Transport and Mixing Induced by Beating Cilia in Human Airways.

abstract：Background:Perturbation of endothelial function in people with cystic fibrosis (CF) has been reported, which may be associated with endothelial cell expression of the cystic fibrosis transmembrane conductance regulator (CFTR). Previous reports indicate that CFTR activity upregulates endothelial barrier function, endoth...

journal_title：Frontiers in physiology

authors： Khalaf M,Scott-Ward T,Causer A,Saynor Z,Shepherd A,Górecki D,Lewis A,Laight D,Shute J

更新日期：2020-07-29 00:00:00

abstract：:Respiratory/inspiratory muscle training (RMT/IMT) has been proposed to improve the endurance performance of athletes in normoxia. In recent years, due to the increased use of hypoxic training method among athletes, the RMT applicability has also been tested as a method to minimize adverse effects since hyperventilatio...

journal_title：Frontiers in physiology

authors： Álvarez-Herms J,Julià-Sánchez S,Corbi F,Odriozola-Martínez A,Burtscher M

更新日期：2019-01-15 00:00:00

abstract：:Characterization of flow properties in cerebral arteries with 1.5 and 3 Tesla MRI is usually limited to large cerebral arteries and difficult to evaluate in the small perforating arteries due to insufficient spatial resolution. In this study, we assessed the feasibility to measure blood flow waveforms in the small len...

journal_title：Frontiers in physiology

authors： Schnerr RS,Jansen JFA,Uludag K,Hofman PAM,Wildberger JE,van Oostenbrugge RJ,Backes WH

更新日期：2017-11-24 00:00:00

abstract：:It is known that circulating angiotensin II (ANG-II) acts on the circumventricular organs (CVOs), which partially lack a normal blood-brain barrier, to stimulate pressor responses, vasopressin (AVP), and oxytocin (OT) secretion, as well as sodium and water intake. Although ANG-II type 1 receptors (AT1R) are expressed ...

journal_title：Frontiers in physiology

authors： Flôr AFL,de Brito Alves JL,França-Silva MS,Balarini CM,Elias LLK,Ruginsk SG,Antunes-Rodrigues J,Braga VA,Cruz JC

更新日期：2018-05-01 00:00:00

abstract：Objectives:Carotid artery geometry influences blood flow disturbances and is thus an important risk factor for carotid atherosclerosis. Extracellular matrix (ECM) and yes-associated protein (YAP) expression may play essential roles in the pathophysiology of carotid artery stenosis, but the effect of blood flow disturba...

journal_title：Frontiers in physiology

authors： Cui Y,Lv X,Wang F,Kong J,Zhao H,Ye Z,Si C,Pan L,Liu P,Wen J

更新日期：2020-01-21 00:00:00

abstract：:Patients undergoing the complex treatment for hematological malignancies are exposed to a high physiological and psychological distress inducing fatigue and physical inactivity. In line with cancer-related metabolic changes patients are predisposed for skeletal muscle mass loss that leads to a functional decline, affe...

journal_title：Frontiers in physiology

authors： Schink K,Reljic D,Herrmann HJ,Meyer J,Mackensen A,Neurath MF,Zopf Y

更新日期：2018-12-18 00:00:00

abstract：:Maternal over- and restricted-feeding during gestation have similar negative consequences for the offspring, including decreased muscularity, increased adiposity, and altered metabolism. Our objective was to determine the effects of poor maternal nutrition during gestation (over- and restricted-feeding) on the offspri...

journal_title：Frontiers in physiology

authors： Martin DE,Jones AK,Pillai SM,Hoffman ML,McFadden KK,Zinn SA,Govoni KE,Reed SA

更新日期：2019-05-01 00:00:00

abstract：:Molecular imaging has emerged in the past few decades as a novel means to investigate atherosclerosis. From a pathophysiological perspective, atherosclerosis is characterized by microscopic inflammation and microcalcification that precede the characteristic plaque buildup in arterial walls detected by traditional asse...

journal_title：Frontiers in physiology

authors： Mayer M,Borja AJ,Hancin EC,Auslander T,Revheim ME,Moghbel MC,Werner TJ,Alavi A,Rajapakse CS

更新日期：2020-10-22 00:00:00

abstract：:The rice-fish mode, a mode of ecological aquaculture, has become a popular research topic in recent years. The antioxidant capacity of fish can be affected by the type of diet. Three groups of adult common carp (initial weight 517.8 ± 50 g) were fed earthworm (group A), earthworm + duckweed (group M), and duckweed (gr...

