Abstract:
:Sodium dodecyl sulphate-supported iron silicophosphate (SDS/FeSP) nanocomposite was successfully fabricated by the co-precipitation method. The SDS/FeSP nanocomposite was investigated as a drug carrier for ondansetron. The cumulative drug release of ondansetron was observed at various pH values for different time intervals, i.e., from 20 min to 48 h. A ranking of the drug release was observed at different pHs; pH 2.2 > saline (pH 5.5) > pH 7.4 > pH 9.4 > distilled water. Maximum release of encapsulated drug was found to be about 45.38% at pH 2.2. The cell viability tests of SDS/FeSP nanocomposite concluded that SDS/FeSP nanocomposite was non-cytotoxic in nature.
journal_name
Int J Environ Res Public Healthauthors
Sharma G,Naushad M,Thakur B,Kumar A,Negi P,Saini R,Chahal A,Kumar A,Stadler FJ,Aqil UMHdoi
10.3390/ijerph15030414subject
Has Abstractpub_date
2018-02-27 00:00:00issue
3eissn
1661-7827issn
1660-4601pii
ijerph15030414journal_volume
15pub_type
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