Repeated Exposure to the "Spice" Cannabinoid JWH-018 Induces Tolerance and Enhances Responsiveness to 5-HT1A Receptor Stimulation in Male Rats.

abstract：BACKGROUND:Schizophreniform syndromes can be divided into primary forms from polygenic causes or secondary forms due to immunological, epileptiform, monogenic, or degenerative causes. Steroid-responsive encephalopathy associated with autoimmune thyroiditis (SREAT) is a secondary immunological form associated with incre...

journal_title：Frontiers in psychiatry

authors： Endres D,Perlov E,Riering AN,Maier V,Stich O,Dersch R,Venhoff N,Erny D,Mader I,Tebartz van Elst L

更新日期：2017-04-21 00:00:00

abstract：:Background: Individual placement and support (IPS) has proven to be effective for vocational outcomes in people with mental illness. The original concept of IPS requires temporally unlimited provision of support. Using limited placement budgets and investigating factors that predict their effectiveness may inform deci...

journal_title：Frontiers in psychiatry

authors： Rössler W,Ujeyl M,Kawohl W,Nordt C,Lasalvia A,Haker H,Hengartner MP

更新日期：2019-07-19 00:00:00

abstract：:Background: Recent models of eating disorders (EDs) have proposed social and emotional difficulties as key factors in the development and maintenance of the illness. While a number of studies have demonstrated difficulties in theory of mind and emotion recognition, little is known about empathic abilities in those wit...

journal_title：Frontiers in psychiatry

authors： Kerr-Gaffney J,Harrison A,Tchanturia K

更新日期：2019-03-04 00:00:00

abstract：:Major depressive disorder (MDD) is a very common stress-related mental disorder that carries a huge burden for affected patients and the society. It is associated with a high mortality that derives from suicidality and the development of serious medical conditions such as heart diseases, diabetes, and stroke. Although...

journal_title：Frontiers in psychiatry

authors： Menke A

更新日期：2019-02-28 00:00:00

abstract：:This protocol describes a study that will test the effectiveness of a 7-week non-clinical digital coaching intervention to promote self-control. The goal of the coaching is to support and guide people who are willing and motivated to improve their self-control with the help of the smartphone application MindHike. The ...

journal_title：Frontiers in psychiatry

authors： Allemand M,Keller L,Gmür B,Gehriger V,Oberholzer T,Stieger M

更新日期：2020-10-09 00:00:00

abstract：:Autism spectrum disorder (ASD) and schizophrenia (SZ) are heterogenous neurodevelopmental disorders that overlap in symptom presentation. The purpose of this study was to specify overlapping symptom domains and to identify symptoms that can reliably differentiate adults with ASD (n = 53), SZ (n = 39), and typical deve...

journal_title：Frontiers in psychiatry

authors： Trevisan DA,Foss-Feig JH,Naples AJ,Srihari V,Anticevic A,McPartland JC

更新日期：2020-06-11 00:00:00

abstract：Background:Past studies using the Bonn Scale for the Assessment of Basic Symptoms (hereafter, Bonn Scale) have shown that self-reported perceptual/cognitive disturbances reveal which persons have or will soon develop schizophrenia. Here, we focused specifically on the clinical value of self-reported visual perceptual a...

journal_title：Frontiers in psychiatry

authors： Keane BP,Cruz LN,Paterno D,Silverstein SM

更新日期：2018-03-12 00:00:00

abstract：PURPOSE:Excessive daytime sleepiness is highly prevalent in the general population, is the hallmark of narcolepsy, and is linked to significant morbidity. Clinical assessment of sleepiness remains challenging and the common objective multiple sleep latency test (MSLT) and subjective Epworth sleepiness scale (ESS) metho...

journal_title：Frontiers in psychiatry

authors： Prasad B,Choi YK,Weaver TE,Carley DW

更新日期：2011-06-07 00:00:00

abstract：:The number of people with dementia worldwide is expected to increase to approximately 1.3 billion in 2050. Almost 90% of patients diagnosed with dementia suffer from behavioral and psychological symptoms of dementia (BPSD). BPSD causes and risk factors are multiple and complex and can be responsible for hospitalizatio...

journal_title：Frontiers in psychiatry

authors： Soares WB,Silvestre IT,Lima AMO,de Almondes KM

更新日期：2020-09-15 00:00:00

abstract：:Previous work has demonstrated that goal-directed control of alcohol-seeking and other drug-related behaviors is reduced following extended self-administration and drug exposure. Here, we examined how the magnitude of stimulus influences on responding changes across similar training and drug exposure. Rats self-admini...