journal_title：Frontiers in physiology

authors： Yang S,Luo J,Long Y,Du J,Xu G,Zhao L,Du Z,Luo W,Wang Y,He Z

更新日期：2019-05-29 00:00:00

abstract：:Background and Purpose: Store-operated calcium entry (SOCE) is an important physiological phenomenon that extensively mediates intracellular calcium ion (Ca2+) load. It has been previously found in myocytes isolated from neonatal or diseased hearts. We aimed to determine its existence, molecular nature in undiseased h...

journal_title：Frontiers in physiology

authors： Wen H,Zhao Z,Fefelova N,Xie LH

更新日期：2018-12-13 00:00:00

abstract：:Red blood cell (RBC) deformability is an important determinant of the microcirculation. It is influenced by various hematological parameters but also by nitric oxide (NO) which is produced in RBC from L-arginine by RBC-NO synthase. Longitudinal studies on blood profile, deformability at rest and NO levels but also dif...

journal_title：Frontiers in physiology

authors： Grau M,Cremer JM,Schmeichel S,Kunkel M,Bloch W

更新日期：2018-12-19 00:00:00

abstract：:Purpose: To provide insights into the energy requirements as well as the physiological adaptations of an experienced 50-year-old ultra-marathon male athlete during the world's most challenging mountain ultra-marathon (MUM). Methods: The international race supporting the study was the Tor des Geants®, characterized by ...

journal_title：Frontiers in physiology

authors： Savoldelli A,Fornasiero A,Trabucchi P,Limonta E,La Torre A,Degache F,Pellegrini B,Millet GP,Vernillo G,Schena F

更新日期：2017-12-05 00:00:00

abstract：:Melanization reflects not only body color variation but also environmental plasticity. It is a strategy that helps insects adapt to environmental change. Different color morphs may have distinct life history traits, e.g., development time, growth rate, and body weight. The green slender planthopper Saccharosydne proce...

journal_title：Frontiers in physiology

authors： Yin H,Shi Q,Shakeel M,Kuang J,Li J

更新日期：2016-09-12 00:00:00

abstract：:Introduction: Tilt tables enable early mobilization of patients by providing verticalization. But there is a high risk of orthostatic hypotension provoked by verticalization, especially after neurological diseases such as spinal cord injury. Robot-assisted tilt tables might be an alternative as they add passive roboti...

journal_title：Frontiers in physiology

authors： Sarabadani Tafreshi A,Riener R,Klamroth-Marganska V

更新日期：2016-12-09 00:00:00

abstract：:The detailed behavior of many molecular processes in the cell, such as protein folding, protein complex assembly, and gene regulation, transcription and translation, can often be accurately captured by stochastic chemical kinetic models. We investigate a novel computational problem involving these models - that of fin...

journal_title：Frontiers in physiology

authors： Salehi M,Perkins TJ

更新日期：2010-10-19 00:00:00

abstract：:Reactive Oxygen Species (ROS) can cause oxidative damage and have been proposed to be the main cause of aging and age-related diseases including cancer, diabetes and Parkinson's disease. Accordingly, mitochondria from old individuals have higher levels of ROS. However, ROS also participate in cellular signaling, are i...

journal_title：Frontiers in physiology

authors： Scialò F,Fernández-Ayala DJ,Sanz A

更新日期：2017-06-27 00:00:00

abstract：:Purpose: To examine the effects of deceptively aggressive bike pacing on performance, pacing, and associated physiological and perceptual responses during simulated sprint-distance triathlon. Methods: Ten non-elite, competitive male triathletes completed three simulated sprint-distance triathlons (0.75 km swim, 500 kJ...

journal_title：Frontiers in physiology

authors： Taylor D,Smith MF

更新日期：2017-01-24 00:00:00

abstract：:Development of mammalian teeth and surrounding tissues includes time-space changes in the extracellular matrix composition and organization. This requires complex control mechanisms to regulate its synthesis and remodeling. Fibril-associated collagens with interrupted triple helices (FACITs) and a group of small leuci...

journal_title：Frontiers in physiology

authors： Zvackova I,Matalova E,Lesot H

更新日期：2017-08-02 00:00:00

abstract：:In Bombyx mori, polar body nuclei are observed until 9 h after egg lying, however, the fate of polar body nuclei remains unclear. To examine the fate of polar body nuclei, we employed a mutation of serosal cell pigmentation, pink-eyed white egg (pe). The heterozygous pe/+ (pe) females produced black serosal cells in w...

journal_title：Frontiers in physiology

authors： Sakai H,Yokoyama T,Abe H,Fujii T,Suzuki MG

更新日期：2013-09-03 00:00:00

abstract：:Anatomical evidence in several species shows highly heterogeneous fat distribution in the atrial and ventricular myocardium. Atrial appendages have fat deposits, and more so on the posterior left atrium. Although such fat distributions are considered normal, fatty infiltration is regarded arrhythmogenic, and various c...

