach known as Data to Care (D2C.) The most accurate, effective, and efficient method of identifying PWH for re-linkage is unknown. Methods:We evaluated referral and care conti...

journal_title：Open forum infectious diseases

authors： Sachdev DD,Mara E,Hughes AJ,Antunez E,Kohn R,Cohen S,Scheer S

更新日期：2020-08-21 00:00:00

abstract：:This study evaluated health outcomes among people who inject drugs who are infected with hepatitis C virus using an artificial intelligence platform. Mean (SD) cumulative adherence (visual confirmation of administration) was 91.3% (10.5%). Most subjects (88.2%) achieved ≥80% adherence to treatment, and 88.2% (15 of 17...

journal_title：Open forum infectious diseases

authors： Litwin AH,Shafner L,Norton B,Akiyama MJ,Agyemang L,Guzman M,Vera T,Heo M

更新日期：2020-07-20 00:00:00

abstract：:Using data from 3 private healthcare claims repositories, we evaluated the incidence of pneumococcal disease among adults with US Advisory Committee on Immunization Practices (ACIP) defined at-risk conditions or rheumatoid arthritis, lupus, Crohn's disease, and neuromuscular disorder/seizures and those with traditiona...

journal_title：Open forum infectious diseases

authors： Pelton SI,Shea KM,Weycker D,Farkouh RA,Strutton DR,Edelsberg J

更新日期：2015-03-20 00:00:00

abstract：Background:The number of invasive group A Streptococcus (iGAS) infections due to hitherto extremely rare type emm74 strains has increased in several Canadian provinces since late 2015. We hypothesized that the cases recorded in the different provinces are linked and caused by strains of an emm74 clone that recently eme...

journal_title：Open forum infectious diseases

authors： Teatero S,McGeer A,Tyrrell GJ,Hoang L,Smadi H,Domingo MC,Levett PN,Finkelstein M,Dewar K,Plevneshi A,Athey TBT,Gubbay JB,Mulvey MR,Martin I,Demczuk W,Fittipaldi N

更新日期：2018-04-20 00:00:00

abstract：:People living with human immunodeficiency virus frequently use dietary supplements, including probiotics, but concern exists about ingesting live organisms. We performed a systematic review of the benefits of probiotics and a meta-analysis of sepsis risk. We undertook a protocol-driven, comprehensive review to identif...

journal_title：Open forum infectious diseases

authors： Carter GM,Esmaeili A,Shah H,Indyk D,Johnson M,Andreae M,Sacks HS

更新日期：2016-07-29 00:00:00

abstract：Background:Patients heterozygous for mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene may be more susceptible to respiratory infections than the general population. Methods :We conducted a retrospective case-control study using health insurance claims. We identified patients as either h...

journal_title：Open forum infectious diseases

authors： Polgreen PM,Brown GD,Hornick DB,Ahmad F,London B,Stoltz DA,Comellas AP

更新日期：2018-11-01 00:00:00

abstract：:Skin and soft tissue infections (SSTI) affect millions of people globally, which represents a significant burden on ambulatory care and hospital settings. The role of sulfamethoxazole-trimethoprim (SXT) in SSTI treatment, particularly when group A Streptococcus (GAS) is involved, is controversial. We conducted a syste...

journal_title：Open forum infectious diseases

authors： Bowen AC,Carapetis JR,Currie BJ,Fowler V Jr,Chambers HF,Tong SYC

更新日期：2017-11-02 00:00:00

abstract：BACKGROUND:Antiretroviral therapy (ART) is recommended for all people living with human immunodeficiency virus (HIV), yet physician attitudes and prescribing behaviors toward members of key risk populations may limit ART access and undermine treatment as prevention strategies. METHODS:Physicians in Malaysia (N = 214) ...

journal_title：Open forum infectious diseases

authors： Ferro EG,Culbert GJ,Wickersham JA,Marcus R,Steffen AD,Pauls HA,Westergaard RP,Lee CK,Kamarulzaman A,Altice FL

更新日期：2017-01-25 00:00:00

abstract：:Methods.  In a cross-sectional substudy of the Multicenter AIDS Cohort Study, noncontrast cardiac computed tomography (CT) scanning for coronary artery calcium (CAC) scoring was performed on all men, and, for men with normal renal function, coronary CT angiography (CTA) was performed. Associations between fat depots (...

journal_title：Open forum infectious diseases

authors： Palella FJ Jr,McKibben R,Post WS,Li X,Budoff M,Kingsley L,Witt MD,Jacobson LP,Brown TT

更新日期：2016-06-16 00:00:00

abstract：Background:This study investigates the association of clinical and demographic predictors with abdominal fat gain, measured using waist circumference (WC) and self-reported abdominal size. Methods:We analyzed data from ACTG A5257, a clinical trial that randomized treatment-naïve HIV-infected participants to 1 of 3 ant...

journal_title：Open forum infectious diseases

authors： Bhagwat P,Ofotokun I,McComsey GA,Brown TT,Moser C,Sugar CA,Currier JS

更新日期：2018-11-16 00:00:00

abstract：:Cryptococcus gattii represents an emerging fungal pathogen of immunocompromised and immunocompetent hosts in the United States. To our knowledge, this is the first case of posttransplant immune reconstitution syndrome due to C. gattii meningoencephalitis successfully treated with corticosteroids. We also report succes...

journal_title：Open forum infectious diseases

authors： Canfield GS,Henao-Martínez AF,Franco-Paredes C,Zhelnin K,Wilson ML,Shihadeh KC,Wyles D,Gardner EM