journal_title：Frontiers in psychiatry

authors： Corbit LH,Janak PH

更新日期：2016-10-10 00:00:00

abstract：:Background: People with severe mental disorders (SMDs) have higher disease and death rates than the general population. Stigma (negative attitudes and perceptions) contributes to limited access to health services and a lower quality of medical assistance in this population, and it is manifested as negative attitudes, ...

journal_title：Frontiers in psychiatry

authors： Grandón P,Saldivia S,Vaccari P,Ramirez-Vielma R,Victoriano V,Zambrano C,Ortiz C,Cova F

更新日期：2019-03-07 00:00:00

abstract：Introduction:Although research over the past decade has resulted in significantly increased knowledge about distal risk factors for non-suicidal self-injury (NSSI), little is known about short-term (proximal) factors that predict NSSI thoughts and behaviors. Drawing on contemporaneous theories of NSSI, as well as the c...

journal_title：Frontiers in psychiatry

authors： Kiekens G,Hasking P,Nock MK,Boyes M,Kirtley O,Bruffaerts R,Myin-Germeys I,Claes L

更新日期：2020-03-20 00:00:00

abstract：:What is the role and value of pleasure in addiction? Foddy and Savulescu (1) have claimed that substance use is just pleasure-oriented behavior. They describe addiction as "strong appetites toward pleasure" and argue that addicts suffer in significant part because of strong social and moral disapproval of lives domina...

journal_title：Frontiers in psychiatry

authors： Kennett J,Matthews S,Snoek A

更新日期：2013-09-25 00:00:00

abstract：Objective:Employment was associated with recovery in individuals with schizophrenia. Our study aimed to delineate the vocational profile and investigate factors associated with likelihood of employment in individuals with schizophrenia. Materials and Methods:276 community dwelling outpatients with schizophrenia were r...

journal_title：Frontiers in psychiatry

authors： Ang MS,Rekhi G,Lee J

更新日期：2020-08-27 00:00:00

abstract：:In depression, brain and behavioral correlates of decision-making differ between individuals with and without suicidal thoughts and behaviors. Though promising, it remains unknown if these potential biomarkers of suicidality will generalize to other high-risk clinical populations. To preliminarily assess whether brain...

journal_title：Frontiers in psychiatry

authors： Barredo J,Aiken E,van 't Wout-Frank M,Greenberg BD,Carpenter LL,Philip NS

更新日期：2019-02-12 00:00:00

abstract：Background:Chronic insomnia is common in patients with arteriosclerotic cerebral small vessel disease (CSVD) and aggravates the cognitive impairment caused by CSVD. Low-dose trazodone is effective in treating insomnia, but it is unclear whether it can also improve cognitive function in CSVD patients. This study was per...

journal_title：Frontiers in psychiatry

authors： Wang J,Liu S,Zhao C,Han H,Chen X,Tao J,Lu Z

更新日期：2020-06-30 00:00:00

abstract：Background:Discharge from acute mental health services has long been associated with mortality, risk, and related adverse outcomes for patients. Many of the interventions that currently aim to reduce adverse outcomes focus on a single group of healthcare professionals within a single healthcare setting. A recent system...

journal_title：Frontiers in psychiatry

authors： Tyler N,Wright N,Grundy A,Gregoriou K,Campbell S,Waring J

更新日期：2020-04-21 00:00:00

abstract：:Molecular mechanisms in the brain are assumed to cause the symptoms and severity of neuropsychiatric disorders. This review concerns the elusive nature of relationships between the severity of depressive disorders and neuromolecular processes studied by positron emission tomography (PET). Recent PET studies of human d...

journal_title：Frontiers in psychiatry

authors： Smith DF,Jakobsen S

更新日期：2013-03-04 00:00:00

abstract：Background:Neuropsychological studies have revealed that patients with schizophrenia (SZ) have facial recognition difficulties and a reduced visual evoked N170 response to human faces. However, detailed neurophysiological evidence of this face processing deficit in SZ with a higher spatial resolution has yet to be acqu...

journal_title：Frontiers in psychiatry

authors： Ohara N,Hirano Y,Oribe N,Tamura S,Nakamura I,Hirano S,Tsuchimoto R,Ueno T,Togao O,Hiwatashi A,Nakao T,Onitsuka T

更新日期：2020-09-03 00:00:00

abstract：:There is minimal knowledge about the impact of large-scale epidemics on community mental health, particularly during the acute phase. This gap in knowledge means we are critically ill-equipped to support communities as they face the unprecedented COVID-19 pandemic. This study aimed to provide data urgently needed to i...