journal_title：Frontiers in physiology

authors： Anumonwo JMB,Herron T

更新日期：2018-01-22 00:00:00

abstract：:Elderly healthy individuals have a reduced exercise tolerance and a decreased left ventricle inotropic reserve related to increased vascular afterload, arterial-ventricular load mismatching, physical deconditioning and impaired autonomic regulation (the so called "β-adrenergic desensitization"). Adrenergic responsiven...

journal_title：Frontiers in physiology

authors： Ferrara N,Komici K,Corbi G,Pagano G,Furgi G,Rengo C,Femminella GD,Leosco D,Bonaduce D

更新日期：2014-01-09 00:00:00

abstract：:When compared to the previous generations, younger generations have become sedentary on a global level. Physical activity positively contributes to human growth and development, causing, indeed, both physiological and psychological benefits. The aim of the current study was examining the relationship between physical ...

journal_title：Frontiers in physiology

authors： Padulo J,Bragazzi NL,De Giorgio A,Grgantov Z,Prato S,Ardigò LP

更新日期：2019-03-05 00:00:00

abstract：:Claudin-1 is a tight junction transmembrane protein. Its localization in the maturation ameloblasts of rat incisors was examined by immunofluorescence microscopy. Distal junction area of ruffle-ended ameloblasts (RA) and the Golgi apparatus of a sub-population of smooth-ended ameloblasts (SA) and RAs stained positive ...

journal_title：Frontiers in physiology

authors： Nishikawa S,Abe M

更新日期：2010-11-16 00:00:00

abstract：:The aim of this study was to examine the effects of Lactobacillus brevis on the microbial community and serum metabolome in colitis induced by dextran sulfate sodium (DSS). ICR mice were randomly distributed into three treatment groups: (i) L. brevis treatment alone (control), (ii) DSS administration alone, and (iii) ...

journal_title：Frontiers in physiology

authors： Ding S,Ma Y,Liu G,Yan W,Jiang H,Fang J

更新日期：2019-09-18 00:00:00

abstract：:The cell-division cycle (CDC) is driven by cyclin-dependent kinases (CDKs). Mathematical models based on molecular networks, as revealed by molecular and genetic studies, have reproduced the oscillatory behavior of CDK activity. Thus, one basic system for representing the CDC is a biochemical oscillator (CDK oscillato...

journal_title：Frontiers in physiology

authors： Arata Y,Takagi H

更新日期：2019-08-19 00:00:00

abstract：:Activation of autonomic neural pathways by chronic hypertensive stimuli plays a significant role in pathogenesis of hypertension. Here, we proposed that even a single acute hypertensive stimulus will activate neural and immune pathways that may be important in initiation of memory imprinting seen in chronic hypertensi...

journal_title：Frontiers in physiology

authors： Zubcevic J,Santisteban MM,Perez PD,Arocha R,Hiller H,Malphurs WL,Colon-Perez LM,Sharma RK,de Kloet A,Krause EG,Febo M,Raizada MK

更新日期：2017-08-31 00:00:00

abstract：:Severe muscle weakness concomitant with preferential depletion of myosin has been observed in several pathological conditions. Here, we used the steroid-denervation (S-D) rat model, which shows dramatic decrease in myosin content and force production, to test whether electrical stimulation (ES) treatment can prevent t...

journal_title：Frontiers in physiology

authors： Yamada T,Himori K,Tatebayashi D,Yamada R,Ashida Y,Imai T,Akatsuka M,Masuda Y,Kanzaki K,Watanabe D,Wada M,Westerblad H,Lanner JT

更新日期：2018-08-10 00:00:00

abstract：:Preterm birth complications are the leading cause of child death worldwide and a top global health priority. Among the survivors, the risk of life-long disabilities is high, including cerebral palsy and impairment of movement, cognition, and behavior. Understanding the molecular mechanisms of preterm brain injuries is...

journal_title：Frontiers in physiology

authors： Pregnolato S,Chakkarapani E,Isles AR,Luyt K

更新日期：2019-04-24 00:00:00

abstract：:In this paper we develop a novel mathematical model of the insulin-TOR-MAPK signaling network that controls growth. Most data on the properties of the insulin and MAPK signaling networks are static and the responses to experimental interventions, such as knockouts, overexpression, and hormonal input are typically repo...

journal_title：Frontiers in physiology

authors： Nijhout HF,Callier V

更新日期：2013-09-12 00:00:00

abstract：:A rich chapter in the history of insect endocrinology has focused on hormonal control of diapause, especially the major roles played by juvenile hormones (JHs), ecdysteroids, and the neuropeptides that govern JH and ecdysteroid synthesis. More recently, experiments with adult diapause in Drosophila melanogaster and th...

journal_title：Frontiers in physiology

authors： Sim C,Denlinger DL

更新日期：2013-07-22 00:00:00