更新日期：2019-10-23 00:00:00

abstract：:This is a single-center retrospective observational cohort study comparing daptomycin/ceftaroline combination therapy with rifampin-adjunct therapy for the treatment of staphylococcal device infections. The results of this study support use of the daptomycin/ceftaroline as an alternative or salvage option to standard ...

journal_title：Open forum infectious diseases

authors： Chang AT,Cosimi RA,Bochan MR

更新日期：2020-02-28 00:00:00

abstract：:Vancomycin is commonly added as empiric therapy for febrile neutropenia. A retrospective chart review was conducted at a large community teaching institution to evaluate vancomycin use in oncology patients. The results revealed that a majority of empiric vancomycin therapy was inappropriate, raising concern for antibi...

journal_title：Open forum infectious diseases

authors： Libuit J,Whitman A,Wolfe R,Washington CS

更新日期：2014-04-10 00:00:00

abstract：Background:Irritable bowel syndrome (IBS) is a chronic and debilitating functional gastrointestinal disorder affecting 9%-23% of the population across the world. The relative efficacy of fecal microbiota transplantation (FMT) on IBS symptoms was demonstrated in a double-blind, randomized study. Methods:We describe the...

journal_title：Open forum infectious diseases

authors： Hocquart M,Pham T,Kuete E,Tomei E,Lagier JC,Raoult D

更新日期：2019-10-14 00:00:00

abstract：:The spectrum of West Nile virus (WNV) infection continues to be elucidated. Many cases of WNV are asymptomatic; however, in immunocompromised patients, symptoms are more likely to be severe. We describe fatal WNV central nervous system disease in lymphoma patients who received rituximab, blunting the inflammatory resp...

journal_title：Open forum infectious diseases

authors： Morjaria S,Arguello E,Taur Y,Sepkowitz K,Hatzoglou V,Nemade A,Rosenblum M,Cavalcanti MS,Palomba ML,Kaltsas A

更新日期：2015-09-19 00:00:00

abstract：Background:Plasma gelsolin (pGSN) is an abundant circulating protein quickly consumed by extensive tissue damage. Marked depletion is associated with later poor outcomes in diverse clinical circumstances. Repletion with recombinant human (rhu)-pGSN in animal models of inflammation lessens mortality and morbidity. Meth...

journal_title：Open forum infectious diseases

authors： DiNubile MJ,Levinson SL,Stossel TP,Lawrenz MB,Warawa JM

更新日期：2020-06-19 00:00:00

abstract：:Microvascular function and oxygen consumption affect oxygen homeostasis but have not been assessed in African children with malaria. Microvascular function in Tanzanian children with severe malaria (SM) or uncomplicated malaria were 39% and 72%, respectively, of controls (P < .001). Uncomplicated malaria (P = .04), no...

journal_title：Open forum infectious diseases

authors： Yeo TW,Florence SM,Kalingonji AR,Chen Y,Granger DL,Anstey NM,Mwaikambo ED,Weinberg JB

更新日期：2017-04-22 00:00:00

abstract：:This report describes a case of relapsing pneumococcal peritonitis. The postulated source of infection was vaginal colonization and secondary adherence of pneumococci to an intrauterine contraceptive device. After immunization with a conjugate pneumococcal vaccine, her antibody levels were observed. She remained infec...

journal_title：Open forum infectious diseases

authors： Sendi P,Moser Schaub EM,Nirgianakis K,Hathaway LJ,Bittel P,Goldblatt D,Streit S

更新日期：2016-12-07 00:00:00

abstract：Background:US hematopoietic cell transplantation (HCT) recipients have a low prevalence of latent tuberculosis infection (LTBI), but if latently infected they are at risk for progression to active tuberculosis. At our center, all HCT recipients underwent LTBI testing pretransplant by tuberculin skin testing (TST) until...

journal_title：Open forum infectious diseases

authors： Sosa-Moreno A,Narita M,Spitters C,Swetky M,Podczervinski S,Lind ML,Holmberg L,Liu C,Edelstein R,Pergam SA

更新日期：2020-06-10 00:00:00

abstract：:Surveillance represents an important informational tool for planning actions to monitor emerging antimicrobial resistance. Antimicrobial resistance surveillance (ARS) programs may have many different designs and can be grouped in 2 major categories based on their main objectives: (1) public health ARS programs and (2)...

journal_title：Open forum infectious diseases

authors： Sader HS,Rhomberg PR,Fuhrmeister AS,Mendes RE,Flamm RK,Jones RN

更新日期：2019-03-15 00:00:00

abstract：BACKGROUND:Ombitasvir, paritaprevir with ritonavir, and dasabuvir (OBV/PTV/r ± DSV) ±ribavirin (RBV) are approved to treat hepatitis C virus (HCV) genotype 1 and 4 infection. Here, we investigate the safety and efficacy of OBV/PTV/r + DSV ±RBV for HCV genotype 1, and OBV/PTV/r + RBV for HCV genotype 4, in human immunod...

journal_title：Open forum infectious diseases

authors： Rockstroh JK,Orkin C,Viani RM,Wyles D,Luetkemeyer AF,Lazzarin A,Soto-Malave R,Nelson MR,Bhagani SR,Klinker HHF,Rizzardini G,Girard PM,Tural C,Shulman NS,Mobashery N,Hu YB,Fredrick LM,Pilot-Matias T,Trinh R,Gane E

更新日期：2017-07-22 00:00:00

abstract：BACKGROUND:Postoperative infections are a common and often preventable complication of surgery. S. aureus is a prevalent organism cultured in these infections and is associated with morbidity, mortality, and increased healthcare utilization. However, the long-term burden of S. aureus infection in surgical patients is n...

journal_title：Open forum infectious diseases

authors： O'Brien WJ,Gupta K,Itani KMF

更新日期：2019-08-13 00:00:00