journal_title：Frontiers in psychiatry

authors： Dawel A,Shou Y,Smithson M,Cherbuin N,Banfield M,Calear AL,Farrer LM,Gray D,Gulliver A,Housen T,McCallum SM,Morse AR,Murray K,Newman E,Rodney Harris RM,Batterham PJ

更新日期：2020-10-06 00:00:00

abstract：:Objective: We aimed to conduct a comparative analysis of the psychological stress experienced by healthcare workers, frontline workers, and the general public and to assess the factors associated with psychological stress in each of these groups. Methods: We conducted an online survey targeting healthcare workers, fro...

journal_title：Frontiers in psychiatry

authors： Luan R,Pu W,Dai L,Yang R,Wang P

更新日期：2020-12-01 00:00:00

abstract：:Objective: To evaluate perceived needs and difficulties related to instruments for assessing work ability in individuals with mental disorders. Method: We conducted an online survey of 104 German-speaking medico-legal experts (forensic psychiatric and psychology experts, insurance physicians) and therapists. Results: ...

journal_title：Frontiers in psychiatry

authors： Schleifer R,Gamma A,Warnke I,Jabat M,Rössler W,Liebrenz M

更新日期：2018-09-25 00:00:00

abstract：BACKGROUND:Females are twice as likely as males to experience depression. Recent findings indicate a relationship linking inflammation with depression. Whether the higher prevalence of depression in women is sex-specific or if inflammation contributes to a higher prevalence of depression in females is unclear. Thus, th...

journal_title：Frontiers in psychiatry

authors： Birur B,Amrock EM,Shelton RC,Li L

更新日期：2017-06-16 00:00:00

abstract：:It has been proposed that compulsive drug seeking reflects an underlying dysregulation in adaptive behavior that favors habitual (automatic and inflexible) over goal-directed (deliberative and highly flexible) action selection. Rodent studies have established that repeated exposure to cocaine or amphetamine facilitate...

journal_title：Frontiers in psychiatry

authors： Halbout B,Liu AT,Ostlund SB

更新日期：2016-03-21 00:00:00

abstract：:Transcranial direct current stimulation (tDCS) can enhance cognitive control functions including attention and top-down regulation over negative affect and substance craving in both healthy and clinical populations, including early abstinent (∼1.5 h) smokers. The aim of this study was to assess whether tDCS modulates ...

journal_title：Frontiers in psychiatry

authors： Xu J,Fregni F,Brody AL,Rahman AS

更新日期：2013-09-20 00:00:00

abstract：AIM:In efforts to develop reliable methods to detect the likelihood of impending suicidal behaviors, we have proposed the following. OBJECTIVE:To gain a deeper understanding of the state of suicide risk by determining the combination of variables that distinguishes between groups with and without suicide risk. METHOD...

journal_title：Frontiers in psychiatry

authors： Morales S,Barros J,Echávarri O,García F,Osses A,Moya C,Maino MP,Fischman R,Núñez C,Szmulewicz T,Tomicic A

更新日期：2017-02-02 00:00:00

abstract：:Background: Psychiatric comorbidity is common in gambling disorder, a condition with low rates of treatment seeking. There is a paucity of documented nationwide data on gambling disorder and its co-occurring psychiatric comorbidities in the health care system. Methods: This is a nationwide register-based study of all ...

journal_title：Frontiers in psychiatry

authors： Håkansson A,Karlsson A,Widinghoff C

更新日期：2018-09-07 00:00:00

abstract：:Computational methods are increasingly being applied to the study of psychiatric disorders. Often, this involves fitting models to the behavior of individuals with subclinical character traits that are known vulnerability factors for the development of psychiatric conditions. Anxiety disorders can be examined with ref...

journal_title：Frontiers in psychiatry

authors： Raymond JG,Steele JD,Seriès P

更新日期：2017-01-23 00:00:00

abstract：:Post-traumatic stress disorder (PTSD) is a heterogeneous disorder that affects individuals exposed to trauma (e.g., combat, interpersonal violence, and natural disasters). It is characterized by hyperarousal, intrusive reminders of the trauma, avoidance of trauma-related cues, and negative cognition and mood. This het...

journal_title：Frontiers in psychiatry

authors： Briscione MA,Jovanovic T,Norrholm SD

更新日期：2014-07-21 00:00:00

abstract：:Globally, 52.9 million children under the age of 5 experience a developmental disability, such as sensory impairment, intellectual disability, and autism spectrum disorders. Of these 95% live in low-and-middle-income countries. Most of these children lack access to care. In light of the growing evidence that caregiver...

journal_title：Frontiers in psychiatry

authors： Salomone E,Pacione L,Shire S,Brown FL,Reichow B,Servili C

更新日期：2019-11-11 00:00:00